TY  - JOUR
AU  - Janošević-Ležaić, Aleksandra
AU  - Bajuk-Bogdanović, Danica
AU  - Ćirić-Marjanović, Gordana
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5612
AB  - In situ Raman spectroscopy was used for the first time to study the reaction intermediates/products of the
oxidative polymerization of aniline to polyaniline (PANI) with peroxydisulfate in aqueous solutions of different
initial acidity. Raman spectra were recorded for the drops of reaction mixture taken at various reaction times.
Five reaction systems with different pH of the monomer solution (pHmon), leading to 1-D nanostructured PANIs
(pHmon =5.8, 4.6 and 4.5) and granular PANIs (pHmon= 3.4 and 1.0) were explored. Spectral characteristics of
different reaction phases - athermal, exothermic and post-propagation were identified and correlated with the
proposed mechanisms of aniline polymerization and nanostructures formation. For the nanostructured PANIs,
the athermal phase was characterized by pronounced strengthening of the δ(N H)/ν(C––N)Q band at
1510–1520 cm 1, while the characteristic of the second exothermic phase was the strengthening of the ν(C~C)B/
ν(C~C)Phz band at c.a. 1636 cm 1 which becomes stronger than the ν(C––C)Q/ν(C~C)SQ band at c.a. 1590 cm–1.
For granular PANIs, the band at 1590 cm–1 was stronger than that at 1630 cm–1 for all reaction phases. For all
reaction systems, characteristic feature of the post-propagation phase was strengthening of the ν(C~N+•) band at
1330–1340 cm 1 due to delocalized polarons. For granular PANIs, the band associated with phenazine-like units
at c.a. 1415 cm 1 disappeared after the exothermic phase, while for nanostructured PANIs it was seen until the
end of the reaction. The obtained results are expected to be useful in further investigations of the intermediates/
products and mechanisms of polymerizations of other aromatic amines.
PB  - Elsevier
T2  - Synthetic Metals  Synthetic Metals
T1  - In situ Raman spectroscopy study of the oxidative polymerization of aniline in media of different acidity
VL  - 305
SP  - 117602
DO  - 10.1016/j.synthmet.2024.117602
ER  - 

@article{
author = "Janošević-Ležaić, Aleksandra and Bajuk-Bogdanović, Danica and Ćirić-Marjanović, Gordana",
year = "2024",
abstract = "In situ Raman spectroscopy was used for the first time to study the reaction intermediates/products of the
oxidative polymerization of aniline to polyaniline (PANI) with peroxydisulfate in aqueous solutions of different
initial acidity. Raman spectra were recorded for the drops of reaction mixture taken at various reaction times.
Five reaction systems with different pH of the monomer solution (pHmon), leading to 1-D nanostructured PANIs
(pHmon =5.8, 4.6 and 4.5) and granular PANIs (pHmon= 3.4 and 1.0) were explored. Spectral characteristics of
different reaction phases - athermal, exothermic and post-propagation were identified and correlated with the
proposed mechanisms of aniline polymerization and nanostructures formation. For the nanostructured PANIs,
the athermal phase was characterized by pronounced strengthening of the δ(N H)/ν(C––N)Q band at
1510–1520 cm 1, while the characteristic of the second exothermic phase was the strengthening of the ν(C~C)B/
ν(C~C)Phz band at c.a. 1636 cm 1 which becomes stronger than the ν(C––C)Q/ν(C~C)SQ band at c.a. 1590 cm–1.
For granular PANIs, the band at 1590 cm–1 was stronger than that at 1630 cm–1 for all reaction phases. For all
reaction systems, characteristic feature of the post-propagation phase was strengthening of the ν(C~N+•) band at
1330–1340 cm 1 due to delocalized polarons. For granular PANIs, the band associated with phenazine-like units
at c.a. 1415 cm 1 disappeared after the exothermic phase, while for nanostructured PANIs it was seen until the
end of the reaction. The obtained results are expected to be useful in further investigations of the intermediates/
products and mechanisms of polymerizations of other aromatic amines.",
publisher = "Elsevier",
journal = "Synthetic Metals  Synthetic Metals",
title = "In situ Raman spectroscopy study of the oxidative polymerization of aniline in media of different acidity",
volume = "305",
pages = "117602",
doi = "10.1016/j.synthmet.2024.117602"
}

Janošević-Ležaić, A., Bajuk-Bogdanović, D.,& Ćirić-Marjanović, G.. (2024). In situ Raman spectroscopy study of the oxidative polymerization of aniline in media of different acidity. in Synthetic Metals  Synthetic Metals
Elsevier., 305, 117602.
https://doi.org/10.1016/j.synthmet.2024.117602

Janošević-Ležaić A, Bajuk-Bogdanović D, Ćirić-Marjanović G. In situ Raman spectroscopy study of the oxidative polymerization of aniline in media of different acidity. in Synthetic Metals  Synthetic Metals. 2024;305:117602.
doi:10.1016/j.synthmet.2024.117602 .

Janošević-Ležaić, Aleksandra, Bajuk-Bogdanović, Danica, Ćirić-Marjanović, Gordana, "In situ Raman spectroscopy study of the oxidative polymerization of aniline in media of different acidity" in Synthetic Metals  Synthetic Metals, 305 (2024):117602,
https://doi.org/10.1016/j.synthmet.2024.117602 . .

TY  - JOUR
AU  - Popadić, Daliborka
AU  - Krstić, Jugoslav
AU  - Janošević-Ležaić, Aleksandra
AU  - Popović, Maja
AU  - Milojević-Rakić, Maja
AU  - Ignjatović, Ljubiša
AU  - Bajuk-Bogdanović, Danica
AU  - Gavrilov, Nemanja
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5405
AB  - Reuse and/or recycling of spent adsorbents is taking a central role in modern thinking and catalyzed carbonization is the way forward. Herein we explore the carbonization of adsorbed acetamiprid, in an inert atmosphere, as a way of recycling and producing nitrogen-rich carbon material for potential use in supercapacitors. Added value material and the reuse of the adsorbent were achieved by carbonization at 700 °C under argon. The formation of a nitrogen-doped carbon layer as an active material on the adsorbent, bonded through a C-Si linkage, has been conclusively verified through elemental composition quantification using XPS and EDX measurements. Two-stage catalytic decomposition and condensation of the adsorbed pesticide is followed by TGA and TPD-MS. Attained carbon-based materials give stable Faradaic capacitance with a slight dependency on the number of adsorbing cycles. Capacitance calculated with respect to the adlayer carbon material reaches values as high as 610 F g−1. Galvanostatic Charge/Discharge measurement confirmed the stability of explored materials with a slight increase in capacitance over 1000 cycles. The presented results envisage electroactive materials preparation from environmental pollutants, adding value to spent adsorbents.
PB  - Elsevier B.V.
T2  - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
T1  - Acetamiprid's degradation products and mechanism: Part II – Inert atmosphere and charge storage
VL  - 308
DO  - 10.1016/j.saa.2023.123772
ER  - 

@article{
author = "Popadić, Daliborka and Krstić, Jugoslav and Janošević-Ležaić, Aleksandra and Popović, Maja and Milojević-Rakić, Maja and Ignjatović, Ljubiša and Bajuk-Bogdanović, Danica and Gavrilov, Nemanja",
year = "2024",
abstract = "Reuse and/or recycling of spent adsorbents is taking a central role in modern thinking and catalyzed carbonization is the way forward. Herein we explore the carbonization of adsorbed acetamiprid, in an inert atmosphere, as a way of recycling and producing nitrogen-rich carbon material for potential use in supercapacitors. Added value material and the reuse of the adsorbent were achieved by carbonization at 700 °C under argon. The formation of a nitrogen-doped carbon layer as an active material on the adsorbent, bonded through a C-Si linkage, has been conclusively verified through elemental composition quantification using XPS and EDX measurements. Two-stage catalytic decomposition and condensation of the adsorbed pesticide is followed by TGA and TPD-MS. Attained carbon-based materials give stable Faradaic capacitance with a slight dependency on the number of adsorbing cycles. Capacitance calculated with respect to the adlayer carbon material reaches values as high as 610 F g−1. Galvanostatic Charge/Discharge measurement confirmed the stability of explored materials with a slight increase in capacitance over 1000 cycles. The presented results envisage electroactive materials preparation from environmental pollutants, adding value to spent adsorbents.",
publisher = "Elsevier B.V.",
journal = "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
title = "Acetamiprid's degradation products and mechanism: Part II – Inert atmosphere and charge storage",
volume = "308",
doi = "10.1016/j.saa.2023.123772"
}

Popadić, D., Krstić, J., Janošević-Ležaić, A., Popović, M., Milojević-Rakić, M., Ignjatović, L., Bajuk-Bogdanović, D.,& Gavrilov, N.. (2024). Acetamiprid's degradation products and mechanism: Part II – Inert atmosphere and charge storage. in Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Elsevier B.V.., 308.
https://doi.org/10.1016/j.saa.2023.123772

Popadić D, Krstić J, Janošević-Ležaić A, Popović M, Milojević-Rakić M, Ignjatović L, Bajuk-Bogdanović D, Gavrilov N. Acetamiprid's degradation products and mechanism: Part II – Inert atmosphere and charge storage. in Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 2024;308.
doi:10.1016/j.saa.2023.123772 .

Popadić, Daliborka, Krstić, Jugoslav, Janošević-Ležaić, Aleksandra, Popović, Maja, Milojević-Rakić, Maja, Ignjatović, Ljubiša, Bajuk-Bogdanović, Danica, Gavrilov, Nemanja, "Acetamiprid's degradation products and mechanism: Part II – Inert atmosphere and charge storage" in Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 308 (2024),
https://doi.org/10.1016/j.saa.2023.123772 . .

TY  - JOUR
AU  - Milikić, Jadrank
AU  - Savić, Marjetka
AU  - Janošević-Ležaić, Aleksandra
AU  - Šljukić, Biljana
AU  - Ćirić-Marjanović, Gordana
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5572
AB  - For the first time, composites of metal-organic framework MOF-5 and conjugated polymer polyaniline (PANI), (MOF-5/PANI), prepared using PANI in its conducting (emeraldine salt, ES) or nonconducting form (emeraldine base, EB) at various MOF-5 and PANI mass ratios, were evaluated as electrode materials for the electrochemical detection of cadmium (Cd2+) and lead (Pb2+) ions in aqueous solutions. Testing of individual components of composites, PANI-ES, PANI-EB, and MOF-5, was also performed for comparison. Materials are characterized by Raman spectroscopy, scanning electron microscopy (SEM) and dynamic light scattering (DLS), and their electrochemical behavior was discussed in terms of their zeta potential, structural, morphology, and textural properties. All examined composites showed high electrocatalytic activity for the oxidation of Cd and Pb to Cd2+ and Pb2+, respectively. The MOF/EB-1 composite (71.0 wt.% MOF-5) gave the highest oxidation currents during both individual and simultaneous detection of two heavy metal ions. Current densities recorded with MOF/EB-1 were also higher than those of its individual components, reflecting the synergistic effect where MOF-5 offers high surface area for two heavy metals adsorption and PANI offers a network for electron transfer during metals’ subsequent oxidation. Limits of detection using MOF/EB-1 electrode for Cd2+ and Pb2+ sensing were found to be as low as 0.077 ppm and 0.033 ppm, respectively. Moreover, the well-defined and intense peaks of Cd oxidation to Cd2+ and somewhat lower peaks of Pb oxidation to Pb2+ were observed at voltammograms obtained for the Danube River as a real sample with no pretreatment, which implies that herein tested MOF-5/PANI electrodes could be used as electrochemical sensors for the detection of heavy metal ions in the real water samples.
PB  - MDPI
T2  - Polymers
T1  - Electrochemical Sensing of Cadmium and Lead Ions in Water by MOF-5/PANI Composites
VL  - 16
IS  - 5
SP  - 683
DO  - 10.3390/polym16050683
ER  - 

@article{
author = "Milikić, Jadrank and Savić, Marjetka and Janošević-Ležaić, Aleksandra and Šljukić, Biljana and Ćirić-Marjanović, Gordana",
year = "2024",
abstract = "For the first time, composites of metal-organic framework MOF-5 and conjugated polymer polyaniline (PANI), (MOF-5/PANI), prepared using PANI in its conducting (emeraldine salt, ES) or nonconducting form (emeraldine base, EB) at various MOF-5 and PANI mass ratios, were evaluated as electrode materials for the electrochemical detection of cadmium (Cd2+) and lead (Pb2+) ions in aqueous solutions. Testing of individual components of composites, PANI-ES, PANI-EB, and MOF-5, was also performed for comparison. Materials are characterized by Raman spectroscopy, scanning electron microscopy (SEM) and dynamic light scattering (DLS), and their electrochemical behavior was discussed in terms of their zeta potential, structural, morphology, and textural properties. All examined composites showed high electrocatalytic activity for the oxidation of Cd and Pb to Cd2+ and Pb2+, respectively. The MOF/EB-1 composite (71.0 wt.% MOF-5) gave the highest oxidation currents during both individual and simultaneous detection of two heavy metal ions. Current densities recorded with MOF/EB-1 were also higher than those of its individual components, reflecting the synergistic effect where MOF-5 offers high surface area for two heavy metals adsorption and PANI offers a network for electron transfer during metals’ subsequent oxidation. Limits of detection using MOF/EB-1 electrode for Cd2+ and Pb2+ sensing were found to be as low as 0.077 ppm and 0.033 ppm, respectively. Moreover, the well-defined and intense peaks of Cd oxidation to Cd2+ and somewhat lower peaks of Pb oxidation to Pb2+ were observed at voltammograms obtained for the Danube River as a real sample with no pretreatment, which implies that herein tested MOF-5/PANI electrodes could be used as electrochemical sensors for the detection of heavy metal ions in the real water samples.",
publisher = "MDPI",
journal = "Polymers",
title = "Electrochemical Sensing of Cadmium and Lead Ions in Water by MOF-5/PANI Composites",
volume = "16",
number = "5",
pages = "683",
doi = "10.3390/polym16050683"
}

Milikić, J., Savić, M., Janošević-Ležaić, A., Šljukić, B.,& Ćirić-Marjanović, G.. (2024). Electrochemical Sensing of Cadmium and Lead Ions in Water by MOF-5/PANI Composites. in Polymers
MDPI., 16(5), 683.
https://doi.org/10.3390/polym16050683

Milikić J, Savić M, Janošević-Ležaić A, Šljukić B, Ćirić-Marjanović G. Electrochemical Sensing of Cadmium and Lead Ions in Water by MOF-5/PANI Composites. in Polymers. 2024;16(5):683.
doi:10.3390/polym16050683 .

Milikić, Jadrank, Savić, Marjetka, Janošević-Ležaić, Aleksandra, Šljukić, Biljana, Ćirić-Marjanović, Gordana, "Electrochemical Sensing of Cadmium and Lead Ions in Water by MOF-5/PANI Composites" in Polymers, 16, no. 5 (2024):683,
https://doi.org/10.3390/polym16050683 . .

TY  - JOUR
AU  - Pavun, Leposava
AU  - Janošević-Ležaić, Aleksandra
AU  - Uskoković-Marković, Snežana
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5579
AB  - Abstract
Flavonoids, as plant-derived compounds, were essential active components in traditional
medicine for centuries. Their potential or confirmed effects include antiviral, antimutagenic, antiinflammatory, antibacterial, vasodilatory, and anticancer properties. The promotion of a plantbased diet, along with the benefits of consuming flavonoids, has recently become increasingly
attractive. 3-Hydroxyflavone (3HF) is the structural spine of flavonols, an important subgroup of
flavonoids. Although 3HF itself does not exist in plants per se, it exerts many of its effects because
of its characteristics that allow it to prevent free radical generation. This work is focused on the
characterization of 3HF complexes with zinc(II) and aluminium(III) ions (Zn-3HF and Al-3HF,
respectively). Besides this, a simple, fast, and low-priced spectrophotometric method for 3HF
determination, with very low LOD and LOQ, based on Zn-3HF and Al-3HF formation, was
established. A slight advantage is given to the modification with Al3+ ion on pH 4.91, due to very
low LOD and LOQ values of 1.83×10-7 molL-1
, and 5.50×10-7 molL-1
, respectively, and a high
correlation coefficient, R =0.99986. Furthermore, the antioxidant ability of Zn-3HF, Al-3HF, and
parent 3HF was examined by the ABTS and DPPH tests. They brought the Zn-3HF complex to
the fore as a potential antioxidative agent.
AB  - Flavonoidi, jedinjenja biljnog porekla, vekovima su bili veoma važne aktivne komponente u tradicionalnoj medicini. Veliki broj njihovih potencijalnih ili već potvrđenih efekata uključuje antivirusna, antimutagena, antiinflamatorna, antibakterijska, vazodilatatorna i antikancerogena svojstva. Promovisanje biljne ishrane, uz isticanje koristi konzumiranja flavonoida, u današnje vreme postalo je sve privlačnije. 3-Hidroksiflavon (3HF) je strukturni stub svih flavonola, važne klase flavonoida. Iako sam 3HF ne postoji u biljkama per se, on ispoljava mnoge svoje efekte zahvaljujući osobini da sprečava stvaranja slobodnih radikala. Ovaj rad je fokusiran na karakterizaciju kompleksa 3HF sa jonima cinka(II) i aluminijuma(III) (Zn-3HF i Al-3HF, respektivno). Izvršena je karakterizacija ovih kompleksa i razvijena brza i pristupačna metoda za spektrofotometrijsko određivanje 3HF, na osnovu formiranja kompleksa Zn-3HF i Al-3HF, sa veoma niskim vrednostima LOD i LOQ. Mala prednost je data modifikaciji sa Al3+ na pH 4,91 zbog izuzetno niskih vrednosti LOD i LOQ, 1,83×10-7 mol L-1 , odnosno 5,50×10-7 mol L-1 , kao i visokog koeficijenta korelacije, R=0,99986. Pored toga, antioksidativni kapaciteti sintetizovanih kompleksa Zn-3HF i Al-3HF, kao i samog 3HF, ispitani su DPPH i ABTS testovima i doveli su Zn-3HF kompleks u prvi plan za dalja ispitivanja kao potencijalnog antioksidativnog agensa.
PB  - Beograd : Savez farmaceutskih udruženja Srbije
T2  - Arhiv za farmaciju
T1  - Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles
T1  - Uporedno spektrofotometrijsko određivanje 3-hidroksiflavona bazirano na kompleksima cinka i aluminijuma i njihovi antioksidatni profili
VL  - 74
IS  - 1
SP  - 92
EP  - 104
DO  - 10.5937/arhfarm74-48637
ER  - 

