TY  - CONF
AU  - Ristić, Aleksandra
AU  - Ružić, Tijana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4777
AB  - Трава ива, Teucrium montanum L. (Lamiaceae) је вишегодишња биљка богата полифенолним једињењима.
AB  - The mountain germander, Teucrium montanum L. (Lamiaceae) is a perennial plant rich in polyphenolic compounds.
T1  - Испитивање антиоксидативне и генотоксичне активност екстракта Teucrium montanum L.
T1  - Examination of antioxidant and genotoxic activity of Teucrium montanum L. extract
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4777
ER  - 

@conference{
author = "Ristić, Aleksandra and Ružić, Tijana",
year = "2023",
abstract = "Трава ива, Teucrium montanum L. (Lamiaceae) је вишегодишња биљка богата полифенолним једињењима., The mountain germander, Teucrium montanum L. (Lamiaceae) is a perennial plant rich in polyphenolic compounds.",
title = "Испитивање антиоксидативне и генотоксичне активност екстракта Teucrium montanum L., Examination of antioxidant and genotoxic activity of Teucrium montanum L. extract",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4777"
}

Ristić, A.,& Ružić, T.. (2023). Испитивање антиоксидативне и генотоксичне активност екстракта Teucrium montanum L.. .
https://hdl.handle.net/21.15107/rcub_farfar_4777

Ristić A, Ružić T. Испитивање антиоксидативне и генотоксичне активност екстракта Teucrium montanum L.. 2023;.
https://hdl.handle.net/21.15107/rcub_farfar_4777 .

Ristić, Aleksandra, Ružić, Tijana, "Испитивање антиоксидативне и генотоксичне активност екстракта Teucrium montanum L." (2023),
https://hdl.handle.net/21.15107/rcub_farfar_4777 .

TY  - JOUR
AU  - Konić-Ristić, Aleksandra
AU  - Stanojković, Tatjana
AU  - Srdić-Rajić, Tatjana
AU  - Dilber, Sanda
AU  - Đorđević, Brižita
AU  - Stanković, Ivan
AU  - Juranić, Zorica
PY  - 2016
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2671
AB  - Background/Aim. Numerous epidemiological studies have shown beneficial effects of cruciferous vegetables consumption in cancer chemoprevention. Biologically active compounds of different Brassicaceae species with antitumor potential are isothiocyanates, present in the form of their precursors - glucosinolates. The aim of this study was to determine the selectivity of antiproliferative action of dietary isothiocyanates for malignant versus normal cells. Methods. Antiproliferative activity of three isothiocyanates abundant in human diet: sulforaphane, benzyl isothiocyanate (BITC) and phenylethyl isothiocyanate, on human cervix carcinoma cell line - HeLa, melanoma cell line - Fem-x, and colon cancer cell line - LS 174, and on peripheral blood mononuclear cells (PBMC), with or without mitogen, were determined by MTT colorimetric assay 72 h after their continuous action. Results. All investigated isothiocyanates inhibited the proliferation of HeLa, Fem-x and LS 174 cells. On all cell lines treated, BITC was the most potent inhibitor of cell proliferation with half-maximum inhibitory concentration (IC50) values of 5.04 mmoL m-3 on HeLa cells, 2.76 mmol m-3 on Fem-x, and 14.30 mmol m-3 on LS 174 cells. Antiproliferative effects on human PBMC were with higher IC50 than on malignant cells. Indexes of selectivity, calculated as a ratio between IC50 values obtained on PBMC and malignant cells, were between 1.12 and 16.57, with the highest values obtained for the action of BITC on melanoma Fem-x cells. Conclusion. Based on its antiproliferative effects on malignant cells, as well as the selectivity of the action to malignant vs normal cells, benzyl isothiocyanate can be considered as a promising candidate in cancer chemoprevention. In general, the safety of investigated compounds, in addition to their antitumor potential, should be considered as an important criterion in cancer chemoprevention. Screening of selectivity is a plausible approach to the evaluation of safety of both natural isothiocyanates and synthesised analogues of these bioactive compounds.
AB  - Uvod/Cilj. Brojne epidemiološke studije pokazale su povoljne efekte konzumiranja povrća iz familije kupusnjača (Brassicaceae) u hemioprevenciji karcinoma. Osnovni biološki aktivni sastojci ovog povrća su izotiocijanati, prisutni u obliku prekursora - glukozinolata. Cilj ovog rada bio je određivanje selektivnosti antiproliferativnog delovanja dijetetskih izotiocijanata na maligne ćelije u odnosu na normalne ćelije. Metode. Antiproliferativna aktivnost tri izotiocijanata zastupljena u ljudskoj ishrani: sulforafana (SFN), benzil-izotiocijanata (BITC) i feniletil-izotiocijanata (FEITC) na humane maligne ćelijske linije, HeLa, ćelijsku liniju karcinoma grlića materice, Fem-x, ćelijsku liniju melanoma, i LS 174, ćelijsku liniju karcinoma kolona, kao i na mononuklearne ćelije periferne krvi (MNĆPK), sa ili bez delovanja mitogena, određivana je MTT kalorimetrijskim testom, 72 h nakon kontinuiranog delovanja agenasa. Rezultati. Svi ispitivani izotiocijanati inhibirali su proliferaciju HeLa, Fem-x i LS 174 ćelija. Na svim ćelijskim linijama BITC je pokazao najizraženije delovanje sa vrednostima polumaksimalne inhibitorne koncentracije (IC50) od 5.04 mmol m-3 na HeLa ćelijama, 2,76 mmoL m-3 na Fem-x i 14,30 mmol m-3 na LS 174 ćelijama. Svi ispitivani izotiocijanati pokazali su citotoksično delovanje na MNĆPK, ali sa višim IC50 vrednostima u odnosu na maligne ćelije. Indeksi selektivnosti antitumorkog delovanja, izraženi kao odnos IC50 vrednosti dobijenih na MNĆPK i malignim ćelijama, bili su između 1,12 i 16,57, sa najvišom vrednosti pri delovanju BITC na Fem-x ćelije. Zaključak. Na osnovu antiproliferativne aktivnosti na maligne ćelije i selektivnosti antiproliferativnog delovanja na maligne u odnosu na normalne ćelije, benzil izotiocijanat se ističe kao perspektivni agens u hemioprevenciji karcinoma. Generalno, pored antitumorskog delovanja, bezbednost primene ovih jedinjenja treba da predstavlja važan kriterijum u izboru odgovarajućih izotiocijanata za primenu u primarnoj, sekundarnoj i tercijarnoj hemioprevenciji kancera. Ispitivanje selektivnosti predstavlja pogodan pristup oceni bezbednosti i prirodnih izotiocijanata i sintetskih analoga.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski pregled
T1  - In vitro assessment of antiproliferative action selectivity of dietary isothiocyanates for tumor versus normal human cells
T1  - In vitro ispitivanje selektivnosti antiproliferativnog dejstva dijetetskih izotiocijanata na tumorske u odnosu na normalne humane ćelije
VL  - 73
IS  - 7
SP  - 636
EP  - 642
DO  - 10.2298/VSP141103066K
ER  - 

