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Critical review on the analytical methods for the determination of zwitterionic antiepileptic drugs-Vigabatrin, Pregabalin, and Gabapentin - In bulk and formulations
(Taylor & Francis Inc, Philadelphia, 2014)
Drugs with antiepileptic activity constitute a group of heterogeneous compounds and therefore their determination cannot follow a universal procedure. Among them, vigabatrin, pregabalin, and gabapentin are of similar nature, ...
Phase behaviour, microstructure and ibuprofen solubilization capacity of pseudo-ternary nonionic microemulsions
(Elsevier Science BV, Amsterdam, 2011)
This study investigated phase behaviour, microstructure and solubilization capacity of pseudo-ternary surfactant/cosurfactant/isopropyl myristate/water systems employing complex mixtures of nonionic surfactants for formation ...
Fluoroquinolone-resistant Achromobacter xylosoxidans clinical isolates from Serbia: high prevalence of the aac-(6)-Ib-cr gene among resistant isolates
(Springer, Dordrecht, 2019)
The aim of this study was to evaluate the contribution of plasmid-mediated genes and efflux to fluoroquinolone resistance in collection of Achromobacter spp. gathered during a 3-year period. Susceptibility to ciprofloxacin ...
Alpha-1-antitrypsin Phenotypes and Neutrophil Elastase Gene Promoter Polymorphisms in Lung Cancer
(Springer, Dordrecht, 2011)
Imbalance between neutrophil elastase and alpha-1-antitrypsin (AAT) leads to emphysema in smokers as well as in patients with inherited alpha-1-antitrypsin deficiency. AAT as a proven inhibitor of apoptosis may play role ...
A health-related quality of life and pharmacotherapy costs study for patients with cystic fybrosis, gaucher disease and chronic myeloid leukemia in Bulgaria
(Diagnosis Press Ltd, Sofia, 2013)
The aim of the present study was to analyze the cost of pharmacotherapy and quality of life of patients with cystic fibrosis (CF), Gaucher disease (GD) and chronic myeloid leukemia (CML) in Bulgaria. Data for the pharmacotherapy ...
Establishing Design Space for Tramadol HCl Release from Hydrophilic Matrix Tablets
(Colegio Farmaceuticos Provincia De Buenos Aires, La Plata, 2014)
The aim of this study was establishing design space for robust formulation of hydrophilic extended release matrix tablets with tramadol hydrochloride as highly soluble, high dose drug. In the first part of the study, linear ...
Water-Dilutable Biocompatible Microemulsion Systems: Design and Characterisation
(Carl Hanser Verlag, Munich, 2013)
The present study describes a screening approach in design of microemulsion preconcentrates (self-microemulsifying systems) comprising: PEG-8 caprylic/capric glycerides (Labrasol (R)) (surfactant), PEG-40 hydrogenated ...
Cationic surfactants-modified natural zeolites: improvement of the excipients functionality
(Informa Healthcare, London, 2010)
Context: In this study an investigation of cationic surfactants-modified natural zeolites as drug formulation excipient was performed. Objective: The aim of this work was to carry out a study of the purified natural zeolitic ...
Factorial Design in Optimization of Chromatographic Separation of Ramipril and Its Impurities
(Springer Heidelberg, Heidelberg, 2010)
In this paper optimization of chromatographic retention of ramipril and its five impurities employing factorial design is presented. On the basis of preliminary experiments three factors were chosen as inputs (acetonitrile ...
Antioxidant activity of Filipendula hexapetala flowers
(Elsevier Science BV, Amsterdam, 2007)
The antioxidant activity of the methanol extract of Filipendula hexapetala flowers was assessed by the assay for ferric-reducing antioxidant power (FRAP), the assay for DPPH free radical scavenging ability (DPPH) and the ...