@article{
author = "Pavun, Leposava and Janošević-Ležaić, Aleksandra and Uskoković-Marković, Snežana",
year = "2024",
abstract = "Abstract
Flavonoids, as plant-derived compounds, were essential active components in traditional
medicine for centuries. Their potential or confirmed effects include antiviral, antimutagenic, antiinflammatory, antibacterial, vasodilatory, and anticancer properties. The promotion of a plantbased diet, along with the benefits of consuming flavonoids, has recently become increasingly
attractive. 3-Hydroxyflavone (3HF) is the structural spine of flavonols, an important subgroup of
flavonoids. Although 3HF itself does not exist in plants per se, it exerts many of its effects because
of its characteristics that allow it to prevent free radical generation. This work is focused on the
characterization of 3HF complexes with zinc(II) and aluminium(III) ions (Zn-3HF and Al-3HF,
respectively). Besides this, a simple, fast, and low-priced spectrophotometric method for 3HF
determination, with very low LOD and LOQ, based on Zn-3HF and Al-3HF formation, was
established. A slight advantage is given to the modification with Al3+ ion on pH 4.91, due to very
low LOD and LOQ values of 1.83×10-7 molL-1
, and 5.50×10-7 molL-1
, respectively, and a high
correlation coefficient, R =0.99986. Furthermore, the antioxidant ability of Zn-3HF, Al-3HF, and
parent 3HF was examined by the ABTS and DPPH tests. They brought the Zn-3HF complex to
the fore as a potential antioxidative agent., Flavonoidi, jedinjenja biljnog porekla, vekovima su bili veoma važne aktivne komponente u tradicionalnoj medicini. Veliki broj njihovih potencijalnih ili već potvrđenih efekata uključuje antivirusna, antimutagena, antiinflamatorna, antibakterijska, vazodilatatorna i antikancerogena svojstva. Promovisanje biljne ishrane, uz isticanje koristi konzumiranja flavonoida, u današnje vreme postalo je sve privlačnije. 3-Hidroksiflavon (3HF) je strukturni stub svih flavonola, važne klase flavonoida. Iako sam 3HF ne postoji u biljkama per se, on ispoljava mnoge svoje efekte zahvaljujući osobini da sprečava stvaranja slobodnih radikala. Ovaj rad je fokusiran na karakterizaciju kompleksa 3HF sa jonima cinka(II) i aluminijuma(III) (Zn-3HF i Al-3HF, respektivno). Izvršena je karakterizacija ovih kompleksa i razvijena brza i pristupačna metoda za spektrofotometrijsko određivanje 3HF, na osnovu formiranja kompleksa Zn-3HF i Al-3HF, sa veoma niskim vrednostima LOD i LOQ. Mala prednost je data modifikaciji sa Al3+ na pH 4,91 zbog izuzetno niskih vrednosti LOD i LOQ, 1,83×10-7 mol L-1 , odnosno 5,50×10-7 mol L-1 , kao i visokog koeficijenta korelacije, R=0,99986. Pored toga, antioksidativni kapaciteti sintetizovanih kompleksa Zn-3HF i Al-3HF, kao i samog 3HF, ispitani su DPPH i ABTS testovima i doveli su Zn-3HF kompleks u prvi plan za dalja ispitivanja kao potencijalnog antioksidativnog agensa.",
publisher = "Beograd : Savez farmaceutskih udruženja Srbije",
journal = "Arhiv za farmaciju",
title = "Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles, Uporedno spektrofotometrijsko određivanje 3-hidroksiflavona bazirano na kompleksima cinka i aluminijuma i njihovi antioksidatni profili",
volume = "74",
number = "1",
pages = "92-104",
doi = "10.5937/arhfarm74-48637"
}

Pavun, L., Janošević-Ležaić, A.,& Uskoković-Marković, S.. (2024). Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles. in Arhiv za farmaciju
Beograd : Savez farmaceutskih udruženja Srbije., 74(1), 92-104.
https://doi.org/10.5937/arhfarm74-48637

Pavun L, Janošević-Ležaić A, Uskoković-Marković S. Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles. in Arhiv za farmaciju. 2024;74(1):92-104.
doi:10.5937/arhfarm74-48637 .

Pavun, Leposava, Janošević-Ležaić, Aleksandra, Uskoković-Marković, Snežana, "Comparative spectrophotometric determination of 3-hydroxyflavone based on zinc and aluminium complexes and their antioxidative profiles" in Arhiv za farmaciju, 74, no. 1 (2024):92-104,
https://doi.org/10.5937/arhfarm74-48637 . .

TY  - CONF
AU  - Stojanović, Jevrem
AU  - Zalewski, Przemysław
AU  - Otašević, Biljana
AU  - Zečević, Mira
AU  - Malenović, Anđelija
AU  - Janošević-Ležaić, Aleksandra
AU  - Ranđelović, Dragana
AU  - Protić, Ana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5479
AB  - In the last two decades, there has been a growing awareness of the presence of pharmaceuticals in the aquatic 
environment. Antibiotics are particularly alarming because their occurrence may result in increased antibiotic 
resistance. Difficulties in sample preparation and removal of low concentrations of pharmaceuticals from 
environmental water could be overcome by their adsorption onto novel, non-polluting, and inexpensive 
materials. 
In this study, biochar prepared by pirolysis of biomass at 500°C (BC500) and 800°C (BC800) and activated 
carbon prepared upon treatment with ZnCl2 at 800°C (AC800) were evaluated as potential adsorbents. Ailanthus 
altissima was selected as a source of raw material, leaf, because it is a widespread invasive tree that negatively 
affects biodiversity. Tetracycline hydrochloride was selected as a model substance, since it is an antibiotic 
widely present in environmental water. Central composite design was employed to simultaneously investigate 
the effects of adsorbate solution pH, ionic strength (KCl concentration), and adsorbent mass on removal 
efficiency of all three adsorbents, and to find optimal conditions for studying adsorption kinetics and equilibrium 
on the most promising adsorbent. The removal efficiency and adsorbed mass were calculated from the HPLC UV determined concentration of tetracycline post-adsorption. 
Under optimal conditions (10.18 mg of adsorbent, pH 4.42, and ionic strength 165mM), AC800 showed the 
highest affinity for tetracycline, i.e. 38.22% removal and adsorbed mass of 56.32 mg g-1 compared to 14.57% 
and 21.48 mg g-1 (BC500) and 18.82% and 27.73 mg g-1 (BC800). Removal efficiency of AC800 was strongly 
influenced by the adsorbent mass and solution pH. The kinetics study showed a rapid adsorption process 
(equilibrium attained in 120 minutes), while equilibrium studies revealed a high adsorption capacity for 
tetracycline (131.55 mg g-1). AC800 has been shown to be a promising novel drug adsorbent and should be 
further tested for its suitability in water treatment and sample preparation.
PB  - Uniwersytet Medyczny im. K. Marcinkowskiego w Poznaniu
PB  - Polskie Towarzystwo Farmaceutyczne
PB  - Stowarzyszenie Stop Nielegalnym Farmaceutykom
C3  - IV Poznańska Konferencja Naukowo – Szkoleniowej - „Modern pharmaceutical and biomedical analytics in health care”
T1  - Adsorption of pharmaceuticals by novel carbonaceous materials from the leaves of  Ailanthus altissima (Mill.) Swingle - Case study on the adsorption of tetracycline
SP  - 64
EP  - 64
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5479
ER  - 

@conference{
author = "Stojanović, Jevrem and Zalewski, Przemysław and Otašević, Biljana and Zečević, Mira and Malenović, Anđelija and Janošević-Ležaić, Aleksandra and Ranđelović, Dragana and Protić, Ana",
year = "2023",
abstract = "In the last two decades, there has been a growing awareness of the presence of pharmaceuticals in the aquatic 
environment. Antibiotics are particularly alarming because their occurrence may result in increased antibiotic 
resistance. Difficulties in sample preparation and removal of low concentrations of pharmaceuticals from 
environmental water could be overcome by their adsorption onto novel, non-polluting, and inexpensive 
materials. 
In this study, biochar prepared by pirolysis of biomass at 500°C (BC500) and 800°C (BC800) and activated 
carbon prepared upon treatment with ZnCl2 at 800°C (AC800) were evaluated as potential adsorbents. Ailanthus 
altissima was selected as a source of raw material, leaf, because it is a widespread invasive tree that negatively 
affects biodiversity. Tetracycline hydrochloride was selected as a model substance, since it is an antibiotic 
widely present in environmental water. Central composite design was employed to simultaneously investigate 
the effects of adsorbate solution pH, ionic strength (KCl concentration), and adsorbent mass on removal 
efficiency of all three adsorbents, and to find optimal conditions for studying adsorption kinetics and equilibrium 
on the most promising adsorbent. The removal efficiency and adsorbed mass were calculated from the HPLC UV determined concentration of tetracycline post-adsorption. 
Under optimal conditions (10.18 mg of adsorbent, pH 4.42, and ionic strength 165mM), AC800 showed the 
highest affinity for tetracycline, i.e. 38.22% removal and adsorbed mass of 56.32 mg g-1 compared to 14.57% 
and 21.48 mg g-1 (BC500) and 18.82% and 27.73 mg g-1 (BC800). Removal efficiency of AC800 was strongly 
influenced by the adsorbent mass and solution pH. The kinetics study showed a rapid adsorption process 
(equilibrium attained in 120 minutes), while equilibrium studies revealed a high adsorption capacity for 
tetracycline (131.55 mg g-1). AC800 has been shown to be a promising novel drug adsorbent and should be 
further tested for its suitability in water treatment and sample preparation.",
publisher = "Uniwersytet Medyczny im. K. Marcinkowskiego w Poznaniu, Polskie Towarzystwo Farmaceutyczne, Stowarzyszenie Stop Nielegalnym Farmaceutykom",
journal = "IV Poznańska Konferencja Naukowo – Szkoleniowej - „Modern pharmaceutical and biomedical analytics in health care”",
title = "Adsorption of pharmaceuticals by novel carbonaceous materials from the leaves of  Ailanthus altissima (Mill.) Swingle - Case study on the adsorption of tetracycline",
pages = "64-64",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5479"
}

Stojanović, J., Zalewski, P., Otašević, B., Zečević, M., Malenović, A., Janošević-Ležaić, A., Ranđelović, D.,& Protić, A.. (2023). Adsorption of pharmaceuticals by novel carbonaceous materials from the leaves of  Ailanthus altissima (Mill.) Swingle - Case study on the adsorption of tetracycline. in IV Poznańska Konferencja Naukowo – Szkoleniowej - „Modern pharmaceutical and biomedical analytics in health care”
Uniwersytet Medyczny im. K. Marcinkowskiego w Poznaniu., 64-64.
https://hdl.handle.net/21.15107/rcub_farfar_5479

Stojanović J, Zalewski P, Otašević B, Zečević M, Malenović A, Janošević-Ležaić A, Ranđelović D, Protić A. Adsorption of pharmaceuticals by novel carbonaceous materials from the leaves of  Ailanthus altissima (Mill.) Swingle - Case study on the adsorption of tetracycline. in IV Poznańska Konferencja Naukowo – Szkoleniowej - „Modern pharmaceutical and biomedical analytics in health care”. 2023;:64-64.
https://hdl.handle.net/21.15107/rcub_farfar_5479 .

Stojanović, Jevrem, Zalewski, Przemysław, Otašević, Biljana, Zečević, Mira, Malenović, Anđelija, Janošević-Ležaić, Aleksandra, Ranđelović, Dragana, Protić, Ana, "Adsorption of pharmaceuticals by novel carbonaceous materials from the leaves of  Ailanthus altissima (Mill.) Swingle - Case study on the adsorption of tetracycline" in IV Poznańska Konferencja Naukowo – Szkoleniowej - „Modern pharmaceutical and biomedical analytics in health care” (2023):64-64,
https://hdl.handle.net/21.15107/rcub_farfar_5479 .

TY  - JOUR
AU  - Ranković, Maja
AU  - Jevremović, Anka
AU  - Janošević-Ležaić, Aleksandra
AU  - Arsenijević, Aleksandar
AU  - Rupar, Jelena
AU  - Dobričić, Vladimir
AU  - Nedić Vasiljević, Bojana
AU  - Gavrilov, Nemanja
AU  - Bajuk-Bogdanović, Danica
AU  - Milojević-Rakić, Maja
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4649
AB  - Acridine and its derivatives (9-chloroacridine and 9-aminoacridine) are investigated here, supported on FAU type zeolite Y, as a delivery system of anticancer agents. FTIR/Raman spectroscopy and electron microscopy revealed successful drug loading on the zeolite surface, while spectrofluorimetry was employed for drug quantification. The effects of the tested compounds on cell viability were evaluated using in vitro methylthiazol-tetrazolium (MTT) colorimetric technique against human colorectal carcinoma (cell line HCT-116) and MRC-5 fibroblasts. Zeolite structure remained unchanged during homogeneous drug impregnation with achieved drug loadings in the 18–21 mg/g range. The highest drug release, in the µM concentration range, with favourable kinetics was established for zeolite-supported 9-aminoacridine. The acridine delivery via zeolite carrier is viewed in terms of solvation energy and zeolite adsorption sites. The cytotoxic effect of supported acridines on HCT-116 cells reveals that the zeolite carrier improves toxicity, while the highest efficiency is displayed by zeolite-impregnated 9-aminoacridine. The 9-aminoacridine delivery via zeolite carrier favours healthy tissue preservation while accompanying increased toxicity toward cancer cells. Cytotoxicity results are well correlated with theoretical modelling and release study, providing promising results for applicative purposes.
PB  - MDPI
T2  - Journal of Functional Biomaterials
T1  - Can Zeolite-Supporting Acridines Boost Their Anticancer Performance?
VL  - 14
IS  - 3
DO  - 10.3390/jfb14030173
ER  - 

@article{
author = "Ranković, Maja and Jevremović, Anka and Janošević-Ležaić, Aleksandra and Arsenijević, Aleksandar and Rupar, Jelena and Dobričić, Vladimir and Nedić Vasiljević, Bojana and Gavrilov, Nemanja and Bajuk-Bogdanović, Danica and Milojević-Rakić, Maja",
year = "2023",
abstract = "Acridine and its derivatives (9-chloroacridine and 9-aminoacridine) are investigated here, supported on FAU type zeolite Y, as a delivery system of anticancer agents. FTIR/Raman spectroscopy and electron microscopy revealed successful drug loading on the zeolite surface, while spectrofluorimetry was employed for drug quantification. The effects of the tested compounds on cell viability were evaluated using in vitro methylthiazol-tetrazolium (MTT) colorimetric technique against human colorectal carcinoma (cell line HCT-116) and MRC-5 fibroblasts. Zeolite structure remained unchanged during homogeneous drug impregnation with achieved drug loadings in the 18–21 mg/g range. The highest drug release, in the µM concentration range, with favourable kinetics was established for zeolite-supported 9-aminoacridine. The acridine delivery via zeolite carrier is viewed in terms of solvation energy and zeolite adsorption sites. The cytotoxic effect of supported acridines on HCT-116 cells reveals that the zeolite carrier improves toxicity, while the highest efficiency is displayed by zeolite-impregnated 9-aminoacridine. The 9-aminoacridine delivery via zeolite carrier favours healthy tissue preservation while accompanying increased toxicity toward cancer cells. Cytotoxicity results are well correlated with theoretical modelling and release study, providing promising results for applicative purposes.",
publisher = "MDPI",
journal = "Journal of Functional Biomaterials",
title = "Can Zeolite-Supporting Acridines Boost Their Anticancer Performance?",
volume = "14",
number = "3",
doi = "10.3390/jfb14030173"
}

Ranković, M., Jevremović, A., Janošević-Ležaić, A., Arsenijević, A., Rupar, J., Dobričić, V., Nedić Vasiljević, B., Gavrilov, N., Bajuk-Bogdanović, D.,& Milojević-Rakić, M.. (2023). Can Zeolite-Supporting Acridines Boost Their Anticancer Performance?. in Journal of Functional Biomaterials
MDPI., 14(3).
https://doi.org/10.3390/jfb14030173

Ranković M, Jevremović A, Janošević-Ležaić A, Arsenijević A, Rupar J, Dobričić V, Nedić Vasiljević B, Gavrilov N, Bajuk-Bogdanović D, Milojević-Rakić M. Can Zeolite-Supporting Acridines Boost Their Anticancer Performance?. in Journal of Functional Biomaterials. 2023;14(3).
doi:10.3390/jfb14030173 .

Ranković, Maja, Jevremović, Anka, Janošević-Ležaić, Aleksandra, Arsenijević, Aleksandar, Rupar, Jelena, Dobričić, Vladimir, Nedić Vasiljević, Bojana, Gavrilov, Nemanja, Bajuk-Bogdanović, Danica, Milojević-Rakić, Maja, "Can Zeolite-Supporting Acridines Boost Their Anticancer Performance?" in Journal of Functional Biomaterials, 14, no. 3 (2023),
https://doi.org/10.3390/jfb14030173 . .