@article{
author = "Konić-Ristić, Aleksandra and Stanojković, Tatjana and Srdić-Rajić, Tatjana and Dilber, Sanda and Đorđević, Brižita and Stanković, Ivan and Juranić, Zorica",
year = "2016",
abstract = "Background/Aim. Numerous epidemiological studies have shown beneficial effects of cruciferous vegetables consumption in cancer chemoprevention. Biologically active compounds of different Brassicaceae species with antitumor potential are isothiocyanates, present in the form of their precursors - glucosinolates. The aim of this study was to determine the selectivity of antiproliferative action of dietary isothiocyanates for malignant versus normal cells. Methods. Antiproliferative activity of three isothiocyanates abundant in human diet: sulforaphane, benzyl isothiocyanate (BITC) and phenylethyl isothiocyanate, on human cervix carcinoma cell line - HeLa, melanoma cell line - Fem-x, and colon cancer cell line - LS 174, and on peripheral blood mononuclear cells (PBMC), with or without mitogen, were determined by MTT colorimetric assay 72 h after their continuous action. Results. All investigated isothiocyanates inhibited the proliferation of HeLa, Fem-x and LS 174 cells. On all cell lines treated, BITC was the most potent inhibitor of cell proliferation with half-maximum inhibitory concentration (IC50) values of 5.04 mmoL m-3 on HeLa cells, 2.76 mmol m-3 on Fem-x, and 14.30 mmol m-3 on LS 174 cells. Antiproliferative effects on human PBMC were with higher IC50 than on malignant cells. Indexes of selectivity, calculated as a ratio between IC50 values obtained on PBMC and malignant cells, were between 1.12 and 16.57, with the highest values obtained for the action of BITC on melanoma Fem-x cells. Conclusion. Based on its antiproliferative effects on malignant cells, as well as the selectivity of the action to malignant vs normal cells, benzyl isothiocyanate can be considered as a promising candidate in cancer chemoprevention. In general, the safety of investigated compounds, in addition to their antitumor potential, should be considered as an important criterion in cancer chemoprevention. Screening of selectivity is a plausible approach to the evaluation of safety of both natural isothiocyanates and synthesised analogues of these bioactive compounds., Uvod/Cilj. Brojne epidemiološke studije pokazale su povoljne efekte konzumiranja povrća iz familije kupusnjača (Brassicaceae) u hemioprevenciji karcinoma. Osnovni biološki aktivni sastojci ovog povrća su izotiocijanati, prisutni u obliku prekursora - glukozinolata. Cilj ovog rada bio je određivanje selektivnosti antiproliferativnog delovanja dijetetskih izotiocijanata na maligne ćelije u odnosu na normalne ćelije. Metode. Antiproliferativna aktivnost tri izotiocijanata zastupljena u ljudskoj ishrani: sulforafana (SFN), benzil-izotiocijanata (BITC) i feniletil-izotiocijanata (FEITC) na humane maligne ćelijske linije, HeLa, ćelijsku liniju karcinoma grlića materice, Fem-x, ćelijsku liniju melanoma, i LS 174, ćelijsku liniju karcinoma kolona, kao i na mononuklearne ćelije periferne krvi (MNĆPK), sa ili bez delovanja mitogena, određivana je MTT kalorimetrijskim testom, 72 h nakon kontinuiranog delovanja agenasa. Rezultati. Svi ispitivani izotiocijanati inhibirali su proliferaciju HeLa, Fem-x i LS 174 ćelija. Na svim ćelijskim linijama BITC je pokazao najizraženije delovanje sa vrednostima polumaksimalne inhibitorne koncentracije (IC50) od 5.04 mmol m-3 na HeLa ćelijama, 2,76 mmoL m-3 na Fem-x i 14,30 mmol m-3 na LS 174 ćelijama. Svi ispitivani izotiocijanati pokazali su citotoksično delovanje na MNĆPK, ali sa višim IC50 vrednostima u odnosu na maligne ćelije. Indeksi selektivnosti antitumorkog delovanja, izraženi kao odnos IC50 vrednosti dobijenih na MNĆPK i malignim ćelijama, bili su između 1,12 i 16,57, sa najvišom vrednosti pri delovanju BITC na Fem-x ćelije. Zaključak. Na osnovu antiproliferativne aktivnosti na maligne ćelije i selektivnosti antiproliferativnog delovanja na maligne u odnosu na normalne ćelije, benzil izotiocijanat se ističe kao perspektivni agens u hemioprevenciji karcinoma. Generalno, pored antitumorskog delovanja, bezbednost primene ovih jedinjenja treba da predstavlja važan kriterijum u izboru odgovarajućih izotiocijanata za primenu u primarnoj, sekundarnoj i tercijarnoj hemioprevenciji kancera. Ispitivanje selektivnosti predstavlja pogodan pristup oceni bezbednosti i prirodnih izotiocijanata i sintetskih analoga.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski pregled",
title = "In vitro assessment of antiproliferative action selectivity of dietary isothiocyanates for tumor versus normal human cells, In vitro ispitivanje selektivnosti antiproliferativnog dejstva dijetetskih izotiocijanata na tumorske u odnosu na normalne humane ćelije",
volume = "73",
number = "7",
pages = "636-642",
doi = "10.2298/VSP141103066K"
}

Konić-Ristić, A., Stanojković, T., Srdić-Rajić, T., Dilber, S., Đorđević, B., Stanković, I.,& Juranić, Z.. (2016). In vitro assessment of antiproliferative action selectivity of dietary isothiocyanates for tumor versus normal human cells. in Vojnosanitetski pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 73(7), 636-642.
https://doi.org/10.2298/VSP141103066K

Konić-Ristić A, Stanojković T, Srdić-Rajić T, Dilber S, Đorđević B, Stanković I, Juranić Z. In vitro assessment of antiproliferative action selectivity of dietary isothiocyanates for tumor versus normal human cells. in Vojnosanitetski pregled. 2016;73(7):636-642.
doi:10.2298/VSP141103066K .

Konić-Ristić, Aleksandra, Stanojković, Tatjana, Srdić-Rajić, Tatjana, Dilber, Sanda, Đorđević, Brižita, Stanković, Ivan, Juranić, Zorica, "In vitro assessment of antiproliferative action selectivity of dietary isothiocyanates for tumor versus normal human cells" in Vojnosanitetski pregled, 73, no. 7 (2016):636-642,
https://doi.org/10.2298/VSP141103066K . .

TY  - CONF
AU  - Konić-Ristić, Aleksandra
AU  - Zrnić-Ćirić, Milica
AU  - Stanković, Ivan
AU  - Srdić-Rajić, Tatjana
AU  - Kardum, Nevena
AU  - Glibetić, Marija
PY  - 2015
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5398
AB  - It has been suggested that impairment of intestinal wall integrity may contribute to the low-grade inflammation in subjects with metabolic distribances and foster progression of cardiovascular, liver or neurological diseases. Recent studies provide evidence that dietary polyphenols may important role in gut health and homeostasis, as one of the proposed mechanisms of their beneficial systemic effects.
PB  - Institut National de la Recherche Agronomique (INRA), France
PB  - Institut National de la Santé et de la Recherche Médicale (INSERM), France
C3  - 7th International Conference on Polyphenols and Health (ICPH 2015), 27 - 30 October 2015, Congress Center Tours, France
T1  - Long term consumption of Aronia juice decreases serum zonulin levels and the expression of cd11b on monocytes in subjects at high cvd risk
SP  - 198
EP  - 198
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5398
ER  - 

@conference{
author = "Konić-Ristić, Aleksandra and Zrnić-Ćirić, Milica and Stanković, Ivan and Srdić-Rajić, Tatjana and Kardum, Nevena and Glibetić, Marija",
year = "2015",
abstract = "It has been suggested that impairment of intestinal wall integrity may contribute to the low-grade inflammation in subjects with metabolic distribances and foster progression of cardiovascular, liver or neurological diseases. Recent studies provide evidence that dietary polyphenols may important role in gut health and homeostasis, as one of the proposed mechanisms of their beneficial systemic effects.",
publisher = "Institut National de la Recherche Agronomique (INRA), France, Institut National de la Santé et de la Recherche Médicale (INSERM), France",
journal = "7th International Conference on Polyphenols and Health (ICPH 2015), 27 - 30 October 2015, Congress Center Tours, France",
title = "Long term consumption of Aronia juice decreases serum zonulin levels and the expression of cd11b on monocytes in subjects at high cvd risk",
pages = "198-198",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5398"
}

Konić-Ristić, A., Zrnić-Ćirić, M., Stanković, I., Srdić-Rajić, T., Kardum, N.,& Glibetić, M.. (2015). Long term consumption of Aronia juice decreases serum zonulin levels and the expression of cd11b on monocytes in subjects at high cvd risk. in 7th International Conference on Polyphenols and Health (ICPH 2015), 27 - 30 October 2015, Congress Center Tours, France
Institut National de la Recherche Agronomique (INRA), France., 198-198.
https://hdl.handle.net/21.15107/rcub_farfar_5398

Konić-Ristić A, Zrnić-Ćirić M, Stanković I, Srdić-Rajić T, Kardum N, Glibetić M. Long term consumption of Aronia juice decreases serum zonulin levels and the expression of cd11b on monocytes in subjects at high cvd risk. in 7th International Conference on Polyphenols and Health (ICPH 2015), 27 - 30 October 2015, Congress Center Tours, France. 2015;:198-198.
https://hdl.handle.net/21.15107/rcub_farfar_5398 .

Konić-Ristić, Aleksandra, Zrnić-Ćirić, Milica, Stanković, Ivan, Srdić-Rajić, Tatjana, Kardum, Nevena, Glibetić, Marija, "Long term consumption of Aronia juice decreases serum zonulin levels and the expression of cd11b on monocytes in subjects at high cvd risk" in 7th International Conference on Polyphenols and Health (ICPH 2015), 27 - 30 October 2015, Congress Center Tours, France (2015):198-198,
https://hdl.handle.net/21.15107/rcub_farfar_5398 .

TY  - JOUR
AU  - Kardum, Nevena
AU  - Konić-Ristić, Aleksandra
AU  - Šavikin, Katarina
AU  - Spasić, Slavica
AU  - Stefanović, Aleksandra
AU  - Ivanišević, Jasmina
AU  - Miljković, Milica
PY  - 2014
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2100
AB  - Berry fruits are a rich source of polyphenols, especially anthocyanins: well-known potent anti-oxidant phytochemicals. The purpose of this study was to evaluate beneficial effects of long-term consumption of polyphenol-rich organic chokeberry juice on different markers of antioxidant/pro-oxidant status in healthy female volunteers. Twenty-nine women, aged 25-49, were included in the study. Serological markers of oxidative stress and antioxidant defence, blood pressure, routine biochemical, and anthropometric parameters were analyzed at baseline and after twelve weeks of regular chokeberry juice consumption. Significant decrease in thiobarbituric acid-reactive substances level (TBARS; P  lt  .001) and pro-oxidant-antioxidant balance (PAB; P  lt  .05), as well as increase in paroxonase-1 activity toward diazoxon (P  lt  .01) were found. Total oxidative status and sulphydryl groups levels were not significantly influenced by the intervention. Anthropometric, biochemical parameters, and blood pressure values were within the referent values for all subjects and were not influenced by the chokeberry juice consumption. However, we found positive correlation between age, body mass index, waist circumference, body fat percent, blood pressure, and analyzed marker of lipid peroxidation, which was influenced by the consumption. In conclusion, the fine modulation of several antioxidant/pro-oxidant status biomarkers observed in healthy subjects indicates putative prophylactic effects of polyphenol-rich chokeberry juice and supports its importance as part of an optimal diet.
PB  - Mary Ann Liebert, Inc, New Rochelle
T2  - Journal of Medicinal Food
T1  - Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects
VL  - 17
IS  - 8
SP  - 869
EP  - 874
DO  - 10.1089/jmf.2013.0135
ER  - 

