Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction
Abstract
Obesity is defined as an excess body fat that impairs health and is associated with increased risk of heart failure (HF), particularly HF with preserved ejection fraction (HFpEF), evolving into a 'HFpEF obesity phenotype'. The interplay between obesity and cardiorespiratory fitness, primary clinical parameters in HF, requires further exploration. The contribution of body composition compartments in the development and progress of HF has been the object of numerous studies. Here we focus on how fat mass and lean tissues affect cardiorespiratory fitness, with emphasis on their effects on peak oxygen consumption. Moreover, while several studies have focused on characterization of body composition compartments, here we describe also recent findings related to abnormal and/or dysfunctional lean mass, especially in HFpEF.
Keywords:
body composition / cardiorespiratory fitness / fat mass / heart failure with preserved ejection fraction / lean mass / skeletal muscle massSource:
Future Cardiology, 2017, 13, 5, 451-463Publisher:
- Future Medicine Ltd, London
Funding / projects:
- Mentored Clinical & Population Research Award from the American Heart Association - 16MCPRP31100003
DOI: 10.2217/fca-2017-0023
ISSN: 1479-6678
WoS: 000418475500007
Scopus: 2-s2.0-85029663418
Collections
Institution/Community
PharmacyTY - JOUR AU - Carbone, Salvatore AU - Popović, Dejana AU - Lavie, Carl J. AU - Arena, Ross PY - 2017 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/2854 AB - Obesity is defined as an excess body fat that impairs health and is associated with increased risk of heart failure (HF), particularly HF with preserved ejection fraction (HFpEF), evolving into a 'HFpEF obesity phenotype'. The interplay between obesity and cardiorespiratory fitness, primary clinical parameters in HF, requires further exploration. The contribution of body composition compartments in the development and progress of HF has been the object of numerous studies. Here we focus on how fat mass and lean tissues affect cardiorespiratory fitness, with emphasis on their effects on peak oxygen consumption. Moreover, while several studies have focused on characterization of body composition compartments, here we describe also recent findings related to abnormal and/or dysfunctional lean mass, especially in HFpEF. PB - Future Medicine Ltd, London T2 - Future Cardiology T1 - Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction VL - 13 IS - 5 SP - 451 EP - 463 DO - 10.2217/fca-2017-0023 ER -
@article{ author = "Carbone, Salvatore and Popović, Dejana and Lavie, Carl J. and Arena, Ross", year = "2017", abstract = "Obesity is defined as an excess body fat that impairs health and is associated with increased risk of heart failure (HF), particularly HF with preserved ejection fraction (HFpEF), evolving into a 'HFpEF obesity phenotype'. The interplay between obesity and cardiorespiratory fitness, primary clinical parameters in HF, requires further exploration. The contribution of body composition compartments in the development and progress of HF has been the object of numerous studies. Here we focus on how fat mass and lean tissues affect cardiorespiratory fitness, with emphasis on their effects on peak oxygen consumption. Moreover, while several studies have focused on characterization of body composition compartments, here we describe also recent findings related to abnormal and/or dysfunctional lean mass, especially in HFpEF.", publisher = "Future Medicine Ltd, London", journal = "Future Cardiology", title = "Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction", volume = "13", number = "5", pages = "451-463", doi = "10.2217/fca-2017-0023" }
Carbone, S., Popović, D., Lavie, C. J.,& Arena, R.. (2017). Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction. in Future Cardiology Future Medicine Ltd, London., 13(5), 451-463. https://doi.org/10.2217/fca-2017-0023
Carbone S, Popović D, Lavie CJ, Arena R. Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction. in Future Cardiology. 2017;13(5):451-463. doi:10.2217/fca-2017-0023 .
Carbone, Salvatore, Popović, Dejana, Lavie, Carl J., Arena, Ross, "Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction" in Future Cardiology, 13, no. 5 (2017):451-463, https://doi.org/10.2217/fca-2017-0023 . .