TY  - JOUR
AU  - Ardalić, Daniela
AU  - Stefanović, Aleksandra
AU  - Kotur-Stevuljević, Jelena
AU  - Vujović, Ana
AU  - Spasić, Slavica
AU  - Spasojević-Kalimanovska, Vesna
AU  - Jelić-Ivanović, Zorana
AU  - Mandić-Marković, Vesna
AU  - Miković, Željko
AU  - Cerović, Nikola
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2143
AB  - Background. As a physiological condition closely linked with increased susceptibility to oxidative stress, pregnancy can be further compromised by cigarette smoking. Inadequate nutrition and reduced intake of antioxidants can also disrupt the prooxidant/antioxidant relationship and contribute to oxidative stress. Increased oxidative stress during pregnancy may be involved in several complications of pregnancy, such as preterm labor, fetal growth restriction, preeclampsia and Miscarriage. Objectives. The aim of this study was to investigate the influence of maternal smoking habits before pregnancy on the parameters of oxidative stress and the antioxidative defense system, lipid profile parameters and paraoxonase-1 (PON1) activity during the third trimester of uncomplicated pregnancies. Material and Methods. Healthy pregnant women (n = 86) were divided into non-smoking and smoking groups, and into groups taking vitamin supplements and not taking them. Oxidative damage was measured through the levels of thiobarbituric acid-reacting substances (TBARS) and plasma antioxidant status was evaluated by measuring total antioxidant capacity (TAC). Results. TBARS concetration was significantly higher (p  lt  0.05) and PON1 activity was significantly lower (p  lt  0.05) in the smokers' group. No significant differences were found in the investigated parameters in relation to vitamin supplement intake. Conclusions. Habitual smoking before pregnancy is associated with increased oxidative stress. Vitamin supplementation has no effect on the oxidative stress status of healthy pregnant women.
PB  - Wroclaw Medical Univ, Wroclaw
T2  - Advances in Clinical and Experimental Medicine
T1  - The Influence of Maternal Smoking Habits Before Pregnancy and Antioxidative Supplementation During Pregnancy on Oxidative Stress Status in a Non-Complicated Pregnancy
VL  - 23
IS  - 4
SP  - 575
EP  - 583
DO  - 10.17219/acem/37226
ER  - 

@article{
author = "Ardalić, Daniela and Stefanović, Aleksandra and Kotur-Stevuljević, Jelena and Vujović, Ana and Spasić, Slavica and Spasojević-Kalimanovska, Vesna and Jelić-Ivanović, Zorana and Mandić-Marković, Vesna and Miković, Željko and Cerović, Nikola",
year = "2014",
abstract = "Background. As a physiological condition closely linked with increased susceptibility to oxidative stress, pregnancy can be further compromised by cigarette smoking. Inadequate nutrition and reduced intake of antioxidants can also disrupt the prooxidant/antioxidant relationship and contribute to oxidative stress. Increased oxidative stress during pregnancy may be involved in several complications of pregnancy, such as preterm labor, fetal growth restriction, preeclampsia and Miscarriage. Objectives. The aim of this study was to investigate the influence of maternal smoking habits before pregnancy on the parameters of oxidative stress and the antioxidative defense system, lipid profile parameters and paraoxonase-1 (PON1) activity during the third trimester of uncomplicated pregnancies. Material and Methods. Healthy pregnant women (n = 86) were divided into non-smoking and smoking groups, and into groups taking vitamin supplements and not taking them. Oxidative damage was measured through the levels of thiobarbituric acid-reacting substances (TBARS) and plasma antioxidant status was evaluated by measuring total antioxidant capacity (TAC). Results. TBARS concetration was significantly higher (p  lt  0.05) and PON1 activity was significantly lower (p  lt  0.05) in the smokers' group. No significant differences were found in the investigated parameters in relation to vitamin supplement intake. Conclusions. Habitual smoking before pregnancy is associated with increased oxidative stress. Vitamin supplementation has no effect on the oxidative stress status of healthy pregnant women.",
publisher = "Wroclaw Medical Univ, Wroclaw",
journal = "Advances in Clinical and Experimental Medicine",
title = "The Influence of Maternal Smoking Habits Before Pregnancy and Antioxidative Supplementation During Pregnancy on Oxidative Stress Status in a Non-Complicated Pregnancy",
volume = "23",
number = "4",
pages = "575-583",
doi = "10.17219/acem/37226"
}

Ardalić, D., Stefanović, A., Kotur-Stevuljević, J., Vujović, A., Spasić, S., Spasojević-Kalimanovska, V., Jelić-Ivanović, Z., Mandić-Marković, V., Miković, Ž.,& Cerović, N.. (2014). The Influence of Maternal Smoking Habits Before Pregnancy and Antioxidative Supplementation During Pregnancy on Oxidative Stress Status in a Non-Complicated Pregnancy. in Advances in Clinical and Experimental Medicine
Wroclaw Medical Univ, Wroclaw., 23(4), 575-583.
https://doi.org/10.17219/acem/37226

Ardalić D, Stefanović A, Kotur-Stevuljević J, Vujović A, Spasić S, Spasojević-Kalimanovska V, Jelić-Ivanović Z, Mandić-Marković V, Miković Ž, Cerović N. The Influence of Maternal Smoking Habits Before Pregnancy and Antioxidative Supplementation During Pregnancy on Oxidative Stress Status in a Non-Complicated Pregnancy. in Advances in Clinical and Experimental Medicine. 2014;23(4):575-583.
doi:10.17219/acem/37226 .

Ardalić, Daniela, Stefanović, Aleksandra, Kotur-Stevuljević, Jelena, Vujović, Ana, Spasić, Slavica, Spasojević-Kalimanovska, Vesna, Jelić-Ivanović, Zorana, Mandić-Marković, Vesna, Miković, Željko, Cerović, Nikola, "The Influence of Maternal Smoking Habits Before Pregnancy and Antioxidative Supplementation During Pregnancy on Oxidative Stress Status in a Non-Complicated Pregnancy" in Advances in Clinical and Experimental Medicine, 23, no. 4 (2014):575-583,
https://doi.org/10.17219/acem/37226 . .

TY  - JOUR
AU  - Vujović, Ana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Bogavac-Stanojević, Nataša
AU  - Kotur-Stevuljević, Jelena
AU  - Sopić, Miron
AU  - Stefanović, Aleksandra
AU  - Baralić, Ivana
AU  - Đorđević, Brižita
AU  - Jelić-Ivanović, Zorana
AU  - Spasić, Slavica
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1919
AB  - The purpose of the present study was to examine the effect of physical training on the gene expression levels of Cu/Zn superoxide dismutase (Cu/Zn SOD) and Mn superoxide dismutase (Mn SOD) in young soccer players at the beginning of their professional careers. The non-trained young men underwent a professional soccer training program of 12 weeks. Blood was obtained at two time points: before and after the 12-week endurance soccer training. Plasmatic superoxide dismutase (SOD) activity, concentration of sulfhydryl (SH) groups, superoxide anion (O-2(.-)), malondialdehyde (MDA), and advanced oxidation protein product (AOPP) were determined. Messenger RNA (mRNA) relative levels of SOD isoenzymes were measured in peripheral blood mononuclear cells by Real-time PCR. After 12-week training, the soccer group experienced a significant decrease in plasmatic SOD activity and increase of O-2(.-) concentration. Concentration of SH groups, MDA and AOPP were not affected by physical training, although they showed a trend to increase. Cu/Zn SOD mRNA expression levels were stable during the endurance training period but Mn SOD mRNA levels were significantly higher after the training period The variation in Mn SOD mRNA levels was dependent on MDA concentration. Negative prediction of AIDA concentration on Mn SOD mRNA expression levels remained significant after inclusion of all the other oxidative stress status parameters in a multiple regression model (p = 0.017). Positive prediction of Cu/Zn SOD mRNA levels on plasmatic SOD activity remained significant after inclusion of MDA, log O-2(.-) and AOPP concentrations in a multiple regression model (p = 0.025). Intensive endurance soccer training stimulated a beneficial increase in lymphocyte Mn SOD rather than in Cu/Zn SOD mRNA expression levels. An interaction between the oxidative stress/antioxidative defence status parameters in blood and gene expression levels of Cu/Zn SOD and Mn SOD in PBMCs was also observed.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Biotechnology & Biotechnological Equipment
T1  - Lymphocyte cu/znsod and mnsod gene expression responses to intensive endurance soccer training
VL  - 27
IS  - 3
SP  - 3843
EP  - 3847
DO  - 10.5504/BBEQ.2012.0144
ER  - 

@article{
author = "Vujović, Ana and Spasojević-Kalimanovska, Vesna and Bogavac-Stanojević, Nataša and Kotur-Stevuljević, Jelena and Sopić, Miron and Stefanović, Aleksandra and Baralić, Ivana and Đorđević, Brižita and Jelić-Ivanović, Zorana and Spasić, Slavica",
year = "2013",
abstract = "The purpose of the present study was to examine the effect of physical training on the gene expression levels of Cu/Zn superoxide dismutase (Cu/Zn SOD) and Mn superoxide dismutase (Mn SOD) in young soccer players at the beginning of their professional careers. The non-trained young men underwent a professional soccer training program of 12 weeks. Blood was obtained at two time points: before and after the 12-week endurance soccer training. Plasmatic superoxide dismutase (SOD) activity, concentration of sulfhydryl (SH) groups, superoxide anion (O-2(.-)), malondialdehyde (MDA), and advanced oxidation protein product (AOPP) were determined. Messenger RNA (mRNA) relative levels of SOD isoenzymes were measured in peripheral blood mononuclear cells by Real-time PCR. After 12-week training, the soccer group experienced a significant decrease in plasmatic SOD activity and increase of O-2(.-) concentration. Concentration of SH groups, MDA and AOPP were not affected by physical training, although they showed a trend to increase. Cu/Zn SOD mRNA expression levels were stable during the endurance training period but Mn SOD mRNA levels were significantly higher after the training period The variation in Mn SOD mRNA levels was dependent on MDA concentration. Negative prediction of AIDA concentration on Mn SOD mRNA expression levels remained significant after inclusion of all the other oxidative stress status parameters in a multiple regression model (p = 0.017). Positive prediction of Cu/Zn SOD mRNA levels on plasmatic SOD activity remained significant after inclusion of MDA, log O-2(.-) and AOPP concentrations in a multiple regression model (p = 0.025). Intensive endurance soccer training stimulated a beneficial increase in lymphocyte Mn SOD rather than in Cu/Zn SOD mRNA expression levels. An interaction between the oxidative stress/antioxidative defence status parameters in blood and gene expression levels of Cu/Zn SOD and Mn SOD in PBMCs was also observed.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Biotechnology & Biotechnological Equipment",
title = "Lymphocyte cu/znsod and mnsod gene expression responses to intensive endurance soccer training",
volume = "27",
number = "3",
pages = "3843-3847",
doi = "10.5504/BBEQ.2012.0144"
}

Vujović, A., Spasojević-Kalimanovska, V., Bogavac-Stanojević, N., Kotur-Stevuljević, J., Sopić, M., Stefanović, A., Baralić, I., Đorđević, B., Jelić-Ivanović, Z.,& Spasić, S.. (2013). Lymphocyte cu/znsod and mnsod gene expression responses to intensive endurance soccer training. in Biotechnology & Biotechnological Equipment
Taylor & Francis Ltd, Abingdon., 27(3), 3843-3847.
https://doi.org/10.5504/BBEQ.2012.0144

Vujović A, Spasojević-Kalimanovska V, Bogavac-Stanojević N, Kotur-Stevuljević J, Sopić M, Stefanović A, Baralić I, Đorđević B, Jelić-Ivanović Z, Spasić S. Lymphocyte cu/znsod and mnsod gene expression responses to intensive endurance soccer training. in Biotechnology & Biotechnological Equipment. 2013;27(3):3843-3847.
doi:10.5504/BBEQ.2012.0144 .

