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Assessment of hot-melt coating methods for multiparticulate substrates: mortar-coating vs. pan-coating / Procena metoda za oblaganje višečestičnih supstrata topljenjem - oblaganje u pateni vs. oblaganje u bubnju
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Hot-melt coating (HMC) is an alternative, solvent-free coating method generally used to modify substrate release rate and/or mask its unpleasant taste. The aim of this study was to assess two HMC methods (pan-coating and ...
Safety and efficacy of interleukin inhibitors in elderly patients with rheumatoid arthritis, psoriasis, and psoriatic arthritis / Bezbednost i efikasnost inhibitora interleukina u terapiji reumatoidnog artritisa, psorijaze i psorijaznog artritisa u populaciji starih osoba
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Elderly patients with rheumatoid arthritis, psoriasis and psoriatic arthritis encompass those with elderly-onset disease, over 60 years of age, but also those with earlier disease onset who entered old age. Considering the ...
Spectrophotometric determination of morin in strawberries and their antioxidant activity / Spektrofotometrijsko određivanje sadržaja morina u jagodama i njihove antioksidantne aktivnosti
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Morin is one of the flavonoids with intensive antioxidant activity. With the aim to use its benefits on human health, there is an increasing trend to pay attention to its content in food or supplements. The simplicity ...
Medicinal chemistry of histone deacetylase inhibitors / Medicinska hemija inhibitora histon deacetilaza
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Today, we are witnessing an explosion of scientific concepts in cancer chemotherapy. It has been considered for a long time that genetic instability in cancer should be treated with drugs that directly damage the DNA. ...
Food additives – risk analysis and legislation / Prehrambeni aditivi – analiza rizika i regulativa
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Food additive is any substance not normally consumed as a food, the intentional addition of which to food for a technological purpose results in it or its by-products becoming a component of such foods. The use of each new ...
Photocontrollable PROTAC molecules – structure and mechanism of action / Fotokontrolisani PROTAC molekuli - struktura i mehanizam dejstva
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Traditional drug discovery strategies are usually focused on occupancy of binding sites that directly affect functions of proteins. Hence, proteins that lack such binding sites are generally considered pharmacologically ...
A review of botanical characteristics, chemical composition, pharmacological activity and use of parsley / Pregled botaničkih karakteristika, hemijskog sastava, farmakološke aktivnosti i primene peršuna
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Parsley is a biennial aromatic plant from the Apiaceae family, which is characterized by an unbranched root, pinnately divided leaves, umbels and schizocarp. It contains essential oil in all parts, with phenylpropane and ...
Direct oral anticoagulants – a new chapter in anticoagulation therapy / Direktni oralni antikoagulansi - novo poglavlje u antikoagulantnoj terapiji
(Beograd : Savez farmaceutskih udruženja Srbije, 2020)
Thromboembolic events are the leading cause of morbidity and mortality worldwide. From the second half of the 20th century, vitamin K antagonists (VKAs), warfarin and acenocoumarol, were the only anticoagulants taken orally. ...
Experimental design in HPLC separation of pharmaceuticals / Primena eksperimentalnog dizajna za razdvajanje lekova HPLC metodom
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Design of Experiments (DoE) is an indispensable tool in contemporary drug analysis as it
simultaneously balances a number of chromatographic parameters to ensure optimal separation
in High Pressure Liquid Chromatography ...
Chemometric window to antimicrobial activity of biomolecules isolated from endophytic fungi / Hemometrijski prozor ka antibakterijskoj aktivnosti biomolekula izolovanih iz endofitnih gljiva
(Pharmaceutical Association of Serbia, 2020)
Drug resistance, especially bacterial antibiotic resistance, is recognized as a global phenomenon. Potential of endophytic fungi as producers of secondary metabolites with wide spectra of different bioactivities in the ...