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Утицај смеше токсичних метал(оид)а на NRF2 сигналне путеве у јетри и бубрезима пацова / The effect of toxic metal(oid)s mixture on NRF2 signaling pathways in liver and kidneys of rats
(2023)
Tоксиколошкe студијe углавном се баве испитивањем токсичности појединачних метала, што не одражава реално животно окружење. На основу студије хуманог биомониторинга одабрано је 6 токсичних метал(оид)а (As, Pb, Hg, Cd, Cr ...
About the HPV vaccine: how it works and who can get it
(Komora magistara farmacije Federacije Bosne i hercegovineFarmaceutska komora Republike SrpskeFarmaceutsko društvo Republike Srpske, 2023)
Human papilloma viruses (HPV) are small non-enveloped DNA viruses that posses
great affinity for epithelial tissue. So far, more than 200 genotypes of HPV have been
identified, of which around 40 types are associated ...
Probiotic cultures as a potential protective strategy against the toxicity of environmentally relevant chemicals: State-of-the-art knowledge
(Elsevier Ltd, 2023)
Environmentally relevant toxic substances may affect human health, provoking numerous harmful effects on central nervous, respiratory, cardiovascular, endocrine and reproductive system, and even cause various types of ...
COVID-19 signalome: Potential therapeutic interventions
(Elsevier Inc., 2023)
The COVID-19 pandemic has triggered intensive research and development of drugs and vaccines against SARS-CoV-2 during the last two years. The major success was especially observed with development of vaccines based on ...
Encapsulation of cannabidiol in oil-in-water nanoemulsions and nanoemulsion-filled hydrogels: A structure and biological assessment study
(Academic Press Inc., 2023)
Hypothesis: Lipophilic cannabidiol can be solubilized in oil-in water nanoemulsions, which can then be impregnated into chitosan hydrogels forming another colloidal system that will facilitate cannabidiol's release. The ...
Промена генске експресије ензима антиоксидативне заштите и адипонектинских рецептора у адипоцитима субкутаног масног ткива након терапије гојазности интрагастричним балоном / Changes of antioxidant enzymes and adiponectin receptors gene expressions levels in subcutaneous adipose tissue adipocytes following intragastric balloon therapy for obesity
(2023)
Гојазност је мултифакторска болест која представља ризик по здравље. Један од видова терапије гојазности је уградња интрагастричног балона. Адипозно ткиво (АТ) није само орган за складиштење триглицерида, већ активно ...
In silico assessment of intestinal precipitation: Case study of a poorly soluble, weakly basic compound
(Macedonian Pharmaceutical AssociationSs. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2023)
Precipitation of a drug substance in the small intestine
is a phenomenon relevant to weak bases due to their pH-
dependent solubility. Because of the low solubility at
higher pH, upon entry in the small intestine, a ...
Integration of epigenetic regulatory mechanisms in heart failure
(Springer Science and Business Media Deutschland GmbH, 2023)
The number of “omics” approaches is continuously growing. Among others, epigenetics has appeared as an attractive area of investigation by the cardiovascular research community, notably considering its association with ...
Analytical Quality by Design: Achieving Robustness of an LC-CAD Method for the Analysis of Non-Volatile Fatty Acids
(MDPI, 2023)
An alternative to the time-consuming and error-prone pharmacopoeial gas chromatography method for the analysis of fatty acids (FAs) is urgently needed. The objective was therefore to propose a robust liquid chromatography ...
Cadmium and lead implication in testis cancer; is there a connection?
(Elsevier Ltd, 2023)
Testis cancer (TC) is the most common malignancy of young men. Current evidence from studies, alongside genetics and hormonal status, suggests a significant role of toxic metals, cadmium (Cd) and lead (Pb), in the origin ...