TY  - GEN
AU  - Janošević-Ležaić, Aleksandra
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5478
AB  - Elektrohemijski uređaji za skladištenje i konverziju energije su od suštinskog značaja za
iskorištavanje energije proizvedene iz obnovljivih izvora (solarna energija, energija vetra i
hidroenergija) u okviru zelene energetske agende modernog društva. Dizajn materijala elektrode je
ključan za postizanje željenih performansi sistema za skladištenje energije. Tri najčešće istražene
grupe elektrodnog materijala su provodni polimeri, materijali na bazi ugljenika i oksidi prelaznih
metala. Ovaj rad daje pregled primene provodnih polimera u elektrohemijskoj konverziji i
skladištenju energije, gde je fokus stavljen na polianilinu (PANI). PANI, verovatno najpoznatiji
provodni polimer, zahvaljujući širokom spektru poželjnih karakteristika: niska cena, stabilnost,
relativno visoka provodljivost i izuzetna elektrohemijska svojstva, smatra se dobrim elektrodnim
materijalom sa potencijalnom primenom u baterijama, superkondenzatorima i hibridnim sistemima.
PANI, kao aktivna faza, skladišti energiju kroz redoks procese tokom kojih prolazi kroz različita
oksidaciona stanja. Dobro je poznato da se na provodljivost PANI i njegove elektrohemijske
osobine može uticati tipom dopantnog materijala, što zajedno sa mogućnošću sinteze raznovrsne
nanostrukturne morfologije PANI, utiče na njegove performanse u uređajima za skladištenje
energije. Međutim, pseudokapacitivni procesi uključuju bubrenje, skupljanje i pucanje polimera
tokom dopinga/dedopinga naelektrisanim jonima, što dovodi do loše stabilnosti tokom cikliranja.
Pored toga, do razgradnje polimera može doći pri visokim potencijalima usled prekomerne
oksidacije, što ograničava radni potencijal elektrode. U ovom radu dat je osvrt na kompozite
provodnih polimera i materijala kao što su metalni oksidi ili ugljenični materijali, koji pokazuju
značajno poboljšanje u elektrohemijskim performansama u uređajima za skladištenje energije.
Isticanjem veze između fizičkih i hemijskih svostva različitih kompozita ukazano je na koji način
treba razvijati nove matrijale sa poboljšanim performansama u elektrohemijskim izvorima energije.
Poboljšana strukturna stabilnost, optimizovana poroznost i poboljšana električna provodljivost
kompozita dovode do dodatnog skladištenja naelektrisanja i poboljšane kinetike transporta
naeliktrisanja. U priči o primeni provodnih polimera za konverziju enerije, treba pomenuti i
karbonizaciju nanostruktura polimernih prekursornih materijala kao obećavajuće metode za
dobijanje ugljeničnih nanostruktura dopiranih heteroatomom, koje se mogu koristiti kao aktivni
materijali elektrode ili kao delovi kompozitnih elektrodnih materijala.
AB  - Electrochemical devices for storage and conversion of energy are essential for harnessing energy
produced from the renewable sources (solar, wind, and hydro) in a meaningful manner within
green energy agenda of our modern society. The design of electrode material is crucial for reaching
desired performance of the energy storage systems. The three most commonly explored groups of
electrode materials are conductive polymers, carbon-based materials, and transition metal oxides.
This contribution gives an overview of developments in the field of conducting polymers application
in electrochemical energy conversion and storage. Different conducting polymers are explored,
while the focus is set on polyaniline (PANI). PANI, probably the most famous of conducting
polymers, which combines many desirable properties, low cost, environmental stability, relatively high conductivity and outstanding electrochemical properties, is considered as an electrode
material in batteries, (super)capacitors, and hybrid systems. PANI, as the active phase, stores
energy through a redox processes during which PANI passes through different oxidation states. It is
already well known that PANI’s conductivity and its electrochemical properties can be influenced
by the type of dopant, that along with its ability of self-organization in different nanostructured
morphology types affects its performances for energy storage. However, pseudocapacitive
processes involve polymer swelling, shrinkage, and cracking during doping/dedoping by charged
ions, resulting in poor cycling stability. In addition, degradation of polymer can occur at high
potentials due to excessive oxidation, which limits the working potential range. Conductive
polymers show a large improvement in electrochemical performance via composite design, with
significant synergy when combined with materials such as carbon materials or metal oxides. In this
work it is indicated how to develop new composites with improved performance, by emphasizing the
connection between the physical and chemical properties of various composites and their
performance in electrochemical energy sources. Improved structural stability, optimized porosity,
and enhanced electrical conductivity of composites, lead to additional charge storage via improved
charge transport and kinetic behavior. Carbonization of polymeric nanostructures is special feature
which deserves a mention in the energy conversion story, where obtained new heteroatom doped
carbon nanostructures can be used as active electrode materials or as parts of composite electrode
materials..
PB  - Union of Mechanical
PB  - Electrotechnical Engineers
PB  - Technicians of Serbia (SMEITS) Society for Renewable Electrical Power Sources
T2  - 11. Međunarodna konferencija o obnovljivim izvorima električne energije : 11th International Conference on Renewable Electrical Power Sources, Beograd, Zbornik radova, November 02-03
T1  - Polianilin: provodni polimer u uređajima za skladištenje energije
T1  - Polyaniline: conductive polymer in energy storage systems
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5478
ER  - 

@misc{
author = "Janošević-Ležaić, Aleksandra",
year = "2023",
abstract = "Elektrohemijski uređaji za skladištenje i konverziju energije su od suštinskog značaja za
iskorištavanje energije proizvedene iz obnovljivih izvora (solarna energija, energija vetra i
hidroenergija) u okviru zelene energetske agende modernog društva. Dizajn materijala elektrode je
ključan za postizanje željenih performansi sistema za skladištenje energije. Tri najčešće istražene
grupe elektrodnog materijala su provodni polimeri, materijali na bazi ugljenika i oksidi prelaznih
metala. Ovaj rad daje pregled primene provodnih polimera u elektrohemijskoj konverziji i
skladištenju energije, gde je fokus stavljen na polianilinu (PANI). PANI, verovatno najpoznatiji
provodni polimer, zahvaljujući širokom spektru poželjnih karakteristika: niska cena, stabilnost,
relativno visoka provodljivost i izuzetna elektrohemijska svojstva, smatra se dobrim elektrodnim
materijalom sa potencijalnom primenom u baterijama, superkondenzatorima i hibridnim sistemima.
PANI, kao aktivna faza, skladišti energiju kroz redoks procese tokom kojih prolazi kroz različita
oksidaciona stanja. Dobro je poznato da se na provodljivost PANI i njegove elektrohemijske
osobine može uticati tipom dopantnog materijala, što zajedno sa mogućnošću sinteze raznovrsne
nanostrukturne morfologije PANI, utiče na njegove performanse u uređajima za skladištenje
energije. Međutim, pseudokapacitivni procesi uključuju bubrenje, skupljanje i pucanje polimera
tokom dopinga/dedopinga naelektrisanim jonima, što dovodi do loše stabilnosti tokom cikliranja.
Pored toga, do razgradnje polimera može doći pri visokim potencijalima usled prekomerne
oksidacije, što ograničava radni potencijal elektrode. U ovom radu dat je osvrt na kompozite
provodnih polimera i materijala kao što su metalni oksidi ili ugljenični materijali, koji pokazuju
značajno poboljšanje u elektrohemijskim performansama u uređajima za skladištenje energije.
Isticanjem veze između fizičkih i hemijskih svostva različitih kompozita ukazano je na koji način
treba razvijati nove matrijale sa poboljšanim performansama u elektrohemijskim izvorima energije.
Poboljšana strukturna stabilnost, optimizovana poroznost i poboljšana električna provodljivost
kompozita dovode do dodatnog skladištenja naelektrisanja i poboljšane kinetike transporta
naeliktrisanja. U priči o primeni provodnih polimera za konverziju enerije, treba pomenuti i
karbonizaciju nanostruktura polimernih prekursornih materijala kao obećavajuće metode za
dobijanje ugljeničnih nanostruktura dopiranih heteroatomom, koje se mogu koristiti kao aktivni
materijali elektrode ili kao delovi kompozitnih elektrodnih materijala., Electrochemical devices for storage and conversion of energy are essential for harnessing energy
produced from the renewable sources (solar, wind, and hydro) in a meaningful manner within
green energy agenda of our modern society. The design of electrode material is crucial for reaching
desired performance of the energy storage systems. The three most commonly explored groups of
electrode materials are conductive polymers, carbon-based materials, and transition metal oxides.
This contribution gives an overview of developments in the field of conducting polymers application
in electrochemical energy conversion and storage. Different conducting polymers are explored,
while the focus is set on polyaniline (PANI). PANI, probably the most famous of conducting
polymers, which combines many desirable properties, low cost, environmental stability, relatively high conductivity and outstanding electrochemical properties, is considered as an electrode
material in batteries, (super)capacitors, and hybrid systems. PANI, as the active phase, stores
energy through a redox processes during which PANI passes through different oxidation states. It is
already well known that PANI’s conductivity and its electrochemical properties can be influenced
by the type of dopant, that along with its ability of self-organization in different nanostructured
morphology types affects its performances for energy storage. However, pseudocapacitive
processes involve polymer swelling, shrinkage, and cracking during doping/dedoping by charged
ions, resulting in poor cycling stability. In addition, degradation of polymer can occur at high
potentials due to excessive oxidation, which limits the working potential range. Conductive
polymers show a large improvement in electrochemical performance via composite design, with
significant synergy when combined with materials such as carbon materials or metal oxides. In this
work it is indicated how to develop new composites with improved performance, by emphasizing the
connection between the physical and chemical properties of various composites and their
performance in electrochemical energy sources. Improved structural stability, optimized porosity,
and enhanced electrical conductivity of composites, lead to additional charge storage via improved
charge transport and kinetic behavior. Carbonization of polymeric nanostructures is special feature
which deserves a mention in the energy conversion story, where obtained new heteroatom doped
carbon nanostructures can be used as active electrode materials or as parts of composite electrode
materials..",
publisher = "Union of Mechanical, Electrotechnical Engineers, Technicians of Serbia (SMEITS) Society for Renewable Electrical Power Sources",
journal = "11. Međunarodna konferencija o obnovljivim izvorima električne energije : 11th International Conference on Renewable Electrical Power Sources, Beograd, Zbornik radova, November 02-03",
title = "Polianilin: provodni polimer u uređajima za skladištenje energije, Polyaniline: conductive polymer in energy storage systems",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5478"
}

Janošević-Ležaić, A.. (2023). Polianilin: provodni polimer u uređajima za skladištenje energije. in 11. Međunarodna konferencija o obnovljivim izvorima električne energije : 11th International Conference on Renewable Electrical Power Sources, Beograd, Zbornik radova, November 02-03
Union of Mechanical..
https://hdl.handle.net/21.15107/rcub_farfar_5478

Janošević-Ležaić A. Polianilin: provodni polimer u uređajima za skladištenje energije. in 11. Međunarodna konferencija o obnovljivim izvorima električne energije : 11th International Conference on Renewable Electrical Power Sources, Beograd, Zbornik radova, November 02-03. 2023;.
https://hdl.handle.net/21.15107/rcub_farfar_5478 .

Janošević-Ležaić, Aleksandra, "Polianilin: provodni polimer u uređajima za skladištenje energije" in 11. Međunarodna konferencija o obnovljivim izvorima električne energije : 11th International Conference on Renewable Electrical Power Sources, Beograd, Zbornik radova, November 02-03 (2023),
https://hdl.handle.net/21.15107/rcub_farfar_5478 .

TY  - CONF
AU  - Marić, M.
AU  - Ivković, A.
AU  - Ivković, Branka
AU  - Janošević-Ležaić, Aleksandra
AU  - Uskoković-Marković, Snežana
AU  - Savić, J.
AU  - Milojević-Rakić, M.
AU  - Bajuk-Bogdanović, D.
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5448
AB  - ABSTRACT – Organic dyes from industry wastewater pollute water tables. Here proposed environmental 
solution relies on pristine red soil for oxidative degradation of methylene blue dye. Soil analysis comprised 
spectroscopic (FTIR and Raman) and microscopic (SEM/EDS) techniques, while spectrophotometry was 
applied for dye quantification. The dominant soil mineral is kaolinite, while Fe homogeneous distribution 
is witnessed in the γ-FeO(OH) form. Soil/Fenton reagent achieved substantial 93% dye removal. An optimal 
oxidant concentration in the Fenton system is 10 mM. We confirm the excellent performance of pristine 
red soil samples as naturally occurring adsorbents and catalysts in Fenton oxidation of environmental 
pollutants.
PB  - University of Belgrade
PB  - Technical Faculty in Bor
C3  - XV International Mineral Processing and Recycling Conference, 17-19 May 2023, Belgrade, Serbia
T1  - Removal of methylene blue from aqueous solutions using an iron-rich soil
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5448
ER  - 

@conference{
author = "Marić, M. and Ivković, A. and Ivković, Branka and Janošević-Ležaić, Aleksandra and Uskoković-Marković, Snežana and Savić, J. and Milojević-Rakić, M. and Bajuk-Bogdanović, D.",
year = "2023",
abstract = "ABSTRACT – Organic dyes from industry wastewater pollute water tables. Here proposed environmental 
solution relies on pristine red soil for oxidative degradation of methylene blue dye. Soil analysis comprised 
spectroscopic (FTIR and Raman) and microscopic (SEM/EDS) techniques, while spectrophotometry was 
applied for dye quantification. The dominant soil mineral is kaolinite, while Fe homogeneous distribution 
is witnessed in the γ-FeO(OH) form. Soil/Fenton reagent achieved substantial 93% dye removal. An optimal 
oxidant concentration in the Fenton system is 10 mM. We confirm the excellent performance of pristine 
red soil samples as naturally occurring adsorbents and catalysts in Fenton oxidation of environmental 
pollutants.",
publisher = "University of Belgrade, Technical Faculty in Bor",
journal = "XV International Mineral Processing and Recycling Conference, 17-19 May 2023, Belgrade, Serbia",
title = "Removal of methylene blue from aqueous solutions using an iron-rich soil",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5448"
}

Marić, M., Ivković, A., Ivković, B., Janošević-Ležaić, A., Uskoković-Marković, S., Savić, J., Milojević-Rakić, M.,& Bajuk-Bogdanović, D.. (2023). Removal of methylene blue from aqueous solutions using an iron-rich soil. in XV International Mineral Processing and Recycling Conference, 17-19 May 2023, Belgrade, Serbia
University of Belgrade..
https://hdl.handle.net/21.15107/rcub_farfar_5448

Marić M, Ivković A, Ivković B, Janošević-Ležaić A, Uskoković-Marković S, Savić J, Milojević-Rakić M, Bajuk-Bogdanović D. Removal of methylene blue from aqueous solutions using an iron-rich soil. in XV International Mineral Processing and Recycling Conference, 17-19 May 2023, Belgrade, Serbia. 2023;.
https://hdl.handle.net/21.15107/rcub_farfar_5448 .

Marić, M., Ivković, A., Ivković, Branka, Janošević-Ležaić, Aleksandra, Uskoković-Marković, Snežana, Savić, J., Milojević-Rakić, M., Bajuk-Bogdanović, D., "Removal of methylene blue from aqueous solutions using an iron-rich soil" in XV International Mineral Processing and Recycling Conference, 17-19 May 2023, Belgrade, Serbia (2023),
https://hdl.handle.net/21.15107/rcub_farfar_5448 .

TY  - JOUR
AU  - Jevremović, Anka
AU  - Savić, Marjetka
AU  - Janošević-Ležaić, Aleksandra
AU  - Krstić, Jugoslav
AU  - Gavrilov, Nemanja
AU  - Bajuk-Bogdanović, Danica
AU  - Milojević-Rakić, Maja
AU  - Ćirić-Marjanović, Gordana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5342
AB  - The environmental application of the carbonized composites of the Zn-containing metal-organic framework MOF-5 and polyaniline (PANI) in its emeraldine salt and base forms (C-(MOF-5/PANI)) was investigated for the first time. Textural properties and particle size distributions revealed that composites are dominantly mesoporous and nanoscale in nature, while Raman spectroscopy revealed the ZnO phase beneath the carbon matrix. Adsorption of pesticide, dye, and metal cation on C-(MOF-5/PANI) composites in aqueous solutions was evaluated and compared with the behavior of the precursor components, carbonized MOF-5 (cMOF), and carbonized PANIs. A lower MOF-5 content in the precursor, a higher specific surface area, and the pore volume of the composites led to improved adsorption performance for acetamiprid (124 mg/g) and Methylene Blue (135 mg/g). The presence of O/N functional groups in composites is essential for the adsorption of nitrogen-rich pollutants through hydrogen bonding with an estimated monolayer capacity twice as high as that of cMOF. The proton exchange accompanying Cd2+ retention was associated with the Zn/Cd ion exchange, and the highest capacity (9.8 mg/g) was observed for the composite synthesized from the precursor with a high MOF-5 content. The multifunctionality of composites was evidenced in mixtures of pollutants where noticeably better performance for Cd2+ removal was found for the composite compared to cMOF. Competitive binding between three pollutants favored the adsorption of pesticide and dye, thereby hindering to some extent the ion exchange necessary for the removal of metal cations. The results emphasize the importance of the PANI form and MOF-5/PANI weight ratio in precursors for the development of surface, porosity, and active sites in C-(MOF-5/PANI) composites, thus guiding their environmental efficiency. The study also demonstrated that C-(MOF-5/PANI) composites retained studied pollutants much better than carbonized precursor PANIs and showed comparable or better adsorption ability than cMOF.
PB  - MDPI
T2  - Polymers
T1  - Environmental Potential of Carbonized MOF-5/PANI Composites for Pesticide, Dye, and Metal Cations—Can They Actually Retain Them All?
VL  - 15
IS  - 22
DO  - 10.3390/polym15224349
ER  - 

@article{
author = "Jevremović, Anka and Savić, Marjetka and Janošević-Ležaić, Aleksandra and Krstić, Jugoslav and Gavrilov, Nemanja and Bajuk-Bogdanović, Danica and Milojević-Rakić, Maja and Ćirić-Marjanović, Gordana",
year = "2023",
abstract = "The environmental application of the carbonized composites of the Zn-containing metal-organic framework MOF-5 and polyaniline (PANI) in its emeraldine salt and base forms (C-(MOF-5/PANI)) was investigated for the first time. Textural properties and particle size distributions revealed that composites are dominantly mesoporous and nanoscale in nature, while Raman spectroscopy revealed the ZnO phase beneath the carbon matrix. Adsorption of pesticide, dye, and metal cation on C-(MOF-5/PANI) composites in aqueous solutions was evaluated and compared with the behavior of the precursor components, carbonized MOF-5 (cMOF), and carbonized PANIs. A lower MOF-5 content in the precursor, a higher specific surface area, and the pore volume of the composites led to improved adsorption performance for acetamiprid (124 mg/g) and Methylene Blue (135 mg/g). The presence of O/N functional groups in composites is essential for the adsorption of nitrogen-rich pollutants through hydrogen bonding with an estimated monolayer capacity twice as high as that of cMOF. The proton exchange accompanying Cd2+ retention was associated with the Zn/Cd ion exchange, and the highest capacity (9.8 mg/g) was observed for the composite synthesized from the precursor with a high MOF-5 content. The multifunctionality of composites was evidenced in mixtures of pollutants where noticeably better performance for Cd2+ removal was found for the composite compared to cMOF. Competitive binding between three pollutants favored the adsorption of pesticide and dye, thereby hindering to some extent the ion exchange necessary for the removal of metal cations. The results emphasize the importance of the PANI form and MOF-5/PANI weight ratio in precursors for the development of surface, porosity, and active sites in C-(MOF-5/PANI) composites, thus guiding their environmental efficiency. The study also demonstrated that C-(MOF-5/PANI) composites retained studied pollutants much better than carbonized precursor PANIs and showed comparable or better adsorption ability than cMOF.",
publisher = "MDPI",
journal = "Polymers",
title = "Environmental Potential of Carbonized MOF-5/PANI Composites for Pesticide, Dye, and Metal Cations—Can They Actually Retain Them All?",
volume = "15",
number = "22",
doi = "10.3390/polym15224349"
}

Jevremović, A., Savić, M., Janošević-Ležaić, A., Krstić, J., Gavrilov, N., Bajuk-Bogdanović, D., Milojević-Rakić, M.,& Ćirić-Marjanović, G.. (2023). Environmental Potential of Carbonized MOF-5/PANI Composites for Pesticide, Dye, and Metal Cations—Can They Actually Retain Them All?. in Polymers
MDPI., 15(22).
https://doi.org/10.3390/polym15224349

Jevremović A, Savić M, Janošević-Ležaić A, Krstić J, Gavrilov N, Bajuk-Bogdanović D, Milojević-Rakić M, Ćirić-Marjanović G. Environmental Potential of Carbonized MOF-5/PANI Composites for Pesticide, Dye, and Metal Cations—Can They Actually Retain Them All?. in Polymers. 2023;15(22).
doi:10.3390/polym15224349 .

