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The impact of treatment choices on potential drug–drug interactions in hypertensive patients
(John Wiley and Sons Inc, 2021)
Aims: The aim of this study was to analyse potential drug–drug interactions (pDDIs) and their potential adverse drug reactions (ADRs) among hypertensive patients. Moreover, we investigated the possibility of reducing pDDIs ...
Acidity constants of cefetamet, cefotaxime and ceftriaxone; the effect of the substituent at C3 position
(Elsevier Science BV, Amsterdam, 2005)
Ionization constants of three cephalosporin antibiotics, cefetamet (CEF), cefotaxime (CFX) and ceftriaxone (CFTR) are determined using pH-potentiometric titrations at I= 0.1 M (NaCl) and t = 25 degrees C. Cefetarnet and ...
Polyphenol contents and antioxidant activity of Maydis stigma extracts
(Elsevier Sci Ltd, Oxford, 2005)
The antioxidant activity and contents of various polyphenol classes in the silks of fifteen maize hybrids with economic importance in Serbia were evaluated. Total polyphenols, tannins and proanthocyanidins were determined ...
Antimicrobial, anti-inflammatory, anti-ulcer and antioxidant activities of Carlina acanthifolia root essential oil
(Elsevier Ireland Ltd, Clare, 2007)
The root of Carlina acanthifolia All. (Asteraceae) has been traditionally used in the treatment of various disorders including stomach and skin diseases. We studied antimicrobial, anti-inflammatory, anti-ulcer and antioxidant ...
Biopharmaceutical Characterization of Ciprofloxacin HCl-Ferrous Sulfate Interaction
(Wiley-Blackwell, Malden, 2011)
The ciprofloxacin-iron interaction, resulting in a lower bioavailability, is well documented in vivo; however, a mechanistic explanation supported by experimental data of this interaction is missing. In the present study, ...
Atherogenic dyslipidemia and oxidative stress: a new look
(Elsevier Science Inc, New York, 2009)
Although results from in vitro studies and clinical trials demonstrate strong associations between oxidative stress and cardiovascular risk, to date still no convincing data are available to suggest that treatment with ...
Prediction of hepatic microsomal intrinsic clearance and human clearance values for drugs
(Elsevier Science Inc, New York, 2009)
Twenty-nine drugs of different structures were used in theoretical QSAR analysis of human hepatic microsomal intrinsic clearance (in vitro T(1/2) and in vitro CL(int)') and whole body clearance (CL(blood)). The examined ...
Preanalytical and analytical challenges in gas chromatographic determination of cholesterol synthesis and absorption markers
(Elsevier Science BV, Amsterdam, 2018)
Introduction: Cholesterol homeostasis disruption contributes to the development of different pathologies. Non cholesterol sterols (NCSs) serve as cholesterol synthesis markers (desmosterol and lathosterol), and cholesterol ...
Effect of magnesium supplementation on blood cadmium, zinc and copper levels in rabbits exposed to prolonged cadmium intoxication
(Elsevier Ireland Ltd, Clare, 2009)
Renal superoxide dismutase activity in mice exposed to acute and subacute cadmium intoxication: The role of magnesium pretreatment
(Elsevier Ireland Ltd, Clare, 2009)