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Evaluation of chitosan/xanthan gum polyelectrolyte complexes potential for pH-dependent oral delivery of escin
(Elsevier B.V., 2022)
Escin is an amphiphilic and weakly acidic drug that oral administration may lead to the irritation of gastric mucosa. The entrapment of escin into chitosan (CH)/xanthan gum (XG)-based polyelectrolyte complexes (PECs) can ...
Two component model of microtubules – subsonic and supersonic solitary waves
(Elsevier, 2022)
This work represents a contribution to modelling nonlinear dynamics of microtubules, the basic components of the eukaryotic cytoskeleton. Their dynamics can be explained in terms of kink and antikink solitary waves. Special ...
Closing the Loop: Dyeing and Adsorption Potential of Mulberry Wood Waste
(Taylor & Francis, 2022)
ABSTRACT
This study reports the successful transformation of mulberry wood waste
into natural textile dye and adsorbent for Pb2+ ions from an aqueous solution. Fabrics of different chemical compositions were dyed using ...
Involvement of environmentally relevant toxic metal mixture in Alzheimer's disease pathway alteration and protective role of berberine: Bioinformatics analysis and toxicogenomic screening
(Elsevier Ltd, 2022)
We aimed to examine the molecular basis of the positive effect of berberine against environmentally relevant toxic metal-linked Alzheimer’s disease (AD). The Comparative Toxicogenomic Database (CTD) retrieved a set of genes ...
Probiotic reduced the impact of phthalates and bisphenol A mixture on type 2 diabetes mellitus development: Merging bioinformatics with in vivo analysis
(Elsevier, 2021)
Linkage between bis(2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP), and bisphenol A (BPA) coexposure and type 2 diabetes mellitus (T2DM), as well as ability of multi-strained probiotic to reduce DEHP, DBP and BPA ...
Characterizing HIV-Preventive, Plasma Tenofovir Concentrations-A Pooled Participant-level Data Analysis From Human Immunodeficiency Virus Preexposure Prophylaxis (PrEP) Clinical Trials
(Oxford University Press, 2022)
Background. Daily dosing of tenofovir disoproxil fumarate, with or without emtricitabine, has high efficacy in preventing human immunodeficiency virus (HIV) infection when individuals are adherent. The target protective ...
Fluoride subacute testicular toxicity in Wistar rats: Benchmark dose analysis for the redox parameters, essential elements and DNA damage
(Elsevier Ltd, 2022)
Excessive fluoride (F−) levels in the environment could induce different pathological changes, including comorbidities in reproductive functions. Hence, the aim of the present in vivo study was to explore F− subacute ...
Assessment of the combined effects of chromium and benzene on the rat neuroendocrine and immune systems
(Academic Press Inc., 2021)
This study assessed the hypothalamic-pituitary-adrenocortical (HPA) axis and lymphoid organs (thymus, spleen, and bone marrow) of Wistar rats treated with a mixture of chromium and benzene. Animals were assessed at three ...
Multi-strain probiotic ameliorated toxic effects of phthalates and bisphenol A mixture in Wistar rats
(Elsevier Ltd, 2020)
Phthalates and bisphenol A, to which people are mainly exposed through food, interfere with the body's endocrine system, along with various other toxic effects. Literature data suggest that probiotic cultures might be able ...
Sirtuins as molecular targets, mediators, and protective agents in metal‑induced toxicity
(Springer, 2021)
Metal dyshomeostasis, and especially overexposure, is known to cause adverse health effects due to modulation of a variety of metabolic pathways. An increasing body of literature has demonstrated that metal exposure may ...