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Grape Seed Oil Characterization: A Novel Approach for Oil Quality Assessment
(Wiley-VCH Verlag, 2020)
The amount of organic pomace, left behind agricultural processes, is continuously rising in accordance with industrial progress. Grape pomace, generated in the wine industry all over the world, represents a raw material ...
Pharmacists’ clinical knowledge and practice in the safe use of contraceptives: real knowledge vs. self-perception and the implications
(BioMed Central Ltd, 2021)
Background: Pharmacists are often the first healthcare professionals that patients contact with their illnesses and requests for medical information, which is enhanced following the recent COVID-19 pandemic. Community ...
Heavy metal and pesticide exposure: A mixture of potential toxicity and carcinogenicity
(Elsevier B.V., 2020)
There is a growing body of evidence that various pesticides and heavy metals are carcinogenic. If not directly, there is also evidence that shows that these compounds can participate in carcinogenesis in a passive or ...
Sex-Based Differences in Monocytic Lineage Cells Contribute to More Severe Collagen-Induced Arthritis in Female Rats Compared with Male Rats
(Springer Nature, 2020)
Monocytes’ plasticity has an important role in the development of rheumatoid arthritis (RA), an autoimmune disease exhibiting greater prevalence in women. Contribution of this phenomenon to sex bias in RA severity was ...
Synthesis, in silico, and in vitro studies of novel dopamine D2 and D3 receptor ligands
(Wiley-VCH Verlag, 2021)
Dopamine is an important neurotransmitter in the human brain and its altered concentrations can lead to various neurological diseases. We studied the binding of novel compounds at the dopamine D2 (D2R) and D3 (D3R) receptor ...
Oxidative Stress in Patients before and after On-Pump and Off-Pump Coronary Artery Bypass Grafting: Relationship with Syntax Score
(Hindawi Limited, 2021)
Objective. Coronary artery bypass grafting (CABG) represents the significant source of increased oxidative stress (OS). We aimed to follow the OS status parameters (i.e., ischemia-modified albumin (IMA), malondialdehyde ...
Supercritical fluid impregnation of microcrystalline cellulose derived from the agricultural waste with ibuprofen
(Elsevier B.V., 2021)
The present study was aimed to investigate the feasibility of loading microcrystalline cellulose derived from the agricultural waste with poorly water-soluble drug by using supercritical carbon dioxide as impregnation ...
Total leukocyte count, leukocyte subsets and their indexes in relation to cardiovascular risk in adolescent population
(Verduci Editore s.r.l, 2021)
OBJECTIVE: No studies investigated total leukocytes, their subpopulations and novel indexes based on different ratios of leukocyte subsets concerning cardiovascular risk (CV) risk in late adolescents. Therefore, the aim ...
Bcs class iv oral drugs and absorption windows: Regional-dependent intestinal permeability of furosemide
(MDPI AG, 2020)
Biopharmaceutical classification system (BCS) class IV drugs (low-solubility low-permeability) are generally poor drug candidates, yet, ~5% of oral drugs on the market belong to this class. While solubility is often ...
H2FPEF score predicts atherosclerosis presence in patients with systemic connective tissue disease
(Wiley Periodicals, 2021)
Background: Cardiovascular diseases are common cause of morbidity and mortality in patients with systemic connective tissue diseases (SCTD) due to accelerated atherosclerosis which couldn't be explained by traditional risk ...