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Practical issues in measuring the anticoagulant effect of direct oral anticoagulants / Praktični aspekti u određivanju antikoagulantnog dejstva direktnih oralnih antikoagulantnih lekova
(Beograd : Savez farmaceutskih udruženja Srbije, 2020)
The classical oral anticoagulants are increasingly being replaced in clinical practice by new antithrombotic drugs, which act by enabling direct inhibition of coagulation factor IIa (FIIa) or factor Xa (FXa). These drugs ...
Direct oral anticoagulants – a new chapter in anticoagulation therapy / Direktni oralni antikoagulansi - novo poglavlje u antikoagulantnoj terapiji
(Beograd : Savez farmaceutskih udruženja Srbije, 2020)
Thromboembolic events are the leading cause of morbidity and mortality worldwide. From the second half of the 20th century, vitamin K antagonists (VKAs), warfarin and acenocoumarol, were the only anticoagulants taken orally. ...