@article{
author = "Kardum, Nevena and Konić-Ristić, Aleksandra and Šavikin, Katarina and Spasić, Slavica and Stefanović, Aleksandra and Ivanišević, Jasmina and Miljković, Milica",
year = "2014",
abstract = "Berry fruits are a rich source of polyphenols, especially anthocyanins: well-known potent anti-oxidant phytochemicals. The purpose of this study was to evaluate beneficial effects of long-term consumption of polyphenol-rich organic chokeberry juice on different markers of antioxidant/pro-oxidant status in healthy female volunteers. Twenty-nine women, aged 25-49, were included in the study. Serological markers of oxidative stress and antioxidant defence, blood pressure, routine biochemical, and anthropometric parameters were analyzed at baseline and after twelve weeks of regular chokeberry juice consumption. Significant decrease in thiobarbituric acid-reactive substances level (TBARS; P  lt  .001) and pro-oxidant-antioxidant balance (PAB; P  lt  .05), as well as increase in paroxonase-1 activity toward diazoxon (P  lt  .01) were found. Total oxidative status and sulphydryl groups levels were not significantly influenced by the intervention. Anthropometric, biochemical parameters, and blood pressure values were within the referent values for all subjects and were not influenced by the chokeberry juice consumption. However, we found positive correlation between age, body mass index, waist circumference, body fat percent, blood pressure, and analyzed marker of lipid peroxidation, which was influenced by the consumption. In conclusion, the fine modulation of several antioxidant/pro-oxidant status biomarkers observed in healthy subjects indicates putative prophylactic effects of polyphenol-rich chokeberry juice and supports its importance as part of an optimal diet.",
publisher = "Mary Ann Liebert, Inc, New Rochelle",
journal = "Journal of Medicinal Food",
title = "Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects",
volume = "17",
number = "8",
pages = "869-874",
doi = "10.1089/jmf.2013.0135"
}

Kardum, N., Konić-Ristić, A., Šavikin, K., Spasić, S., Stefanović, A., Ivanišević, J.,& Miljković, M.. (2014). Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects. in Journal of Medicinal Food
Mary Ann Liebert, Inc, New Rochelle., 17(8), 869-874.
https://doi.org/10.1089/jmf.2013.0135

Kardum N, Konić-Ristić A, Šavikin K, Spasić S, Stefanović A, Ivanišević J, Miljković M. Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects. in Journal of Medicinal Food. 2014;17(8):869-874.
doi:10.1089/jmf.2013.0135 .

Kardum, Nevena, Konić-Ristić, Aleksandra, Šavikin, Katarina, Spasić, Slavica, Stefanović, Aleksandra, Ivanišević, Jasmina, Miljković, Milica, "Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects" in Journal of Medicinal Food, 17, no. 8 (2014):869-874,
https://doi.org/10.1089/jmf.2013.0135 . .

TY  - JOUR
AU  - Konić-Ristić, Aleksandra
AU  - Šavikin, Katarina
AU  - Zdunić, Gordana
AU  - Janković, Teodora
AU  - Juranić, Zorica
AU  - Menković, Nebojša
AU  - Stanković, Ivan
PY  - 2011
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1497
AB  - Total phenolics total anthocyanins mineral content radical scavenging activity and antiproliferative activity against human cancer cell lines were evaluated in fresh pressed juices of five different berries Total phenolic content ranged from 133 0 to 260 3 mg of gallic acid equivalents/100 g of fresh weight for red currant and black currant respectively Bilberry Juice contained the highest amount of total anthocyanins (0 18%) Significant correlation between total phenolics content and radical scavenging activity was observed (r = -0980 p  lt  0 01) All examined juices showed antiproliferative activity in dose-dependent manner with IC50 ranging from 10 2 to 70 5 mu l/ml Black currant juice was the most effective inhibitor of proliferation in all cell lines tested (HeLa Fem X LS 174 MCF-7 and PC-3) Significant correlations of acidity and total anthocyanin content with antiproliferative activity of berry juices on HeLa cells Fem X cells and MCF-7 cells were noticed Berry juices are good sources of some minerals and contribute significantly to daily intake of these micronutrients
PB  - Elsevier Sci Ltd, Oxford
T2  - Food Chemistry
T1  - Biological activity and chemical composition of different berry juices
VL  - 125
IS  - 4
SP  - 1412
EP  - 1417
DO  - 10.1016/j.foodchem.2010.10.018
ER  - 

@article{
author = "Konić-Ristić, Aleksandra and Šavikin, Katarina and Zdunić, Gordana and Janković, Teodora and Juranić, Zorica and Menković, Nebojša and Stanković, Ivan",
year = "2011",
abstract = "Total phenolics total anthocyanins mineral content radical scavenging activity and antiproliferative activity against human cancer cell lines were evaluated in fresh pressed juices of five different berries Total phenolic content ranged from 133 0 to 260 3 mg of gallic acid equivalents/100 g of fresh weight for red currant and black currant respectively Bilberry Juice contained the highest amount of total anthocyanins (0 18%) Significant correlation between total phenolics content and radical scavenging activity was observed (r = -0980 p  lt  0 01) All examined juices showed antiproliferative activity in dose-dependent manner with IC50 ranging from 10 2 to 70 5 mu l/ml Black currant juice was the most effective inhibitor of proliferation in all cell lines tested (HeLa Fem X LS 174 MCF-7 and PC-3) Significant correlations of acidity and total anthocyanin content with antiproliferative activity of berry juices on HeLa cells Fem X cells and MCF-7 cells were noticed Berry juices are good sources of some minerals and contribute significantly to daily intake of these micronutrients",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Food Chemistry",
title = "Biological activity and chemical composition of different berry juices",
volume = "125",
number = "4",
pages = "1412-1417",
doi = "10.1016/j.foodchem.2010.10.018"
}

Konić-Ristić, A., Šavikin, K., Zdunić, G., Janković, T., Juranić, Z., Menković, N.,& Stanković, I.. (2011). Biological activity and chemical composition of different berry juices. in Food Chemistry
Elsevier Sci Ltd, Oxford., 125(4), 1412-1417.
https://doi.org/10.1016/j.foodchem.2010.10.018

Konić-Ristić A, Šavikin K, Zdunić G, Janković T, Juranić Z, Menković N, Stanković I. Biological activity and chemical composition of different berry juices. in Food Chemistry. 2011;125(4):1412-1417.
doi:10.1016/j.foodchem.2010.10.018 .

Konić-Ristić, Aleksandra, Šavikin, Katarina, Zdunić, Gordana, Janković, Teodora, Juranić, Zorica, Menković, Nebojša, Stanković, Ivan, "Biological activity and chemical composition of different berry juices" in Food Chemistry, 125, no. 4 (2011):1412-1417,
https://doi.org/10.1016/j.foodchem.2010.10.018 . .

TY  - JOUR
AU  - Stanković, Ivan
AU  - Konić-Ristić, Aleksandra
AU  - Delević, Veselin
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1422
AB  - Substances with hormonal activity in food can be of natural origin like hormones in milk and milk product and phytoestrogens, or residues of hormones used as growth promoters or drugs for farm animals. It is estimated that 60-80% of the total intake of hormones with food is from milk and milk products. During pregnancy levels of estrogens and progesterone are significantly increasing and becoming the highest before parturition. Results of the number of studies indicate that dietary intake of estrogens from milk and milk product can be the risk factor for hormone-dependent carcinomas, or same reproductive disorders. Phytoestrogens could have some benefitial effects on hormonal balance especially for women in menopause but additional investigations are needed for their safe use and appropriate dosing in food supplements. In some countries (USA, Canada, Australia) controlled use of hormones as growth promoters is legal, while in EU and Serbia the use of hormones in food production is strictly prohibited. To prevent the illegal use of hormones it is important to establish the national program for monitoring of residues of hormones in food.
AB  - Hormoni u namirnicama mogu da budu prirodnog porekla kao što su hormoni u mleku i fitoestrogeni, ili rezidue hormonskih stimulatora rasta i lekova korišćenih u terapiji životinja. Procenjuje se da 60-80% ukupnog unosa hormona hranom potiče iz mleka i mlečnih proizvoda. U toku graviditeta nivo estrogena i progesterona se značajno povećava i maksimum postiže pred teljenje. Rezultati velikog broja studija ukazuju da dijetarni unos estrogena iz mleka i mlečnih proizvoda može da bude faktor rizika za hormon-zavisne karcinome, ali i za smanjenje reproduktivne spospobnosti, ginekomastiju kod dečaka i prevremeni pubertet kod devojčica. Smatra se da bi supstance sa hormonskom aktivnošću iz nekih namirnica biljnog porekla (fitoestrogeni) mogle da imaju pozitivan efekat u uspostavljanju hormonske ravnoteže kod žena u menopauzi ali su potrebna dodatna ispitivanja za njihovu bezbednu upotrebu i adekvatno doziranje u dijetetskim suplementima. U nekim zemljama (SAD, Kanada, Australija) dozvoljena je kontrolisana primena hormona kao stimulatora rasta životinja, dok je u EU i Srbiji njihova upotreba strogo zabranjena. Zbog ilegalnog korišćenja hormona u proizvodnji hrane potrebno je uspostaviti nacionalni program monitoringa rezidua hormona u namirnicama.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Hormones in food
T1  - Hormoni u namirnicama
VL  - 60
IS  - 2
SP  - 198
EP  - 206
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1422
ER  - 