Vujović, Ana, Spasojević-Kalimanovska, Vesna, Bogavac-Stanojević, Nataša, Kotur-Stevuljević, Jelena, Sopić, Miron, Stefanović, Aleksandra, Baralić, Ivana, Đorđević, Brižita, Jelić-Ivanović, Zorana, Spasić, Slavica, "Lymphocyte cu/znsod and mnsod gene expression responses to intensive endurance soccer training" in Biotechnology & Biotechnological Equipment, 27, no. 3 (2013):3843-3847,
https://doi.org/10.5504/BBEQ.2012.0144 . .

TY  - JOUR
AU  - Vujović, Ana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Bogavac-Stanojević, Nataša
AU  - Spasić, Slavica
AU  - Kotur-Stevuljević, Jelena
AU  - Jelić-Ivanović, Zorana
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1945
AB  - In the current study, two RNA isolation techniques were compared and their abilities to produce high-quality RNA were evaluated. mRNA expression profiles of SOD1 (Cu/Zn superoxide dismutase) and SOD2 (Mn superoxide dismutase) genes were measured by real-time PCR. From a pool of fresh human citrate-whole blood and ten healthy individuals, RNA was isolated with the TRIzol (TM) extraction method (TRI) and with the ABI PRISM (TM) 6100 Nucleic AcidPrepStation (ABI). The concentration and purity of RNA extracts were determined spectrophotometrically. RNA integrity was evaluated by electrophoresis on a 1% agarose gel. PCR was performed on a 7500 Real-Time PCR System. The student's t-test was applied to compare normally distributed variables. Both protocols gave similar RNA quantities when adjusted to the initial blood volume. Relative quantification values obtained from the TRI method for SOD1 were significantly higher (p lt 0.01) and for SOD2 were significantly lower (p lt 0.05) as compared to those obtained from the ABI method, respectively. Coefficients of variation (CV) for gene expression parameters in SOD1 and SOD2 analyses were lower when the TRI method was used. The TRI method was generally more consistent in yielding pure RNA in comparison to the ABI and better reproducibility in gene expression analyses was apparent.
PB  - Natl Inst Science Communication-Niscair, New Delhi
T2  - Indian Journal of Biotechnology
T1  - Comparison of two RNA isolation methods' for determination of SOD1 and SOD2 gene expression in human blood and mononuclear cells
VL  - 12
IS  - 4
SP  - 468
EP  - 474
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1945
ER  - 

@article{
author = "Vujović, Ana and Spasojević-Kalimanovska, Vesna and Bogavac-Stanojević, Nataša and Spasić, Slavica and Kotur-Stevuljević, Jelena and Jelić-Ivanović, Zorana",
year = "2013",
abstract = "In the current study, two RNA isolation techniques were compared and their abilities to produce high-quality RNA were evaluated. mRNA expression profiles of SOD1 (Cu/Zn superoxide dismutase) and SOD2 (Mn superoxide dismutase) genes were measured by real-time PCR. From a pool of fresh human citrate-whole blood and ten healthy individuals, RNA was isolated with the TRIzol (TM) extraction method (TRI) and with the ABI PRISM (TM) 6100 Nucleic AcidPrepStation (ABI). The concentration and purity of RNA extracts were determined spectrophotometrically. RNA integrity was evaluated by electrophoresis on a 1% agarose gel. PCR was performed on a 7500 Real-Time PCR System. The student's t-test was applied to compare normally distributed variables. Both protocols gave similar RNA quantities when adjusted to the initial blood volume. Relative quantification values obtained from the TRI method for SOD1 were significantly higher (p lt 0.01) and for SOD2 were significantly lower (p lt 0.05) as compared to those obtained from the ABI method, respectively. Coefficients of variation (CV) for gene expression parameters in SOD1 and SOD2 analyses were lower when the TRI method was used. The TRI method was generally more consistent in yielding pure RNA in comparison to the ABI and better reproducibility in gene expression analyses was apparent.",
publisher = "Natl Inst Science Communication-Niscair, New Delhi",
journal = "Indian Journal of Biotechnology",
title = "Comparison of two RNA isolation methods' for determination of SOD1 and SOD2 gene expression in human blood and mononuclear cells",
volume = "12",
number = "4",
pages = "468-474",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1945"
}

Vujović, A., Spasojević-Kalimanovska, V., Bogavac-Stanojević, N., Spasić, S., Kotur-Stevuljević, J.,& Jelić-Ivanović, Z.. (2013). Comparison of two RNA isolation methods' for determination of SOD1 and SOD2 gene expression in human blood and mononuclear cells. in Indian Journal of Biotechnology
Natl Inst Science Communication-Niscair, New Delhi., 12(4), 468-474.
https://hdl.handle.net/21.15107/rcub_farfar_1945

Vujović A, Spasojević-Kalimanovska V, Bogavac-Stanojević N, Spasić S, Kotur-Stevuljević J, Jelić-Ivanović Z. Comparison of two RNA isolation methods' for determination of SOD1 and SOD2 gene expression in human blood and mononuclear cells. in Indian Journal of Biotechnology. 2013;12(4):468-474.
https://hdl.handle.net/21.15107/rcub_farfar_1945 .

Vujović, Ana, Spasojević-Kalimanovska, Vesna, Bogavac-Stanojević, Nataša, Spasić, Slavica, Kotur-Stevuljević, Jelena, Jelić-Ivanović, Zorana, "Comparison of two RNA isolation methods' for determination of SOD1 and SOD2 gene expression in human blood and mononuclear cells" in Indian Journal of Biotechnology, 12, no. 4 (2013):468-474,
https://hdl.handle.net/21.15107/rcub_farfar_1945 .

TY  - JOUR
AU  - Kotur-Stevuljević, Jelena
AU  - Peco-Antić, Amira
AU  - Spasić, Slavica
AU  - Stefanović, Aleksandra
AU  - Paripović, Dušan
AU  - Kostić, Mirjana
AU  - Vasić, Dragan
AU  - Vujović, Ana
AU  - Jelić-Ivanović, Zorana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Kornić-Ristovski, Danijela
PY  - 2013
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1943
AB  - The roles of dyslipidemia and oxidative stress in the early phases of atherosclerosis were tested in children with chronic kidney disease (CKD). Intima media thickness of common carotid arteries (cIMT) is used as a measure of early atherosclerosis. Fifty-two pediatric CKD patients were enrolled in the study (10 with chronic renal failure [CRF], 22 with a renal transplant [RT], 20 with chronic hemodialysis (cHD) patients, and 36 healthy children (control group, CG). Lipid status, oxidative stress, and paraoxonase 1 (PON1) status were assessed. cIMT was measured by ultrasound, adjusted for age and sex, and presented as standard deviation scores (SDS). Children with CKD had disturbed lipid content, which was most pronounced in cHD children, with higher free cholesterol and triglycerides compared with healthy children. Oxidative stress was markedly increased (malodialdehyde [MDA, mu mol/L]: CRF 1.50 +/- 0.26, RT 1.55 +/- 0.40, cHD 1.77 +/- 0.34, CG 0.97 +/- 0.33, p  lt  0.001) and antioxidative defense was compromised (superoxide dismutase [SOD, U/L]: CG 120 +/- 21, CRF 84 +/- 25, RT 93 +/- 12, cHD 119 +/- 37, p  lt  0.001). Multiple linear regression analysis showed that a model that included disease duration, blood pressure, urea, lipid, and oxidative status parameters accounted for more than 90% of the variability of cIMT-SDS. Early atherosclerosis in CKD children is caused, at least in part, by dyslipidemia and oxidative stress. Monitoring of vessel wall changes, along with assessment of oxidative stress status and high density lipoprotein (HDL) functionality is necessary to ensure better therapeutic strategies for delaying atherosclerotic changes in their asymptomatic phase.
PB  - Springer, New York
T2  - Pediatric Nephrology
T1  - Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease
VL  - 28
IS  - 2
SP  - 295
EP  - 303
DO  - 10.1007/s00467-012-2323-5
ER  - 

@article{
author = "Kotur-Stevuljević, Jelena and Peco-Antić, Amira and Spasić, Slavica and Stefanović, Aleksandra and Paripović, Dušan and Kostić, Mirjana and Vasić, Dragan and Vujović, Ana and Jelić-Ivanović, Zorana and Spasojević-Kalimanovska, Vesna and Kornić-Ristovski, Danijela",
year = "2013",
abstract = "The roles of dyslipidemia and oxidative stress in the early phases of atherosclerosis were tested in children with chronic kidney disease (CKD). Intima media thickness of common carotid arteries (cIMT) is used as a measure of early atherosclerosis. Fifty-two pediatric CKD patients were enrolled in the study (10 with chronic renal failure [CRF], 22 with a renal transplant [RT], 20 with chronic hemodialysis (cHD) patients, and 36 healthy children (control group, CG). Lipid status, oxidative stress, and paraoxonase 1 (PON1) status were assessed. cIMT was measured by ultrasound, adjusted for age and sex, and presented as standard deviation scores (SDS). Children with CKD had disturbed lipid content, which was most pronounced in cHD children, with higher free cholesterol and triglycerides compared with healthy children. Oxidative stress was markedly increased (malodialdehyde [MDA, mu mol/L]: CRF 1.50 +/- 0.26, RT 1.55 +/- 0.40, cHD 1.77 +/- 0.34, CG 0.97 +/- 0.33, p  lt  0.001) and antioxidative defense was compromised (superoxide dismutase [SOD, U/L]: CG 120 +/- 21, CRF 84 +/- 25, RT 93 +/- 12, cHD 119 +/- 37, p  lt  0.001). Multiple linear regression analysis showed that a model that included disease duration, blood pressure, urea, lipid, and oxidative status parameters accounted for more than 90% of the variability of cIMT-SDS. Early atherosclerosis in CKD children is caused, at least in part, by dyslipidemia and oxidative stress. Monitoring of vessel wall changes, along with assessment of oxidative stress status and high density lipoprotein (HDL) functionality is necessary to ensure better therapeutic strategies for delaying atherosclerotic changes in their asymptomatic phase.",
publisher = "Springer, New York",
journal = "Pediatric Nephrology",
title = "Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease",
volume = "28",
number = "2",
pages = "295-303",
doi = "10.1007/s00467-012-2323-5"
}

Kotur-Stevuljević, J., Peco-Antić, A., Spasić, S., Stefanović, A., Paripović, D., Kostić, M., Vasić, D., Vujović, A., Jelić-Ivanović, Z., Spasojević-Kalimanovska, V.,& Kornić-Ristovski, D.. (2013). Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease. in Pediatric Nephrology
Springer, New York., 28(2), 295-303.
https://doi.org/10.1007/s00467-012-2323-5

Kotur-Stevuljević J, Peco-Antić A, Spasić S, Stefanović A, Paripović D, Kostić M, Vasić D, Vujović A, Jelić-Ivanović Z, Spasojević-Kalimanovska V, Kornić-Ristovski D. Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease. in Pediatric Nephrology. 2013;28(2):295-303.
doi:10.1007/s00467-012-2323-5 .