Jevremović, Anka, Savić, Marjetka, Janošević-Ležaić, Aleksandra, Krstić, Jugoslav, Gavrilov, Nemanja, Bajuk-Bogdanović, Danica, Milojević-Rakić, Maja, Ćirić-Marjanović, Gordana, "Environmental Potential of Carbonized MOF-5/PANI Composites for Pesticide, Dye, and Metal Cations—Can They Actually Retain Them All?" in Polymers, 15, no. 22 (2023),
https://doi.org/10.3390/polym15224349 . .

TY  - CONF
AU  - Pavun, Leposava
AU  - Janošević-Ležaić, Aleksandra
AU  - Uskoković-Marković, Snežana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5216
AB  - Flavonoids, widely distributed second metabolites of plants, have a large 
number of functions. Nowadays, with more nature-oriented lifestyle, the role in plants 
and potential benefits for humans and animals became more and more important.1 
3-Hydroxyflavone (3HF) represents the backbone of all flavonols, a 
widespread class of flavonoids. Interestingly, this compound is not found naturally in 
plants. Regardless, 3HF is commonly applied as a model molecule because it 
possesses an excited-state intramolecular proton transfer effect and may serve as a 
fluorescent probe in studies of either membranes or intermembrane proteins. It has 
also been shown that 3HF inhibits metastasis of human osteosarcoma cells and 
reduces tumor growth in vivo. 
With aim to find wider application of 3HF, its complexes with metal ions 
attract the attention of the researchers. Beside the characterization of zinc complex 
with 3HF, we reported the validation of the developed simple and low-cost 
spectrophotometric determination of 3-hydroxyflavone based on its zinc complex. 
Furthermore, the antioxidant capacities of the synthesized complex and 3HF itself 
were tested by the DPPH method, followed by the evaluation of more positive issues 
of zinc 3HF complex. The results of the performed study highlighted the suitability 
of zinc complex 3HF both for spectrophotometric determination, as well as to explore 
future applications of its potent bioactivity.
PB  - Society of Chemists and Technologists of Macedonia
C3  - 26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia
T1  - Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5216
ER  - 

@conference{
author = "Pavun, Leposava and Janošević-Ležaić, Aleksandra and Uskoković-Marković, Snežana",
year = "2023",
abstract = "Flavonoids, widely distributed second metabolites of plants, have a large 
number of functions. Nowadays, with more nature-oriented lifestyle, the role in plants 
and potential benefits for humans and animals became more and more important.1 
3-Hydroxyflavone (3HF) represents the backbone of all flavonols, a 
widespread class of flavonoids. Interestingly, this compound is not found naturally in 
plants. Regardless, 3HF is commonly applied as a model molecule because it 
possesses an excited-state intramolecular proton transfer effect and may serve as a 
fluorescent probe in studies of either membranes or intermembrane proteins. It has 
also been shown that 3HF inhibits metastasis of human osteosarcoma cells and 
reduces tumor growth in vivo. 
With aim to find wider application of 3HF, its complexes with metal ions 
attract the attention of the researchers. Beside the characterization of zinc complex 
with 3HF, we reported the validation of the developed simple and low-cost 
spectrophotometric determination of 3-hydroxyflavone based on its zinc complex. 
Furthermore, the antioxidant capacities of the synthesized complex and 3HF itself 
were tested by the DPPH method, followed by the evaluation of more positive issues 
of zinc 3HF complex. The results of the performed study highlighted the suitability 
of zinc complex 3HF both for spectrophotometric determination, as well as to explore 
future applications of its potent bioactivity.",
publisher = "Society of Chemists and Technologists of Macedonia",
journal = "26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia",
title = "Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5216"
}

Pavun, L., Janošević-Ležaić, A.,& Uskoković-Marković, S.. (2023). Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles. in 26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia
Society of Chemists and Technologists of Macedonia..
https://hdl.handle.net/21.15107/rcub_farfar_5216

Pavun L, Janošević-Ležaić A, Uskoković-Marković S. Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles. in 26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia. 2023;.
https://hdl.handle.net/21.15107/rcub_farfar_5216 .

Pavun, Leposava, Janošević-Ležaić, Aleksandra, Uskoković-Marković, Snežana, "Zinc Complex of 3-Hydroxyflavone: Spectrophotometric  Determination and their Antioxidative Profiles" in 26th Congress of Chemists and Technologists of Macedonia, 20th to 23rd of September 2023, Ohrid , RN Macedonia (2023),
https://hdl.handle.net/21.15107/rcub_farfar_5216 .

TY  - JOUR
AU  - Rupar, Jelena
AU  - Hrnjić, Armin
AU  - Uskoković-Marković, Snežana
AU  - Bajuk-Bogdanović, Danica
AU  - Milojević-Rakić, Maja
AU  - Gavrilov, Nemanja
AU  - Janošević-Ležaić, Aleksandra
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4989
AB  - Electrochemical crosslinking of alginate strands by in situ iron oxidation was explored using a potentiostatic regime. Carbon-based materials co-doped with iron, nitrogen, and/or sulfur were prepared via electrolyte composition variation with a nitrogen-rich compound (rivanol) or through post-treatments with sodium sulfide. Nanometer-sized iron particles were confirmed by transmission and field emission scanning electron microscopy in all samples as a consequence of the homogeneous dispersion of iron in the alginate scaffold and its concomitant growth-limiting effect of alginate chains. Raman spectra confirmed a rise in structural disorder with rivanol/Na2S treatment, which points to more defect sites and edges known to be active sites for oxygen reduction. Fourier transform infrared (FTIR) spectra confirmed the presence of different iron, nitrogen, and sulfur species, with a marked difference between Na2S treated/untreated samples. The most positive onset potential (−0.26 V vs. saturated calomel electrode, SCE) was evidenced for the sample co-doped with N, S, and Fe, surpassing the activity of those with single and/or double doping. The mechanism of oxygen reduction in 0.1 M KOH was dominated by the 2e− reduction pathway at low overpotentials and shifted towards complete 4e− reduction at the most negative explored values. The presented results put forward electrochemically formed alginate gels functionalized by homogeneously dispersed multivalent cations as an excellent starting point in nanomaterial design and engineering.
PB  - MDPI
T2  - Polymers
T1  - Electrochemical Crosslinking of Alginate—Towards Doped Carbons for Oxygen Reduction
VL  - 15
IS  - 15
DO  - 10.3390/polym15153169
ER  - 

@article{
author = "Rupar, Jelena and Hrnjić, Armin and Uskoković-Marković, Snežana and Bajuk-Bogdanović, Danica and Milojević-Rakić, Maja and Gavrilov, Nemanja and Janošević-Ležaić, Aleksandra",
year = "2023",
abstract = "Electrochemical crosslinking of alginate strands by in situ iron oxidation was explored using a potentiostatic regime. Carbon-based materials co-doped with iron, nitrogen, and/or sulfur were prepared via electrolyte composition variation with a nitrogen-rich compound (rivanol) or through post-treatments with sodium sulfide. Nanometer-sized iron particles were confirmed by transmission and field emission scanning electron microscopy in all samples as a consequence of the homogeneous dispersion of iron in the alginate scaffold and its concomitant growth-limiting effect of alginate chains. Raman spectra confirmed a rise in structural disorder with rivanol/Na2S treatment, which points to more defect sites and edges known to be active sites for oxygen reduction. Fourier transform infrared (FTIR) spectra confirmed the presence of different iron, nitrogen, and sulfur species, with a marked difference between Na2S treated/untreated samples. The most positive onset potential (−0.26 V vs. saturated calomel electrode, SCE) was evidenced for the sample co-doped with N, S, and Fe, surpassing the activity of those with single and/or double doping. The mechanism of oxygen reduction in 0.1 M KOH was dominated by the 2e− reduction pathway at low overpotentials and shifted towards complete 4e− reduction at the most negative explored values. The presented results put forward electrochemically formed alginate gels functionalized by homogeneously dispersed multivalent cations as an excellent starting point in nanomaterial design and engineering.",
publisher = "MDPI",
journal = "Polymers",
title = "Electrochemical Crosslinking of Alginate—Towards Doped Carbons for Oxygen Reduction",
volume = "15",
number = "15",
doi = "10.3390/polym15153169"
}

Rupar, J., Hrnjić, A., Uskoković-Marković, S., Bajuk-Bogdanović, D., Milojević-Rakić, M., Gavrilov, N.,& Janošević-Ležaić, A.. (2023). Electrochemical Crosslinking of Alginate—Towards Doped Carbons for Oxygen Reduction. in Polymers
MDPI., 15(15).
https://doi.org/10.3390/polym15153169

Rupar J, Hrnjić A, Uskoković-Marković S, Bajuk-Bogdanović D, Milojević-Rakić M, Gavrilov N, Janošević-Ležaić A. Electrochemical Crosslinking of Alginate—Towards Doped Carbons for Oxygen Reduction. in Polymers. 2023;15(15).
doi:10.3390/polym15153169 .

Rupar, Jelena, Hrnjić, Armin, Uskoković-Marković, Snežana, Bajuk-Bogdanović, Danica, Milojević-Rakić, Maja, Gavrilov, Nemanja, Janošević-Ležaić, Aleksandra, "Electrochemical Crosslinking of Alginate—Towards Doped Carbons for Oxygen Reduction" in Polymers, 15, no. 15 (2023),
https://doi.org/10.3390/polym15153169 . .

TY  - JOUR
AU  - Popadić, Daliborka
AU  - Gavrilov, Nemanja
AU  - Krstić, Jugoslav
AU  - Nedić Vasiljević, Bojana
AU  - Janošević-Ležaić, Aleksandra
AU  - Uskoković-Marković, Snežana
AU  - Milojević-Rakić, Maja
AU  - Bajuk-Bogdanović, Danica
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4882
AB  - Herein we unequivocally identify the mechanism of zeolite-catalysed thermal degradation of pesticide, employing Fourier-transform infrared spectroscopy (FTIR), Raman and mass spectrometry following temperature decomposition (TPDe/MS). We demonstrate that Y zeolite can effectively adsorb a significant amount of acetamiprid both in a single trial (168 mg/g) and in 10 cycles (1249 mg/g) with intermittent thermal regeneration at 300 °C. Sectional vibrational analysis of acetamiprid two-stage thermal degradation is performed for pristine and supported pesticide. The acetamiprid Raman spectral changes appear at 200 °C, while partial carbonization occurs at 250 °C. The gradual disappearance of the FTIR bands of acetamiprid is seen up to 270 °C when two Raman signature bands for carbonised material emerged. The TPDe/MS profiles reveal the evolution of mass fragments - in the first step, cleavage of the C[sbnd]C bond occurs between the aromatic core of the molecule and its tail-end, followed by cleavage of the C[sbnd]N bond. The mechanism of adsorbed acetamiprid degradation follows the same step, at significantly lower temperatures, as the process is catalysed by the interaction of acetamiprid nitrogens and zeolite support. Reduced temperature degradation allows for a quick recovery process that leaves 65% efficacy after 10 cycles. After numerous cycles of recovery, a subsequent one-time heat treatment at 700 °C completely restores initial efficacy. The efficient adsorption, novel details on degradation mechanism and ease of regeneration procedure place the Y zeolite at the forefront of future all-encompassing environmental solutions.
PB  - Elsevier B.V.
T2  - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
T1  - Spectral evidence of acetamiprid's thermal degradation products and mechanism
VL  - 301
IS  - 15
DO  - 10.1016/j.saa.2023.122987
ER  - 

@article{
author = "Popadić, Daliborka and Gavrilov, Nemanja and Krstić, Jugoslav and Nedić Vasiljević, Bojana and Janošević-Ležaić, Aleksandra and Uskoković-Marković, Snežana and Milojević-Rakić, Maja and Bajuk-Bogdanović, Danica",
year = "2023",
abstract = "Herein we unequivocally identify the mechanism of zeolite-catalysed thermal degradation of pesticide, employing Fourier-transform infrared spectroscopy (FTIR), Raman and mass spectrometry following temperature decomposition (TPDe/MS). We demonstrate that Y zeolite can effectively adsorb a significant amount of acetamiprid both in a single trial (168 mg/g) and in 10 cycles (1249 mg/g) with intermittent thermal regeneration at 300 °C. Sectional vibrational analysis of acetamiprid two-stage thermal degradation is performed for pristine and supported pesticide. The acetamiprid Raman spectral changes appear at 200 °C, while partial carbonization occurs at 250 °C. The gradual disappearance of the FTIR bands of acetamiprid is seen up to 270 °C when two Raman signature bands for carbonised material emerged. The TPDe/MS profiles reveal the evolution of mass fragments - in the first step, cleavage of the C[sbnd]C bond occurs between the aromatic core of the molecule and its tail-end, followed by cleavage of the C[sbnd]N bond. The mechanism of adsorbed acetamiprid degradation follows the same step, at significantly lower temperatures, as the process is catalysed by the interaction of acetamiprid nitrogens and zeolite support. Reduced temperature degradation allows for a quick recovery process that leaves 65% efficacy after 10 cycles. After numerous cycles of recovery, a subsequent one-time heat treatment at 700 °C completely restores initial efficacy. The efficient adsorption, novel details on degradation mechanism and ease of regeneration procedure place the Y zeolite at the forefront of future all-encompassing environmental solutions.",
publisher = "Elsevier B.V.",
journal = "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",
title = "Spectral evidence of acetamiprid's thermal degradation products and mechanism",
volume = "301",
number = "15",
doi = "10.1016/j.saa.2023.122987"
}

Popadić, D., Gavrilov, N., Krstić, J., Nedić Vasiljević, B., Janošević-Ležaić, A., Uskoković-Marković, S., Milojević-Rakić, M.,& Bajuk-Bogdanović, D.. (2023). Spectral evidence of acetamiprid's thermal degradation products and mechanism. in Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Elsevier B.V.., 301(15).
https://doi.org/10.1016/j.saa.2023.122987

Popadić D, Gavrilov N, Krstić J, Nedić Vasiljević B, Janošević-Ležaić A, Uskoković-Marković S, Milojević-Rakić M, Bajuk-Bogdanović D. Spectral evidence of acetamiprid's thermal degradation products and mechanism. in Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 2023;301(15).
doi:10.1016/j.saa.2023.122987 .

Popadić, Daliborka, Gavrilov, Nemanja, Krstić, Jugoslav, Nedić Vasiljević, Bojana, Janošević-Ležaić, Aleksandra, Uskoković-Marković, Snežana, Milojević-Rakić, Maja, Bajuk-Bogdanović, Danica, "Spectral evidence of acetamiprid's thermal degradation products and mechanism" in Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 301, no. 15 (2023),
https://doi.org/10.1016/j.saa.2023.122987 . .

