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Liquid chromatographic-mass spectrometric method for the determination of fluoxetine and norfluoxetine in human plasma: Application to clinical study
(Elsevier Masson SAS, 2005)
A selective, sensitive, simple, and rapid method for the simultaneous determination of fluoxetine (FL) and norfluoxetine (nor-FL) was developed and validated, and further applied to analyze plasma samples obtained from ...
Development and validation of RP-HPLC method for cetrimonium bromide and lidocaine determination
(Elsevier Masson SAS, 2005)
The simple and rapid RP-HPLC method, for the simultaneous determination of lidocaine and cetrimonium bromide in the presence of pellet color corrigent, was developed. Separations were performed on a Beckman Ultrasphere ODS ...
Pharmacological in vitro screening of the central monoaminergic effects of Valeriana officinalis extracts
(Unija bioloških naučnih društava Jugoslavije, Beograd, 2005)
Pharmaceutical preparations of valerian root and rhizome (Valeriana officinal is L., Valerianaceae) have widespread use for sedation and treatment of hysteric states, anxiety, stress and insomnia (Morazzoni and Bombardelli ...
Changes in thymopoiesis in myasthenia gravis
(Taylor & Francis Ltd, Abingdon, 2005)
This study was undertaken to investigate T-cell maturation ill hyperplastic thymi of patients suffering from myasthenia gravis (MG). For this purpose, the expression of the major differentiational molecules (CD4, CD8, and ...
Colloidal microstructure of binary systems and model creams stabilized with an alkylpolyglucoside non-ionic emulsifier
(Springer, New York, 2005)
The aim of this study was to examine the lyotropic potential of an alkylpolyglucoside mixed emulsifier (Cetearyl glucoside&Cetearyl alcohol), which belongs to the new generation of natural (sugar) surfactants, and to ...
Gonadotropin-releasing hormone agonist administration affects the thymopoiesis in adult female rats independently on gonadal hormone production
(Blackwell Munksgaard, Copenhagen, 2005)
PROBLEM: In addition to having an indirect effect on the T-cell development by controlling the production of ovarian steroids, an accumulating body of evidence suggest that GnRH analogue (GnRH-A) administration may exert ...
A negative adaptive response is expressed in peripheral blood lymphocytes that are exposed to mitomycin C and cycloheximide
(Balkan Union of Oncology (B.U.ON.), 2005)
Purpose: Mitomycin C (MMC) and cycloheximide (CHX) are known for their apoptotic and antitumor activity. CHX is also known for its property to inhibit protein synthesis and to reduce cytotoxicity of various antitumor drugs, ...
Chronic alpha(1)-adrenoreceptor blockade produces age-dependent changes in rat thymus structure and thymocyte differentiation
(F Hernandez, Murcia, 2005)
In order to examine the influence of chronic alpha(1)-adrenergic receptor (alpha(1)-AR) blockade on the thymus structure and T-cell maturation, peripubertal and adult male rats were treated with urapidil (0.20 mg/kg BW/d; ...
Biopharmaceutical characterization of sustained release matrix tablets based on novel carbomer polymers: formulation and in vivo investigation
(Springer France, Paris, 2005)
With the increased interest in modified release dosage forms and drug delivery systems, there is an increasing concern for biopharmaceutical characterization of the formulation in the early stages of drug product development. ...
Simultaneous determination of bifonazole and benzyl alcohol in pharmaceutical formulations by reverse-phase HPLC
(Springer Heidelberg, Heidelberg, 2005)
A simple, precise and sensitive reverse-phase high performance liquid chromatographic (RP-HPLC) method has been developed for the quantitation of bifonazole, an imidazole antifungal, simultaneously with benzyl alcohol, ...