Kotur-Stevuljević, Jelena, Peco-Antić, Amira, Spasić, Slavica, Stefanović, Aleksandra, Paripović, Dušan, Kostić, Mirjana, Vasić, Dragan, Vujović, Ana, Jelić-Ivanović, Zorana, Spasojević-Kalimanovska, Vesna, Kornić-Ristovski, Danijela, "Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease" in Pediatric Nephrology, 28, no. 2 (2013):295-303,
https://doi.org/10.1007/s00467-012-2323-5 . .

TY  - JOUR
AU  - Kotur-Stevuljević, Jelena
AU  - Simić-Ogrizović, Sanja
AU  - Dopsaj, Violeta
AU  - Stefanović, Aleksandra
AU  - Vujović, Ana
AU  - Ivanić-Corlomanović, Tatjana
AU  - Spasić, Slavica
AU  - Spasojević-Kalimanovska, Vesna
AU  - Jelić-Ivanović, Zorana
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1623
AB  - Background: Atherosclerosis is the main cause of mortality in end stage renal disease (ESRD) patients. Design and methods: Malnutrition, inflammation and diminished paraoxonase activity were used to calculate the sum of risk factors for atherosclerosis development in a cohort of 141 chronic renal disease patients. Kaplan-Meier survival analysis was implemented to assess risk of death. Results: Kaplan-Meier analysis (Log rank = 12.06, P = 0.0072) showed higher risk of death with increasing number of risk factors in haemodialysis patients. Conclusions: Malnutrition in combination with inflammation and oxidative stress is associated with higher mortality in patients on long-term haemodialysis.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Clinical Biochemistry
T1  - A hazardous link between malnutrition, inflammation and oxidative stress in renal patients
VL  - 45
IS  - 15
SP  - 1202
EP  - 1205
DO  - 10.1016/j.clinbiochem.2012.04.021
ER  - 

@article{
author = "Kotur-Stevuljević, Jelena and Simić-Ogrizović, Sanja and Dopsaj, Violeta and Stefanović, Aleksandra and Vujović, Ana and Ivanić-Corlomanović, Tatjana and Spasić, Slavica and Spasojević-Kalimanovska, Vesna and Jelić-Ivanović, Zorana",
year = "2012",
abstract = "Background: Atherosclerosis is the main cause of mortality in end stage renal disease (ESRD) patients. Design and methods: Malnutrition, inflammation and diminished paraoxonase activity were used to calculate the sum of risk factors for atherosclerosis development in a cohort of 141 chronic renal disease patients. Kaplan-Meier survival analysis was implemented to assess risk of death. Results: Kaplan-Meier analysis (Log rank = 12.06, P = 0.0072) showed higher risk of death with increasing number of risk factors in haemodialysis patients. Conclusions: Malnutrition in combination with inflammation and oxidative stress is associated with higher mortality in patients on long-term haemodialysis.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Clinical Biochemistry",
title = "A hazardous link between malnutrition, inflammation and oxidative stress in renal patients",
volume = "45",
number = "15",
pages = "1202-1205",
doi = "10.1016/j.clinbiochem.2012.04.021"
}

Kotur-Stevuljević, J., Simić-Ogrizović, S., Dopsaj, V., Stefanović, A., Vujović, A., Ivanić-Corlomanović, T., Spasić, S., Spasojević-Kalimanovska, V.,& Jelić-Ivanović, Z.. (2012). A hazardous link between malnutrition, inflammation and oxidative stress in renal patients. in Clinical Biochemistry
Pergamon-Elsevier Science Ltd, Oxford., 45(15), 1202-1205.
https://doi.org/10.1016/j.clinbiochem.2012.04.021

Kotur-Stevuljević J, Simić-Ogrizović S, Dopsaj V, Stefanović A, Vujović A, Ivanić-Corlomanović T, Spasić S, Spasojević-Kalimanovska V, Jelić-Ivanović Z. A hazardous link between malnutrition, inflammation and oxidative stress in renal patients. in Clinical Biochemistry. 2012;45(15):1202-1205.
doi:10.1016/j.clinbiochem.2012.04.021 .

Kotur-Stevuljević, Jelena, Simić-Ogrizović, Sanja, Dopsaj, Violeta, Stefanović, Aleksandra, Vujović, Ana, Ivanić-Corlomanović, Tatjana, Spasić, Slavica, Spasojević-Kalimanovska, Vesna, Jelić-Ivanović, Zorana, "A hazardous link between malnutrition, inflammation and oxidative stress in renal patients" in Clinical Biochemistry, 45, no. 15 (2012):1202-1205,
https://doi.org/10.1016/j.clinbiochem.2012.04.021 . .

TY  - JOUR
AU  - Stefanović, Aleksandra
AU  - Ardalić, Daniela
AU  - Kotur-Stevuljević, Jelena
AU  - Vujović, Ana
AU  - Spasić, Slavica
AU  - Spasojević-Kalimanovska, Vesna
AU  - Jelić-Ivanović, Zorana
AU  - Mandić-Marković, Vesna
AU  - Miković, Željko
AU  - Cerović, Nikola
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1694
AB  - The purpose of the present study was to determine changes in plasma paraoxonase-1 activity (an indicator of paraoxonase phenotype) throughout normal pregnancy and its relationship with maternal oxidative stress status. The frequencies of the paraoxonase-1 phenotype in the studied population were determined using a two-substrate (paraoxon/diazoxon) activity method. As a parameter of oxidative stress status we measured the redox balance. Paraoxonase-1 activity significantly decreased at gestational week 32. In addition, the lipid profile was more atherogenic. Redox balance was significantly increased across gestational weeks. There were independent direct associations between maternal smoking habits before pregnancy, glucose concentrations and redox balance with PON1 activity in the third trimester. This study shows that pregnancy is followed by a decrease in PON1 activity and increased risk for development of cardiovascular diseases. We conclude that changes in paraoxonase-1 status during pregnancy are associated with maternal oxidative stress status and smoking habits.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Research in Microbiology
T1  - Longitudinal changes in PON1 activities, PON1 phenotype distribution and oxidative status throughout normal pregnancy
VL  - 33
IS  - 1
SP  - 20
EP  - 26
DO  - 10.1016/j.reprotox.2011.10.009
ER  - 

@article{
author = "Stefanović, Aleksandra and Ardalić, Daniela and Kotur-Stevuljević, Jelena and Vujović, Ana and Spasić, Slavica and Spasojević-Kalimanovska, Vesna and Jelić-Ivanović, Zorana and Mandić-Marković, Vesna and Miković, Željko and Cerović, Nikola",
year = "2012",
abstract = "The purpose of the present study was to determine changes in plasma paraoxonase-1 activity (an indicator of paraoxonase phenotype) throughout normal pregnancy and its relationship with maternal oxidative stress status. The frequencies of the paraoxonase-1 phenotype in the studied population were determined using a two-substrate (paraoxon/diazoxon) activity method. As a parameter of oxidative stress status we measured the redox balance. Paraoxonase-1 activity significantly decreased at gestational week 32. In addition, the lipid profile was more atherogenic. Redox balance was significantly increased across gestational weeks. There were independent direct associations between maternal smoking habits before pregnancy, glucose concentrations and redox balance with PON1 activity in the third trimester. This study shows that pregnancy is followed by a decrease in PON1 activity and increased risk for development of cardiovascular diseases. We conclude that changes in paraoxonase-1 status during pregnancy are associated with maternal oxidative stress status and smoking habits.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Research in Microbiology",
title = "Longitudinal changes in PON1 activities, PON1 phenotype distribution and oxidative status throughout normal pregnancy",
volume = "33",
number = "1",
pages = "20-26",
doi = "10.1016/j.reprotox.2011.10.009"
}

Stefanović, A., Ardalić, D., Kotur-Stevuljević, J., Vujović, A., Spasić, S., Spasojević-Kalimanovska, V., Jelić-Ivanović, Z., Mandić-Marković, V., Miković, Ž.,& Cerović, N.. (2012). Longitudinal changes in PON1 activities, PON1 phenotype distribution and oxidative status throughout normal pregnancy. in Research in Microbiology
Pergamon-Elsevier Science Ltd, Oxford., 33(1), 20-26.
https://doi.org/10.1016/j.reprotox.2011.10.009

Stefanović A, Ardalić D, Kotur-Stevuljević J, Vujović A, Spasić S, Spasojević-Kalimanovska V, Jelić-Ivanović Z, Mandić-Marković V, Miković Ž, Cerović N. Longitudinal changes in PON1 activities, PON1 phenotype distribution and oxidative status throughout normal pregnancy. in Research in Microbiology. 2012;33(1):20-26.
doi:10.1016/j.reprotox.2011.10.009 .

Stefanović, Aleksandra, Ardalić, Daniela, Kotur-Stevuljević, Jelena, Vujović, Ana, Spasić, Slavica, Spasojević-Kalimanovska, Vesna, Jelić-Ivanović, Zorana, Mandić-Marković, Vesna, Miković, Željko, Cerović, Nikola, "Longitudinal changes in PON1 activities, PON1 phenotype distribution and oxidative status throughout normal pregnancy" in Research in Microbiology, 33, no. 1 (2012):20-26,
https://doi.org/10.1016/j.reprotox.2011.10.009 . .

