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In silico evaluation of angiotensin II receptor antagonist's plasma protein binding using computed molecular descriptors / In silico procena vezivanja za proteine plazme antagonista receptora angiotenzina II primenom izračunatih molekulskih deskriptora
(Univerzitet u Nišu - Medicinski fakultet, Niš, 2014)
The discovery of new pharmacologically active substances and drugs modeling led to necessity of predicting drugs properties and its ADME data. Angiotensin II receptor antagonists are a group of pharmaceuticals which modulate ...
Evaluation of pharmacists' knowledge and attitudes regarding rare diseases and orphan drugs / Procena znanja i stavova farmaceuta o retkim bolestima i lekovima za retke bolesti
(Univerzitet u Nišu - Medicinski fakultet, Niš, 2013)
Rare diseases (RD) are very heterogenic group of disorders affecting less than 5 out of 10.000 people in the European Union (EU), at the same time putting them in danger or disabling them chronically. It is estimated that ...
New oral anticoagulant drugs in atrial fibrillation and acute coronary syndrome / Novi oralni antikoagulantni lekovi kod atrijalne fibrilacije i akutnog koronarnog sindroma
(Univerzitet u Nišu - Medicinski fakultet, Niš, 2013)
After an acute coronary syndrome, patients remain at risk of recurrent ischemic events despite the use of antiplatelet therapy. In order to reduce the risk of recurrent ischemia in the treatment of patients with acute ...
Correlation between angiotensin-converting enzyme inhibitors lipophilicity and protein binding data / Zavisnost lipofilnosti i vezivanja za proteine plazme inhibitora angiotenzin konvertujućeg enzima
(Univerzitet u Nišu - Medicinski fakultet, Niš, 2012)
Angiotensin-converting enzyme (ACE) inhibitors represent a significant group of drugs primarily used in the treatment of hypertension and congestive heart failure. In this research, seven ACE inhibitors (enalapril, quinapril, ...