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Pharmacists’ Assessment of the Difficulty and Frequency of Ethical Issues Encountered in Community Pharmacy Settings
(Springer Netherlands, 2019)
Researching ethical problems and their frequency could give us a complex picture and greater insight into the types of ethical issues that pharmacists face in providing health care. The overall aim of this study was to ...
Abnormal development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder
(Nature Publishing Group, 2015)
Subtle mood fluctuations are normal emotional experiences, whereas drastic mood swings can be a manifestation of bipolar disorder (BPD). Despite their importance for normal and pathological behavior, the mechanisms underlying ...
Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study
(Elsevier Sci Ltd, Oxford, 2019)
Background The polymorphic CYP2D6 enzyme metabolises the antipsychotic drugs risperidone and aripiprazole to their active metabolites, 9OH-risperidone and dehydroaripiprazole. The aim of this study was to quantify the ...
Phenolic profile, antibacterial, antimutagenic and antitumour evaluation of Veronica urticifolia Jacq.
(Elsevier Science BV, Amsterdam, 2014)
The phenolic profile and antibacterial, antimutagenic and antitumour activities of the methanolic extracts of Veronica urticifolia Jacq. were evaluated. HPLC-DAD/ESI-MS analysis revealed the presence of phenolic acids, ...
Nitrogen fertilization and the essential oils profile of the rhizomes of different sweet flag populations (Acorus calamus L.)
(Elsevier, 2019)
Sweet flag rhizome (Acorus calamus L., Araceae) exhibits various biological activities such as sedative, anticonvulsant,
immunosuppressant, antidiabetic, and anti-inflammatory. This plant is protected in Serbia, but due ...
Quantitative structure retention relationship modeling in liquid chromatography method for separation of candesartan cilexetil and its degradation products
(Elsevier Science BV, Amsterdam, 2015)
Artificial neural network (ANN) is a learning system based on a computation technique, which was employed for building of the quantitative structure-retention relationship (QSRR) model for candesartan cilexetil and its ...
Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures
(Springer Verlag, 2019)
Humans are exposed to multiple chemicals on a daily basis instead of to just a single chemical, yet the majority of existing toxicity data comes from single-chemical exposure. Multiple factors must be considered such as ...
A novel method for classification of wine based on organic acids
(Elsevier Sci Ltd, Oxford, 2019)
Bio-electronic tongue was linked to artificial intelligence processing unit and used for classification of wines based on carboxylic acids levels, which were indirectly related to malolactic fermentation. The system employed ...
Stability, bifurcations, and dynamics of global variables of a system of bursting neurons
(Amer Inst Physics, Melville, 2011)
An approximate mean field model of an ensemble of delayed coupled stochastic Hindmarsh-Rose bursting neurons is constructed and analyzed. Bifurcation analysis of the approximate system is performed using numerical continuation. ...
Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain
(Springer Heidelberg, Heidelberg, 2018)
Beside the key inhibition of acetylcholinesterase (AChE), involvement of oxidative stress in organophosphate (OP)-induced toxicity has been supported by experimental and human studies. On the other hand, according to our ...