Ecophysiological and genetic investigations of domestic animals and bees for the purpose of increasing reproductive traits and disease resistance

Link to this page

http://farfar.pharmacy.bg.ac.rs/APP/faces/project.xhtml?project_id=info%3Aeu-repo%2FgrantAgreement%2FMESTD%2FMPN2006-2010%2F143022%2FRS%2F%2F&item_offset=0&author_offset=0&sort_by=dc.date.issued

info:eu-repo/grantAgreement/MESTD/MPN2006-2010/143022/RS//

Ecophysiological and genetic investigations of domestic animals and bees for the purpose of increasing reproductive traits and disease resistance (en)
Екофизиолошка и генетичка истраживања домаћих животиња и пчела у функцији повећања репродуктивних својстава и отпорности на болести (sr)
Ekofiziološka i genetička istraživanja domaćih životinja i pčela u funkciji povećanja reproduktivnih svojstava i otpornosti na bolesti (sr_RS)
Authors

Publications

The effect of paclitaxel alone and in combination with cycloheximide on the frequency of premature centromere division in vitro

Bajić, Vladan; Stanimirović, Zoran; Stevanović, Jevrosima; Milićević, Zorka; Živković, Lada; Potparević, Biljana

(Srpsko biološko društvo, Beograd, i dr., 2010) 

TY  - JOUR
AU  - Bajić, Vladan
AU  - Stanimirović, Zoran
AU  - Stevanović, Jevrosima
AU  - Milićević, Zorka
AU  - Živković, Lada
AU  - Potparević, Biljana
PY  - 2010
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1433
AB  - Premature centromere division (PCD) can be viewed as a manifestation of chromosome instability. In order to evaluate the ability of Paclitaxel (Ptx) and Cycloheximide (Cy) to induce PCD we used a cytokinesis block micronucleus assay (CBMN), fluorescent in situ hybridization (FISH), and the chromosome aberration (CA) assay in human peripheral blood lymphocytes. Results showed that Ptx can induce PCD alone or in combination with Cy. These findings call us to pay more attention to PCD as a parameter of genotoxicity in the pre-clinical research of mono and/or combinational therapies for cancer treatment.
AB  - Prevremena centromerna deoba (PCD) se može posmatrati kao manifestacija hromozomske nestabilnosti. U cilju procene efekta paklitaksela (Ptx) i cikloheksimida (Cy) na indukciju PCD-a, koristili smo mikronukleus test (CBMN) uz fluorescentnu in situ hibridizaciju (FISH), kao i test hromozomskih aberacija (CA) na humanim limfocitima periferne krvi. Rezultati su pokazali da Ptx sam, ili u kombinaciji sa Cy može da indukuje PCD. Ovi nalazi ukazuju da treba mnogo više pažnje obratiti na pojavu PCD-a kao parametra genotoksičnosti u prekliničkim ispitivanjima mono- i/ili politerapija za lečenje kancera.
PB  - Srpsko biološko društvo, Beograd, i dr.
T2  - Archives of Biological Sciences
T1  - The effect of paclitaxel alone and in combination with cycloheximide on the frequency of premature centromere division in vitro
T1  - Efekat samog paklitaksela, i u kombinaciji sa cikloheksimidom, na učestalost prevremene centromerne deobe in vitro
VL  - 62
IS  - 1
SP  - 63
EP  - 74
DO  - 10.2298/ABS1001063B
ER  - 
@article{
author = "Bajić, Vladan and Stanimirović, Zoran and Stevanović, Jevrosima and Milićević, Zorka and Živković, Lada and Potparević, Biljana",
year = "2010",
abstract = "Premature centromere division (PCD) can be viewed as a manifestation of chromosome instability. In order to evaluate the ability of Paclitaxel (Ptx) and Cycloheximide (Cy) to induce PCD we used a cytokinesis block micronucleus assay (CBMN), fluorescent in situ hybridization (FISH), and the chromosome aberration (CA) assay in human peripheral blood lymphocytes. Results showed that Ptx can induce PCD alone or in combination with Cy. These findings call us to pay more attention to PCD as a parameter of genotoxicity in the pre-clinical research of mono and/or combinational therapies for cancer treatment., Prevremena centromerna deoba (PCD) se može posmatrati kao manifestacija hromozomske nestabilnosti. U cilju procene efekta paklitaksela (Ptx) i cikloheksimida (Cy) na indukciju PCD-a, koristili smo mikronukleus test (CBMN) uz fluorescentnu in situ hibridizaciju (FISH), kao i test hromozomskih aberacija (CA) na humanim limfocitima periferne krvi. Rezultati su pokazali da Ptx sam, ili u kombinaciji sa Cy može da indukuje PCD. Ovi nalazi ukazuju da treba mnogo više pažnje obratiti na pojavu PCD-a kao parametra genotoksičnosti u prekliničkim ispitivanjima mono- i/ili politerapija za lečenje kancera.",
publisher = "Srpsko biološko društvo, Beograd, i dr.",
journal = "Archives of Biological Sciences",
title = "The effect of paclitaxel alone and in combination with cycloheximide on the frequency of premature centromere division in vitro, Efekat samog paklitaksela, i u kombinaciji sa cikloheksimidom, na učestalost prevremene centromerne deobe in vitro",
volume = "62",
number = "1",
pages = "63-74",
doi = "10.2298/ABS1001063B"
}
Bajić, V., Stanimirović, Z., Stevanović, J., Milićević, Z., Živković, L.,& Potparević, B.. (2010). The effect of paclitaxel alone and in combination with cycloheximide on the frequency of premature centromere division in vitro. in Archives of Biological Sciences
Srpsko biološko društvo, Beograd, i dr.., 62(1), 63-74.
https://doi.org/10.2298/ABS1001063B
Bajić V, Stanimirović Z, Stevanović J, Milićević Z, Živković L, Potparević B. The effect of paclitaxel alone and in combination with cycloheximide on the frequency of premature centromere division in vitro. in Archives of Biological Sciences. 2010;62(1):63-74.
doi:10.2298/ABS1001063B .
Bajić, Vladan, Stanimirović, Zoran, Stevanović, Jevrosima, Milićević, Zorka, Živković, Lada, Potparević, Biljana, "The effect of paclitaxel alone and in combination with cycloheximide on the frequency of premature centromere division in vitro" in Archives of Biological Sciences, 62, no. 1 (2010):63-74,
https://doi.org/10.2298/ABS1001063B . .
3
2
1
2