@article{
author = "Stanković, Ivan and Konić-Ristić, Aleksandra and Delević, Veselin",
year = "2010",
abstract = "Substances with hormonal activity in food can be of natural origin like hormones in milk and milk product and phytoestrogens, or residues of hormones used as growth promoters or drugs for farm animals. It is estimated that 60-80% of the total intake of hormones with food is from milk and milk products. During pregnancy levels of estrogens and progesterone are significantly increasing and becoming the highest before parturition. Results of the number of studies indicate that dietary intake of estrogens from milk and milk product can be the risk factor for hormone-dependent carcinomas, or same reproductive disorders. Phytoestrogens could have some benefitial effects on hormonal balance especially for women in menopause but additional investigations are needed for their safe use and appropriate dosing in food supplements. In some countries (USA, Canada, Australia) controlled use of hormones as growth promoters is legal, while in EU and Serbia the use of hormones in food production is strictly prohibited. To prevent the illegal use of hormones it is important to establish the national program for monitoring of residues of hormones in food., Hormoni u namirnicama mogu da budu prirodnog porekla kao što su hormoni u mleku i fitoestrogeni, ili rezidue hormonskih stimulatora rasta i lekova korišćenih u terapiji životinja. Procenjuje se da 60-80% ukupnog unosa hormona hranom potiče iz mleka i mlečnih proizvoda. U toku graviditeta nivo estrogena i progesterona se značajno povećava i maksimum postiže pred teljenje. Rezultati velikog broja studija ukazuju da dijetarni unos estrogena iz mleka i mlečnih proizvoda može da bude faktor rizika za hormon-zavisne karcinome, ali i za smanjenje reproduktivne spospobnosti, ginekomastiju kod dečaka i prevremeni pubertet kod devojčica. Smatra se da bi supstance sa hormonskom aktivnošću iz nekih namirnica biljnog porekla (fitoestrogeni) mogle da imaju pozitivan efekat u uspostavljanju hormonske ravnoteže kod žena u menopauzi ali su potrebna dodatna ispitivanja za njihovu bezbednu upotrebu i adekvatno doziranje u dijetetskim suplementima. U nekim zemljama (SAD, Kanada, Australija) dozvoljena je kontrolisana primena hormona kao stimulatora rasta životinja, dok je u EU i Srbiji njihova upotreba strogo zabranjena. Zbog ilegalnog korišćenja hormona u proizvodnji hrane potrebno je uspostaviti nacionalni program monitoringa rezidua hormona u namirnicama.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Hormones in food, Hormoni u namirnicama",
volume = "60",
number = "2",
pages = "198-206",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1422"
}

Stanković, I., Konić-Ristić, A.,& Delević, V.. (2010). Hormones in food. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 60(2), 198-206.
https://hdl.handle.net/21.15107/rcub_farfar_1422

Stanković I, Konić-Ristić A, Delević V. Hormones in food. in Arhiv za farmaciju. 2010;60(2):198-206.
https://hdl.handle.net/21.15107/rcub_farfar_1422 .

Stanković, Ivan, Konić-Ristić, Aleksandra, Delević, Veselin, "Hormones in food" in Arhiv za farmaciju, 60, no. 2 (2010):198-206,
https://hdl.handle.net/21.15107/rcub_farfar_1422 .

TY  - JOUR
AU  - Stanković, Ivan
AU  - Konić-Ristić, Aleksandra
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1303
AB  - There has been increasing interest in the preventive and therapeutic uses of prebiotics, probiotics and sinbiotics as their combinations. Their health-promoting and therapeutic properties have been shown in numerous clinical studies and investigations. For that reason and because of the long history of their use they are increasingly accepted by the consumers, especially in the form of food. This article reviews the most frequently used probiotics and prebiotics, the proposed mechanisms and beneficial effects and different criteria in the process of selection and use as simbiotics. Future research should be focused on clinical trials investigating all potential effects, definition of appropriate methods for their selection, investigation of potential micro organisms and agents with positive effects on gut health, issues regarding safety, dosing, mechanisms and appropriate application.
AB  - Interesovanje za probiotike, prebiotike i njihove kombinacije (sinbiotike) povećava se iz dana u dan. Brojni pozitivni efekti na ljudsko zdravlje potvrđeni su velikim brojem eksperimenata i kliničkih ispitivanja. Zahvaljujući tome, ali i činjenici da u osnovi imaju dugu istoriju primene, oni su sve više prihvaćeni od strane potrošača, i prevazilaze granice komplementarne medicine, zauzimajući značajno mesto kako u promociji zdravlja i prevenciji bolesti, tako i u terapiji simptoma pojedinih bolesti. U ovom radu predstavljeni su najčešće korišćeni probiotici i prebiotici, osnovni mehanizminjihovog delovanja, potvrđeni i predloženi efekti u preventivi i terapiji pojedinih bolesti, kao i kriterijumi u njihovoj selekciji. Buduća istraživanja u ovoj oblasti pre svega obuhvataju veći broj kliničkih studija i istraživanja, razvoj metoda za procenu efikasnosti i selekciju optimalnih kandidata, tehnološka usavršavanja proizvodnje kao i ispitivanja bezbednosti, optimalne doze i primerene upotrebe ovih agenasa.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Probiotics, prebiotics and sinbiotics
T1  - Probiotici, prebiotici i sinbiotici
VL  - 59
IS  - 2-3
SP  - 169
EP  - 181
UR  - https://hdl.handle.net/21.15107/rcub_farfar_1303
ER  - 

@article{
author = "Stanković, Ivan and Konić-Ristić, Aleksandra",
year = "2009",
abstract = "There has been increasing interest in the preventive and therapeutic uses of prebiotics, probiotics and sinbiotics as their combinations. Their health-promoting and therapeutic properties have been shown in numerous clinical studies and investigations. For that reason and because of the long history of their use they are increasingly accepted by the consumers, especially in the form of food. This article reviews the most frequently used probiotics and prebiotics, the proposed mechanisms and beneficial effects and different criteria in the process of selection and use as simbiotics. Future research should be focused on clinical trials investigating all potential effects, definition of appropriate methods for their selection, investigation of potential micro organisms and agents with positive effects on gut health, issues regarding safety, dosing, mechanisms and appropriate application., Interesovanje za probiotike, prebiotike i njihove kombinacije (sinbiotike) povećava se iz dana u dan. Brojni pozitivni efekti na ljudsko zdravlje potvrđeni su velikim brojem eksperimenata i kliničkih ispitivanja. Zahvaljujući tome, ali i činjenici da u osnovi imaju dugu istoriju primene, oni su sve više prihvaćeni od strane potrošača, i prevazilaze granice komplementarne medicine, zauzimajući značajno mesto kako u promociji zdravlja i prevenciji bolesti, tako i u terapiji simptoma pojedinih bolesti. U ovom radu predstavljeni su najčešće korišćeni probiotici i prebiotici, osnovni mehanizminjihovog delovanja, potvrđeni i predloženi efekti u preventivi i terapiji pojedinih bolesti, kao i kriterijumi u njihovoj selekciji. Buduća istraživanja u ovoj oblasti pre svega obuhvataju veći broj kliničkih studija i istraživanja, razvoj metoda za procenu efikasnosti i selekciju optimalnih kandidata, tehnološka usavršavanja proizvodnje kao i ispitivanja bezbednosti, optimalne doze i primerene upotrebe ovih agenasa.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Probiotics, prebiotics and sinbiotics, Probiotici, prebiotici i sinbiotici",
volume = "59",
number = "2-3",
pages = "169-181",
url = "https://hdl.handle.net/21.15107/rcub_farfar_1303"
}

Stanković, I.,& Konić-Ristić, A.. (2009). Probiotics, prebiotics and sinbiotics. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 59(2-3), 169-181.
https://hdl.handle.net/21.15107/rcub_farfar_1303

Stanković I, Konić-Ristić A. Probiotics, prebiotics and sinbiotics. in Arhiv za farmaciju. 2009;59(2-3):169-181.
https://hdl.handle.net/21.15107/rcub_farfar_1303 .

Stanković, Ivan, Konić-Ristić, Aleksandra, "Probiotics, prebiotics and sinbiotics" in Arhiv za farmaciju, 59, no. 2-3 (2009):169-181,
https://hdl.handle.net/21.15107/rcub_farfar_1303 .

