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Synthesis, characterization, and in vitro antiproliferative and antibacterial studies of tetraazamacrocyclic complexes of Co(II) and Cu(II) with pyromellitic acid
(Taylor & Francis Ltd, Abingdon, 2018)
AbstrcatNew cationic tetranuclear Co(II) and neutral binuclear Cu(II) complexes with tpmc (N,N,N,N-tetrakis-(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane) and bridging pyromellitate ligand pma (tetraanion ...
Assessing the risk of alcohol-induced dose dumping from sustained-release oral dosage forms: in vitro-in silico approach
(Taylor & Francis Ltd, Abingdon, 2018)
Consumption of alcoholic beverages with sustained-release oral dosage forms may pose a risk to patients due to potential alcohol-induced dose dumping (ADD). Regulatory guidances recommend in vitro dissolution testing to ...
In vitro/in silico approach in the development of simvastatin-loaded self-microemulsifying drug delivery systems
(Taylor & Francis Ltd, Abingdon, 2018)
Objective: The aims of this study were to formulate simvastatin (SV)-loaded self-microemulsifying drug delivery systems (SMEDDS), and explore the potential of these drug delivery systems to improve SV solubility, and also ...
Thermosensitive hydrogels for modified release of ellagic acid obtained from Alchemilla vulgaris L. extract
(Taylor & Francis As, Oslo, 2018)
Stimulus-sensitive hydrogels are used as carriers for modified release of pharmaceuticals. The synthesis of thermosensitive hydrogels poly(N-isopropylacrylamide), p(NIPAM), and poly(N-isopropylacrylamide-co-2-hydroxypropyl ...