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Dissolution assay of theophylline, diprophylline and proxyphylline from a sustained release dosage form by high performance thin layer chromatography
(Biomedical Chromatography, 1992)
The content and dissolution rate of theophylline, diprophylline and proxyphylline from a sustained release formulation were determined by UV in situ densitometry. After separation the chromatographic zones corresponding ...
The influence of β‐cyclodextrin on the solubility and dissolution rate of paracetamol solid dispersions
(Journal of Pharmacy and Pharmacology, 1992)
Abstract— The effect of cyclodextrin (β‐CD) on the solubility and dissolution rate of various paracetamol dispersion powders (1:1 w/w), and tablets was studied. Lower solubility was exhibited by a spray dried solid dispersion ...
Application of artificial neural networks in HPLC method development
(Pergamon-Elsevier Science Ltd, Oxford, 1998)
The use of artificial neural networks (ANNs) for response surface modelling in HPLC method development for amiloride and methychlothiazide separation is reported. The independent input variables were pH and methanol ...
HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms
(Pergamon-Elsevier Science Ltd, Oxford, 1998)
The objective of this investigation was to develop a HPTLC method for the determination of ceftriaxone, cefixime and cefotaxime, cephalosporins widely used in clinical practice, High performance TLC of cephalosporins was ...
Determination of fleroxacin in human serum and in dosage forms by derivative UV spectrophotometry
(Pergamon-Elsevier Science Ltd, Oxford, 1998)
Simultaneous HPTLC determination of metronidazole and its impurity 2-methyl-5-nitroimidazole in pharmaceuticals
(Springer Hungarica Kiado Kft, Budapest, 1998)
Spectrophotometric investigation of the Pd(II)-quercetin complex in 50% ethanol
(Springer-Verlag Wien, Vienna, 1998)
Composition and stability constant of the Pd(II)-quercetin complex were determined by suitable spectrophotometric methods and pH-metric measurements in 50% Ethanol. It was found that the pd(2+) ion and quercetin form a 1:1 ...
Modification of the rate of aging of diisopropylfluorophosphate-inhibited neuropathy target esterase of hen brain
(Elsevier Sci Ireland Ltd, Clare, 1998)
This study was aimed to investigate the possibility of modifying the rate of aging of diisopropylfluorophosphate-inhibited neuropathy target esterase (NTE) of hen blain. This reaction on NTE occurs with a half-time of 7.4 ...
HPTLC assay of cephalexin and cefaclor in pharmaceuticals
(John Wiley and Sons Ltd, 1998)
A simple and reliable HPTLC method for the simultaneous determination of cephalexin and cefaclor is developed and validated. The methanol-ethyl acetate-acetone-water (5:2.5:2.5:1.5 v/v/v/v) solvent system is used for the ...
Use of ANN modelling in structure-retention relationships of diuretics in RP-HPLC
(Pergamon-Elsevier Science Ltd, Oxford, 1999)
Structure-retention relationship study, conducted by RP-HPLC, was used to investigate physical chemical parameters related to the RP retention times of amiloride, hydrochlorothiazide and methyldopa in order to predict the ...