TY  - JOUR
AU  - Konić-Ristić, Aleksandra
AU  - Dodig, Dejan
AU  - Krstić, Radmilo
AU  - Jelić, Svetislav
AU  - Stanković, Ivan
AU  - Ninković, Aleksandra
AU  - Radić, Jelena
AU  - Besu, Irina
AU  - Bonaci-Nikolić, Branka
AU  - Jojić, Njegica
AU  - Đorđević, Milica
AU  - Popović, Dragan
AU  - Juranić, Zorica
PY  - 2009
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1238
AB  - Background: Immunity to food antigens (gliadin, cow's milk proteins) is in the centre of the attention of modern medicine focused on the prevention of diseases, prevention which is based on the use of appropriate restriction diet. Detection of the enhanced levels of the immune reactions to antigen(s) present in food is from this point of view of great importance because there are reports that some of health disturbances, like celiac disease (CD) and some premalignant conditions, like monoclonal gammopathy of undetermined significance (MGUS), were vanished after the appropriate restriction diets. It is well known that gliadin is toxic to small bowel mucosa of relatively small population of genetically predisposed individuals, who under this toxic action develop celiac disease (CD). As the quantity of immunogenic gliadin could vary between different wheat species, the first aim of this work was to determine the percentage of immunogenic gliadin in ten bread wheat cultivars and in three commercially grown durum wheat cultivars. The second part of the study was initiated by results of previous publication, reporting that sera of some of multiple myeloma (MM) patients showed the presence of elevated levels of anti-gliadin IgA, without the enhanced levels of anti-gliadin IgG antibodies, determined with commercial ELISA test. It was designed to assess is it possible to reveal is there any hidden, especially anti-gliadin IgG immunoreactivity, in serum of mentioned group of patients. For this purpose we tested MM patients sera, as well as celiac disease (CD) patients sera for the immunoreaction with the native gliadin isolated from wheat species used for bread and pasta making in corresponding geographic region. Results: Gliadin was isolated from wheat flour by two step 60% ehanolic extraction. Its content was determined by commercial R5 Mendez Elisa using PWG gliadin as the standard. Results obtained showed that immunogenic gliadin content varies between 50.4 and 65.4 mg/g in bread wheat cultivars and between 20 and 25.6 mg/g in durum wheat cultivars. Anti-gliadin IgA and IgG immunoreactivity of patients' sera in (IU/ml) was firstly determined by commercial diagnostic Binding Site ELISA test, and then additionally by non-commercial ELISA tests, using standardized ethanol wheat extracts-gliadin as the antigen. In both patients groups IgA immunoreactivity to gliadin from different cultivars was almost homogenous and in correlation with results from commercial test (except for one patient with IgA(lambda) myeloma, they were more then five times higher). But, results for IgG immunoreactivity were more frequently inhomogeneous, and especially for few MM patients, they were more then five times higher and did not correlate with results obtained using Binding Site test. Conclusion: Results obtained showed different content of immunogenic gliadin epitopes in various species of wheat. They also point for new effort to elucidate is there a need to develop new standard antigen, the representative mixture of gliadin isolated from local wheat species used for bread production in corresponding geographic region for ELISA diagnostic tests.
PB  - BMC, LONDON
T2  - BMC Immunology
T1  - Different levels of humoral immunoreactivity to different wheat cultivars gliadin are present in patients with celiac disease and in patients with multiple myeloma
VL  - 10
DO  - 10.1186/1471-2172-10-32
ER  - 

@article{
author = "Konić-Ristić, Aleksandra and Dodig, Dejan and Krstić, Radmilo and Jelić, Svetislav and Stanković, Ivan and Ninković, Aleksandra and Radić, Jelena and Besu, Irina and Bonaci-Nikolić, Branka and Jojić, Njegica and Đorđević, Milica and Popović, Dragan and Juranić, Zorica",
year = "2009",
abstract = "Background: Immunity to food antigens (gliadin, cow's milk proteins) is in the centre of the attention of modern medicine focused on the prevention of diseases, prevention which is based on the use of appropriate restriction diet. Detection of the enhanced levels of the immune reactions to antigen(s) present in food is from this point of view of great importance because there are reports that some of health disturbances, like celiac disease (CD) and some premalignant conditions, like monoclonal gammopathy of undetermined significance (MGUS), were vanished after the appropriate restriction diets. It is well known that gliadin is toxic to small bowel mucosa of relatively small population of genetically predisposed individuals, who under this toxic action develop celiac disease (CD). As the quantity of immunogenic gliadin could vary between different wheat species, the first aim of this work was to determine the percentage of immunogenic gliadin in ten bread wheat cultivars and in three commercially grown durum wheat cultivars. The second part of the study was initiated by results of previous publication, reporting that sera of some of multiple myeloma (MM) patients showed the presence of elevated levels of anti-gliadin IgA, without the enhanced levels of anti-gliadin IgG antibodies, determined with commercial ELISA test. It was designed to assess is it possible to reveal is there any hidden, especially anti-gliadin IgG immunoreactivity, in serum of mentioned group of patients. For this purpose we tested MM patients sera, as well as celiac disease (CD) patients sera for the immunoreaction with the native gliadin isolated from wheat species used for bread and pasta making in corresponding geographic region. Results: Gliadin was isolated from wheat flour by two step 60% ehanolic extraction. Its content was determined by commercial R5 Mendez Elisa using PWG gliadin as the standard. Results obtained showed that immunogenic gliadin content varies between 50.4 and 65.4 mg/g in bread wheat cultivars and between 20 and 25.6 mg/g in durum wheat cultivars. Anti-gliadin IgA and IgG immunoreactivity of patients' sera in (IU/ml) was firstly determined by commercial diagnostic Binding Site ELISA test, and then additionally by non-commercial ELISA tests, using standardized ethanol wheat extracts-gliadin as the antigen. In both patients groups IgA immunoreactivity to gliadin from different cultivars was almost homogenous and in correlation with results from commercial test (except for one patient with IgA(lambda) myeloma, they were more then five times higher). But, results for IgG immunoreactivity were more frequently inhomogeneous, and especially for few MM patients, they were more then five times higher and did not correlate with results obtained using Binding Site test. Conclusion: Results obtained showed different content of immunogenic gliadin epitopes in various species of wheat. They also point for new effort to elucidate is there a need to develop new standard antigen, the representative mixture of gliadin isolated from local wheat species used for bread production in corresponding geographic region for ELISA diagnostic tests.",
publisher = "BMC, LONDON",
journal = "BMC Immunology",
title = "Different levels of humoral immunoreactivity to different wheat cultivars gliadin are present in patients with celiac disease and in patients with multiple myeloma",
volume = "10",
doi = "10.1186/1471-2172-10-32"
}

Konić-Ristić, A., Dodig, D., Krstić, R., Jelić, S., Stanković, I., Ninković, A., Radić, J., Besu, I., Bonaci-Nikolić, B., Jojić, N., Đorđević, M., Popović, D.,& Juranić, Z.. (2009). Different levels of humoral immunoreactivity to different wheat cultivars gliadin are present in patients with celiac disease and in patients with multiple myeloma. in BMC Immunology
BMC, LONDON., 10.
https://doi.org/10.1186/1471-2172-10-32

Konić-Ristić A, Dodig D, Krstić R, Jelić S, Stanković I, Ninković A, Radić J, Besu I, Bonaci-Nikolić B, Jojić N, Đorđević M, Popović D, Juranić Z. Different levels of humoral immunoreactivity to different wheat cultivars gliadin are present in patients with celiac disease and in patients with multiple myeloma. in BMC Immunology. 2009;10.
doi:10.1186/1471-2172-10-32 .

Konić-Ristić, Aleksandra, Dodig, Dejan, Krstić, Radmilo, Jelić, Svetislav, Stanković, Ivan, Ninković, Aleksandra, Radić, Jelena, Besu, Irina, Bonaci-Nikolić, Branka, Jojić, Njegica, Đorđević, Milica, Popović, Dragan, Juranić, Zorica, "Different levels of humoral immunoreactivity to different wheat cultivars gliadin are present in patients with celiac disease and in patients with multiple myeloma" in BMC Immunology, 10 (2009),
https://doi.org/10.1186/1471-2172-10-32 . .

TY  - JOUR
AU  - Juranić, Zorica
AU  - Radić, Jelena
AU  - Konić-Ristić, Aleksandra
AU  - Jelić, Svetislav
AU  - Mihaljević, Biljana
AU  - Stanković, Ivan
AU  - Matković, Suzana
AU  - Besu, Irina
AU  - Gavrilović, Dušica
PY  - 2008
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1071
AB  - Background: Multiple myeloma (MM) is a clonal B-cell disorder with many immunological disturbances. The aim of this work was to assess whether some of food antigens contribute to the imbalance of immune response by screening the sera of MM patients for their immunoreactivity to food constituent gliadin, to tissue transglutaminase-2 (tTG-2) and to Ro/SSA antigen. Sera from 61 patients with MM in various stages of disease, before, or after some cycles of conventional therapy were analyzed by commercial Binding Site ELISA tests. The control group consisted of 50 healthy volunteers. Statistical analysis of data obtained was performed by Mann Whitney Test. Results: The higher serum IgA immunoreactivity to gliadin was found in 14/56 patients and in one of control people. The enhanced serum IgG immunoreactivity to gliadin was found in only two of tested patients and in two controls. The enhanced IgA immunoreactivity to tTG-2 was found in 10/49 patients' sera, while 4/45 patients had higher serum IgG immunoreactivity. The enhanced serum IgG immunoreactivity to RoSSA antigen was found in 9/47 analyzed MM patients' sera. Statistical analysis of data obtained revealed that only the levels of anti-tTG-2 IgA immunoreactivity in patients with MM were significantly higher than these obtained in healthy controls (P  lt  0.02) Conclusion: Data obtained showed the existence of the enhanced serum immunoreactivity to gliadin, tTG-2 and Ro/SSA antigens in some patients with MM. These at least partially could contribute to the immunological imbalance frequently found in this disease.
PB  - BMC, LONDON
T2  - BMC Immunology
T1  - Humoral immunoreactivity to gliadin and to tissue transglutaminase is present in some patients with multiple myeloma
VL  - 9
DO  - 10.1186/1471-2172-9-22
ER  - 

