Претраживање
Приказ резултата 1-6 од 6
A Case Study of In Silico Modelling of Ciprofloxacin Hydrochloride/Metallic Compound Interactions
(Springer, New York, 2014)
With the development of physiologically based absorption models, there is an increased scientific and regulatory interest in in silico modelling and simulation of drug-drug and drug-food interactions. Clinically significant ...
An Investigation into the Influence of Process Parameters and Formulation Variables on Compaction Properties of Liquisolid Systems
(Springer, 2020)
Liquisolid technology, as a promising approach for bioavailability enhancement, has received increasing attention in recent years. However, literature reports addressing the challenges for its industrial application, ...
An Investigation into the Influence of Experimental Conditions on In Vitro Drug Release from Immediate-Release Tablets of Levothyroxine Sodium and Its Relation to Oral Bioavailability
(Springer, New York, 2011)
The aim of this study was to investigate the influence of experimental conditions on levothyroxine sodium release from two immediate-release tablet formulations which narrowly passed the standard requirements for bioequivalence ...
Artificial neural networks in the modeling and optimization of aspirin extended release tablets with Eudragit L 100 as matrix substance
(AAPS PharmSci Editorial Office, 2003)
The purpose of the present study was to model the effects of the concentration of Eudragit L 100 and compression pressure as the most important process and formulation variables on the in vitro release profile of aspirin ...
In Vitro-In Vivo Correlation for Gliclazide Immediate-Release Tablets Based on Mechanistic Absorption Simulation
(Springer, New York, 2011)
The aim of this study was to develop a drug-specific absorption model for gliclazide (GLK) using mechanistic gastrointestinal simulation technology (GIST) implemented in GastroPlus(TM) software package. A range of ...
Improvement of Aripiprazole Solubility by Complexation with (2-Hydroxy)propyl-beta-cyclodextrin Using Spray Drying Technique
(Springer, New York, 2012)
Due to the fact that the number of new poorly soluble active pharmaceutical ingredients is increasing, it is important to investigate the possibilities of improvement of their solubility in order to obtain a final ...