TY  - CONF
AU  - Popović-Nikolić, Marija
AU  - Popović, Gordana
AU  - Berdon, Katarina
PY  - 2018
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5183
AB  - The pKa values of ciprofloxacin (CPF) and norfloxacin (NRF) were
determined potentiometrically, with and without the presence of differently
charged micelles, as biomembrane mimetic models. The shift in protolytic
equilibria are observed in the presence of surfactants, SDS (ΔpKa1 = +2.02;
ΔpKa2 = +0.57); CTAB (ΔpKa1 = -0.09; ΔpKa2 = -0.23) and TX-100 (ΔpKa1 =
+0.24; ΔpKa2 = +0.29). The change in distribution of equilibrium forms is
most expressed in pH range 6 – 8 which may indicate on potential interactions
with molecules of different polarity and charge under physiological
conditions.
PB  - Society of Physical Chemists of Serbia
C3  - Physical Chemistry 2018 (Proceedings) 14th International Conference on Fundamental and Applied Aspects of Physical Chemistry
T1  - The ionization of fluoroquinolones in the presence of differently charged surfactants
VL  - II
SP  - 967
EP  - 970
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5183
ER  - 

@conference{
author = "Popović-Nikolić, Marija and Popović, Gordana and Berdon, Katarina",
year = "2018",
abstract = "The pKa values of ciprofloxacin (CPF) and norfloxacin (NRF) were
determined potentiometrically, with and without the presence of differently
charged micelles, as biomembrane mimetic models. The shift in protolytic
equilibria are observed in the presence of surfactants, SDS (ΔpKa1 = +2.02;
ΔpKa2 = +0.57); CTAB (ΔpKa1 = -0.09; ΔpKa2 = -0.23) and TX-100 (ΔpKa1 =
+0.24; ΔpKa2 = +0.29). The change in distribution of equilibrium forms is
most expressed in pH range 6 – 8 which may indicate on potential interactions
with molecules of different polarity and charge under physiological
conditions.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical Chemistry 2018 (Proceedings) 14th International Conference on Fundamental and Applied Aspects of Physical Chemistry",
title = "The ionization of fluoroquinolones in the presence of differently charged surfactants",
volume = "II",
pages = "967-970",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5183"
}

Popović-Nikolić, M., Popović, G.,& Berdon, K.. (2018). The ionization of fluoroquinolones in the presence of differently charged surfactants. in Physical Chemistry 2018 (Proceedings) 14th International Conference on Fundamental and Applied Aspects of Physical Chemistry
Society of Physical Chemists of Serbia., II, 967-970.
https://hdl.handle.net/21.15107/rcub_farfar_5183

Popović-Nikolić M, Popović G, Berdon K. The ionization of fluoroquinolones in the presence of differently charged surfactants. in Physical Chemistry 2018 (Proceedings) 14th International Conference on Fundamental and Applied Aspects of Physical Chemistry. 2018;II:967-970.
https://hdl.handle.net/21.15107/rcub_farfar_5183 .

Popović-Nikolić, Marija, Popović, Gordana, Berdon, Katarina, "The ionization of fluoroquinolones in the presence of differently charged surfactants" in Physical Chemistry 2018 (Proceedings) 14th International Conference on Fundamental and Applied Aspects of Physical Chemistry, II (2018):967-970,
https://hdl.handle.net/21.15107/rcub_farfar_5183 .