TY  - JOUR
AU  - Savić, Marjetka
AU  - Janošević-Ležaić, Aleksandra
AU  - Gavrilov, Nemanja
AU  - Pašti, Igor
AU  - Nedić Vasiljević, Bojana
AU  - Krstić, Jugoslav
AU  - Ćirić-Marjanović, Gordana
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4431
AB  - Composites of carbons with metal oxides and metal sulfides have attracted a lot of interest as materials for energy conversion and storage applications. Herein, we report on novel N,O-doped carbon/ZnO/ZnS and N,O-doped carbon/ZnO composites (generally named C-(MOF-5/PANI)), synthesized by the carbonization of metal–organic framework MOF-5/polyaniline (PANI) composites. The produced C-(MOF-5/PANI)s are comprehensively characterized in terms of composition, molecular and crystalline structure, morphology, electrical conductivity, surface area, and electrochemical behavior. The composition and properties of C-(MOF-5/PANI) composites are dictated by the composition of MOF-5/PANI precursors and the form of PANI (conducting emeraldine salt (ES) or nonconducting emeraldine base). The ZnS phase is formed only with the PANI-ES form due to S-containing counter-ions. XRPD revealed that ZnO and ZnS existed as pure wurtzite crystalline phases. PANI and MOF-5 acted synergistically to produce C-(MOF-5/PANI)s with high SBET (up to 609 m2 g−1), electrical conductivity (up to 0.24 S cm−1), and specific capacitance, Cspec, (up to 238.2 F g−1 at 10 mV s−1). Values of Cspec commensurated with N content in C-(MOF-5/PANI) composites (1–10 wt.%) and overcame Cspec of carbonized individual components PANI and MOF-5. By acid etching treatment of C-(MOF-5/PANI), SBET and Cspec increased to 1148 m2 g−1 and 341 F g−1, respectively. The developed composites represent promising electrode materials for supercapacitors.
PB  - MDPI
T2  - Materials
T1  - Carbonization of MOF-5/Polyaniline Composites to N,O-Doped Carbon/ZnO/ZnS and N,O-Doped Carbon/ZnO Composites with High Specific Capacitance, Specific Surface Area and Electrical Conductivity
VL  - 16
IS  - 3
DO  - 10.3390/ma16031018
ER  - 

@article{
author = "Savić, Marjetka and Janošević-Ležaić, Aleksandra and Gavrilov, Nemanja and Pašti, Igor and Nedić Vasiljević, Bojana and Krstić, Jugoslav and Ćirić-Marjanović, Gordana",
year = "2023",
abstract = "Composites of carbons with metal oxides and metal sulfides have attracted a lot of interest as materials for energy conversion and storage applications. Herein, we report on novel N,O-doped carbon/ZnO/ZnS and N,O-doped carbon/ZnO composites (generally named C-(MOF-5/PANI)), synthesized by the carbonization of metal–organic framework MOF-5/polyaniline (PANI) composites. The produced C-(MOF-5/PANI)s are comprehensively characterized in terms of composition, molecular and crystalline structure, morphology, electrical conductivity, surface area, and electrochemical behavior. The composition and properties of C-(MOF-5/PANI) composites are dictated by the composition of MOF-5/PANI precursors and the form of PANI (conducting emeraldine salt (ES) or nonconducting emeraldine base). The ZnS phase is formed only with the PANI-ES form due to S-containing counter-ions. XRPD revealed that ZnO and ZnS existed as pure wurtzite crystalline phases. PANI and MOF-5 acted synergistically to produce C-(MOF-5/PANI)s with high SBET (up to 609 m2 g−1), electrical conductivity (up to 0.24 S cm−1), and specific capacitance, Cspec, (up to 238.2 F g−1 at 10 mV s−1). Values of Cspec commensurated with N content in C-(MOF-5/PANI) composites (1–10 wt.%) and overcame Cspec of carbonized individual components PANI and MOF-5. By acid etching treatment of C-(MOF-5/PANI), SBET and Cspec increased to 1148 m2 g−1 and 341 F g−1, respectively. The developed composites represent promising electrode materials for supercapacitors.",
publisher = "MDPI",
journal = "Materials",
title = "Carbonization of MOF-5/Polyaniline Composites to N,O-Doped Carbon/ZnO/ZnS and N,O-Doped Carbon/ZnO Composites with High Specific Capacitance, Specific Surface Area and Electrical Conductivity",
volume = "16",
number = "3",
doi = "10.3390/ma16031018"
}

Savić, M., Janošević-Ležaić, A., Gavrilov, N., Pašti, I., Nedić Vasiljević, B., Krstić, J.,& Ćirić-Marjanović, G.. (2023). Carbonization of MOF-5/Polyaniline Composites to N,O-Doped Carbon/ZnO/ZnS and N,O-Doped Carbon/ZnO Composites with High Specific Capacitance, Specific Surface Area and Electrical Conductivity. in Materials
MDPI., 16(3).
https://doi.org/10.3390/ma16031018

Savić M, Janošević-Ležaić A, Gavrilov N, Pašti I, Nedić Vasiljević B, Krstić J, Ćirić-Marjanović G. Carbonization of MOF-5/Polyaniline Composites to N,O-Doped Carbon/ZnO/ZnS and N,O-Doped Carbon/ZnO Composites with High Specific Capacitance, Specific Surface Area and Electrical Conductivity. in Materials. 2023;16(3).
doi:10.3390/ma16031018 .

Savić, Marjetka, Janošević-Ležaić, Aleksandra, Gavrilov, Nemanja, Pašti, Igor, Nedić Vasiljević, Bojana, Krstić, Jugoslav, Ćirić-Marjanović, Gordana, "Carbonization of MOF-5/Polyaniline Composites to N,O-Doped Carbon/ZnO/ZnS and N,O-Doped Carbon/ZnO Composites with High Specific Capacitance, Specific Surface Area and Electrical Conductivity" in Materials, 16, no. 3 (2023),
https://doi.org/10.3390/ma16031018 . .

TY  - JOUR
AU  - Rupar, Jelena
AU  - Tekić, Danijela
AU  - Janošević-Ležaić, Aleksandra
AU  - Upadhyay, Kush K.
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4419
AB  - Due to the limited reaction rate of the oxygen reduction reaction (ORR), it is considered as a limiting factor in the performance of fuel cells and metal-air batteries. Platinum is considered the benchmark catalyst for ORR; however, the scarcity of platinum, its high price, the drift phenomenon, its insufficient durability, and its susceptibility to gas poisoning are the reasons for the constant search for new ORR catalysts. Carbon-based catalysts show exceptional promise in this respect considering economic profitability and activity, and, in addition, they have favorable conductivity and often a large specific surface area. The use of chitin, cellulose, lignin, coconut shell particles, shrimp shells, and even hair for this purpose was reported, as they had similar electrochemical activity regarding Pt. Alginate, a natural polymer and a constituent of brown algae, can be successfully used to obtain carbon materials that catalyze ORR. In addition, metal atomic-level catalysts and metal N-doped porous carbon materials, obtained from sodium alginate as a precursor, have been proposed as efficient electrocatalysts for ORR. Except for alginate, other biopolymers have been reported to play an important role in the preparation of ORR catalysts. In this review, recent advances regarding biopolymer-derived ORR catalysts are summarized, with a focus on alginate as a source.
PB  - MDPI
T2  - Catalysts
T1  - ORR Catalysts Derived from Biopolymers
VL  - 13
IS  - 1
DO  - 10.3390/catal13010080
ER  - 

@article{
author = "Rupar, Jelena and Tekić, Danijela and Janošević-Ležaić, Aleksandra and Upadhyay, Kush K.",
year = "2023",
abstract = "Due to the limited reaction rate of the oxygen reduction reaction (ORR), it is considered as a limiting factor in the performance of fuel cells and metal-air batteries. Platinum is considered the benchmark catalyst for ORR; however, the scarcity of platinum, its high price, the drift phenomenon, its insufficient durability, and its susceptibility to gas poisoning are the reasons for the constant search for new ORR catalysts. Carbon-based catalysts show exceptional promise in this respect considering economic profitability and activity, and, in addition, they have favorable conductivity and often a large specific surface area. The use of chitin, cellulose, lignin, coconut shell particles, shrimp shells, and even hair for this purpose was reported, as they had similar electrochemical activity regarding Pt. Alginate, a natural polymer and a constituent of brown algae, can be successfully used to obtain carbon materials that catalyze ORR. In addition, metal atomic-level catalysts and metal N-doped porous carbon materials, obtained from sodium alginate as a precursor, have been proposed as efficient electrocatalysts for ORR. Except for alginate, other biopolymers have been reported to play an important role in the preparation of ORR catalysts. In this review, recent advances regarding biopolymer-derived ORR catalysts are summarized, with a focus on alginate as a source.",
publisher = "MDPI",
journal = "Catalysts",
title = "ORR Catalysts Derived from Biopolymers",
volume = "13",
number = "1",
doi = "10.3390/catal13010080"
}

Rupar, J., Tekić, D., Janošević-Ležaić, A.,& Upadhyay, K. K.. (2023). ORR Catalysts Derived from Biopolymers. in Catalysts
MDPI., 13(1).
https://doi.org/10.3390/catal13010080

Rupar J, Tekić D, Janošević-Ležaić A, Upadhyay KK. ORR Catalysts Derived from Biopolymers. in Catalysts. 2023;13(1).
doi:10.3390/catal13010080 .

Rupar, Jelena, Tekić, Danijela, Janošević-Ležaić, Aleksandra, Upadhyay, Kush K., "ORR Catalysts Derived from Biopolymers" in Catalysts, 13, no. 1 (2023),
https://doi.org/10.3390/catal13010080 . .

TY  - CONF
AU  - Gledović, Ana
AU  - Janošević-Ležaić, Aleksandra
AU  - Savić, Snežana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4574
AB  - In the past twenty years plant oils derived from food industry byproducts have been
in focus due to the ecological and economic reasons. For example, raspberry seed oil – RSO
(Rubus idaeus, Rosaceae), abundant with bioactive compounds such as polyunsaturated fatty
acids, carotenoids, tocopherols and phenolic compounds, is recommended for antioxidant and
UV-protective skincare (1). RSO application is limited by poor oxidative stability, thus this
research aimed at its stabilization with nanoemulsion – NE carrier. Firstly, total carotenoid
and phenolic content of RSO was determined, followed by determination of its oxidative
status by tracking relevant parameters (peroxide value – PV, p-anisidine value – PA, and
thiobarbituric reactive substances – TBARS) (2) during one month of storage. NEs were
prepared with the polyglycerol ester-based natural surfactants by employing phase
inversion composition method, with or without RSO and antioxidants: synthetic (butylated
hydroxytoluene – BHT or ethylenediaminetetraacetic acid, disodium salt – Na 2EDTA), or
sessile oak acorn extract (Quercus petraea, Fagaceae). NEs' physiochemical characterization
included droplet size distribution analysis, electrical conductivity and pH value
measurements, followed by measurement of primary and secondary oxidation products
(lipid hydroperoxides – LH and TBARS, respectively). It was found that RSOs' oxidative
stability was significantly improved when stored at refrigerator after opening or by adding
BHT (PV˂10, PA˂6, % INH TBARS >80%). NEs were semitransparent (with very small
droplets ˂70 nm) and stable at 25 and 40ºC, while drastic formation of oxidative products
was avoided by employing BHT or Na2EDTA, or by using oak extract as natural stabilizer.
AB  - U poslednjih dvadeset godina, usled ekoloških i ekonomskih razloga u fokusu
istraživanja su biljna ulja koja se dobijaju od nusproizvoda prehrambene industrjje. Na
primer, ulje semena maline (Rubus idaeus, Rosaceae), koje obiluje bioaktivnim sastojcima
kao što su polinezasićene masne kiseline (linolna i linolenska), karotenoidi, tokoferoli i
fenolna jedinjenja, preporučuje se za negu,antioksidativnu i UV-zaštitu kože (1). Primenu ulja
maline ograničava loša oksidativna stabilnost, te je cilj ovog istraživanja bila njegova
stabilizacija primenom nanoemulzije (NE), i/ili antioksidanata. Prvo je određivan sadržaj
ukupnih karotenoida i fenola, a zatim oksidativni status ulja maline praćenjem relevantnih
parametara (peroksidni broj – PB, p-anisidinski broj – PA i sadržaj reaktivnih supstanci
tiobarbiturne kiseline – TBARS) (2), tokom mesec dana čuvanja. NEs su pripremljene na bazi
novijih prirodnih poliglicerilskih estara pomoću metode inverzije faza, bezili sa dodatkom ulja
semena maline i antioksidanata: sintetskih (butilhidroksitoluen – BHT ili dinatrijumova so
etilendiamintetrasirćetne kiseline – Na 2EDTA), ili prirodnog ekstrakta žira hrasta kitnjaka
(Quercus petraea, Fagaceae). Fizičkohemijska karakterizacija NEs izvršena je analizom
distribucije veličina kapi, merenjem električne provodljivosti i pH vrednosti, te određivanjem
primarnih i sekundarnih produkata oksidacije (lipidnih hidroperoksida – LH i TBARS
supstanci, redom). Nađeno je da se oksidativna stabilnost ulja maline značajno poboljšala
čuvanjem u frižideru nakon otvaranja ili dodatkom BHT-a (PB˂10, PA˂6, % INH TBARS >80%).
Dobijene NEs su bile polutransparentne (usled malih veličina kapi ˂70 nm) i stabilne na 25 i
40ºC, a drastičan porast oksidacionih produkata je uspešno inhibiran upotrebom BHT-a ili
Na 2 EDTA, kao i pomoćuekstrakta hrasta kitnjaka kao potencijalnog prirodnog stabilizatora.
PB  - Savez farmaceutskih udruženja Srbije (SFUS)
C3  - Arhiv za farmaciju
T1  - Influence of nanoemulsfication, antioxidants and temperature on oxidative stability of red rapsberry seed oil for skin application
T1  - Procena uticaja nanoemulzifikacije, antioksidanata i temperature na oksidativnu stabilnost ulja semena maline za primenu na koži
VL  - 72
IS  - 4 suplement
SP  - S420
EP  - S421
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4574
ER  - 

@conference{
author = "Gledović, Ana and Janošević-Ležaić, Aleksandra and Savić, Snežana",
year = "2022",
abstract = "In the past twenty years plant oils derived from food industry byproducts have been
in focus due to the ecological and economic reasons. For example, raspberry seed oil – RSO
(Rubus idaeus, Rosaceae), abundant with bioactive compounds such as polyunsaturated fatty
acids, carotenoids, tocopherols and phenolic compounds, is recommended for antioxidant and
UV-protective skincare (1). RSO application is limited by poor oxidative stability, thus this
research aimed at its stabilization with nanoemulsion – NE carrier. Firstly, total carotenoid
and phenolic content of RSO was determined, followed by determination of its oxidative
status by tracking relevant parameters (peroxide value – PV, p-anisidine value – PA, and
thiobarbituric reactive substances – TBARS) (2) during one month of storage. NEs were
prepared with the polyglycerol ester-based natural surfactants by employing phase
inversion composition method, with or without RSO and antioxidants: synthetic (butylated
hydroxytoluene – BHT or ethylenediaminetetraacetic acid, disodium salt – Na 2EDTA), or
sessile oak acorn extract (Quercus petraea, Fagaceae). NEs' physiochemical characterization
included droplet size distribution analysis, electrical conductivity and pH value
measurements, followed by measurement of primary and secondary oxidation products
(lipid hydroperoxides – LH and TBARS, respectively). It was found that RSOs' oxidative
stability was significantly improved when stored at refrigerator after opening or by adding
BHT (PV˂10, PA˂6, % INH TBARS >80%). NEs were semitransparent (with very small
droplets ˂70 nm) and stable at 25 and 40ºC, while drastic formation of oxidative products
was avoided by employing BHT or Na2EDTA, or by using oak extract as natural stabilizer., U poslednjih dvadeset godina, usled ekoloških i ekonomskih razloga u fokusu
istraživanja su biljna ulja koja se dobijaju od nusproizvoda prehrambene industrjje. Na
primer, ulje semena maline (Rubus idaeus, Rosaceae), koje obiluje bioaktivnim sastojcima
kao što su polinezasićene masne kiseline (linolna i linolenska), karotenoidi, tokoferoli i
fenolna jedinjenja, preporučuje se za negu,antioksidativnu i UV-zaštitu kože (1). Primenu ulja
maline ograničava loša oksidativna stabilnost, te je cilj ovog istraživanja bila njegova
stabilizacija primenom nanoemulzije (NE), i/ili antioksidanata. Prvo je određivan sadržaj
ukupnih karotenoida i fenola, a zatim oksidativni status ulja maline praćenjem relevantnih
parametara (peroksidni broj – PB, p-anisidinski broj – PA i sadržaj reaktivnih supstanci
tiobarbiturne kiseline – TBARS) (2), tokom mesec dana čuvanja. NEs su pripremljene na bazi
novijih prirodnih poliglicerilskih estara pomoću metode inverzije faza, bezili sa dodatkom ulja
semena maline i antioksidanata: sintetskih (butilhidroksitoluen – BHT ili dinatrijumova so
etilendiamintetrasirćetne kiseline – Na 2EDTA), ili prirodnog ekstrakta žira hrasta kitnjaka
(Quercus petraea, Fagaceae). Fizičkohemijska karakterizacija NEs izvršena je analizom
distribucije veličina kapi, merenjem električne provodljivosti i pH vrednosti, te određivanjem
primarnih i sekundarnih produkata oksidacije (lipidnih hidroperoksida – LH i TBARS
supstanci, redom). Nađeno je da se oksidativna stabilnost ulja maline značajno poboljšala
čuvanjem u frižideru nakon otvaranja ili dodatkom BHT-a (PB˂10, PA˂6, % INH TBARS >80%).
Dobijene NEs su bile polutransparentne (usled malih veličina kapi ˂70 nm) i stabilne na 25 i
40ºC, a drastičan porast oksidacionih produkata je uspešno inhibiran upotrebom BHT-a ili
Na 2 EDTA, kao i pomoćuekstrakta hrasta kitnjaka kao potencijalnog prirodnog stabilizatora.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Influence of nanoemulsfication, antioxidants and temperature on oxidative stability of red rapsberry seed oil for skin application, Procena uticaja nanoemulzifikacije, antioksidanata i temperature na oksidativnu stabilnost ulja semena maline za primenu na koži",
volume = "72",
number = "4 suplement",
pages = "S420-S421",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4574"
}

Gledović, A., Janošević-Ležaić, A.,& Savić, S.. (2022). Influence of nanoemulsfication, antioxidants and temperature on oxidative stability of red rapsberry seed oil for skin application. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije (SFUS)., 72(4 suplement), S420-S421.
https://hdl.handle.net/21.15107/rcub_farfar_4574

Gledović A, Janošević-Ležaić A, Savić S. Influence of nanoemulsfication, antioxidants and temperature on oxidative stability of red rapsberry seed oil for skin application. in Arhiv za farmaciju. 2022;72(4 suplement):S420-S421.
https://hdl.handle.net/21.15107/rcub_farfar_4574 .

Gledović, Ana, Janošević-Ležaić, Aleksandra, Savić, Snežana, "Influence of nanoemulsfication, antioxidants and temperature on oxidative stability of red rapsberry seed oil for skin application" in Arhiv za farmaciju, 72, no. 4 suplement (2022):S420-S421,
https://hdl.handle.net/21.15107/rcub_farfar_4574 .