@article{
author = "Juranić, Zorica and Radić, Jelena and Konić-Ristić, Aleksandra and Jelić, Svetislav and Mihaljević, Biljana and Stanković, Ivan and Matković, Suzana and Besu, Irina and Gavrilović, Dušica",
year = "2008",
abstract = "Background: Multiple myeloma (MM) is a clonal B-cell disorder with many immunological disturbances. The aim of this work was to assess whether some of food antigens contribute to the imbalance of immune response by screening the sera of MM patients for their immunoreactivity to food constituent gliadin, to tissue transglutaminase-2 (tTG-2) and to Ro/SSA antigen. Sera from 61 patients with MM in various stages of disease, before, or after some cycles of conventional therapy were analyzed by commercial Binding Site ELISA tests. The control group consisted of 50 healthy volunteers. Statistical analysis of data obtained was performed by Mann Whitney Test. Results: The higher serum IgA immunoreactivity to gliadin was found in 14/56 patients and in one of control people. The enhanced serum IgG immunoreactivity to gliadin was found in only two of tested patients and in two controls. The enhanced IgA immunoreactivity to tTG-2 was found in 10/49 patients' sera, while 4/45 patients had higher serum IgG immunoreactivity. The enhanced serum IgG immunoreactivity to RoSSA antigen was found in 9/47 analyzed MM patients' sera. Statistical analysis of data obtained revealed that only the levels of anti-tTG-2 IgA immunoreactivity in patients with MM were significantly higher than these obtained in healthy controls (P  lt  0.02) Conclusion: Data obtained showed the existence of the enhanced serum immunoreactivity to gliadin, tTG-2 and Ro/SSA antigens in some patients with MM. These at least partially could contribute to the immunological imbalance frequently found in this disease.",
publisher = "BMC, LONDON",
journal = "BMC Immunology",
title = "Humoral immunoreactivity to gliadin and to tissue transglutaminase is present in some patients with multiple myeloma",
volume = "9",
doi = "10.1186/1471-2172-9-22"
}

Juranić, Z., Radić, J., Konić-Ristić, A., Jelić, S., Mihaljević, B., Stanković, I., Matković, S., Besu, I.,& Gavrilović, D.. (2008). Humoral immunoreactivity to gliadin and to tissue transglutaminase is present in some patients with multiple myeloma. in BMC Immunology
BMC, LONDON., 9.
https://doi.org/10.1186/1471-2172-9-22

Juranić Z, Radić J, Konić-Ristić A, Jelić S, Mihaljević B, Stanković I, Matković S, Besu I, Gavrilović D. Humoral immunoreactivity to gliadin and to tissue transglutaminase is present in some patients with multiple myeloma. in BMC Immunology. 2008;9.
doi:10.1186/1471-2172-9-22 .

Juranić, Zorica, Radić, Jelena, Konić-Ristić, Aleksandra, Jelić, Svetislav, Mihaljević, Biljana, Stanković, Ivan, Matković, Suzana, Besu, Irina, Gavrilović, Dušica, "Humoral immunoreactivity to gliadin and to tissue transglutaminase is present in some patients with multiple myeloma" in BMC Immunology, 9 (2008),
https://doi.org/10.1186/1471-2172-9-22 . .

TY  - CONF
AU  - Konić-Ristić, Aleksandra
AU  - Vidović, Bojana
AU  - Šobajić, Slađana
AU  - Stanković, Ivan
AU  - Đorđević, Brižita
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/984
PB  - Karger, Basel
C3  - Annals of Nutrition and Metabolism
T1  - Prevalence rates and trends on underweight, normal weight and overweight/obesity among pharmacy student population in Serbia
VL  - 51
IS  - suppl 1
SP  - 302
EP  - 302
DO  - 10.1159/000105121
ER  - 

@conference{
author = "Konić-Ristić, Aleksandra and Vidović, Bojana and Šobajić, Slađana and Stanković, Ivan and Đorđević, Brižita",
year = "2007",
publisher = "Karger, Basel",
journal = "Annals of Nutrition and Metabolism",
title = "Prevalence rates and trends on underweight, normal weight and overweight/obesity among pharmacy student population in Serbia",
volume = "51",
number = "suppl 1",
pages = "302-302",
doi = "10.1159/000105121"
}

Konić-Ristić, A., Vidović, B., Šobajić, S., Stanković, I.,& Đorđević, B.. (2007). Prevalence rates and trends on underweight, normal weight and overweight/obesity among pharmacy student population in Serbia. in Annals of Nutrition and Metabolism
Karger, Basel., 51(suppl 1), 302-302.
https://doi.org/10.1159/000105121

Konić-Ristić A, Vidović B, Šobajić S, Stanković I, Đorđević B. Prevalence rates and trends on underweight, normal weight and overweight/obesity among pharmacy student population in Serbia. in Annals of Nutrition and Metabolism. 2007;51(suppl 1):302-302.
doi:10.1159/000105121 .

Konić-Ristić, Aleksandra, Vidović, Bojana, Šobajić, Slađana, Stanković, Ivan, Đorđević, Brižita, "Prevalence rates and trends on underweight, normal weight and overweight/obesity among pharmacy student population in Serbia" in Annals of Nutrition and Metabolism, 51, no. suppl 1 (2007):302-302,
https://doi.org/10.1159/000105121 . .

TY  - JOUR
AU  - Cerović, Aleksandra
AU  - Miletić, Ivanka
AU  - Konić-Ristić, Aleksandra
AU  - Baralić, Ivana
AU  - Đorđević, Brižita
AU  - Đuričić, Ivana
AU  - Radusinović, M
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/869
AB  - The aim of present study was to assess the effects and safety of a dry Phaseoli vulgari pericarpium (PVP) extract on postprandial glycemia in healthy participants. A randomized crossover experiment where participants received either PVP extract or placebo. Chemical compounds in dry extract were assessed by established methods. Eighteen healthy participants (9 male and 9 female) aged 29+/-4,8 years, body mass index (BMI) 23+/-3,7 kg/m(2) were recruited among students and staff at the Faculty of Pharmacy, University of Belgrade. All participants were able to follow the study protocol without difficulty. The participants received either PVP extract or placebo 30 minutes before a 50g oral glucose tolerance test (OGTT). The protocol followed the guidelines for the OGTT with blood samples drawn at 0, 15, 30, 60, 90 and 120 min. This study demonstrated that there was no significantly effect of the PVP extract on incremental blood glucose (IBG) and their areas under the curve (AUC) neither male nor female participants. However, IBG together with AUC changes were significantly lower in male compared with female participants in treated and untreated groups. The presence of chrome, soluble fiber, vitamin C, protein, glucose and lectins were also quantified. The applied amount of PVP extract was unable to produce the postprandial hypoglycemia. We assumed that amounts of chrome, soluble fiber, vitamin C which have beneficial effects on diabetes treatment were sufficient to produce hypoglycemia.
PB  - Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
T2  - Bosnian Journal of Basic Medical Sciences
T1  - The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.
VL  - 6
IS  - 3
SP  - 28
EP  - 33
UR  - https://hdl.handle.net/21.15107/rcub_farfar_869
ER  - 

@article{
author = "Cerović, Aleksandra and Miletić, Ivanka and Konić-Ristić, Aleksandra and Baralić, Ivana and Đorđević, Brižita and Đuričić, Ivana and Radusinović, M",
year = "2006",
abstract = "The aim of present study was to assess the effects and safety of a dry Phaseoli vulgari pericarpium (PVP) extract on postprandial glycemia in healthy participants. A randomized crossover experiment where participants received either PVP extract or placebo. Chemical compounds in dry extract were assessed by established methods. Eighteen healthy participants (9 male and 9 female) aged 29+/-4,8 years, body mass index (BMI) 23+/-3,7 kg/m(2) were recruited among students and staff at the Faculty of Pharmacy, University of Belgrade. All participants were able to follow the study protocol without difficulty. The participants received either PVP extract or placebo 30 minutes before a 50g oral glucose tolerance test (OGTT). The protocol followed the guidelines for the OGTT with blood samples drawn at 0, 15, 30, 60, 90 and 120 min. This study demonstrated that there was no significantly effect of the PVP extract on incremental blood glucose (IBG) and their areas under the curve (AUC) neither male nor female participants. However, IBG together with AUC changes were significantly lower in male compared with female participants in treated and untreated groups. The presence of chrome, soluble fiber, vitamin C, protein, glucose and lectins were also quantified. The applied amount of PVP extract was unable to produce the postprandial hypoglycemia. We assumed that amounts of chrome, soluble fiber, vitamin C which have beneficial effects on diabetes treatment were sufficient to produce hypoglycemia.",
publisher = "Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina",
journal = "Bosnian Journal of Basic Medical Sciences",
title = "The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.",
volume = "6",
number = "3",
pages = "28-33",
url = "https://hdl.handle.net/21.15107/rcub_farfar_869"
}

Cerović, A., Miletić, I., Konić-Ristić, A., Baralić, I., Đorđević, B., Đuričić, I.,& Radusinović, M.. (2006). The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.. in Bosnian Journal of Basic Medical Sciences
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina., 6(3), 28-33.
https://hdl.handle.net/21.15107/rcub_farfar_869

Cerović A, Miletić I, Konić-Ristić A, Baralić I, Đorđević B, Đuričić I, Radusinović M. The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject.. in Bosnian Journal of Basic Medical Sciences. 2006;6(3):28-33.
https://hdl.handle.net/21.15107/rcub_farfar_869 .

Cerović, Aleksandra, Miletić, Ivanka, Konić-Ristić, Aleksandra, Baralić, Ivana, Đorđević, Brižita, Đuričić, Ivana, Radusinović, M, "The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject." in Bosnian Journal of Basic Medical Sciences, 6, no. 3 (2006):28-33,
https://hdl.handle.net/21.15107/rcub_farfar_869 .