TY  - JOUR
AU  - Stefanović, Aleksandra
AU  - Kotur-Stevuljević, Jelena
AU  - Vujović, Ana
AU  - Spasić, Slavica
AU  - Spasojević-Kalimanovska, Vesna
AU  - Jelić-Ivanović, Zorana
AU  - Martinović, Jelena
AU  - Ardalić, Daniela
AU  - Mandić-Marković, Vesna
AU  - Miković, Željko
AU  - Cerović, Nikola
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1635
AB  - Background: Pregnancy is a stressful condition linked with altered lipid profile, increased oxidative stress and increased inflammation processes. The purpose of the present study was to determine the associations between those alterations with increased weight gain during pregnancy. Methods: The atherogenic index of plasma (AIP) and oxidative stress status parameters were determinated in 50 healthy and 172 pregnant women with non-complicated pregnancy. Pregnant women were divided in four groups according to body mass index (BMI) values (BMI quartiles). Results: Oxidative stress parameters were significantly lower in the control group compared with all the pregnant women quartiles. Unexpectedly, differences in oxidative stress parameters between BMI quartiles groups were not significant. The antioxidant defence parameters remained quite similar in the different BMI quartiles. Weight gain and paraoxonase-1 (PON1) activities were independently associated with increased AIP while weight gain and triglyceride concentration were found to be significant predictors of PON1 activities. Conclusions: The results of our current study indicate the association of maternal weight gain during pregnancy and altered lipid profile, elevated oxidative stress and changed antioxidative capacity of PON1. Taken together all these facts indicate possible increased risk of cardiovascular disease (CVD) development in later life if the weight gain during pregnancy is excessive.
PB  - Walter de Gruyter Gmbh, Berlin
T2  - Clinical Chemistry and Laboratory Medicine
T1  - Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy
VL  - 50
IS  - 11
SP  - 2019
EP  - 2025
DO  - 10.1515/cclm-2012-0117
ER  - 

@article{
author = "Stefanović, Aleksandra and Kotur-Stevuljević, Jelena and Vujović, Ana and Spasić, Slavica and Spasojević-Kalimanovska, Vesna and Jelić-Ivanović, Zorana and Martinović, Jelena and Ardalić, Daniela and Mandić-Marković, Vesna and Miković, Željko and Cerović, Nikola",
year = "2012",
abstract = "Background: Pregnancy is a stressful condition linked with altered lipid profile, increased oxidative stress and increased inflammation processes. The purpose of the present study was to determine the associations between those alterations with increased weight gain during pregnancy. Methods: The atherogenic index of plasma (AIP) and oxidative stress status parameters were determinated in 50 healthy and 172 pregnant women with non-complicated pregnancy. Pregnant women were divided in four groups according to body mass index (BMI) values (BMI quartiles). Results: Oxidative stress parameters were significantly lower in the control group compared with all the pregnant women quartiles. Unexpectedly, differences in oxidative stress parameters between BMI quartiles groups were not significant. The antioxidant defence parameters remained quite similar in the different BMI quartiles. Weight gain and paraoxonase-1 (PON1) activities were independently associated with increased AIP while weight gain and triglyceride concentration were found to be significant predictors of PON1 activities. Conclusions: The results of our current study indicate the association of maternal weight gain during pregnancy and altered lipid profile, elevated oxidative stress and changed antioxidative capacity of PON1. Taken together all these facts indicate possible increased risk of cardiovascular disease (CVD) development in later life if the weight gain during pregnancy is excessive.",
publisher = "Walter de Gruyter Gmbh, Berlin",
journal = "Clinical Chemistry and Laboratory Medicine",
title = "Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy",
volume = "50",
number = "11",
pages = "2019-2025",
doi = "10.1515/cclm-2012-0117"
}

Stefanović, A., Kotur-Stevuljević, J., Vujović, A., Spasić, S., Spasojević-Kalimanovska, V., Jelić-Ivanović, Z., Martinović, J., Ardalić, D., Mandić-Marković, V., Miković, Ž.,& Cerović, N.. (2012). Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy. in Clinical Chemistry and Laboratory Medicine
Walter de Gruyter Gmbh, Berlin., 50(11), 2019-2025.
https://doi.org/10.1515/cclm-2012-0117

Stefanović A, Kotur-Stevuljević J, Vujović A, Spasić S, Spasojević-Kalimanovska V, Jelić-Ivanović Z, Martinović J, Ardalić D, Mandić-Marković V, Miković Ž, Cerović N. Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy. in Clinical Chemistry and Laboratory Medicine. 2012;50(11):2019-2025.
doi:10.1515/cclm-2012-0117 .

Stefanović, Aleksandra, Kotur-Stevuljević, Jelena, Vujović, Ana, Spasić, Slavica, Spasojević-Kalimanovska, Vesna, Jelić-Ivanović, Zorana, Martinović, Jelena, Ardalić, Daniela, Mandić-Marković, Vesna, Miković, Željko, Cerović, Nikola, "Association of the atherogenic index of plasma and oxidative stress status with weight gain during non-complicated pregnancy" in Clinical Chemistry and Laboratory Medicine, 50, no. 11 (2012):2019-2025,
https://doi.org/10.1515/cclm-2012-0117 . .

TY  - JOUR
AU  - Martinović, Jelena
AU  - Dopsaj, Violeta
AU  - Kotur-Stevuljević, Jelena
AU  - Dopsaj, Milivoj
AU  - Vujović, Ana
AU  - Stefanović, Aleksandra
AU  - Nesić, Goran
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1525
AB  - Martinovic, J, Dopsaj, V, Kotur-Stevuljevic, J, Dopsaj, M, Vujovic, A, Stefanovic, A, and Nesic, G. Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period. J Strength Cond Res 25(5): 1360-1367, 2011-The objectives of this study were to determine (a) if reactive oxygen metabolites (ROMs) are a reliable parameter for monitoring oxidative stress in athletes alone or in association with other parameters of oxidative stress and depending on whether antioxidant supplements are taken or not; (b) the level of oxidative stress in athletes before the competition season; and
PB  - Lippincott Williams & Wilkins, Philadelphia
T2  - Journal of Strength and Conditioning Research
T1  - Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period
VL  - 25
IS  - 5
SP  - 1360
EP  - 1367
DO  - 10.1519/JSC.0b013e3181d85a7f
ER  - 

@article{
author = "Martinović, Jelena and Dopsaj, Violeta and Kotur-Stevuljević, Jelena and Dopsaj, Milivoj and Vujović, Ana and Stefanović, Aleksandra and Nesić, Goran",
year = "2011",
abstract = "Martinovic, J, Dopsaj, V, Kotur-Stevuljevic, J, Dopsaj, M, Vujovic, A, Stefanovic, A, and Nesic, G. Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period. J Strength Cond Res 25(5): 1360-1367, 2011-The objectives of this study were to determine (a) if reactive oxygen metabolites (ROMs) are a reliable parameter for monitoring oxidative stress in athletes alone or in association with other parameters of oxidative stress and depending on whether antioxidant supplements are taken or not; (b) the level of oxidative stress in athletes before the competition season; and",
publisher = "Lippincott Williams & Wilkins, Philadelphia",
journal = "Journal of Strength and Conditioning Research",
title = "Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period",
volume = "25",
number = "5",
pages = "1360-1367",
doi = "10.1519/JSC.0b013e3181d85a7f"
}

Martinović, J., Dopsaj, V., Kotur-Stevuljević, J., Dopsaj, M., Vujović, A., Stefanović, A.,& Nesić, G.. (2011). Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period. in Journal of Strength and Conditioning Research
Lippincott Williams & Wilkins, Philadelphia., 25(5), 1360-1367.
https://doi.org/10.1519/JSC.0b013e3181d85a7f

Martinović J, Dopsaj V, Kotur-Stevuljević J, Dopsaj M, Vujović A, Stefanović A, Nesić G. Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period. in Journal of Strength and Conditioning Research. 2011;25(5):1360-1367.
doi:10.1519/JSC.0b013e3181d85a7f .

Martinović, Jelena, Dopsaj, Violeta, Kotur-Stevuljević, Jelena, Dopsaj, Milivoj, Vujović, Ana, Stefanović, Aleksandra, Nesić, Goran, "Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period" in Journal of Strength and Conditioning Research, 25, no. 5 (2011):1360-1367,
https://doi.org/10.1519/JSC.0b013e3181d85a7f . .

TY  - JOUR
AU  - Martinović, J.
AU  - Dopsaj, Violeta
AU  - Kotur-Stevuljević, Jelena
AU  - Dopsaj, Milivoj
AU  - Vujović, Ana
AU  - Stefanović, Aleksandra
AU  - Nesić, G.
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1523
AB  - Aim. The objectives of this study were: 1) to evaluate pro-oxidant-antioxidant balance (PAB) associations with the commonly measured parameters of oxidative stress and antioxidative defence in elite female volleyball athletes; 2) to investigate changes in the parameters of oxidative stress during a period of intense training and dietary antioxidant supplementation. Methods. Twenty-seven female volleyball players participated in this study. Blood samples were collected the day before the pre-competitive mesocycle training period began. After the first blood sample donation and during the next six weeks fourteen players (supplemented group) received a cocktail of antioxidants while thirteen of them (control group) received no dietary supplementation. The following parameters were measured: reactive oxygen metabolites (ROMs), superoxide anion (O(2)(-)), malondialdehyde (AIDA), advanced oxidation protein products (AOPP), lipid hydroperoxides (LOOH), biological antioxidative potential (BAP), paraoxonase activity toward paraoxon (POase) and diazoxon (DZOase), superoxide dismutase (SOD), total sulphydryl group concentration (SH groups) and pro-oxidant-antioxidant balance. Results. Significant associations were observed between biomarkers of oxidative damage with PAB in multiple linear regression model in the supplemented and the control groups (82.3% vs. 83.1%) before training and in the control group (82.1%) after training. Significant associations between anti-oxidative defence parameters and PAB values were found in the supplemented group after six-weeks of training (57%). Conclusion. In the absence of antioxidant supplementation, PAB values were dependent on the association with biomarkers of oxidative damage before and after training. After a six-week training period and the applied antioxidant supplementation, PAB values were under the influence of nonenzymatic anti-oxidative defence.
PB  - Edizioni Minerva Medica, Turin
T2  - Journal of Sports Medicine and Physical Fitness
T1  - Proxidant antioxidant balance in supplemented elite female volleyball athletes during a six week training period
VL  - 51
IS  - 1
SP  - 145
EP  - 152
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1523
ER  - 

@article{
author = "Martinović, J. and Dopsaj, Violeta and Kotur-Stevuljević, Jelena and Dopsaj, Milivoj and Vujović, Ana and Stefanović, Aleksandra and Nesić, G.",
year = "2011",
abstract = "Aim. The objectives of this study were: 1) to evaluate pro-oxidant-antioxidant balance (PAB) associations with the commonly measured parameters of oxidative stress and antioxidative defence in elite female volleyball athletes; 2) to investigate changes in the parameters of oxidative stress during a period of intense training and dietary antioxidant supplementation. Methods. Twenty-seven female volleyball players participated in this study. Blood samples were collected the day before the pre-competitive mesocycle training period began. After the first blood sample donation and during the next six weeks fourteen players (supplemented group) received a cocktail of antioxidants while thirteen of them (control group) received no dietary supplementation. The following parameters were measured: reactive oxygen metabolites (ROMs), superoxide anion (O(2)(-)), malondialdehyde (AIDA), advanced oxidation protein products (AOPP), lipid hydroperoxides (LOOH), biological antioxidative potential (BAP), paraoxonase activity toward paraoxon (POase) and diazoxon (DZOase), superoxide dismutase (SOD), total sulphydryl group concentration (SH groups) and pro-oxidant-antioxidant balance. Results. Significant associations were observed between biomarkers of oxidative damage with PAB in multiple linear regression model in the supplemented and the control groups (82.3% vs. 83.1%) before training and in the control group (82.1%) after training. Significant associations between anti-oxidative defence parameters and PAB values were found in the supplemented group after six-weeks of training (57%). Conclusion. In the absence of antioxidant supplementation, PAB values were dependent on the association with biomarkers of oxidative damage before and after training. After a six-week training period and the applied antioxidant supplementation, PAB values were under the influence of nonenzymatic anti-oxidative defence.",
publisher = "Edizioni Minerva Medica, Turin",
journal = "Journal of Sports Medicine and Physical Fitness",
title = "Proxidant antioxidant balance in supplemented elite female volleyball athletes during a six week training period",
volume = "51",
number = "1",
pages = "145-152",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1523"
}

Martinović, J., Dopsaj, V., Kotur-Stevuljević, J., Dopsaj, M., Vujović, A., Stefanović, A.,& Nesić, G.. (2011). Proxidant antioxidant balance in supplemented elite female volleyball athletes during a six week training period. in Journal of Sports Medicine and Physical Fitness
Edizioni Minerva Medica, Turin., 51(1), 145-152.
https://hdl.handle.net/21.15107/rcub_farfar_1523

Martinović J, Dopsaj V, Kotur-Stevuljević J, Dopsaj M, Vujović A, Stefanović A, Nesić G. Proxidant antioxidant balance in supplemented elite female volleyball athletes during a six week training period. in Journal of Sports Medicine and Physical Fitness. 2011;51(1):145-152.
https://hdl.handle.net/21.15107/rcub_farfar_1523 .