TY  - JOUR
AU  - Gledović, Ana
AU  - Janošević-Ležaić, Aleksandra
AU  - Tamburić, Slobodanka
AU  - Savić, Snežana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4300
AB  - The aim of this study was to assess and improve the oxidative stability of red raspberry seed oil–RO, a potential topical ingredient derived from food industry by-products, on its own and when incorporated in low energy nanoemulsion (NE). The RO’s oxidative stability was assessed at 5, 25, and 40 °C during one month of storage and expressed in: peroxide value, p-anisidine, and thiobarbituric reactive substances—TBARS value, while for NEs, lipid hydroperoxides and TBARS values were monitored. Both synthetic (butylated hydroxytoluene—BHT and ethylenediaminetetraacetic acid—EDTA), and natural (oregano essential oil—ORE and oak fruit extract—OAK) antioxidants were used. Pure RO and RO with BHT or ORE were stable at 5 °C and 25 °C, but at 40 °C BHT showed only moderate protection, while ORE was prooxidant. NEs prepared with new biodegradable polyglycerol esters-based surfactants, with droplet sizes of < 50 nm and narrow size distribution, showed improved physicochemical stability at room temperature, and especially at 40 °C, compared to NEs with polysorbate 80, which required the addition of antioxidants to preserve their stability. Natural antioxidants ORE and OAK were compatible with all NEs; therefore, their use is proposed as an effective alternative to synthetic antioxidants.
PB  - MDPI
T2  - Antioxidants
T1  - Red Raspberry Seed Oil Low Energy Nanoemulsions: Influence of Surfactants, Antioxidants, and Temperature on Oxidative Stability
VL  - 11
IS  - 10
DO  - 10.3390/antiox11101898
ER  - 

@article{
author = "Gledović, Ana and Janošević-Ležaić, Aleksandra and Tamburić, Slobodanka and Savić, Snežana",
year = "2022",
abstract = "The aim of this study was to assess and improve the oxidative stability of red raspberry seed oil–RO, a potential topical ingredient derived from food industry by-products, on its own and when incorporated in low energy nanoemulsion (NE). The RO’s oxidative stability was assessed at 5, 25, and 40 °C during one month of storage and expressed in: peroxide value, p-anisidine, and thiobarbituric reactive substances—TBARS value, while for NEs, lipid hydroperoxides and TBARS values were monitored. Both synthetic (butylated hydroxytoluene—BHT and ethylenediaminetetraacetic acid—EDTA), and natural (oregano essential oil—ORE and oak fruit extract—OAK) antioxidants were used. Pure RO and RO with BHT or ORE were stable at 5 °C and 25 °C, but at 40 °C BHT showed only moderate protection, while ORE was prooxidant. NEs prepared with new biodegradable polyglycerol esters-based surfactants, with droplet sizes of < 50 nm and narrow size distribution, showed improved physicochemical stability at room temperature, and especially at 40 °C, compared to NEs with polysorbate 80, which required the addition of antioxidants to preserve their stability. Natural antioxidants ORE and OAK were compatible with all NEs; therefore, their use is proposed as an effective alternative to synthetic antioxidants.",
publisher = "MDPI",
journal = "Antioxidants",
title = "Red Raspberry Seed Oil Low Energy Nanoemulsions: Influence of Surfactants, Antioxidants, and Temperature on Oxidative Stability",
volume = "11",
number = "10",
doi = "10.3390/antiox11101898"
}

Gledović, A., Janošević-Ležaić, A., Tamburić, S.,& Savić, S.. (2022). Red Raspberry Seed Oil Low Energy Nanoemulsions: Influence of Surfactants, Antioxidants, and Temperature on Oxidative Stability. in Antioxidants
MDPI., 11(10).
https://doi.org/10.3390/antiox11101898

Gledović A, Janošević-Ležaić A, Tamburić S, Savić S. Red Raspberry Seed Oil Low Energy Nanoemulsions: Influence of Surfactants, Antioxidants, and Temperature on Oxidative Stability. in Antioxidants. 2022;11(10).
doi:10.3390/antiox11101898 .

Gledović, Ana, Janošević-Ležaić, Aleksandra, Tamburić, Slobodanka, Savić, Snežana, "Red Raspberry Seed Oil Low Energy Nanoemulsions: Influence of Surfactants, Antioxidants, and Temperature on Oxidative Stability" in Antioxidants, 11, no. 10 (2022),
https://doi.org/10.3390/antiox11101898 . .

TY  - JOUR
AU  - Gledović, Ana
AU  - Bajuk-Bogdanović, Danica
AU  - Uskoković-Marković, Snežana
AU  - Pavun, Leposava
AU  - Savić, Snežana
AU  - Janošević-Ležaić, Aleksandra
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4170
AB  - In this study several essential oils (EOs): basil - BA, lemon balm - LB and oregano - OR were incorporated into nanoemulsions (NEs) as prospective carriers for natural and sensitive bioactives. NEs were prepared via the phase inversion composition (PIC) method, which is an energy-efficient cold process. Physicochemical stability of NEs was confirmed by particle size distribution analysis, electrical conductivity and pH value measurements, as well as by optical microscopy observations. The type of EO and the surfactant and oil mix concentration were found to be crucial factors governing the NE properties and stability. Raman spectra of the EOs confirmed main active ingredients and provided detection of interactions with the nanocarrier, which is a novel application of this technique. The antioxidant activity towards DPPH radical in methanol was concentration-dependent with a similar trend for individual oils and oil-loaded NEs (OR> LB> BA). However, the ABTS test in an aqueous medium revealed notable change in the order of activity after EO nanonisation at higher EO concentrations. Overall, it was found that OR-NE was the most effective and stable system, since OR acted as a co-stabiliser in the NE formulation, and its remarkably high antioxidant activity was successfully preserved during 6 months of storage.
AB  - U ovoj studiji nekoliko različitih etarskih ulja (EU): bosiljak – BO, matičnjak – MA i origano – OR inkor-
porirano je u nanoemulzije (NE) kao potencijalne nosače za prirodne i osetljive bioaktivne sastojke. NE
su pripremljene pomoću metode inverzije faza (engl. phase inversion composition – PIC method) koja
predstavlja niskoenergetski i ekonomičan postupak izrade. Fizičkohemijska stabilnost nanoemulzija
potvrđena je analizom raspodele veličina kapi, merenjem električne provodljivosti i pH vrednosti, kao i
optičkom mikroskopijom. Nađeno je da su vrsta EU i koncentracija smeše surfaktanata i uljane faze dva
ključna faktora koja su uticala na karakteristike i stabilnost dobijenih emulzija. Tehnikom Ramanske
spektroskopije potvrđeni su glavni aktivni sastojci etarskih ulja i detektovane su moguće interakcije sa
nanonosačem, što predstavlja noviju primenu pomenute tehnike. Pokazano je da antioksidantna
aktivnost prema DPPH radikalu u metanolu zavisi od koncentracije, sa sličnim trendom za čista etarska
ulja i za nanoemulzije sa uljima (OR> MA> BO). Međutim, ABTS test u vodenoj sredini pokazao je izrazite
promene u redosledu aktivnosti sa povećanjem koncentracije EU i nakon nanonizacije EU. Generalno,
dokazano je da je OR-NE najefikasniji i najstabiliniji sistem, s obzirom da je ulje origana ispoljilo ulogu
kostabilizatora u formulaciji, uz istovremeno očuvanje njegove veoma visoke antioksidantne aktivnosti
u obliku nanoemulzije, tokom 6 meseci čuvanja.
PB  - Association of the Chemical Engineers of Serbia
T2  - Hemijska industrija
T1  - Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection
T1  - Niskoenergetske nanoemulzije kao nosači za etarska ulja u topikalnim formulacijama za antioksidantnu zaštitu kože
VL  - 76
IS  - 1
SP  - 29
EP  - 42
DO  - 10.2298/HEMIND210509004G
ER  - 

@article{
author = "Gledović, Ana and Bajuk-Bogdanović, Danica and Uskoković-Marković, Snežana and Pavun, Leposava and Savić, Snežana and Janošević-Ležaić, Aleksandra",
year = "2022",
abstract = "In this study several essential oils (EOs): basil - BA, lemon balm - LB and oregano - OR were incorporated into nanoemulsions (NEs) as prospective carriers for natural and sensitive bioactives. NEs were prepared via the phase inversion composition (PIC) method, which is an energy-efficient cold process. Physicochemical stability of NEs was confirmed by particle size distribution analysis, electrical conductivity and pH value measurements, as well as by optical microscopy observations. The type of EO and the surfactant and oil mix concentration were found to be crucial factors governing the NE properties and stability. Raman spectra of the EOs confirmed main active ingredients and provided detection of interactions with the nanocarrier, which is a novel application of this technique. The antioxidant activity towards DPPH radical in methanol was concentration-dependent with a similar trend for individual oils and oil-loaded NEs (OR> LB> BA). However, the ABTS test in an aqueous medium revealed notable change in the order of activity after EO nanonisation at higher EO concentrations. Overall, it was found that OR-NE was the most effective and stable system, since OR acted as a co-stabiliser in the NE formulation, and its remarkably high antioxidant activity was successfully preserved during 6 months of storage., U ovoj studiji nekoliko različitih etarskih ulja (EU): bosiljak – BO, matičnjak – MA i origano – OR inkor-
porirano je u nanoemulzije (NE) kao potencijalne nosače za prirodne i osetljive bioaktivne sastojke. NE
su pripremljene pomoću metode inverzije faza (engl. phase inversion composition – PIC method) koja
predstavlja niskoenergetski i ekonomičan postupak izrade. Fizičkohemijska stabilnost nanoemulzija
potvrđena je analizom raspodele veličina kapi, merenjem električne provodljivosti i pH vrednosti, kao i
optičkom mikroskopijom. Nađeno je da su vrsta EU i koncentracija smeše surfaktanata i uljane faze dva
ključna faktora koja su uticala na karakteristike i stabilnost dobijenih emulzija. Tehnikom Ramanske
spektroskopije potvrđeni su glavni aktivni sastojci etarskih ulja i detektovane su moguće interakcije sa
nanonosačem, što predstavlja noviju primenu pomenute tehnike. Pokazano je da antioksidantna
aktivnost prema DPPH radikalu u metanolu zavisi od koncentracije, sa sličnim trendom za čista etarska
ulja i za nanoemulzije sa uljima (OR> MA> BO). Međutim, ABTS test u vodenoj sredini pokazao je izrazite
promene u redosledu aktivnosti sa povećanjem koncentracije EU i nakon nanonizacije EU. Generalno,
dokazano je da je OR-NE najefikasniji i najstabiliniji sistem, s obzirom da je ulje origana ispoljilo ulogu
kostabilizatora u formulaciji, uz istovremeno očuvanje njegove veoma visoke antioksidantne aktivnosti
u obliku nanoemulzije, tokom 6 meseci čuvanja.",
publisher = "Association of the Chemical Engineers of Serbia",
journal = "Hemijska industrija",
title = "Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection, Niskoenergetske nanoemulzije kao nosači za etarska ulja u topikalnim formulacijama za antioksidantnu zaštitu kože",
volume = "76",
number = "1",
pages = "29-42",
doi = "10.2298/HEMIND210509004G"
}

Gledović, A., Bajuk-Bogdanović, D., Uskoković-Marković, S., Pavun, L., Savić, S.,& Janošević-Ležaić, A.. (2022). Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection. in Hemijska industrija
Association of the Chemical Engineers of Serbia., 76(1), 29-42.
https://doi.org/10.2298/HEMIND210509004G

Gledović A, Bajuk-Bogdanović D, Uskoković-Marković S, Pavun L, Savić S, Janošević-Ležaić A. Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection. in Hemijska industrija. 2022;76(1):29-42.
doi:10.2298/HEMIND210509004G .

Gledović, Ana, Bajuk-Bogdanović, Danica, Uskoković-Marković, Snežana, Pavun, Leposava, Savić, Snežana, Janošević-Ležaić, Aleksandra, "Low energy nanoemulsions as carriers for essential oils in topical formulations for antioxidant skin protection" in Hemijska industrija, 76, no. 1 (2022):29-42,
https://doi.org/10.2298/HEMIND210509004G . .

TY  - JOUR
AU  - Janošević-Ležaić, Aleksandra
AU  - Bajuk-Bogdanović, Danica
AU  - Krstić, Jugoslav
AU  - Jovanović, Zoran
AU  - Mravik, Željko
AU  - Kovač, Janez
AU  - Gavrilov, Nemanja
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4070
AB  - Transformation of tannic acid (TA), a cheap, abundant and environmentally friendly (by)product, upon carbonization at various temperatures was examined as it is extensively being used in energy storing devices. In addition of reviling what is happening with TA upon carbonization, a step further has been taken to scrutinize the role of carbonized TA (CTA) playing in energy storage composites. Increasing the carbonization temperature from 500 ◦C to 800 ◦C led to a nine orders of magnitude increase in conductivity, from 9⋅10–9 S cm
PB  - Elsevier Ltd
T2  - Fuel
T1  - What role does carbonized tannic acid play in energy storage composites?
VL  - 312
DO  - 10.1016/j.fuel.2021.122930
ER  - 

@article{
author = "Janošević-Ležaić, Aleksandra and Bajuk-Bogdanović, Danica and Krstić, Jugoslav and Jovanović, Zoran and Mravik, Željko and Kovač, Janez and Gavrilov, Nemanja",
year = "2022",
abstract = "Transformation of tannic acid (TA), a cheap, abundant and environmentally friendly (by)product, upon carbonization at various temperatures was examined as it is extensively being used in energy storing devices. In addition of reviling what is happening with TA upon carbonization, a step further has been taken to scrutinize the role of carbonized TA (CTA) playing in energy storage composites. Increasing the carbonization temperature from 500 ◦C to 800 ◦C led to a nine orders of magnitude increase in conductivity, from 9⋅10–9 S cm",
publisher = "Elsevier Ltd",
journal = "Fuel",
title = "What role does carbonized tannic acid play in energy storage composites?",
volume = "312",
doi = "10.1016/j.fuel.2021.122930"
}

Janošević-Ležaić, A., Bajuk-Bogdanović, D., Krstić, J., Jovanović, Z., Mravik, Ž., Kovač, J.,& Gavrilov, N.. (2022). What role does carbonized tannic acid play in energy storage composites?. in Fuel
Elsevier Ltd., 312.
https://doi.org/10.1016/j.fuel.2021.122930

Janošević-Ležaić A, Bajuk-Bogdanović D, Krstić J, Jovanović Z, Mravik Ž, Kovač J, Gavrilov N. What role does carbonized tannic acid play in energy storage composites?. in Fuel. 2022;312.
doi:10.1016/j.fuel.2021.122930 .

Janošević-Ležaić, Aleksandra, Bajuk-Bogdanović, Danica, Krstić, Jugoslav, Jovanović, Zoran, Mravik, Željko, Kovač, Janez, Gavrilov, Nemanja, "What role does carbonized tannic acid play in energy storage composites?" in Fuel, 312 (2022),
https://doi.org/10.1016/j.fuel.2021.122930 . .

TY  - JOUR
AU  - Rupar, Jelena
AU  - Bajuk-Bogdanović, Danica
AU  - Milojević-Rakić, Maja
AU  - Krstić, Jugoslav
AU  - Upadhyay, Kush
AU  - Gavrilov, Nemanja
AU  - Janošević-Ležaić, Aleksandra
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4069
AB  - Here, we propose a novel, electrochemical preparation of in situ N-doped alginate-based carbon precursors with monodispersed zinc ions. Obtained carbons were evaluated by spectroscopic (FTIR, Raman and XPS), textural (N2 physisorption), microscopic (TEM) and elemental (SEM-EDS) descriptors to establish their distinctive fea- tures originating from different synthetic procedures. Carbons characteristics were assessed in view of several carbonization temperatures applied for their preparation from alginate precursors, and individual and joint effect of zinc and nitrogen on the precursor. Obtained Zn monodispersion, emphasizes the significance of electro- chemical preparation, allowing increasing temperature to induce changes from its ionic form to carbonate and oxide, while at 800 ◦C ZnO further reduces and evaporates. Since homogeneously dispersed Zn species acts as porosity evolving agent during carbonization, a substantial surface area is developed, in the range 718–1056 m2 g
PB  - Elsevier B.V.
T2  - Microporous and Mesoporous Materials
T1  - Tailored porosity development in carbons via Zn2+ monodispersion: Fitting supercapacitors
VL  - 335
DO  - 10.1016/j.micromeso.2022.111790
ER  - 

@article{
author = "Rupar, Jelena and Bajuk-Bogdanović, Danica and Milojević-Rakić, Maja and Krstić, Jugoslav and Upadhyay, Kush and Gavrilov, Nemanja and Janošević-Ležaić, Aleksandra",
year = "2022",
abstract = "Here, we propose a novel, electrochemical preparation of in situ N-doped alginate-based carbon precursors with monodispersed zinc ions. Obtained carbons were evaluated by spectroscopic (FTIR, Raman and XPS), textural (N2 physisorption), microscopic (TEM) and elemental (SEM-EDS) descriptors to establish their distinctive fea- tures originating from different synthetic procedures. Carbons characteristics were assessed in view of several carbonization temperatures applied for their preparation from alginate precursors, and individual and joint effect of zinc and nitrogen on the precursor. Obtained Zn monodispersion, emphasizes the significance of electro- chemical preparation, allowing increasing temperature to induce changes from its ionic form to carbonate and oxide, while at 800 ◦C ZnO further reduces and evaporates. Since homogeneously dispersed Zn species acts as porosity evolving agent during carbonization, a substantial surface area is developed, in the range 718–1056 m2 g",
publisher = "Elsevier B.V.",
journal = "Microporous and Mesoporous Materials",
title = "Tailored porosity development in carbons via Zn2+ monodispersion: Fitting supercapacitors",
volume = "335",
doi = "10.1016/j.micromeso.2022.111790"
}

Rupar, J., Bajuk-Bogdanović, D., Milojević-Rakić, M., Krstić, J., Upadhyay, K., Gavrilov, N.,& Janošević-Ležaić, A.. (2022). Tailored porosity development in carbons via Zn2+ monodispersion: Fitting supercapacitors. in Microporous and Mesoporous Materials
Elsevier B.V.., 335.
https://doi.org/10.1016/j.micromeso.2022.111790

Rupar J, Bajuk-Bogdanović D, Milojević-Rakić M, Krstić J, Upadhyay K, Gavrilov N, Janošević-Ležaić A. Tailored porosity development in carbons via Zn2+ monodispersion: Fitting supercapacitors. in Microporous and Mesoporous Materials. 2022;335.
doi:10.1016/j.micromeso.2022.111790 .

Rupar, Jelena, Bajuk-Bogdanović, Danica, Milojević-Rakić, Maja, Krstić, Jugoslav, Upadhyay, Kush, Gavrilov, Nemanja, Janošević-Ležaić, Aleksandra, "Tailored porosity development in carbons via Zn2+ monodispersion: Fitting supercapacitors" in Microporous and Mesoporous Materials, 335 (2022),
https://doi.org/10.1016/j.micromeso.2022.111790 . .