TY  - JOUR
AU  - Miletić, Ivanka
AU  - Konić-Ristić, Aleksandra
AU  - Đorđević, Brižita
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/743
AB  - Nutritional needs of all pregnant women depend on the stage of maternal growth and development and pregnancy nutritional status. In general, pregnancy increases a women's total daily energy requirements by an average of 15%. A lactating women needs an additional energy intake per day. Protein requirements increase to provide essential amino acides for fetal development, blood volume expansion and growth of maternal tissues. Protein requirements increase during lactation because protein is an important component in breast milk. Requirements of lipids, during pregnancy, depending on caloric intake, and carbohydrates requirements increase during the second and third trimesters. Pregnancy and lactation increases the need for all water-soluble vitamins and fat-soluble vitamins as well ( vitamin D must be taken very carefully). Requirements for minerals as calcium, phosphorus, zinc, magnesium, iodine and iron increase during pregnancy and lactation too.
AB  - Period trudnoće i dojenja čini posebno stanje mladih, zdravih osoba ženskog pola u kojem je dizajniranje optimalne dijete od posebnog značaja, kako za buduću majku, tako i za dete. Bitni faktori koji utiču na dizajniranje optimalne dijete tokom trudnoće i dojenja uključuju godine starosti, način života, kulturu, okruženje, edukaciju, ali i ekonomski status. Generalno, u periodu trudnoće povećavaju se potrebe žene za unosom energetskih materija hranom i do 15 %. Tokom dojenja potrebe unosa energetskih nutrimenata se i dalje povećavaju. Period trudnoće obeležen je i povećanim unosom proteina u cilju snabdevanja organizma esencijelnim aminokiselinama koje su neophodne za razvoj fetusa, povećanje zapremine krvi i za rast specifičnih tkiva. Period dojenja takođe prati povećan unos proteina, jer proteini čine značajnu komponentu mleka majke. Potrebe unosa lipida, tokom trudnoće, prate energetski unos. Lipidi su značajan izvor neophodnih ω-3 i ω6 esencijelnih masnih kiselina. Povećane potrebe za ugljenim hidratima su posebno izražene tokom drugog i trećeg trimestra. U periodu kako trudnoće tako i dojenja potrebno je povećano unositi sve hidrosolubilne i liposolubilne vitamine. Potrebno je naglasiti da unos vitamina D bude pod kontrolom. Potrebe za mineralnim materijama, kao što su kalcijum. fosfor, cink, magnezijum, jod i gvožđe takođe se povećavaju tokom trudnoće i dojenja.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Optimal diet during pregnancy and lactation
T1  - Optimalna dijeta tokom trudnoće i dojenja
VL  - 56
IS  - 3
SP  - 252
EP  - 260
UR  - https://hdl.handle.net/21.15107/rcub_farfar_743
ER  - 

@article{
author = "Miletić, Ivanka and Konić-Ristić, Aleksandra and Đorđević, Brižita",
year = "2006",
abstract = "Nutritional needs of all pregnant women depend on the stage of maternal growth and development and pregnancy nutritional status. In general, pregnancy increases a women's total daily energy requirements by an average of 15%. A lactating women needs an additional energy intake per day. Protein requirements increase to provide essential amino acides for fetal development, blood volume expansion and growth of maternal tissues. Protein requirements increase during lactation because protein is an important component in breast milk. Requirements of lipids, during pregnancy, depending on caloric intake, and carbohydrates requirements increase during the second and third trimesters. Pregnancy and lactation increases the need for all water-soluble vitamins and fat-soluble vitamins as well ( vitamin D must be taken very carefully). Requirements for minerals as calcium, phosphorus, zinc, magnesium, iodine and iron increase during pregnancy and lactation too., Period trudnoće i dojenja čini posebno stanje mladih, zdravih osoba ženskog pola u kojem je dizajniranje optimalne dijete od posebnog značaja, kako za buduću majku, tako i za dete. Bitni faktori koji utiču na dizajniranje optimalne dijete tokom trudnoće i dojenja uključuju godine starosti, način života, kulturu, okruženje, edukaciju, ali i ekonomski status. Generalno, u periodu trudnoće povećavaju se potrebe žene za unosom energetskih materija hranom i do 15 %. Tokom dojenja potrebe unosa energetskih nutrimenata se i dalje povećavaju. Period trudnoće obeležen je i povećanim unosom proteina u cilju snabdevanja organizma esencijelnim aminokiselinama koje su neophodne za razvoj fetusa, povećanje zapremine krvi i za rast specifičnih tkiva. Period dojenja takođe prati povećan unos proteina, jer proteini čine značajnu komponentu mleka majke. Potrebe unosa lipida, tokom trudnoće, prate energetski unos. Lipidi su značajan izvor neophodnih ω-3 i ω6 esencijelnih masnih kiselina. Povećane potrebe za ugljenim hidratima su posebno izražene tokom drugog i trećeg trimestra. U periodu kako trudnoće tako i dojenja potrebno je povećano unositi sve hidrosolubilne i liposolubilne vitamine. Potrebno je naglasiti da unos vitamina D bude pod kontrolom. Potrebe za mineralnim materijama, kao što su kalcijum. fosfor, cink, magnezijum, jod i gvožđe takođe se povećavaju tokom trudnoće i dojenja.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Optimal diet during pregnancy and lactation, Optimalna dijeta tokom trudnoće i dojenja",
volume = "56",
number = "3",
pages = "252-260",
url = "https://hdl.handle.net/21.15107/rcub_farfar_743"
}

Miletić, I., Konić-Ristić, A.,& Đorđević, B.. (2006). Optimal diet during pregnancy and lactation. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 56(3), 252-260.
https://hdl.handle.net/21.15107/rcub_farfar_743

Miletić I, Konić-Ristić A, Đorđević B. Optimal diet during pregnancy and lactation. in Arhiv za farmaciju. 2006;56(3):252-260.
https://hdl.handle.net/21.15107/rcub_farfar_743 .

Miletić, Ivanka, Konić-Ristić, Aleksandra, Đorđević, Brižita, "Optimal diet during pregnancy and lactation" in Arhiv za farmaciju, 56, no. 3 (2006):252-260,
https://hdl.handle.net/21.15107/rcub_farfar_743 .

TY  - CONF
AU  - Konić-Ristić, Aleksandra
AU  - Stanković, Ivan
AU  - Juranić, Zorica
AU  - Stanojković, Tatjana
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/767
PB  - Savez farmaceutskih udruženja Srbije, Beograd
C3  - Arhiv za farmaciju
T1  - Antiproliferative action of dietary isothiocyanates on cancer cells in vitro
T1  - Antiproliferativno delovanje dijetarnih izotiocijanata na malignim ćelijskim linijama in vitro
VL  - 56
IS  - 4
SP  - 576
EP  - 577
UR  - https://hdl.handle.net/21.15107/rcub_farfar_767
ER  - 

@conference{
author = "Konić-Ristić, Aleksandra and Stanković, Ivan and Juranić, Zorica and Stanojković, Tatjana",
year = "2006",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Antiproliferative action of dietary isothiocyanates on cancer cells in vitro, Antiproliferativno delovanje dijetarnih izotiocijanata na malignim ćelijskim linijama in vitro",
volume = "56",
number = "4",
pages = "576-577",
url = "https://hdl.handle.net/21.15107/rcub_farfar_767"
}

Konić-Ristić, A., Stanković, I., Juranić, Z.,& Stanojković, T.. (2006). Antiproliferative action of dietary isothiocyanates on cancer cells in vitro. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 56(4), 576-577.
https://hdl.handle.net/21.15107/rcub_farfar_767

Konić-Ristić A, Stanković I, Juranić Z, Stanojković T. Antiproliferative action of dietary isothiocyanates on cancer cells in vitro. in Arhiv za farmaciju. 2006;56(4):576-577.
https://hdl.handle.net/21.15107/rcub_farfar_767 .

Konić-Ristić, Aleksandra, Stanković, Ivan, Juranić, Zorica, Stanojković, Tatjana, "Antiproliferative action of dietary isothiocyanates on cancer cells in vitro" in Arhiv za farmaciju, 56, no. 4 (2006):576-577,
https://hdl.handle.net/21.15107/rcub_farfar_767 .

TY  - JOUR
AU  - Miletić, Ivanka
AU  - Konić-Ristić, Aleksandra
AU  - Đorđević, Brižita
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/568
AB  - Growth is associated with increases in weight, development indicates the progressive changes in tissues and organs functions. Nutritional factors during early development have short-term effects on growth but also exert longer-term effects. Dietetic foods are intended to satisfy particular nutritional requirements of specific groups of populations. The foodstuffs intended to satisfy the nutritional requirements of infants and young children are dietetic foods for infants and young children including infant formulae and follow-on formulae.
AB  - Rast i razvoj deteta su asocirani procesi, dešavaju se paralelno i zajedno čine deo kvalitetnih promena mladog organizma. Kako će se, u ovako osetljivom periodu, odvijati svi procesi zavisi i od hrane koja se konzumira, odnosno da li se svi neophodni nutrimenti unose u pravo vreme u potrebnim količinama. Dijetetska hrana koja je namenjena bebama i maloj deci obuhvata infant formule, follow on formule i hranu za malu decu. Sve komponente koje se dodaju dijetetskoj hrani moraju biti strogo kontrolisane pozitivnim listama određenih direktiva.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
T2  - Arhiv za farmaciju
T1  - Dietetic foods for infants and young children
T1  - Dijetetska hrana namenjena bebama i maloj deci
VL  - 55
IS  - 4
SP  - 329
EP  - 337
UR  - https://hdl.handle.net/21.15107/rcub_farfar_568
ER  - 

@article{
author = "Miletić, Ivanka and Konić-Ristić, Aleksandra and Đorđević, Brižita",
year = "2005",
abstract = "Growth is associated with increases in weight, development indicates the progressive changes in tissues and organs functions. Nutritional factors during early development have short-term effects on growth but also exert longer-term effects. Dietetic foods are intended to satisfy particular nutritional requirements of specific groups of populations. The foodstuffs intended to satisfy the nutritional requirements of infants and young children are dietetic foods for infants and young children including infant formulae and follow-on formulae., Rast i razvoj deteta su asocirani procesi, dešavaju se paralelno i zajedno čine deo kvalitetnih promena mladog organizma. Kako će se, u ovako osetljivom periodu, odvijati svi procesi zavisi i od hrane koja se konzumira, odnosno da li se svi neophodni nutrimenti unose u pravo vreme u potrebnim količinama. Dijetetska hrana koja je namenjena bebama i maloj deci obuhvata infant formule, follow on formule i hranu za malu decu. Sve komponente koje se dodaju dijetetskoj hrani moraju biti strogo kontrolisane pozitivnim listama određenih direktiva.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Dietetic foods for infants and young children, Dijetetska hrana namenjena bebama i maloj deci",
volume = "55",
number = "4",
pages = "329-337",
url = "https://hdl.handle.net/21.15107/rcub_farfar_568"
}

Miletić, I., Konić-Ristić, A.,& Đorđević, B.. (2005). Dietetic foods for infants and young children. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 55(4), 329-337.
https://hdl.handle.net/21.15107/rcub_farfar_568

Miletić I, Konić-Ristić A, Đorđević B. Dietetic foods for infants and young children. in Arhiv za farmaciju. 2005;55(4):329-337.
https://hdl.handle.net/21.15107/rcub_farfar_568 .