Martinović, J., Dopsaj, Violeta, Kotur-Stevuljević, Jelena, Dopsaj, Milivoj, Vujović, Ana, Stefanović, Aleksandra, Nesić, G., "Proxidant antioxidant balance in supplemented elite female volleyball athletes during a six week training period" in Journal of Sports Medicine and Physical Fitness, 51, no. 1 (2011):145-152,
https://hdl.handle.net/21.15107/rcub_farfar_1523 .

TY  - CONF
AU  - Vujović, Ana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Bogavac-Stanojević, Nataša
AU  - Spasić, Slavica
AU  - Kotur-Stevuljević, Jelena
AU  - Jelić-Ivanović, Zorana
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1459
PB  - Elsevier Science BV, Amsterdam
C3  - European Journal of Pharmaceutical Sciences
T1  - A comparison of two RNA isolation methods to determine sod1 and sod2 gene expression in human blood and mononuclear cells
VL  - 44
IS  - Supplement 1
SP  - 195
EP  - 195
DO  - 10.1016/j.ejps.2011.08.002
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1459
ER  - 

@conference{
author = "Vujović, Ana and Spasojević-Kalimanovska, Vesna and Bogavac-Stanojević, Nataša and Spasić, Slavica and Kotur-Stevuljević, Jelena and Jelić-Ivanović, Zorana",
year = "2011",
publisher = "Elsevier Science BV, Amsterdam",
journal = "European Journal of Pharmaceutical Sciences",
title = "A comparison of two RNA isolation methods to determine sod1 and sod2 gene expression in human blood and mononuclear cells",
volume = "44",
number = "Supplement 1",
pages = "195-195",
doi = "10.1016/j.ejps.2011.08.002",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1459"
}

Vujović, A., Spasojević-Kalimanovska, V., Bogavac-Stanojević, N., Spasić, S., Kotur-Stevuljević, J.,& Jelić-Ivanović, Z.. (2011). A comparison of two RNA isolation methods to determine sod1 and sod2 gene expression in human blood and mononuclear cells. in European Journal of Pharmaceutical Sciences
Elsevier Science BV, Amsterdam., 44(Supplement 1), 195-195.
https://doi.org/10.1016/j.ejps.2011.08.002
https://hdl.handle.net/21.15107/rcub_farfar_1459

Vujović A, Spasojević-Kalimanovska V, Bogavac-Stanojević N, Spasić S, Kotur-Stevuljević J, Jelić-Ivanović Z. A comparison of two RNA isolation methods to determine sod1 and sod2 gene expression in human blood and mononuclear cells. in European Journal of Pharmaceutical Sciences. 2011;44(Supplement 1):195-195.
doi:10.1016/j.ejps.2011.08.002
https://hdl.handle.net/21.15107/rcub_farfar_1459 .

Vujović, Ana, Spasojević-Kalimanovska, Vesna, Bogavac-Stanojević, Nataša, Spasić, Slavica, Kotur-Stevuljević, Jelena, Jelić-Ivanović, Zorana, "A comparison of two RNA isolation methods to determine sod1 and sod2 gene expression in human blood and mononuclear cells" in European Journal of Pharmaceutical Sciences, 44, no. Supplement 1 (2011):195-195,
https://doi.org/10.1016/j.ejps.2011.08.002 .,
https://hdl.handle.net/21.15107/rcub_farfar_1459 .

TY  - CONF
AU  - Spasić, S.
AU  - Kotur-Stevuljević, Jelena
AU  - Peco-Antić, Amira
AU  - Kostić, M.
AU  - Vasić, Dragan
AU  - Stefanović, Aleksandra
AU  - Vujović, Ana
AU  - Jelić-Ivanović, Zorana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Kornić, D.
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1486
PB  - Elsevier Ireland Ltd, Clare
C3  - Atherosclerosis Supplements
T1  - Hyperlipidemia and oxidative stress are the main determinants of intima-media thickness in children with chronic kidney disease
VL  - 12
IS  - 1
SP  - 22
EP  - 22
DO  - 10.1016/S1567-5688(11)70094-0
ER  - 

@conference{
author = "Spasić, S. and Kotur-Stevuljević, Jelena and Peco-Antić, Amira and Kostić, M. and Vasić, Dragan and Stefanović, Aleksandra and Vujović, Ana and Jelić-Ivanović, Zorana and Spasojević-Kalimanovska, Vesna and Kornić, D.",
year = "2011",
publisher = "Elsevier Ireland Ltd, Clare",
journal = "Atherosclerosis Supplements",
title = "Hyperlipidemia and oxidative stress are the main determinants of intima-media thickness in children with chronic kidney disease",
volume = "12",
number = "1",
pages = "22-22",
doi = "10.1016/S1567-5688(11)70094-0"
}

Spasić, S., Kotur-Stevuljević, J., Peco-Antić, A., Kostić, M., Vasić, D., Stefanović, A., Vujović, A., Jelić-Ivanović, Z., Spasojević-Kalimanovska, V.,& Kornić, D.. (2011). Hyperlipidemia and oxidative stress are the main determinants of intima-media thickness in children with chronic kidney disease. in Atherosclerosis Supplements
Elsevier Ireland Ltd, Clare., 12(1), 22-22.
https://doi.org/10.1016/S1567-5688(11)70094-0

Spasić S, Kotur-Stevuljević J, Peco-Antić A, Kostić M, Vasić D, Stefanović A, Vujović A, Jelić-Ivanović Z, Spasojević-Kalimanovska V, Kornić D. Hyperlipidemia and oxidative stress are the main determinants of intima-media thickness in children with chronic kidney disease. in Atherosclerosis Supplements. 2011;12(1):22-22.
doi:10.1016/S1567-5688(11)70094-0 .

Spasić, S., Kotur-Stevuljević, Jelena, Peco-Antić, Amira, Kostić, M., Vasić, Dragan, Stefanović, Aleksandra, Vujović, Ana, Jelić-Ivanović, Zorana, Spasojević-Kalimanovska, Vesna, Kornić, D., "Hyperlipidemia and oxidative stress are the main determinants of intima-media thickness in children with chronic kidney disease" in Atherosclerosis Supplements, 12, no. 1 (2011):22-22,
https://doi.org/10.1016/S1567-5688(11)70094-0 . .

TY  - JOUR
AU  - Martinović, Jelena
AU  - Dopsaj, Violeta
AU  - Kotur-Stevuljević, Jelena
AU  - Dopsaj, Milivoj
AU  - Stefanović, Aleksandra
AU  - Kasum, Goran
AU  - Vujović, Ana
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1409
AB  - The main purpose of this study was to demonstrate the impact of different training regimes and the type of metabolism that predominates as the source of energy on the oxidative stress / anti-oxidative defense status in elite-level trained athletes. One hundred twenty-four athletes were divided into three groups: 'aerobic' (karate, rowing, triathlon), 'anaerobic' (wrestling and swimming) and 'mixed' (volleyball, water polo, kick boxing). The following parameters were measured: oxidative stress status parameters: [(reactive oxygen metabolites (ROMs), superoxide anion (O2 -), malondialdehyde (MDA), advanced oxidation protein products (AOPP) and lipid hydroperoxides (LOOH)] and anti-oxidative defense parameters [biological anti-oxidative potential (BAP), superoxide-dismutase (SOD), sulphydryl groups (-SH) and pro-oxidant-antioxidant balance (PAB)]. In general, significant differences were found in oxidative stress parameters between three experimental groups (Wilks' Lambda = 0.366, F value = 8.185, p  lt  0.001). Comparing the athletes from the anaerobic and mixed groups, we found that the anaerobic group had significantly lower ROMs (p = 0.019), AOPP (p  lt  0.001), O2 - (p = 0.003) and LOOH (p  lt  0.001). The aerobic group of athletes differed from the group with mixed training regime by lower AOPP, MDA, O2 - and LOOH values (p  lt  0.001). Discriminant analysis of the three experimental groups indicated protein oxidation marker (AOPP) and pro-oxidant-antioxidant balance as the most important discriminant variables. Oxidative stress status parameters adequately discriminated 74.2 % of the athletes with different energy expenditure during their training programs. The results obtained provide evidence that there are differences in the oxidative stress / anti-oxidant defense status between athletes that have different energy expenditure during exercise and identify athletes who participate in team sports as most susceptible to oxidative stress. .
PB  - Sportska akademija, Beograd
T2  - Serbian Journal of Sports sciences
T1  - Are oxidative stress and antioxidant defense status associated with energy expenditure in athletes of various sports?
VL  - 4
IS  - 1-4
SP  - 75
EP  - 81
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1409
ER  - 

@article{
author = "Martinović, Jelena and Dopsaj, Violeta and Kotur-Stevuljević, Jelena and Dopsaj, Milivoj and Stefanović, Aleksandra and Kasum, Goran and Vujović, Ana",
year = "2010",
abstract = "The main purpose of this study was to demonstrate the impact of different training regimes and the type of metabolism that predominates as the source of energy on the oxidative stress / anti-oxidative defense status in elite-level trained athletes. One hundred twenty-four athletes were divided into three groups: 'aerobic' (karate, rowing, triathlon), 'anaerobic' (wrestling and swimming) and 'mixed' (volleyball, water polo, kick boxing). The following parameters were measured: oxidative stress status parameters: [(reactive oxygen metabolites (ROMs), superoxide anion (O2 -), malondialdehyde (MDA), advanced oxidation protein products (AOPP) and lipid hydroperoxides (LOOH)] and anti-oxidative defense parameters [biological anti-oxidative potential (BAP), superoxide-dismutase (SOD), sulphydryl groups (-SH) and pro-oxidant-antioxidant balance (PAB)]. In general, significant differences were found in oxidative stress parameters between three experimental groups (Wilks' Lambda = 0.366, F value = 8.185, p  lt  0.001). Comparing the athletes from the anaerobic and mixed groups, we found that the anaerobic group had significantly lower ROMs (p = 0.019), AOPP (p  lt  0.001), O2 - (p = 0.003) and LOOH (p  lt  0.001). The aerobic group of athletes differed from the group with mixed training regime by lower AOPP, MDA, O2 - and LOOH values (p  lt  0.001). Discriminant analysis of the three experimental groups indicated protein oxidation marker (AOPP) and pro-oxidant-antioxidant balance as the most important discriminant variables. Oxidative stress status parameters adequately discriminated 74.2 % of the athletes with different energy expenditure during their training programs. The results obtained provide evidence that there are differences in the oxidative stress / anti-oxidant defense status between athletes that have different energy expenditure during exercise and identify athletes who participate in team sports as most susceptible to oxidative stress. .",
publisher = "Sportska akademija, Beograd",
journal = "Serbian Journal of Sports sciences",
title = "Are oxidative stress and antioxidant defense status associated with energy expenditure in athletes of various sports?",
volume = "4",
number = "1-4",
pages = "75-81",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1409"
}

