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The large plasmidome of Lactococcus lactis subsp. lactis bv. diacetylactis S50 confers its biotechnological properties
(Elsevier B.V., 2021)
Plasmids are autonomous episomally replicating genetic elements, which carry backbone genes important for the replication and maintenance within their host, and accessory genes that might confer an advantage to their host ...
Preparation of floating polymer-valsartan delivery systems using supercritical CO2
(Springer Science and Business Media B.V., 2021)
This study investigates pharmaceutical polymers (Soluplus®, HPMCAS, and Eudragit® E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa ...
The role of toxic metals and metalloids in nrf2 signaling
(MDPI AG, 2021)
Nuclear factor erythroid 2-related factor 2 (Nrf2), an emerging regulator of cellular resis-tance to oxidants, serves as one of the key defensive factors against a range of pathological processessuch as oxidative damage, ...
Colloidal nanodispersions for the topical delivery of Ibuprofen: Structure, dynamics and bioperformances
(Elsevier B.V., 2021)
Colloidal liquid-in-liquid nanodispersions such as micro- and nanoemulsions were developed, characterized and compared as potential carriers for the topical administration of ibuprofen. Both colloidal systems were based ...
Anthropogenic influence on seasonal and spatial variation in bioelements and non-essential elements in honeybees and their hemolymph
(Elsevier Inc., 2021)
Honeybee colony losses have been a focus of research in the last years, due to the importance of managed honeybee colonies for economy and ecology. Different unfavorable conditions from the outside environment have a strong ...
Effect of ibuprofen entrapment procedure on physicochemical and controlled drug release performances of chitosan/xanthan gum polyelectrolyte complexes
(Elsevier B.V., 2021)
The effect of the entrapment procedure of a poorly water soluble drug (ibuprofen) on physicochemical and drug release performances of chitosan/xanthan polyelectrolyte complexes (PECs) was investigated to achieve controlled ...
Photocontrollable PROTAC molecules – structure and mechanism of action / Fotokontrolisani PROTAC molekuli - struktura i mehanizam dejstva
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Traditional drug discovery strategies are usually focused on occupancy of binding sites that directly affect functions of proteins. Hence, proteins that lack such binding sites are generally considered pharmacologically ...
Corona Charged Aerosol Detector in studying retention and β-cyclodextrin complex stability using RP-HPLC
(Elsevier B.V., 2021)
Binding between cyclodextrin (CD) cavity and guest molecule in Reversed Phase High-Performance Liquid Chromatography (RP-HPLC) is dynamic process. In general, increasing CD concentration is inducing inclusion complex ...
Rheological behavior study and its significance in the assessment of application properties and physical stability of phytosome loaded hydrogels / Ispitivanje reološkog ponašanja i njegov značaj za procenu aplikativnih svojstava i fizičke stabilnosti hidrogelova sa fitosomima
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Phytosomes are amphiphilic molecular complexes of substances of plant origin and phospholipids that are considered as active ingredients of dermopharmaceutical and cosmetic formulations of potentially improved ...
Predicting drug release from diazepam FDM printed tablets using deep learning approach: Influence of process parameters and tablet surface/volume ratio
(Elsevier B.V., 2021)
The aim of this study was to apply artificial neural networks as deep learning tools in establishing a model for understanding and prediction of diazepam release from fused deposition modeling (FDM) printed tablets. Diazepam ...