Miletić, Ivanka, Konić-Ristić, Aleksandra, Đorđević, Brižita, "Dietetic foods for infants and young children" in Arhiv za farmaciju, 55, no. 4 (2005):329-337,
https://hdl.handle.net/21.15107/rcub_farfar_568 .

TY  - JOUR
AU  - Konić-Ristić, Aleksandra
AU  - Šobajić, Slađana
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/640
AB  - Sulphiting agents have been used in food production for centuries. Sulphites are added to food as antimicrobial, antibrowning agents or antioxidants. Their use became an issue of concern when certain sensitive individuals exhibited adverse reactions to sulphite residues in foods. Sulphites also exert a number of different anti-nutritive effects. Like other ingredients, sulfites must be declared in the ingredient statement. Among all sulphite-containing foods, the highest contributors to the dietary intake are dried fruits and wine. The aim of this work was to determine residual levels of total sulphur dioxide in dried fruit samples in order to examine the risk of exceeding the Acceptable Daily Intake (ADI) for sulphites by consuming this type of food. The other scope of the study was to investigate compliance with food labeling in order to insure consumer protection. The determination was performed on all samples by colorimetric para-rosaniline method, according to the official method of analysis of AOAC 963.20 (AOAC 2002).Twelve different samples of dried fruit were analyzed. Results showed that dried fruit is very rich source of sulphites. The range of residual sulphur-dioxide was very large, from nondetectable levels (in three samples) to 1847.3 mgSO2/kg. In ten of twelve samples SO2 levels were under national Maximum Permitted Level (MPL). SO2 content was above MPL in dried bananas sample and dried sweet coconut. Just eight of twelve fruit samples had label declarations of sulfite content but the determined levels of sulfites were significantly above the declared levels.
AB  - Sulfiti se u različitim hemijskim formama koriste vekovima kao aditivi u proizvodnji hrane. Oni imaju antimikrobno delovanje, koriste se za sprečavanje enzimskog i neenzimskog tamnjenja namirnica i kao antioksidansi. Mogu se javiti i kao prirodni sastojci namirnica. Primenu sulfita kao aditiva ograničava činjenica da konzumiranje hrane koja sadrži sulfite kod određenog broja astmatičara dovodi do pogoršanja simptoma. Veliki broj namirnica sadrži sulfite, ali se smatra da najveći doprinos dnevnom unosu daju vino i suvo voće. Cilj ovog rada je određivanje rezidualnog sumpor-dioksida u uzorcima suvog voća sa beogradskog tržišta. Određivanje je urađeno oficijelnom kolorimetrijskom metodom sa p-rozanilin hidrohloridom AOAC 963.20 (AOAC 2002). Rezultati su pokazali da je suvo voće značajan izvor sulfita i nivo rezidualnog sulfita se kretao od nedektibilnih vrednosti do 1847.3 mg SO2/kg. U dva od analiziranih dvanaest uzoraka, nivo rezidualnog sumpor-dioksida prevazilazio je propisane MDK vrednosti za ove vrste uzoraka. Osam uzoraka suvog voća je imalo deklarisan sadržaj SO2 ali su nadene vrednosti bile znatno veće od deklarisanih. S obzirom na redovnu upotrebu sulfita u proizvodnji suvog voća, može se zaključiti da je neophodno da proizvođači hrane, posebno prerađevina od voća, imaju razvijen sistem kontrole nivoa sulfita u proizvodima koji ce se naći na tržištu kao i obavezu da u saglasnosti sa važećim propisima, prisustvo sulfita bude deklarisano.
PB  - Društvo za ishranu Srbije, Beograd
T2  - Hrana i ishrana
T1  - Residual levels of total sulphur dioxide in dried fruit samples from Belgrade market
T1  - Rezidualni sumpor-dioksid u uzorcima suvog voća sa beogradskog tržišta
VL  - 46
IS  - 3-4
SP  - 51
EP  - 55
UR  - https://hdl.handle.net/21.15107/rcub_farfar_640
ER  - 

@article{
author = "Konić-Ristić, Aleksandra and Šobajić, Slađana",
year = "2005",
abstract = "Sulphiting agents have been used in food production for centuries. Sulphites are added to food as antimicrobial, antibrowning agents or antioxidants. Their use became an issue of concern when certain sensitive individuals exhibited adverse reactions to sulphite residues in foods. Sulphites also exert a number of different anti-nutritive effects. Like other ingredients, sulfites must be declared in the ingredient statement. Among all sulphite-containing foods, the highest contributors to the dietary intake are dried fruits and wine. The aim of this work was to determine residual levels of total sulphur dioxide in dried fruit samples in order to examine the risk of exceeding the Acceptable Daily Intake (ADI) for sulphites by consuming this type of food. The other scope of the study was to investigate compliance with food labeling in order to insure consumer protection. The determination was performed on all samples by colorimetric para-rosaniline method, according to the official method of analysis of AOAC 963.20 (AOAC 2002).Twelve different samples of dried fruit were analyzed. Results showed that dried fruit is very rich source of sulphites. The range of residual sulphur-dioxide was very large, from nondetectable levels (in three samples) to 1847.3 mgSO2/kg. In ten of twelve samples SO2 levels were under national Maximum Permitted Level (MPL). SO2 content was above MPL in dried bananas sample and dried sweet coconut. Just eight of twelve fruit samples had label declarations of sulfite content but the determined levels of sulfites were significantly above the declared levels., Sulfiti se u različitim hemijskim formama koriste vekovima kao aditivi u proizvodnji hrane. Oni imaju antimikrobno delovanje, koriste se za sprečavanje enzimskog i neenzimskog tamnjenja namirnica i kao antioksidansi. Mogu se javiti i kao prirodni sastojci namirnica. Primenu sulfita kao aditiva ograničava činjenica da konzumiranje hrane koja sadrži sulfite kod određenog broja astmatičara dovodi do pogoršanja simptoma. Veliki broj namirnica sadrži sulfite, ali se smatra da najveći doprinos dnevnom unosu daju vino i suvo voće. Cilj ovog rada je određivanje rezidualnog sumpor-dioksida u uzorcima suvog voća sa beogradskog tržišta. Određivanje je urađeno oficijelnom kolorimetrijskom metodom sa p-rozanilin hidrohloridom AOAC 963.20 (AOAC 2002). Rezultati su pokazali da je suvo voće značajan izvor sulfita i nivo rezidualnog sulfita se kretao od nedektibilnih vrednosti do 1847.3 mg SO2/kg. U dva od analiziranih dvanaest uzoraka, nivo rezidualnog sumpor-dioksida prevazilazio je propisane MDK vrednosti za ove vrste uzoraka. Osam uzoraka suvog voća je imalo deklarisan sadržaj SO2 ali su nadene vrednosti bile znatno veće od deklarisanih. S obzirom na redovnu upotrebu sulfita u proizvodnji suvog voća, može se zaključiti da je neophodno da proizvođači hrane, posebno prerađevina od voća, imaju razvijen sistem kontrole nivoa sulfita u proizvodima koji ce se naći na tržištu kao i obavezu da u saglasnosti sa važećim propisima, prisustvo sulfita bude deklarisano.",
publisher = "Društvo za ishranu Srbije, Beograd",
journal = "Hrana i ishrana",
title = "Residual levels of total sulphur dioxide in dried fruit samples from Belgrade market, Rezidualni sumpor-dioksid u uzorcima suvog voća sa beogradskog tržišta",
volume = "46",
number = "3-4",
pages = "51-55",
url = "https://hdl.handle.net/21.15107/rcub_farfar_640"
}

Konić-Ristić, A.,& Šobajić, S.. (2005). Residual levels of total sulphur dioxide in dried fruit samples from Belgrade market. in Hrana i ishrana
Društvo za ishranu Srbije, Beograd., 46(3-4), 51-55.
https://hdl.handle.net/21.15107/rcub_farfar_640

Konić-Ristić A, Šobajić S. Residual levels of total sulphur dioxide in dried fruit samples from Belgrade market. in Hrana i ishrana. 2005;46(3-4):51-55.
https://hdl.handle.net/21.15107/rcub_farfar_640 .

Konić-Ristić, Aleksandra, Šobajić, Slađana, "Residual levels of total sulphur dioxide in dried fruit samples from Belgrade market" in Hrana i ishrana, 46, no. 3-4 (2005):51-55,
https://hdl.handle.net/21.15107/rcub_farfar_640 .