Martinović, J., Dopsaj, V., Kotur-Stevuljević, J., Dopsaj, M., Stefanović, A., Kasum, G.,& Vujović, A.. (2010). Are oxidative stress and antioxidant defense status associated with energy expenditure in athletes of various sports?. in Serbian Journal of Sports sciences
Sportska akademija, Beograd., 4(1-4), 75-81.
https://hdl.handle.net/21.15107/rcub_farfar_1409

Martinović J, Dopsaj V, Kotur-Stevuljević J, Dopsaj M, Stefanović A, Kasum G, Vujović A. Are oxidative stress and antioxidant defense status associated with energy expenditure in athletes of various sports?. in Serbian Journal of Sports sciences. 2010;4(1-4):75-81.
https://hdl.handle.net/21.15107/rcub_farfar_1409 .

Martinović, Jelena, Dopsaj, Violeta, Kotur-Stevuljević, Jelena, Dopsaj, Milivoj, Stefanović, Aleksandra, Kasum, Goran, Vujović, Ana, "Are oxidative stress and antioxidant defense status associated with energy expenditure in athletes of various sports?" in Serbian Journal of Sports sciences, 4, no. 1-4 (2010):75-81,
https://hdl.handle.net/21.15107/rcub_farfar_1409 .

TY  - JOUR
AU  - Vujović, Ana
AU  - Kotur-Stevuljević, Jelena
AU  - Kornić, D.
AU  - Spasojević-Kalimanovska, Vesna
AU  - Spasić, Slavica
AU  - Bogavac-Stanojević, Nataša
AU  - Stefanović, Aleksandra
AU  - Deanović, M.
AU  - Babka, Sofika
AU  - Aleksić, B.
AU  - Jelić-Ivanović, Zorana
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1377
AB  - Objective: To evaluate the possible relationship between industrial air pollution and oxidative stress in schoolchildren by comparing parameters from children residing in two nearby localities with contrasting environmental conditions. Participants: 42 schoolchildren (12-15 years) from Pancevo (site of Serbia's largest petrochemical installation) formed the exposed group. 82 schoolchildren from Kovacica village, located 30 km north of Pancevo, formed the non-exposed group. Methods: Oxidative stress status, anti-oxidative defense parameters, paraoxonase-1 status, lipid status, glucose concentration and leukocyte counts were compared in two groups. Results: The children from Pancevo showed higher level of oxidative stress demonstrated by an elevated malondialdehyde concentration (P  lt 0.001) and decreased superoxide dismutase activity (P lt 0.01) in comparison to the non-exposed group. Conclusions: The results suggested a relationship between the presence of air pollutants and increased oxidative stress in schoolchildren residing in an industrial environment.
PB  - Indian Acad Pediatrics, New Delhi
T2  - Indian Pediatrics
T1  - Oxidative Stress and Anti-oxidative Defense in Schoolchildren Residing in a Petrochemical Industry Environment
VL  - 47
IS  - 3
SP  - 233
EP  - 239
DO  - 10.1007/s13312-010-0045-y
ER  - 

@article{
author = "Vujović, Ana and Kotur-Stevuljević, Jelena and Kornić, D. and Spasojević-Kalimanovska, Vesna and Spasić, Slavica and Bogavac-Stanojević, Nataša and Stefanović, Aleksandra and Deanović, M. and Babka, Sofika and Aleksić, B. and Jelić-Ivanović, Zorana",
year = "2010",
abstract = "Objective: To evaluate the possible relationship between industrial air pollution and oxidative stress in schoolchildren by comparing parameters from children residing in two nearby localities with contrasting environmental conditions. Participants: 42 schoolchildren (12-15 years) from Pancevo (site of Serbia's largest petrochemical installation) formed the exposed group. 82 schoolchildren from Kovacica village, located 30 km north of Pancevo, formed the non-exposed group. Methods: Oxidative stress status, anti-oxidative defense parameters, paraoxonase-1 status, lipid status, glucose concentration and leukocyte counts were compared in two groups. Results: The children from Pancevo showed higher level of oxidative stress demonstrated by an elevated malondialdehyde concentration (P  lt 0.001) and decreased superoxide dismutase activity (P lt 0.01) in comparison to the non-exposed group. Conclusions: The results suggested a relationship between the presence of air pollutants and increased oxidative stress in schoolchildren residing in an industrial environment.",
publisher = "Indian Acad Pediatrics, New Delhi",
journal = "Indian Pediatrics",
title = "Oxidative Stress and Anti-oxidative Defense in Schoolchildren Residing in a Petrochemical Industry Environment",
volume = "47",
number = "3",
pages = "233-239",
doi = "10.1007/s13312-010-0045-y"
}

Vujović, A., Kotur-Stevuljević, J., Kornić, D., Spasojević-Kalimanovska, V., Spasić, S., Bogavac-Stanojević, N., Stefanović, A., Deanović, M., Babka, S., Aleksić, B.,& Jelić-Ivanović, Z.. (2010). Oxidative Stress and Anti-oxidative Defense in Schoolchildren Residing in a Petrochemical Industry Environment. in Indian Pediatrics
Indian Acad Pediatrics, New Delhi., 47(3), 233-239.
https://doi.org/10.1007/s13312-010-0045-y

Vujović A, Kotur-Stevuljević J, Kornić D, Spasojević-Kalimanovska V, Spasić S, Bogavac-Stanojević N, Stefanović A, Deanović M, Babka S, Aleksić B, Jelić-Ivanović Z. Oxidative Stress and Anti-oxidative Defense in Schoolchildren Residing in a Petrochemical Industry Environment. in Indian Pediatrics. 2010;47(3):233-239.
doi:10.1007/s13312-010-0045-y .

Vujović, Ana, Kotur-Stevuljević, Jelena, Kornić, D., Spasojević-Kalimanovska, Vesna, Spasić, Slavica, Bogavac-Stanojević, Nataša, Stefanović, Aleksandra, Deanović, M., Babka, Sofika, Aleksić, B., Jelić-Ivanović, Zorana, "Oxidative Stress and Anti-oxidative Defense in Schoolchildren Residing in a Petrochemical Industry Environment" in Indian Pediatrics, 47, no. 3 (2010):233-239,
https://doi.org/10.1007/s13312-010-0045-y . .

TY  - JOUR
AU  - Vujović, Ana
AU  - Kotur-Stevuljević, Jelena
AU  - Spasić, Slavica
AU  - Bujisić, Nada
AU  - Martinović, Jelena
AU  - Vujović, Milica
AU  - Spasojević-Kalimanovska, Vesna
AU  - Zeljković, Aleksandra
AU  - Pajić, Dragoljub
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1374
AB  - Background: Friedewald's formula for the estimation of LDL-C concentration is the most often used formula in clinical practice. A recent formula by Anandaraja and colleagues for LDL-C estimation still needs to be evaluated before it is extensively applied in diagnosis. In the present study we validated existing formulas and derived a more accurate formula to determine LDL-C in a Serbian population. Methods: Our study included 2053 patients with TG  lt = 4.52 mmol/L. In an initial group of 1010 patients, Friedewald's and Anandaraja's formulas were compared to a direct homogenous method for LDL-C determination. The obtained results allowed us to modify Friedewald's formula and apply it in a second group of patients. Results: The mean LDL-C concentrations were 3.9 +/- 1.09 mmol/L, 3.63 +/- 1.06 mmol/L and 3.72 +/- 1.04 mmol/L measured by a direct homogenous assay (D-LDL-C), calculated by Friedewald's formula (F-LDL-C) and calculated by Anandaraja's formula (A-LDL-C), respectively in the 1010 patients. The Student's paired t-test showed that D-LDL-C values were significantly higher than F-LDL-C and A-LDL-C values (p  lt  0.001). The Passing-Bablok regression analysis indicated good correlation between calculated and measured LDL-Cs (r > 0.89). Using lipoprotein values from the initial group we modified Friedewald's formula by replacing the term 2.2 with 3. The new modified formula for LDL-C estimation (S-LDL-C) showed no statistically significant difference compared to D-LDL-C. The absolute bias between these two methods was -0.06 +/- 0.37 mmol/L with a high correlation coefficient (r = 0.96). Conclusions: Our modified formula for LDL-C estimation appears to be more accurate than both Friedewald's and Anandaraja's formulas when applied to a Serbian population.
PB  - BMC, LONDON
T2  - Lipids in Health and Disease
T1  - Evaluation of different formulas for LDL-C calculation
VL  - 9
DO  - 10.1186/1476-511X-9-27
ER  - 

@article{
author = "Vujović, Ana and Kotur-Stevuljević, Jelena and Spasić, Slavica and Bujisić, Nada and Martinović, Jelena and Vujović, Milica and Spasojević-Kalimanovska, Vesna and Zeljković, Aleksandra and Pajić, Dragoljub",
year = "2010",
abstract = "Background: Friedewald's formula for the estimation of LDL-C concentration is the most often used formula in clinical practice. A recent formula by Anandaraja and colleagues for LDL-C estimation still needs to be evaluated before it is extensively applied in diagnosis. In the present study we validated existing formulas and derived a more accurate formula to determine LDL-C in a Serbian population. Methods: Our study included 2053 patients with TG  lt = 4.52 mmol/L. In an initial group of 1010 patients, Friedewald's and Anandaraja's formulas were compared to a direct homogenous method for LDL-C determination. The obtained results allowed us to modify Friedewald's formula and apply it in a second group of patients. Results: The mean LDL-C concentrations were 3.9 +/- 1.09 mmol/L, 3.63 +/- 1.06 mmol/L and 3.72 +/- 1.04 mmol/L measured by a direct homogenous assay (D-LDL-C), calculated by Friedewald's formula (F-LDL-C) and calculated by Anandaraja's formula (A-LDL-C), respectively in the 1010 patients. The Student's paired t-test showed that D-LDL-C values were significantly higher than F-LDL-C and A-LDL-C values (p  lt  0.001). The Passing-Bablok regression analysis indicated good correlation between calculated and measured LDL-Cs (r > 0.89). Using lipoprotein values from the initial group we modified Friedewald's formula by replacing the term 2.2 with 3. The new modified formula for LDL-C estimation (S-LDL-C) showed no statistically significant difference compared to D-LDL-C. The absolute bias between these two methods was -0.06 +/- 0.37 mmol/L with a high correlation coefficient (r = 0.96). Conclusions: Our modified formula for LDL-C estimation appears to be more accurate than both Friedewald's and Anandaraja's formulas when applied to a Serbian population.",
publisher = "BMC, LONDON",
journal = "Lipids in Health and Disease",
title = "Evaluation of different formulas for LDL-C calculation",
volume = "9",
doi = "10.1186/1476-511X-9-27"
}

Vujović, A., Kotur-Stevuljević, J., Spasić, S., Bujisić, N., Martinović, J., Vujović, M., Spasojević-Kalimanovska, V., Zeljković, A.,& Pajić, D.. (2010). Evaluation of different formulas for LDL-C calculation. in Lipids in Health and Disease
BMC, LONDON., 9.
https://doi.org/10.1186/1476-511X-9-27

Vujović A, Kotur-Stevuljević J, Spasić S, Bujisić N, Martinović J, Vujović M, Spasojević-Kalimanovska V, Zeljković A, Pajić D. Evaluation of different formulas for LDL-C calculation. in Lipids in Health and Disease. 2010;9.
doi:10.1186/1476-511X-9-27 .

