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DNA Damage in Alzheimer Disease Lymphocytes and Its Relation to Premature Centromere Division
(Karger, Basel, 2013)
While Alzheimer disease (AD) is considered a neurodegenerative disorder, the importance of chromosome instability in non-neuronal cells is equally important, not only for shedding light on the etiology of the disease, but ...
Unexpected effect of dry olive leaf extract on the level of DNA damage in lymphocytes of lead intoxicated workers, before and after CaNa(2)EDTA chelation therapy
(Pergamon-Elsevier Science Ltd, Oxford, 2017)
The CaNa(2)EDTA chelation therapy is often practiced with antioxidant supplementation. Dry olive leaf extract (DOLE) is natural product with antioxidant and DNA protective properties. The effects of DOLE on the levels of ...
Evaluation of cytogenetic and DNA damage in human lymphocytes treated with adrenaline in vitro
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Catechol groups can be involved in redox cycling accompanied by generation of reactive oxygen species (ROS) which may lead to oxidative damage of cellular macromolecules including DNA. The objective of this investigation ...
Nepeta rtanjensis (Lamiaceae), a plant endemic to the Balkans: Phenolic composition antioxidant activity, and in vitro antigenotoxic effects in triiodothyronine-induced DNA damage in human lymphocytes
(Univ Karachi, Karachi, 2017)
The success of antioxidant therapy in hyperthyroidism implies that disease is mediated by oxidative stress, which is known as one of the causing agents of agemg, degenerative diseases, and cancer. The main objective of our ...
Evaluation of antigenotoxic potential of salvianolic acid B with hydrogen peroxide on human peripheral blood leukocytes in vitro / Evaluacija antigenotoksičnog potencijala salvianolične kiseline B u prisustvu vodonik-peroksida na leukocitima periferne krvi in vitro
(Srpsko lekarsko društvo - Okružna podružnica Kragujevac, Kragujevac, 2017)
Aim. Oxidative stress is a consequence of the increased production of free radicals that is caused by the disturbance in the balance of oxidation-reduction activity. Salvianolic acid B is a polyphenol compound, derived ...
Olive Leaf Extract Attenuates Inflammatory Activation and DNA Damage in Human Arterial Endothelial Cells
(Frontiers Media Sa, Lausanne, 2019)
Olive leaf extract (OLE) is used in traditional medicine as a food supplement and as an over-the-counter drug for a variety of its effects, including anti-inflammatory and anti-atherosclerotic ones. Mechanisms through which ...
Evaluation of DNA damage in the lymphocytes of young, elderly and Alzheimer's disease patients treated with β-estradiol in the comet assay / Evaluacija oštećenja DNK u limfocitima mladih, starih i pacijenata obolelih od Alchajmerove bolesti tretiranih β-estradiolom u komet testu
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2013)
Background: The antioxidant activity of estrogen has a beneficial impact in Alzheimer's disease. A variety of clinical studies have demonstrated that estrogen replacement therapy in postmenopausal women results in a lower ...
Evaluation of the effects of ephedrine on human lymphocytes in the comet assay / Evaluacija dejstva efedrina na limfocite čoveka u komet testu
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2011)
Ephedrine, a natural alkaloid from plants of the genus Ephedra, has a chemical structure similar to catecholamines. It is well established that catecholamines (adraneline, noradrenaline and dopamine) cause genotoxic and ...
Implications of oxidative stress in occupational exposure to lead on a cellular level
(Taylor & Francis Ltd, Abingdon, 2015)
The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and ...