TY  - JOUR
AU  - Janošević-Ležaić, Aleksandra
AU  - Pašti, Igor
AU  - Gledović, Ana
AU  - Antić-Stanković, Jelena
AU  - Božić, Dragana
AU  - Uskoković-Marković, Snežana
AU  - Ćirić-Marjanović, Gordana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4067
AB  - Novel electroactive PANI-GA micro/nanostructured functional copolymers/co-oligomers were synthesized by the oxidative copolymerization of aniline and gallic acid (GA) in an aqueous solution, using ammonium peroxydisulfate (APS) as an oxidant and different initial mole ratios of GA to aniline ([GA]/[aniline]=0.1, 0.25, 0.5 and 1.0). It was found that the yield, molecular structure, morphology, electrical conductivity, electrochemical behavior, antioxidant and antimicrobial properties of PANI-GA strongly depend on [GA]/[aniline] ratio. The highest conductivity (3.8 × 10–3 S cm􀀀 1) showed PANI-GA with dominant polyaniline (PANI) emeraldine salt segments and nanorod morphology, synthesized at [GA]/[aniline] = 0.1. FTIR spectroscopy confirmed the presence of covalently bonded GA and PANI-type structural segments in PANI-GA. The antioxidant activity of PANI-GA was explored by the spectrophotometric 2,2′ -azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assay and electrochemical test for superoxide anion radical, •O2􀀀 . All protonated PANI-GA showed good scavenging activity toward ABTS•+ and •O2􀀀 radicals, whereby the highest activity exhibited PANI-GA produced at [GA]/[aniline] = 1. The radical scavenging activity of protonated PANI-GA samples toward ABTS•+ was much higher than that of PANI. The antimicrobial properties of the PANI-GA against bacteria S. aureus and E. coli, as well as against fungus C. albicans were evaluated. All synthesized protonated PANI-GA were more effective as S. aureus growth inhibitors than pristine GA and PANI. Highest effectiveness against E. coli and C. albicans, higher than that of pristine GA and PANI, showed conductive PANI-GA synthesized at [GA]/[aniline]= 0.1. Based on the obtained experimental results the mechanism of GA and aniline oxidative copolymerization is proposed.
PB  - Elsevier Ltd
T2  - Synthetic Metals
T1  - Copolymerization of aniline and gallic acid: Novel electroactive materials with antioxidant and antimicrobial activities
VL  - 286
DO  - 10.1016/j.synthmet.2022.117048
ER  - 

@article{
author = "Janošević-Ležaić, Aleksandra and Pašti, Igor and Gledović, Ana and Antić-Stanković, Jelena and Božić, Dragana and Uskoković-Marković, Snežana and Ćirić-Marjanović, Gordana",
year = "2022",
abstract = "Novel electroactive PANI-GA micro/nanostructured functional copolymers/co-oligomers were synthesized by the oxidative copolymerization of aniline and gallic acid (GA) in an aqueous solution, using ammonium peroxydisulfate (APS) as an oxidant and different initial mole ratios of GA to aniline ([GA]/[aniline]=0.1, 0.25, 0.5 and 1.0). It was found that the yield, molecular structure, morphology, electrical conductivity, electrochemical behavior, antioxidant and antimicrobial properties of PANI-GA strongly depend on [GA]/[aniline] ratio. The highest conductivity (3.8 × 10–3 S cm􀀀 1) showed PANI-GA with dominant polyaniline (PANI) emeraldine salt segments and nanorod morphology, synthesized at [GA]/[aniline] = 0.1. FTIR spectroscopy confirmed the presence of covalently bonded GA and PANI-type structural segments in PANI-GA. The antioxidant activity of PANI-GA was explored by the spectrophotometric 2,2′ -azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) assay and electrochemical test for superoxide anion radical, •O2􀀀 . All protonated PANI-GA showed good scavenging activity toward ABTS•+ and •O2􀀀 radicals, whereby the highest activity exhibited PANI-GA produced at [GA]/[aniline] = 1. The radical scavenging activity of protonated PANI-GA samples toward ABTS•+ was much higher than that of PANI. The antimicrobial properties of the PANI-GA against bacteria S. aureus and E. coli, as well as against fungus C. albicans were evaluated. All synthesized protonated PANI-GA were more effective as S. aureus growth inhibitors than pristine GA and PANI. Highest effectiveness against E. coli and C. albicans, higher than that of pristine GA and PANI, showed conductive PANI-GA synthesized at [GA]/[aniline]= 0.1. Based on the obtained experimental results the mechanism of GA and aniline oxidative copolymerization is proposed.",
publisher = "Elsevier Ltd",
journal = "Synthetic Metals",
title = "Copolymerization of aniline and gallic acid: Novel electroactive materials with antioxidant and antimicrobial activities",
volume = "286",
doi = "10.1016/j.synthmet.2022.117048"
}

Janošević-Ležaić, A., Pašti, I., Gledović, A., Antić-Stanković, J., Božić, D., Uskoković-Marković, S.,& Ćirić-Marjanović, G.. (2022). Copolymerization of aniline and gallic acid: Novel electroactive materials with antioxidant and antimicrobial activities. in Synthetic Metals
Elsevier Ltd., 286.
https://doi.org/10.1016/j.synthmet.2022.117048

Janošević-Ležaić A, Pašti I, Gledović A, Antić-Stanković J, Božić D, Uskoković-Marković S, Ćirić-Marjanović G. Copolymerization of aniline and gallic acid: Novel electroactive materials with antioxidant and antimicrobial activities. in Synthetic Metals. 2022;286.
doi:10.1016/j.synthmet.2022.117048 .

Janošević-Ležaić, Aleksandra, Pašti, Igor, Gledović, Ana, Antić-Stanković, Jelena, Božić, Dragana, Uskoković-Marković, Snežana, Ćirić-Marjanović, Gordana, "Copolymerization of aniline and gallic acid: Novel electroactive materials with antioxidant and antimicrobial activities" in Synthetic Metals, 286 (2022),
https://doi.org/10.1016/j.synthmet.2022.117048 . .

TY  - JOUR
AU  - Milojević-Rakić, Maja
AU  - Popadić, Daliborka
AU  - Janošević-Ležaić, Aleksandra
AU  - Jevremović, Anka
AU  - Nedić-Vasiljević, Bojana
AU  - Uskoković-Marković, Snežana
AU  - Bajuk-Bogdanović, Danica
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4062
AB  - Ecotoxicity caused by neonicotinoid pesticides is largely due to oxidative stress on non-target species. Due to the fact that reactive radical species reach the environment, materials intended for pesticide removal should be applicable for the simultaneous removal of reactive radicals, as well. This work uses the spectroscopic, adsorptive and antioxidant responses from MFI, FAU and BEA zeolites as descriptors of their potential environmental importance. Different network structures and Si/Al ratios were correlated with excellent zeolite adsorption properties, as over 200 mg g1 of investigated neonicotinoids, acetamiprid and imidacloprid, was achieved in one cycle. Additionally, after two regeneration steps, over 450 mg g1 adsorbed pesticides were retained, in three adsorption cycles. Overall the best results were detected for the FAU zeotype in both tested applications, insecticide adsorption and radical-scavenging performance, with and without insecticides present. The proposed mechanism for adsorption relies on kinetic investigation, isotherm modelling and spectroscopic post-adsorption analysis and targets zeolite hydroxyl/siloxane groups as active sites for insecticide adsorption via hydrogen bonding. Neat, welldefined zeolite structures enable their prospective application in ecotoxic species removal.
PB  - The Royal Society of Chemistry
T2  - Environmental science. Processes & impacts
T1  - MFI, BEA and FAU zeolite scavenging role in neonicotinoids and radical species elimination
VL  - 24
IS  - 2
SP  - 265
EP  - 276
DO  - 10.1039/d1em00437a
ER  - 

@article{
author = "Milojević-Rakić, Maja and Popadić, Daliborka and Janošević-Ležaić, Aleksandra and Jevremović, Anka and Nedić-Vasiljević, Bojana and Uskoković-Marković, Snežana and Bajuk-Bogdanović, Danica",
year = "2022",
abstract = "Ecotoxicity caused by neonicotinoid pesticides is largely due to oxidative stress on non-target species. Due to the fact that reactive radical species reach the environment, materials intended for pesticide removal should be applicable for the simultaneous removal of reactive radicals, as well. This work uses the spectroscopic, adsorptive and antioxidant responses from MFI, FAU and BEA zeolites as descriptors of their potential environmental importance. Different network structures and Si/Al ratios were correlated with excellent zeolite adsorption properties, as over 200 mg g1 of investigated neonicotinoids, acetamiprid and imidacloprid, was achieved in one cycle. Additionally, after two regeneration steps, over 450 mg g1 adsorbed pesticides were retained, in three adsorption cycles. Overall the best results were detected for the FAU zeotype in both tested applications, insecticide adsorption and radical-scavenging performance, with and without insecticides present. The proposed mechanism for adsorption relies on kinetic investigation, isotherm modelling and spectroscopic post-adsorption analysis and targets zeolite hydroxyl/siloxane groups as active sites for insecticide adsorption via hydrogen bonding. Neat, welldefined zeolite structures enable their prospective application in ecotoxic species removal.",
publisher = "The Royal Society of Chemistry",
journal = "Environmental science. Processes & impacts",
title = "MFI, BEA and FAU zeolite scavenging role in neonicotinoids and radical species elimination",
volume = "24",
number = "2",
pages = "265-276",
doi = "10.1039/d1em00437a"
}

Milojević-Rakić, M., Popadić, D., Janošević-Ležaić, A., Jevremović, A., Nedić-Vasiljević, B., Uskoković-Marković, S.,& Bajuk-Bogdanović, D.. (2022). MFI, BEA and FAU zeolite scavenging role in neonicotinoids and radical species elimination. in Environmental science. Processes & impacts
The Royal Society of Chemistry., 24(2), 265-276.
https://doi.org/10.1039/d1em00437a

Milojević-Rakić M, Popadić D, Janošević-Ležaić A, Jevremović A, Nedić-Vasiljević B, Uskoković-Marković S, Bajuk-Bogdanović D. MFI, BEA and FAU zeolite scavenging role in neonicotinoids and radical species elimination. in Environmental science. Processes & impacts. 2022;24(2):265-276.
doi:10.1039/d1em00437a .

Milojević-Rakić, Maja, Popadić, Daliborka, Janošević-Ležaić, Aleksandra, Jevremović, Anka, Nedić-Vasiljević, Bojana, Uskoković-Marković, Snežana, Bajuk-Bogdanović, Danica, "MFI, BEA and FAU zeolite scavenging role in neonicotinoids and radical species elimination" in Environmental science. Processes & impacts, 24, no. 2 (2022):265-276,
https://doi.org/10.1039/d1em00437a . .

TY  - CONF
AU  - Gledović, Ana
AU  - Bajuk-Bogdanović, Danica
AU  - Uskoković-Marković, Snežana
AU  - Pavun, Leposava
AU  - Savić, Snežana
AU  - Janošević-Ležaić, Aleksandra
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4673
AB  - Aromatic plants have been used since ancient times as a source of essential oils (EOs)
which are known as natural remedies in traditional medicine systems – phytotherapy and
aromatherapy, but they are also widely used for everyday purposes (for example, as fragrant
components in skincare preparations and perfumery; as flavours and natural preservatives
in food industry). It is known that many EOs contain molecules with considerable
antioxidant activity, such as phenolic compounds, flavonoids and terpenoids, acting alone or
synergistically. Besides antimicrobial action, EOs prepared from plants form the Lamiaceae
family, such as basil −BA (Ocimum basilicum), oregano – OR (Origanum vulgare) and lemon
balm − LB (Melissa officinalis) leaves are reported to scavenge free radicals (1). Therefore,
these particular EOs and their bioactives could be good candidates for skin-protective
formulations. Nanoemulsions (NEs), especially those produced by low energy methods, are
recently proposed as prospective carriers for sensitive and natural ingredients such as EOs,
in order to ensure their stabilization. Additionally, some EOs can act as cosurfactants and
promote low energy nanoemulsification. Having in mind that EOs cannot be used undiluted,
oil-in-water NEs could be an appropriate delivery system, representing fluid formulations
with ultra-fine droplets, pleasant visual appearance, and improved stability compared to
classic macroemulsions (2). Firstly, NEs were prepared different EOs (BA, OR or LB) with
polyethylene glycol free (PEG-free) natural surfactants/emollients mixture (containing
polyglycerol-4 laurate as the main surfactant) suitable for cold processing via the Phase
inversion composition (PIC) method. NEs physicochemical stability was confirmed by
particle size distribution analysis, electrical conductivity and pH value measurements, as
well as by optical microscopy observations. The type of EO and the concentration of
surfactants/emollient mixture were proven to be crucial factors governing NE properties
and stability. Raman spectra of EOs verified their main active ingredients and detected
possible interactions with the nanocarrier (3). The antioxidant activity towards the DPPH
radical in methanol was concentration-dependent with a similar trend for neat oils and oil-
loaded NEs (OR> LB> BA). However, the ABTS test in an aqueous medium revealed notable
change in the order of activity with increased EO concentration and after EO nanonisation.
Overall, the highest antioxidant activity was observed for OR and OR-loaded NE (> 95%
INH ABTS and > 85% INH DPPH), implying at some optimal package of OR within the nanocarrier
which preserved its high antioxidant performance and ensured its stability during 6 months
of storage.
AB  - Aromatične biljke koriste se od davnina za dobijanje etarskih ulja (EOs) koja su
poznata kao prirodni lekovi u tradicionalnim sistemima lečenja – fitoterapiji i aromaterapiji,
a takođe je široko rasprostranjena njihova upotreba u svakodnevnom životu (na primer, kao
mirisne komponente u kozmetičkim proizvodima i parfemima; kao korigensi ukusa i
prirodni konzervansi u prehrambenoj industriji). Brojna EOs sadrže molekule kao što su
fenolna jedinjenja, flavonoidi i terpenoidi koji ispoljavaju značajnu antioksidativnu aktivnost,
delujući samostalno ili sinergistički. Pored antimikrobnog dejstva, EOs dobijena iz listova
biljaka familije Lamiaceae, kao što je bosiljak - BA (Ocimum basilicum), origano – OR
(Origanum vulgare) i matičnjak − LB (Melissa officinalis) deluju kao hvatači slobodnih
radikala (1). Prema tome, pomenuta EOs i njihovi bioaktivni sastojci mogu biti dobri
kandidati za razvoj formulacija za zaštitu kože. Nanoemulzije (NEs), posebno one
proizvedene niskoenergetskim metodama, odnedavno se predlažu kao prospektivni nosači
za prirodne i osetljive sastojke poput EOs, sa ciljem da se obezbedi njihova stabilizacija.
Dodatno, neka EOs imaju ulogu kosurfaktanta i pospešuju niskoenergetsku
nanoemulzifikaciju. Imajući u vidu da se EOs ne mogu koristiti nerazblažena, NEs ulje u vodi
tipa mogu biti adekvatni nosači, s obzirom da su u pitanju fluidne formulacije sa ultra-finim
veličinama kapi, prijatnim vizuelnim izgledom, kao i poboljšanom stabilnošću u poređenju sa
klasičnim makroemulzijama (2). Prvo su pripremljene NEs sa različitim EOs (BA, OR ili LB),
sa smešom prirodnim surfaktanata i emolijensa (bez polietilenglikola - PEG, gde je
poligliceril-4 laurat glavni surfaktant) koja je pogodna za izradu na hladno primenom
metode inverzije faza (engl. Phase inversion composition ‐ PIC method). Fizičkohemijska
stabilnost NEs potvrđena je analizom distribucije veličina kapi, merenjem električne
provodljivosti i pH vrednosti, kao i optičkom mikroskopijom. Nađeno je da su vrsta EO i
koncentracija smeše surfaktanata i emolijensa ključni faktori koji utiču na karakteristike i
stabilnost dobijenih NE. Tehnikom Ramanske spektroskopije potvrđeni su glavni aktivni
sastojci etarskih ulja i detektovane su moguće interakcije sa nanonosačem. Pokazano je da je
antioksidativna aktivnost prema DPPH radikalu u metanolu koncentraciono zavisna, sa
sličnim trendom za čista etarska ulja i za NEs sa uljima (OR> LB> BA). Međutim, ABTS test u
vodenoj sredini pokazao je izrazite promene u redosledu aktivnosti sa povećanjem
koncentracije EO i nakon nanonizacije EO. Generalno, najjača aktioksidativna aktivnost
primećena je u slučaju OR i OR-NE (> 95% INH ABTS i > 85% INH DPPH), što ukazuje na
optimalno pakovanje OR unutar nanonosača čime su očuvane njegove antioksidativne
performanse i obezbeđena stabilnost tokom 6 meseci čuvanja.
PB  - Savez farmaceutskih udruženja Srbije (SFUS)
C3  - Arhiv za farmaciju
T1  - Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection
T1  - Niskoenergetske nanoemulzije kao potencijalni nosači za etarska ulja u formulacijama za antioksidativnu zaštitu kože
VL  - 71
IS  - 5 suplement
SP  - S96
EP  - S99
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4673
ER  - 