Vujović, Ana, Kotur-Stevuljević, Jelena, Spasić, Slavica, Bujisić, Nada, Martinović, Jelena, Vujović, Milica, Spasojević-Kalimanovska, Vesna, Zeljković, Aleksandra, Pajić, Dragoljub, "Evaluation of different formulas for LDL-C calculation" in Lipids in Health and Disease, 9 (2010),
https://doi.org/10.1186/1476-511X-9-27 . .

TY  - JOUR
AU  - Martinović, J.
AU  - Dopsaj, Violeta
AU  - Dopsaj, Milivoj
AU  - Kotur-Stevuljević, Jelena
AU  - Vujović, Ana
AU  - Stefanović, Aleksandra
AU  - Nesić, G.
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1213
AB  - The aim of this study was to determine the impact of long-term training on elite female volleyball players and to determine parameters that could discriminate them according to the level of oxidative stress-associated adaptation. Fifty-four elite female volleyball players were divided into 3 groups (1: below-average training experience  lt 8.0 years, 2: average training experience between 8.0 and 10.5 years and 3: above-average training experience > 10.5 years). The measured parameters were reactive oxygen metabolites, biological anti-oxidative potential, superoxide anion, malondialdehyde, advanced oxidation protein products, lipid hydroperoxides, paraoxonase activity, superoxide-dismutase activity and sulphydryl groups. Multiple discriminant analysis of the oxidative stress status parameters between the three groups of athletes indicated a statistically significant difference (Wilks' lambda=0.458, X-2=35.898, p=0.031). The most important discriminant variables, superoxide-dismutase and superoxide anion, were the best indicators of differences between groups with different training experience. The significantly higher values were found in Group 3 compared with Group 1 in superoxide-dismutase activity (141 +/- 32 vs. 86 +/- 46; p=0.002), sulphydryl groups (p=0.031), and reactive oxygen metabolites (p = 0.042). The significantly lower superoxide anion was found between Group 3 and Group 1 (377 +/- 187 vs. 1183 +/- 905; p=0.001). Oxidative stress status parameters adequately discriminated 68.5% of athletes with different training experience.
PB  - Georg Thieme Verlag Kg, Stuttgart
T2  - International Journal of Sports Medicine
T1  - Long-term Effects of Oxidative Stress in Volleyball Players
VL  - 30
IS  - 12
SP  - 851
EP  - 856
DO  - 10.1055/s-0029-1238289
ER  - 

@article{
author = "Martinović, J. and Dopsaj, Violeta and Dopsaj, Milivoj and Kotur-Stevuljević, Jelena and Vujović, Ana and Stefanović, Aleksandra and Nesić, G.",
year = "2009",
abstract = "The aim of this study was to determine the impact of long-term training on elite female volleyball players and to determine parameters that could discriminate them according to the level of oxidative stress-associated adaptation. Fifty-four elite female volleyball players were divided into 3 groups (1: below-average training experience  lt 8.0 years, 2: average training experience between 8.0 and 10.5 years and 3: above-average training experience > 10.5 years). The measured parameters were reactive oxygen metabolites, biological anti-oxidative potential, superoxide anion, malondialdehyde, advanced oxidation protein products, lipid hydroperoxides, paraoxonase activity, superoxide-dismutase activity and sulphydryl groups. Multiple discriminant analysis of the oxidative stress status parameters between the three groups of athletes indicated a statistically significant difference (Wilks' lambda=0.458, X-2=35.898, p=0.031). The most important discriminant variables, superoxide-dismutase and superoxide anion, were the best indicators of differences between groups with different training experience. The significantly higher values were found in Group 3 compared with Group 1 in superoxide-dismutase activity (141 +/- 32 vs. 86 +/- 46; p=0.002), sulphydryl groups (p=0.031), and reactive oxygen metabolites (p = 0.042). The significantly lower superoxide anion was found between Group 3 and Group 1 (377 +/- 187 vs. 1183 +/- 905; p=0.001). Oxidative stress status parameters adequately discriminated 68.5% of athletes with different training experience.",
publisher = "Georg Thieme Verlag Kg, Stuttgart",
journal = "International Journal of Sports Medicine",
title = "Long-term Effects of Oxidative Stress in Volleyball Players",
volume = "30",
number = "12",
pages = "851-856",
doi = "10.1055/s-0029-1238289"
}

Martinović, J., Dopsaj, V., Dopsaj, M., Kotur-Stevuljević, J., Vujović, A., Stefanović, A.,& Nesić, G.. (2009). Long-term Effects of Oxidative Stress in Volleyball Players. in International Journal of Sports Medicine
Georg Thieme Verlag Kg, Stuttgart., 30(12), 851-856.
https://doi.org/10.1055/s-0029-1238289

Martinović J, Dopsaj V, Dopsaj M, Kotur-Stevuljević J, Vujović A, Stefanović A, Nesić G. Long-term Effects of Oxidative Stress in Volleyball Players. in International Journal of Sports Medicine. 2009;30(12):851-856.
doi:10.1055/s-0029-1238289 .

Martinović, J., Dopsaj, Violeta, Dopsaj, Milivoj, Kotur-Stevuljević, Jelena, Vujović, Ana, Stefanović, Aleksandra, Nesić, G., "Long-term Effects of Oxidative Stress in Volleyball Players" in International Journal of Sports Medicine, 30, no. 12 (2009):851-856,
https://doi.org/10.1055/s-0029-1238289 . .

TY  - JOUR
AU  - Vekić, Jelena
AU  - Kotur-Stevuljević, Jelena
AU  - Zeljković, Aleksandra
AU  - Stefanović, Aleksandra
AU  - Bogavac-Stanojević, Nataša
AU  - Vujović, Ana
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1139
AB  - Oxidative stress is a result of an imbalanced equilibrium between reactive oxygen species (ROS) generation and their elimination by antioxidants. There is substantial evidence indicating that exacerbated oxidative stress is relevant for the development of atherosclerosis and its associated complications, especially cardiovascular disease (CVD). According to the oxidative modification hypothesis, oxidised low density lipoproteins (LDL) induce atherosclerosis by triggering an inflammatory cascade within the vascular wall. This process can be inhibited or delayed by the antioxidative and anti-inflammatory actions of high density lipoproteins (HDL). Clearly, paraoxonase-1 (PON1) is one of the most important contributors to the antioxidative capacity of HDL. Atherogenic dyslipidemia, oxidative stress and inflammatory conditions induce dramatic changes in HDL composition that considerably alters or attenuates HDL's anti-atherogenic effects. Such impairment of HDL's functions provides an important link between oxidative stress and inflammation in the pathogenesis of atherosclerosis. This review summarises and discusses the possible synergistic effects of dyslipidemia, oxidative stress and inflammation in promoting atherosclerosis and its complications, as well as potential benefits of therapeutic modulation of HDL's atheroprotective activity.
T2  - Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry
T1  - Oxidative stress, HDL and atherosclerosis
VL  - 7
IS  - 3
SP  - 158
EP  - 165
DO  - 10.2174/187152308785699281
ER  - 

@article{
author = "Vekić, Jelena and Kotur-Stevuljević, Jelena and Zeljković, Aleksandra and Stefanović, Aleksandra and Bogavac-Stanojević, Nataša and Vujović, Ana",
year = "2008",
abstract = "Oxidative stress is a result of an imbalanced equilibrium between reactive oxygen species (ROS) generation and their elimination by antioxidants. There is substantial evidence indicating that exacerbated oxidative stress is relevant for the development of atherosclerosis and its associated complications, especially cardiovascular disease (CVD). According to the oxidative modification hypothesis, oxidised low density lipoproteins (LDL) induce atherosclerosis by triggering an inflammatory cascade within the vascular wall. This process can be inhibited or delayed by the antioxidative and anti-inflammatory actions of high density lipoproteins (HDL). Clearly, paraoxonase-1 (PON1) is one of the most important contributors to the antioxidative capacity of HDL. Atherogenic dyslipidemia, oxidative stress and inflammatory conditions induce dramatic changes in HDL composition that considerably alters or attenuates HDL's anti-atherogenic effects. Such impairment of HDL's functions provides an important link between oxidative stress and inflammation in the pathogenesis of atherosclerosis. This review summarises and discusses the possible synergistic effects of dyslipidemia, oxidative stress and inflammation in promoting atherosclerosis and its complications, as well as potential benefits of therapeutic modulation of HDL's atheroprotective activity.",
journal = "Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry",
title = "Oxidative stress, HDL and atherosclerosis",
volume = "7",
number = "3",
pages = "158-165",
doi = "10.2174/187152308785699281"
}

Vekić, J., Kotur-Stevuljević, J., Zeljković, A., Stefanović, A., Bogavac-Stanojević, N.,& Vujović, A.. (2008). Oxidative stress, HDL and atherosclerosis. in Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry, 7(3), 158-165.
https://doi.org/10.2174/187152308785699281

Vekić J, Kotur-Stevuljević J, Zeljković A, Stefanović A, Bogavac-Stanojević N, Vujović A. Oxidative stress, HDL and atherosclerosis. in Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry. 2008;7(3):158-165.
doi:10.2174/187152308785699281 .

Vekić, Jelena, Kotur-Stevuljević, Jelena, Zeljković, Aleksandra, Stefanović, Aleksandra, Bogavac-Stanojević, Nataša, Vujović, Ana, "Oxidative stress, HDL and atherosclerosis" in Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry, 7, no. 3 (2008):158-165,
https://doi.org/10.2174/187152308785699281 . .

