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Приказ резултата 61-70 од 78
A preliminary study of beta-cyclodextrin/metoprolol tartrate inclusion complex for potential enantiomeric separation
(Pergamon-Elsevier Science Ltd, Oxford, 2001)
The inclusion complex formation between Metoprolol tartarata (MeT) and beta -cyclodextrin (beta -CD) has been investigated using hyperchromic shift at lambda (max) 274.4 nm of MeT. Different parameters such as stirring ...
Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis
(Pergamon-Elsevier Science Ltd, Oxford, 2001)
A method has been developed for separation of nitrendipine and its impurities of reaction partners and side reaction products by high-performance liquid chromatographic method on a RP-ls column and detection at 238 nm. The ...
Analytical method development supported by DoE-DS approach for enantioseparation of (S,S)- and (R,R)-moxifloxacin
(Elsevier B.V., 2023)
In this paper, method for enantiomeric purity testing of fourth-generation fluoroquinolone, moxifloxacin hydrochloride, was developed and validated. Exceptional enantioselectivity for this assay was achieved using cyclodextrin ...
Predicting liquid chromatography−electrospray ionization/mass spectrometry signal from the structure of model compounds and experimental factors; case study of aripiprazole and its impurities
(Elsevier Inc., 2023)
A priori estimation of analyte response is crucial for the efficient development of liquid chromatography–electrospray ionization/mass spectrometry (LC–ESI/MS) methods, but remains a demanding task given the lack of knowledge ...
Coulometric determination of sulphisomidine, sulphamethoxydiazine and sulphamoxole
(Journal of Pharmaceutical and Biomedical Analysis, 1991)
Determination of anti-secalin antibodies in sera from coeliac patients by ELISA-based assay
(Elsevier, 1998)
Coeliac disease (CD) is a permanent intolerance
to dietary prolamins (alcohol soluble protein fraction of cereal gluten) from selected cereals (wheat,
rye, barley and oats) resulting in small intestinal
villus atrophy ...
Generic approach in a gradient elution HPLC method development that enables troubleshooting free method transfer
(Elsevier B.V., 2022)
Nowadays, method development is strongly focused on reducing time needed for method development and execution. This subject specially concerns gradient elution methods regarding the usual need for trouble shooting assistance ...
Chiral ligand-exchange chromatography for diastereo-enantio separation of exametazime
(Pergamon-Elsevier Science Ltd, Oxford, 2003)
The diastereo-enantio separation of isomeric mixtures of exametazime (HM-PAO) by liquid chromatography is described using an achiral sorbent (RP-18). A chiral eluent with the initial complex of Cu(II) and the optically ...
Corona Charged Aerosol Detector in studying retention and β-cyclodextrin complex stability using RP-HPLC
(Elsevier B.V., 2021)
Binding between cyclodextrin (CD) cavity and guest molecule in Reversed Phase High-Performance Liquid Chromatography (RP-HPLC) is dynamic process. In general, increasing CD concentration is inducing inclusion complex ...
High-performance liquid chromatographic method for the determination of moclobemide and its two major metabolites in human plasma
(Elsevier Science BV, Amsterdam, 2007)
A selective, sensitive, and simple high-performance liquid chromatographic (HPLC) method was developed for the determination of moclobemide and its two major metabolites, Ro 12-5637 and Ro 12-8095, in human plasma. Sample ...