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Now showing items 161-170 of 189
A spectrophotometric method for the determination of equilibrium constants of the reversible 1,4-benzodiazepine ring-opening reaction
(Journal of the Chemical Society, Perkin Transactions 2, 1994)
A general spectrophotometric method is proposed for the quantitative investigation of the hydrolysis of 1,4-benzodiazepines which, under the effect of nucleophilic hydration, undergo reversible cleavage of the 4,5-azomethine ...
Potentiometric determination of furosemide
(Acta Pharmaceutica Jugoslavica, 1990)
A simple method is presented for the potentiometric determination of small quantities of furosemide in a pure state and in pharmaceutical formulations, using 0.1 mol l-1 chloramine-T as titrant. In potentiometric titrations ...
Application of artificial neural networks in HPLC method development
(Pergamon-Elsevier Science Ltd, Oxford, 1998)
The use of artificial neural networks (ANNs) for response surface modelling in HPLC method development for amiloride and methychlothiazide separation is reported. The independent input variables were pH and methanol ...
Application of neural networks for response surface modeling in HPLC optimization
(Elsevier Science BV, Amsterdam, 1998)
The usefulness of artificial neural networks for response surface modeling in HPLC optimization is compared with multiple regression methods. The results show that neural networks offer promising possibilities in HPLC ...
Statistical optimization applied to the HPLC determination of maprotilin
(Journal de Pharmacie de Belgique, 1998)
A reversed-phase high performance liquid chromatographic method for the determination of maprotilin in bulk drugs, ampoules and tablets is described. To achieve maximum quantity, optimum conditions were used. In order to ...
Potentiometric titration of pralidoxime chloride (2-pyridinealdoxime methochloride) with a silver indicator electrode
(Maik Nauka/Interperiodica, New York, 1998)
It is shown that a silver indicator electrode can be used in the potentiometric titration of pralidoxime chloride [2-pyridinealdoxime methochloride (PAM-2)] with palladium(II) chloride and silver nitrate solutions. The ...
Spectrophotometric determination of fleroxacin in tablets
(Journal de Pharmacie de Belgique, 1998)
Fleroxacin belongs to the third genegation of multiple fluorinated antibacterial quinolone derivatives widely used in the treatment of urinary infections. In aqueous medium fleroxacin undergoes to complex acid-base equilibrium ...