TY  - JOUR
AU  - Kotur-Stevuljević, Jelena
AU  - Spasić, Slavica
AU  - Jelić-Ivanović, Zorana
AU  - Spasojević-Kalimanovska, Vesna
AU  - Stefanović, Aleksandra
AU  - Vujović, Ana
AU  - Memon, Lidija
AU  - Kalimanovska-Oštrić, Dimitra
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1119
AB  - Objectives: High-density lipoprotein (HDL) associated paraoxonase. 1 (PON1) is an essential component of HDLs' capability to protect low-density lipoproteins (LDL) from oxidative modification and thus to limit the atherosclerotic process. The aim of the Current Study was to investigate the association between oxidative stress status, indices of inflammation and PON1 status parameters. Design and methods: We determined the relationship between the oxidative stress status, inflammatory markers and PON1 status parameters in 261 middle-aged subjects: 156 coronary heart disease (CHD) patients and 105 CHD-free subjects (as the control group). The PON1 status involved PON1 activity measurements towards two substrates: paraoxon (POase activity) and diazoxon (DZOase activity) and subsequent PON1(Q192R) activity phenotype determination. Results: A statistically significant greater malondialdehyde (MDA) concentration in the RR phenotype subjects compared to QQ subjects within the CHD group was apparent (P lt 0.05). Multiple linear regression analysis revealed an independent influence of plasmatic SOD activity (P lt 0.05) on POase values and MDA (P lt 0.01) and O-2(center dot-) (P lt 0.05) on DZOase values. Involvement of inflammatory markers (fibrinogen and hsCRP) in the regression model did not hinder the influence of SOD and MDA on POase and DZOase activities, respectively. Conclusions: Our CHD patients were in a state of oxidative stress, which was most evident in the RR phenotype group. The QQ phenotype group is associated with the lowest oxidative stress status level and also with a better capacity for anti-oxidative protection. Oxidative stress in CHD patients is maintained by systemic low-grade inflammation which results in PON1 enzymatic activity exhaustion. Therefore, deeper investigation of an effective anti-oxidative and anti-inflammatory therapy should be necessary in order to increase anti-oxidative potency and improve PON1 status of CHD patients.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Clinical Biochemistry
T1  - PON1 status is influenced by oxidative stress and inflammation in coronary heart disease patients
VL  - 41
IS  - 13
SP  - 1067
EP  - 1073
DO  - 10.1016/j.clinbiochem.2008.06.009
ER  - 

@article{
author = "Kotur-Stevuljević, Jelena and Spasić, Slavica and Jelić-Ivanović, Zorana and Spasojević-Kalimanovska, Vesna and Stefanović, Aleksandra and Vujović, Ana and Memon, Lidija and Kalimanovska-Oštrić, Dimitra",
year = "2008",
abstract = "Objectives: High-density lipoprotein (HDL) associated paraoxonase. 1 (PON1) is an essential component of HDLs' capability to protect low-density lipoproteins (LDL) from oxidative modification and thus to limit the atherosclerotic process. The aim of the Current Study was to investigate the association between oxidative stress status, indices of inflammation and PON1 status parameters. Design and methods: We determined the relationship between the oxidative stress status, inflammatory markers and PON1 status parameters in 261 middle-aged subjects: 156 coronary heart disease (CHD) patients and 105 CHD-free subjects (as the control group). The PON1 status involved PON1 activity measurements towards two substrates: paraoxon (POase activity) and diazoxon (DZOase activity) and subsequent PON1(Q192R) activity phenotype determination. Results: A statistically significant greater malondialdehyde (MDA) concentration in the RR phenotype subjects compared to QQ subjects within the CHD group was apparent (P lt 0.05). Multiple linear regression analysis revealed an independent influence of plasmatic SOD activity (P lt 0.05) on POase values and MDA (P lt 0.01) and O-2(center dot-) (P lt 0.05) on DZOase values. Involvement of inflammatory markers (fibrinogen and hsCRP) in the regression model did not hinder the influence of SOD and MDA on POase and DZOase activities, respectively. Conclusions: Our CHD patients were in a state of oxidative stress, which was most evident in the RR phenotype group. The QQ phenotype group is associated with the lowest oxidative stress status level and also with a better capacity for anti-oxidative protection. Oxidative stress in CHD patients is maintained by systemic low-grade inflammation which results in PON1 enzymatic activity exhaustion. Therefore, deeper investigation of an effective anti-oxidative and anti-inflammatory therapy should be necessary in order to increase anti-oxidative potency and improve PON1 status of CHD patients.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Clinical Biochemistry",
title = "PON1 status is influenced by oxidative stress and inflammation in coronary heart disease patients",
volume = "41",
number = "13",
pages = "1067-1073",
doi = "10.1016/j.clinbiochem.2008.06.009"
}

Kotur-Stevuljević, J., Spasić, S., Jelić-Ivanović, Z., Spasojević-Kalimanovska, V., Stefanović, A., Vujović, A., Memon, L.,& Kalimanovska-Oštrić, D.. (2008). PON1 status is influenced by oxidative stress and inflammation in coronary heart disease patients. in Clinical Biochemistry
Pergamon-Elsevier Science Ltd, Oxford., 41(13), 1067-1073.
https://doi.org/10.1016/j.clinbiochem.2008.06.009

Kotur-Stevuljević J, Spasić S, Jelić-Ivanović Z, Spasojević-Kalimanovska V, Stefanović A, Vujović A, Memon L, Kalimanovska-Oštrić D. PON1 status is influenced by oxidative stress and inflammation in coronary heart disease patients. in Clinical Biochemistry. 2008;41(13):1067-1073.
doi:10.1016/j.clinbiochem.2008.06.009 .

Kotur-Stevuljević, Jelena, Spasić, Slavica, Jelić-Ivanović, Zorana, Spasojević-Kalimanovska, Vesna, Stefanović, Aleksandra, Vujović, Ana, Memon, Lidija, Kalimanovska-Oštrić, Dimitra, "PON1 status is influenced by oxidative stress and inflammation in coronary heart disease patients" in Clinical Biochemistry, 41, no. 13 (2008):1067-1073,
https://doi.org/10.1016/j.clinbiochem.2008.06.009 . .

TY  - JOUR
AU  - Zeljković, Aleksandra
AU  - Spasojević-Kalimanovska, Vesna
AU  - Vekić, Jelena
AU  - Jelić-Ivanović, Zorana
AU  - Topić, Aleksandra
AU  - Bogavac-Stanojević, Nataša
AU  - Spasić, Slavica
AU  - Vujović, Ana
AU  - Kalimanovska-Oštrić, Dimitra
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1082
AB  - Background Alterations in plasma lipoprotein subclass distribution affect the risk for coronary artery disease (CAD). However, it is unclear whether the determination of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) phenotypes may or may not improve the ability to predict CAD development. Methods Polyacrylamide gradient (3-31%) gel electrophoresis was used to simultaneously determine size and distribution of lipoprotein subclasses in 181 CAD patients and 178 controls. Results Mean LDL and HDL subclass sizes were significantly smaller in patients than in controls (p  lt  0.001). Multivariate logistic regression analysis showed that small dense LDL particles were independent CAD risk predictors (OR = 2.867, p  lt  0.01), even when adjusted for other traditional risk factors, while small HDL particles lost their significance after adjustment (OR = 2.071, p = 0.054). The area under the ROC curve for LDL (0.671) and HDL (0.643) particle size measurement demonstrated low clinical accuracy when compared to the combination of traditional lipid risk factor measurements. Conclusions CAD is associated with the predominance of smaller LDL and HDL particles. However, simultaneous determination of these two lipoprotein phenotypes provides no additional power in discriminating CAD and non-CAD subjects, beyond that obtained by the traditional risk factors.
PB  - Springer, New York
T2  - Clinical and Experimental Medicine
T1  - Does simultaneous determination of LDL and HDL particle size improve prediction of coronary artery disease risk?
VL  - 8
IS  - 2
SP  - 109
EP  - 116
DO  - 10.1007/s10238-008-0165-z
ER  - 

@article{
author = "Zeljković, Aleksandra and Spasojević-Kalimanovska, Vesna and Vekić, Jelena and Jelić-Ivanović, Zorana and Topić, Aleksandra and Bogavac-Stanojević, Nataša and Spasić, Slavica and Vujović, Ana and Kalimanovska-Oštrić, Dimitra",
year = "2008",
abstract = "Background Alterations in plasma lipoprotein subclass distribution affect the risk for coronary artery disease (CAD). However, it is unclear whether the determination of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) phenotypes may or may not improve the ability to predict CAD development. Methods Polyacrylamide gradient (3-31%) gel electrophoresis was used to simultaneously determine size and distribution of lipoprotein subclasses in 181 CAD patients and 178 controls. Results Mean LDL and HDL subclass sizes were significantly smaller in patients than in controls (p  lt  0.001). Multivariate logistic regression analysis showed that small dense LDL particles were independent CAD risk predictors (OR = 2.867, p  lt  0.01), even when adjusted for other traditional risk factors, while small HDL particles lost their significance after adjustment (OR = 2.071, p = 0.054). The area under the ROC curve for LDL (0.671) and HDL (0.643) particle size measurement demonstrated low clinical accuracy when compared to the combination of traditional lipid risk factor measurements. Conclusions CAD is associated with the predominance of smaller LDL and HDL particles. However, simultaneous determination of these two lipoprotein phenotypes provides no additional power in discriminating CAD and non-CAD subjects, beyond that obtained by the traditional risk factors.",
publisher = "Springer, New York",
journal = "Clinical and Experimental Medicine",
title = "Does simultaneous determination of LDL and HDL particle size improve prediction of coronary artery disease risk?",
volume = "8",
number = "2",
pages = "109-116",
doi = "10.1007/s10238-008-0165-z"
}

Zeljković, A., Spasojević-Kalimanovska, V., Vekić, J., Jelić-Ivanović, Z., Topić, A., Bogavac-Stanojević, N., Spasić, S., Vujović, A.,& Kalimanovska-Oštrić, D.. (2008). Does simultaneous determination of LDL and HDL particle size improve prediction of coronary artery disease risk?. in Clinical and Experimental Medicine
Springer, New York., 8(2), 109-116.
https://doi.org/10.1007/s10238-008-0165-z

Zeljković A, Spasojević-Kalimanovska V, Vekić J, Jelić-Ivanović Z, Topić A, Bogavac-Stanojević N, Spasić S, Vujović A, Kalimanovska-Oštrić D. Does simultaneous determination of LDL and HDL particle size improve prediction of coronary artery disease risk?. in Clinical and Experimental Medicine. 2008;8(2):109-116.
doi:10.1007/s10238-008-0165-z .

Zeljković, Aleksandra, Spasojević-Kalimanovska, Vesna, Vekić, Jelena, Jelić-Ivanović, Zorana, Topić, Aleksandra, Bogavac-Stanojević, Nataša, Spasić, Slavica, Vujović, Ana, Kalimanovska-Oštrić, Dimitra, "Does simultaneous determination of LDL and HDL particle size improve prediction of coronary artery disease risk?" in Clinical and Experimental Medicine, 8, no. 2 (2008):109-116,
https://doi.org/10.1007/s10238-008-0165-z . .