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Specifičnosti farmakokinetike kod starijih pacijenata
(Savez farmaceutskih udruženja Srbije, Beograd, 2009)
Aging represents a very complex biological process that implies specific changes in body composition and physiological functions. Aging can affect drug absorption, distribution, metabolism, and excretion leading to significant ...
Pharmacist in health-care team involved in treatment of depression and anxiety / Farmaceut u zdravstvenom timu za terapiju depresija i anksioznosti
(Savez farmaceutskih udruženja Srbije, Beograd, 2007)
The complexities of actions, pharmacokinetic characteristics, potential for interactions of antidepressants and anxiolitics require wide range of issues to consider in the provision of pharmaceutical care. Pharmacists have ...
Rational pharmacotherapy of cardiovascular diseases: The importance of pharmacokinetics, interactions and side effects / Racionalna farmakoterapija kardiovaskularnih bolesti - značaj farmakokinetike, interakcija i neželjenih efekata lekova
(Savez farmaceutskih udruženja Srbije, Beograd, 2003)
Cardiovascular diseases therapy is very complex task, primarily due to the fact that many of these diseases are simultaneous, that one class of drugs is used in several indications, and that the therapy is often of combined ...
Pharmacokinetic aspects in dosing regimen in paediatrics / Farmakokinetički aspekti doziranja lekova u pedijatriji
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Clinical trials in paediatric patients are limited due to certain practical, ethical and regulatory aspects. Accordingly, after performing pharmacokinetic (PK) and efficacy/safety clinical trials in adults, clinical trials ...
Concept and utility of population pharmacokinetic and pharmacokinetic/ pharmacodynamic models in drug development and clinical practice / Koncept i upotreba populacionih farmakokinetičkih i farmakokinetičko/farmakodinamičkih modela u razvoju leka i kliničkoj praksi
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Due to frequent clinical trial failures and consequently fewer new drug approvals, the need
for improvement in drug development has, to a certain extent, been met using model-based drug
development. Pharmacometrics is a ...
Clinical pharmacokinetics of inhailed corticosteroids / Klinička farmakokinetika inhalacionih kortikosteroida
(Savez farmaceutskih udruženja Srbije, Beograd, 2011)
Corticosteroids, as anti-inflammatory drugs, represent the cornerstone of asthma treatment. Inhalation route provides rapid local effect with simultaneous elimination or minimization of systemic side effects that are ...
Pharmacokinetics of inhaled corticosteroids / Farmakokinetika inhalacionih kortikosteroida
(Savez farmaceutskih udruženja Srbije, Beograd, 2002)
The inhaled corticosteroids have improved asthma therapy significantly. The inhaled route allows the delivery of relatively small doses directly to the airway, providing a high local concentration and minimizing systemic ...
Obesity as a factor of pharmacokinetic variability / Gojaznost kao faktor farmakokinetičke varijabilnosti
(Savez farmaceutskih udruženja Srbije, Beograd, 2011)
Increased prevalence of obesity of the population in the recent years suggests that health professionals will be, in the near future, in a position to provide daily health care services to the obese patients. This population ...
The influence of smoking on the urine paracetamol elimination / Eliminacija paracetamola urinom kod pušača
(Savez farmaceutskih udruženja Srbije, Beograd, 2004)
The aim of this study was to evaluate the influence of smoking on the urine paracetamol elimination. Fourteen healthy female volunteers took part in this controlled study. Seven (23+/-3 years; 50 +/- 2 kg; x+/-SD) were ...
Clinically important interactions of antibiotics and antifungal drugs with other drugs / Klinički značajne interakcije antibiotika i antimikotika sa drugim lekovima
(Savez farmaceutskih udruženja Srbije, Beograd, 2007)
Antibiotics (AB) and antifungals are large, heterogeneous, and commonly prescribed groups of drugs. Even thou, their use in therapy are considered to be safe, during concomitant use with other drugs the result can be ...