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Multiparticulate oral formulations as a viable strategy for precise drug dosing in pediatrics: propranolol case study / Višečestične formulacije lekova za oralnu primenu kao strategija za precizno doziranje kod pedijatrijskih pacijenata - studija slučaja propranolola
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
The development of solid dosage forms that are both convenient for administration and allow precise drug dosing for pediatric patients is one of the great challenges in contemporary pharmaceutical technology. The presented ...
Молекулско моделовање инхибитора сиртуина 2 применом молекулског докинга и анализе структуре фармакофоре / Molecular modelling of sirtuin 2 inhibitors using molecular docking and pharmacophore structure analysis
(2021)
Сиртуин 2 (SIRT2) припада фамилији NAD+-зависних хистон деацетилаза, одговорних за катализовање реакције деацетилације лизинских остатака хистона. SIRT2 регулише ћелијски циклус, утиче на опоравак оштећене ДНК и регулише ...
Improving the laboratory result release process in the light of ISO 15189:2012 standard
(Elsevier, 2021)
The ISO 15189:2012 standard section 5.9.1 requires laboratories to review results before release, considering quality control, previous results, and clinical information, if any, and to issue documented procedures about ...
Comparative efficacy evaluation of different penetration enhancement strategies for dermal delivery of poorly soluble drugs – A case with sertaconazole nitrate
(Elsevier B.V., 2021)
The aim of this study was to compare the efficacy of different approaches for enhancement of dermal availability of the highly lipophilic antifungal model drug – sertaconazole nitrate (SN). For this purpose, a physical ...
Oxidative Stress in Patients before and after On-Pump and Off-Pump Coronary Artery Bypass Grafting: Relationship with Syntax Score
(Hindawi Limited, 2021)
Objective. Coronary artery bypass grafting (CABG) represents the significant source of increased oxidative stress (OS). We aimed to follow the OS status parameters (i.e., ischemia-modified albumin (IMA), malondialdehyde ...
Supercritical fluid impregnation of microcrystalline cellulose derived from the agricultural waste with ibuprofen
(Elsevier B.V., 2021)
The present study was aimed to investigate the feasibility of loading microcrystalline cellulose derived from the agricultural waste with poorly water-soluble drug by using supercritical carbon dioxide as impregnation ...
Total leukocyte count, leukocyte subsets and their indexes in relation to cardiovascular risk in adolescent population
(Verduci Editore s.r.l, 2021)
OBJECTIVE: No studies investigated total leukocytes, their subpopulations and novel indexes based on different ratios of leukocyte subsets concerning cardiovascular risk (CV) risk in late adolescents. Therefore, the aim ...
Rheological behavior study and its significance in the assessment of application properties and physical stability of phytosome loaded hydrogels / Ispitivanje reološkog ponašanja i njegov značaj za procenu aplikativnih svojstava i fizičke stabilnosti hidrogelova sa fitosomima
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Phytosomes are amphiphilic molecular complexes of substances of plant origin and phospholipids that are considered as active ingredients of dermopharmaceutical and cosmetic formulations of potentially improved ...
Антиноцицептивно дејство кандесартана у моделу тригеминалног бола / Antinociceptive activity of candesartan in а trigeminal pain model
(2021)
Кандесартан, лек из групе антагониста ангиотензинских AT1 рецептора, користи се у терапији кардиоваскуларних болести. Међутим, извесни претклинички и клинички подаци подржавају потенцијалну примену кандесартана као аналгетика.
Chitosan/Sodium Dodecyl Sulfate Complexes for Microencapsulation of Vitamin E and Its Release Profile— Understanding the Effect of Anionic Surfactant
(MDPI, 2021)
Microencapsulation of bioactive substances is a common strategy for their protection and release rate control. The use of chitosan (Ch) is particularly promising due to its abundance, biocompatibility, and interaction with ...