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The Role of Paracellular Transport in the Intestinal Absorption and Biopharmaceutical Characterization of Minoxidil
(MDPI, 2022)
The purpose of this study was to evaluate mechanisms behind the intestinal permeability of minoxidil, with special emphasis on paracellular transport, and elucidate the suitability of minoxidil to be a reference drug for ...
Person-Centred Care Interventions in Pharmaceutical Care
(Springer Science and Business Media Deutschland GmbH, 2022)
This chapter is divided into four sections. The first section introduces the concept of person-centred care within pharmaceutical care delivery and provides a historical context. The second section focuses on the professionals ...
β-Adrenoceptor Blockade Moderates Neuroinflammation in Male and Female EAE Rats and Abrogates Sexual Dimorphisms in the Major Neuroinflammatory Pathways by Being More Efficient in Males
(Springer, 2022)
Our previous studies showed more severe experimental autoimmune encephalomyelitis (EAE) in male compared with female adult rats, and moderating effect of propranolol-induced β-adrenoceptor blockade on EAE in females, the ...
Copolymerization of aniline and gallic acid: Novel electroactive materials with antioxidant and antimicrobial activities
(Elsevier Ltd, 2022)
Novel electroactive PANI-GA micro/nanostructured functional copolymers/co-oligomers were synthesized by the oxidative copolymerization of aniline and gallic acid (GA) in an aqueous solution, using ammonium peroxydisulfate ...
Albuminuria as a risk factor for mild cognitive impairment and dementia-what is the evidence?
(Oxford University Press, 2022)
Kidney dysfunction can profoundly influence many organ systems, and recent evidence suggests a potential role for increased albuminuria in the development of mild cognitive impairment (MCI) or dementia. Epidemiological ...
Brain dysfunction in tubular and tubulointerstitial kidney diseases
(Oxford University Press, 2022)
Kidney function has two important elements: glomerular filtration and tubular function (secretion and reabsorption). A persistent decrease in glomerular filtration rate (GFR), with or without proteinuria, is diagnostic of ...
Application of nanofat for treatment of traumatic faecal incontinence after sphincteroplasty – A pilot study
(John Wiley and Sons Inc, 2022)
Aim: The aim of this study was to investigate whether the application of nanofat contain-ing stem cells improves continence in women who had previously undergone anal sphinc-teroplasty with unsatisfactory long-term ...
An approach for determining allowable between reagent lot variation
(De Gruyter Open Ltd, 2022)
Clinicians trust medical laboratories to provide reliable results on which they rely for clinical decisions. Lab- oratories fulfil their responsibility for accurate and consistent results by utilizing an arsenal of approaches, ...
Moving average procedures as an additional tool for real-time analytical quality control: challenges and opportunities of implementation in small-volume medical laboratories
(Croatian Society of Medical Biochemistry and Laboratory Medicine, 2022)
Introduction: Moving average (MA) is one possible way to use patient results for analytical quality control in medical laboratories. The aims of this study were to: (1) implement previously optimized MA procedures for 10 ...
Long-term stability of clopidogrel solid dispersions-Importance of in vitro dissolution test
(NLM (Medline), 2022)
Formulation of solid dispersions (SDs), in which the drug substance is dissolved or dispersed inside a polymer matrix, is one of the modern approaches to increase the solubility and dissolution rate of poorly soluble active ...