@conference{
author = "Gledović, Ana and Bajuk-Bogdanović, Danica and Uskoković-Marković, Snežana and Pavun, Leposava and Savić, Snežana and Janošević-Ležaić, Aleksandra",
year = "2021",
abstract = "Aromatic plants have been used since ancient times as a source of essential oils (EOs)
which are known as natural remedies in traditional medicine systems – phytotherapy and
aromatherapy, but they are also widely used for everyday purposes (for example, as fragrant
components in skincare preparations and perfumery; as flavours and natural preservatives
in food industry). It is known that many EOs contain molecules with considerable
antioxidant activity, such as phenolic compounds, flavonoids and terpenoids, acting alone or
synergistically. Besides antimicrobial action, EOs prepared from plants form the Lamiaceae
family, such as basil −BA (Ocimum basilicum), oregano – OR (Origanum vulgare) and lemon
balm − LB (Melissa officinalis) leaves are reported to scavenge free radicals (1). Therefore,
these particular EOs and their bioactives could be good candidates for skin-protective
formulations. Nanoemulsions (NEs), especially those produced by low energy methods, are
recently proposed as prospective carriers for sensitive and natural ingredients such as EOs,
in order to ensure their stabilization. Additionally, some EOs can act as cosurfactants and
promote low energy nanoemulsification. Having in mind that EOs cannot be used undiluted,
oil-in-water NEs could be an appropriate delivery system, representing fluid formulations
with ultra-fine droplets, pleasant visual appearance, and improved stability compared to
classic macroemulsions (2). Firstly, NEs were prepared different EOs (BA, OR or LB) with
polyethylene glycol free (PEG-free) natural surfactants/emollients mixture (containing
polyglycerol-4 laurate as the main surfactant) suitable for cold processing via the Phase
inversion composition (PIC) method. NEs physicochemical stability was confirmed by
particle size distribution analysis, electrical conductivity and pH value measurements, as
well as by optical microscopy observations. The type of EO and the concentration of
surfactants/emollient mixture were proven to be crucial factors governing NE properties
and stability. Raman spectra of EOs verified their main active ingredients and detected
possible interactions with the nanocarrier (3). The antioxidant activity towards the DPPH
radical in methanol was concentration-dependent with a similar trend for neat oils and oil-
loaded NEs (OR> LB> BA). However, the ABTS test in an aqueous medium revealed notable
change in the order of activity with increased EO concentration and after EO nanonisation.
Overall, the highest antioxidant activity was observed for OR and OR-loaded NE (> 95%
INH ABTS and > 85% INH DPPH), implying at some optimal package of OR within the nanocarrier
which preserved its high antioxidant performance and ensured its stability during 6 months
of storage., Aromatične biljke koriste se od davnina za dobijanje etarskih ulja (EOs) koja su
poznata kao prirodni lekovi u tradicionalnim sistemima lečenja – fitoterapiji i aromaterapiji,
a takođe je široko rasprostranjena njihova upotreba u svakodnevnom životu (na primer, kao
mirisne komponente u kozmetičkim proizvodima i parfemima; kao korigensi ukusa i
prirodni konzervansi u prehrambenoj industriji). Brojna EOs sadrže molekule kao što su
fenolna jedinjenja, flavonoidi i terpenoidi koji ispoljavaju značajnu antioksidativnu aktivnost,
delujući samostalno ili sinergistički. Pored antimikrobnog dejstva, EOs dobijena iz listova
biljaka familije Lamiaceae, kao što je bosiljak - BA (Ocimum basilicum), origano – OR
(Origanum vulgare) i matičnjak − LB (Melissa officinalis) deluju kao hvatači slobodnih
radikala (1). Prema tome, pomenuta EOs i njihovi bioaktivni sastojci mogu biti dobri
kandidati za razvoj formulacija za zaštitu kože. Nanoemulzije (NEs), posebno one
proizvedene niskoenergetskim metodama, odnedavno se predlažu kao prospektivni nosači
za prirodne i osetljive sastojke poput EOs, sa ciljem da se obezbedi njihova stabilizacija.
Dodatno, neka EOs imaju ulogu kosurfaktanta i pospešuju niskoenergetsku
nanoemulzifikaciju. Imajući u vidu da se EOs ne mogu koristiti nerazblažena, NEs ulje u vodi
tipa mogu biti adekvatni nosači, s obzirom da su u pitanju fluidne formulacije sa ultra-finim
veličinama kapi, prijatnim vizuelnim izgledom, kao i poboljšanom stabilnošću u poređenju sa
klasičnim makroemulzijama (2). Prvo su pripremljene NEs sa različitim EOs (BA, OR ili LB),
sa smešom prirodnim surfaktanata i emolijensa (bez polietilenglikola - PEG, gde je
poligliceril-4 laurat glavni surfaktant) koja je pogodna za izradu na hladno primenom
metode inverzije faza (engl. Phase inversion composition ‐ PIC method). Fizičkohemijska
stabilnost NEs potvrđena je analizom distribucije veličina kapi, merenjem električne
provodljivosti i pH vrednosti, kao i optičkom mikroskopijom. Nađeno je da su vrsta EO i
koncentracija smeše surfaktanata i emolijensa ključni faktori koji utiču na karakteristike i
stabilnost dobijenih NE. Tehnikom Ramanske spektroskopije potvrđeni su glavni aktivni
sastojci etarskih ulja i detektovane su moguće interakcije sa nanonosačem. Pokazano je da je
antioksidativna aktivnost prema DPPH radikalu u metanolu koncentraciono zavisna, sa
sličnim trendom za čista etarska ulja i za NEs sa uljima (OR> LB> BA). Međutim, ABTS test u
vodenoj sredini pokazao je izrazite promene u redosledu aktivnosti sa povećanjem
koncentracije EO i nakon nanonizacije EO. Generalno, najjača aktioksidativna aktivnost
primećena je u slučaju OR i OR-NE (> 95% INH ABTS i > 85% INH DPPH), što ukazuje na
optimalno pakovanje OR unutar nanonosača čime su očuvane njegove antioksidativne
performanse i obezbeđena stabilnost tokom 6 meseci čuvanja.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection, Niskoenergetske nanoemulzije kao potencijalni nosači za etarska ulja u formulacijama za antioksidativnu zaštitu kože",
volume = "71",
number = "5 suplement",
pages = "S96-S99",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4673"
}

Gledović, A., Bajuk-Bogdanović, D., Uskoković-Marković, S., Pavun, L., Savić, S.,& Janošević-Ležaić, A.. (2021). Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije (SFUS)., 71(5 suplement), S96-S99.
https://hdl.handle.net/21.15107/rcub_farfar_4673

Gledović A, Bajuk-Bogdanović D, Uskoković-Marković S, Pavun L, Savić S, Janošević-Ležaić A. Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection. in Arhiv za farmaciju. 2021;71(5 suplement):S96-S99.
https://hdl.handle.net/21.15107/rcub_farfar_4673 .

Gledović, Ana, Bajuk-Bogdanović, Danica, Uskoković-Marković, Snežana, Pavun, Leposava, Savić, Snežana, Janošević-Ležaić, Aleksandra, "Low energy nanoemulsions as potential carriers for essential oils in formulations for antioxidant skin protection" in Arhiv za farmaciju, 71, no. 5 suplement (2021):S96-S99,
https://hdl.handle.net/21.15107/rcub_farfar_4673 .

TY  - JOUR
AU  - Janošević-Ležaić, Aleksandra
AU  - Pejić, Nataša
AU  - Goronja, Jelena
AU  - Pavun, Leposava
AU  - Ðikanović, Danijela
AU  - Malenović, Anđelija
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4056
AB  - The effect of acetonitrile (ACN) on the micellization of a cationic surfactant, cetyltrimethylammo-nium bromide (CTAB), in aqueous solutions at different temperatures was studied. The critical micellar concentration (CMC) as well as the degree of counter ion dissociation () of CTAB in aqueous ACN mixtures (1020 % v/v) at various temperatures (291.2298.2 K) were determined by electrical conduc-tivity measurements, while steady-state fluorescence measurements were used to determine several CMCs (for comparison) and a micellar aggregation number (Nagg) as well. At a fixed temperature, both an increase in CMC and a decrease in Nagg were observed for an increase in ACN in the solvent mixture. With a temperature increase, CMC values increased for 10 % (v/v) ACN, while for both 15 % and 20 % (v/v) ACN, CMC values were a minimum at T = 295.2 K with a temperature increase. In addition, some aspects related to the Krafft temperature behavior of CTAB in the examined micellar systems are dis-cussed.
AB  - Беше испитано влијанието на ацетонитрилот (ACN) врз мицелизацијата на катјонски сурфактант, цетилтриметиламониум бромид (CTAB), во водна средина на различни температури. Со помош на мерења на електричната спроводливост, беа определени критичната мицеларна концентрација (CMC), и степенот на дисоцијација на спротивните јони () на CTAB во водни смеси на ACN (1020 % v/v) на различни температури (291,2298,2 K), додека за определување на неколку CMC (за споредба), како и на мицеларен агрегационен број (Nagg) беа употребени рамнотежни флуоресцентни мерења. На фиксна температура беше забележано зголемување на CMC и намалување на Nagg со зголемување на ACN во смесата на растворот. Со зголемување на температурата вредностите на CMC се зголемија за 10 % (v/v) ACN, додека за 15 % и за 20 % (v/v) ACN, вредностите на CMC при зголемување на температурата на T = 295,2 K беа минимални. Покрај тоа, дискутирани се некои аспекти што се поврзани со однесувањето на температурата на Krafft на CTAB во испитуваните мицеларни системи.
PB  - Macedonian Journal of Chemistry and Chemical Engineering
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies
T1  - Мицеларни својства на цетилтриметиламониум бромид во смесата од ацетонитрил вода: кондуктометриски и флуоресцентни студии
VL  - 40
IS  - 2
SP  - 277
EP  - 287
DO  - 10.20450/MJCCE.2021.2394
ER  - 

@article{
author = "Janošević-Ležaić, Aleksandra and Pejić, Nataša and Goronja, Jelena and Pavun, Leposava and Ðikanović, Danijela and Malenović, Anđelija",
year = "2021",
abstract = "The effect of acetonitrile (ACN) on the micellization of a cationic surfactant, cetyltrimethylammo-nium bromide (CTAB), in aqueous solutions at different temperatures was studied. The critical micellar concentration (CMC) as well as the degree of counter ion dissociation () of CTAB in aqueous ACN mixtures (1020 % v/v) at various temperatures (291.2298.2 K) were determined by electrical conduc-tivity measurements, while steady-state fluorescence measurements were used to determine several CMCs (for comparison) and a micellar aggregation number (Nagg) as well. At a fixed temperature, both an increase in CMC and a decrease in Nagg were observed for an increase in ACN in the solvent mixture. With a temperature increase, CMC values increased for 10 % (v/v) ACN, while for both 15 % and 20 % (v/v) ACN, CMC values were a minimum at T = 295.2 K with a temperature increase. In addition, some aspects related to the Krafft temperature behavior of CTAB in the examined micellar systems are dis-cussed., Беше испитано влијанието на ацетонитрилот (ACN) врз мицелизацијата на катјонски сурфактант, цетилтриметиламониум бромид (CTAB), во водна средина на различни температури. Со помош на мерења на електричната спроводливост, беа определени критичната мицеларна концентрација (CMC), и степенот на дисоцијација на спротивните јони () на CTAB во водни смеси на ACN (1020 % v/v) на различни температури (291,2298,2 K), додека за определување на неколку CMC (за споредба), како и на мицеларен агрегационен број (Nagg) беа употребени рамнотежни флуоресцентни мерења. На фиксна температура беше забележано зголемување на CMC и намалување на Nagg со зголемување на ACN во смесата на растворот. Со зголемување на температурата вредностите на CMC се зголемија за 10 % (v/v) ACN, додека за 15 % и за 20 % (v/v) ACN, вредностите на CMC при зголемување на температурата на T = 295,2 K беа минимални. Покрај тоа, дискутирани се некои аспекти што се поврзани со однесувањето на температурата на Krafft на CTAB во испитуваните мицеларни системи.",
publisher = "Macedonian Journal of Chemistry and Chemical Engineering",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies, Мицеларни својства на цетилтриметиламониум бромид во смесата од ацетонитрил вода: кондуктометриски и флуоресцентни студии",
volume = "40",
number = "2",
pages = "277-287",
doi = "10.20450/MJCCE.2021.2394"
}

Janošević-Ležaić, A., Pejić, N., Goronja, J., Pavun, L., Ðikanović, D.,& Malenović, A.. (2021). Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies. in Macedonian Journal of Chemistry and Chemical Engineering
Macedonian Journal of Chemistry and Chemical Engineering., 40(2), 277-287.
https://doi.org/10.20450/MJCCE.2021.2394

Janošević-Ležaić A, Pejić N, Goronja J, Pavun L, Ðikanović D, Malenović A. Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies. in Macedonian Journal of Chemistry and Chemical Engineering. 2021;40(2):277-287.
doi:10.20450/MJCCE.2021.2394 .

Janošević-Ležaić, Aleksandra, Pejić, Nataša, Goronja, Jelena, Pavun, Leposava, Ðikanović, Danijela, Malenović, Anđelija, "Micellar properties of cetyltrimethylammonium bromide in an acetonitrile-water mixture: conductometric and fluorescence studies" in Macedonian Journal of Chemistry and Chemical Engineering, 40, no. 2 (2021):277-287,
https://doi.org/10.20450/MJCCE.2021.2394 . .

TY  - JOUR
AU  - Pavun, Leposava
AU  - Janošević-Ležaić, Aleksandra
AU  - Tanasković, Slađana
AU  - Ušjak, Dušan
AU  - Milenković, Marina
AU  - Uskoković-Marković, Snežana
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4055
AB  - The presence of residual cardiovascular disease (CVD) risk is a current dilemma in clinical practice; indeed, despite optimal management and treatment, a considerable proportion of patients still undergo major CV events. Novel lipoprotein biomarkers are suggested as possible targets for improving the outcomes of patients at higher risk for CVD, and their impact on major CV events and mortality have previously been investigated. Innovative antidiabetic therapies have recently shown a significant reduction in atherogenic lipoproteins, beyond their effects on glucose parameters; it has also been suggested that such anti-atherogenic effect may represent a valuable mechanistic explanation for the cardiovascular benefit of, at least, some of the novel antidiabetic agents, such as glucagon-like peptide-1 receptor agonists. This emphasizes the need for further research in the field in order to clearly assess the effects of innovative treatments on different novel biomarkers, including atherogenic lipoproteins, such as small dense low-density lipoprotein (LDL), lipoprotein(a) (Lp(a)) and dysfunctional high-density lipoprotein (HDL). The current article discusses the clinical importance of novel lipid biomarkers for better management of patients in order to overcome residual cardiovascular risk.
AB  - Постои постојана потреба од ефикасни лекови, комбинации на лекови и методи за спречување на бактериски и вирусни инфекции, вклучувајќи го и коронавирусот. Познато е дека улогата на елементи во траги во зајакнување на човековиот имун систем е значајна. Витамините, микроелементите, вклучувајќи цинк, железо, селен, магнезиум и бакар, масните киселини омега-3 играат значајна физиолошка улога во унапредување на имуниот систем. Цинкот е неопходен микроелемент за основните ензимски физиолошки процеси. Тој игра важна улога во делбата на клетките и е вклучен во развојот на клетки одговорни за неспецифичен имунитет. Познато е дека недостигот на цинк ги предиспонира пациентите на вирусни инфекции поради намалениот антивирусен имунитет. Од друга страна, флавоноидите како метаболити на растенијата играат важна улога во спречување на оксидативен стрес. Овој труд има за цел да ја дискутира in vitro улогата на цинкот, флавонидите и нивните комплекси, како и нивните антиоксидативни и антимикорбни активности. Разгледана е и оправданоста за истовремена употреба на цинк и флавоноиди.
PB  - Macedonian Journal of Chemistry and Chemical Engineering
T2  - Macedonian Journal of Chemistry and Chemical Engineering
T1  - Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?
T1  - Aнтиоксидативен капацитет и антимикробни ефекти на комплекси
на цинк со флавоноиди – дали постои синергизам?
VL  - 40
IS  - 2
SP  - 231
EP  - 239
DO  - 10.20450/mjcce.2021.2401
ER  - 

@article{
author = "Pavun, Leposava and Janošević-Ležaić, Aleksandra and Tanasković, Slađana and Ušjak, Dušan and Milenković, Marina and Uskoković-Marković, Snežana",
year = "2021",
abstract = "The presence of residual cardiovascular disease (CVD) risk is a current dilemma in clinical practice; indeed, despite optimal management and treatment, a considerable proportion of patients still undergo major CV events. Novel lipoprotein biomarkers are suggested as possible targets for improving the outcomes of patients at higher risk for CVD, and their impact on major CV events and mortality have previously been investigated. Innovative antidiabetic therapies have recently shown a significant reduction in atherogenic lipoproteins, beyond their effects on glucose parameters; it has also been suggested that such anti-atherogenic effect may represent a valuable mechanistic explanation for the cardiovascular benefit of, at least, some of the novel antidiabetic agents, such as glucagon-like peptide-1 receptor agonists. This emphasizes the need for further research in the field in order to clearly assess the effects of innovative treatments on different novel biomarkers, including atherogenic lipoproteins, such as small dense low-density lipoprotein (LDL), lipoprotein(a) (Lp(a)) and dysfunctional high-density lipoprotein (HDL). The current article discusses the clinical importance of novel lipid biomarkers for better management of patients in order to overcome residual cardiovascular risk., Постои постојана потреба од ефикасни лекови, комбинации на лекови и методи за спречување на бактериски и вирусни инфекции, вклучувајќи го и коронавирусот. Познато е дека улогата на елементи во траги во зајакнување на човековиот имун систем е значајна. Витамините, микроелементите, вклучувајќи цинк, железо, селен, магнезиум и бакар, масните киселини омега-3 играат значајна физиолошка улога во унапредување на имуниот систем. Цинкот е неопходен микроелемент за основните ензимски физиолошки процеси. Тој игра важна улога во делбата на клетките и е вклучен во развојот на клетки одговорни за неспецифичен имунитет. Познато е дека недостигот на цинк ги предиспонира пациентите на вирусни инфекции поради намалениот антивирусен имунитет. Од друга страна, флавоноидите како метаболити на растенијата играат важна улога во спречување на оксидативен стрес. Овој труд има за цел да ја дискутира in vitro улогата на цинкот, флавонидите и нивните комплекси, како и нивните антиоксидативни и антимикорбни активности. Разгледана е и оправданоста за истовремена употреба на цинк и флавоноиди.",
publisher = "Macedonian Journal of Chemistry and Chemical Engineering",
journal = "Macedonian Journal of Chemistry and Chemical Engineering",
title = "Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?, Aнтиоксидативен капацитет и антимикробни ефекти на комплекси
на цинк со флавоноиди – дали постои синергизам?",
volume = "40",
number = "2",
pages = "231-239",
doi = "10.20450/mjcce.2021.2401"
}

Pavun, L., Janošević-Ležaić, A., Tanasković, S., Ušjak, D., Milenković, M.,& Uskoković-Marković, S.. (2021). Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?. in Macedonian Journal of Chemistry and Chemical Engineering
Macedonian Journal of Chemistry and Chemical Engineering., 40(2), 231-239.
https://doi.org/10.20450/mjcce.2021.2401

Pavun L, Janošević-Ležaić A, Tanasković S, Ušjak D, Milenković M, Uskoković-Marković S. Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?. in Macedonian Journal of Chemistry and Chemical Engineering. 2021;40(2):231-239.
doi:10.20450/mjcce.2021.2401 .

Pavun, Leposava, Janošević-Ležaić, Aleksandra, Tanasković, Slađana, Ušjak, Dušan, Milenković, Marina, Uskoković-Marković, Snežana, "Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist?" in Macedonian Journal of Chemistry and Chemical Engineering, 40, no. 2 (2021):231-239,
https://doi.org/10.20450/mjcce.2021.2401 . .

TY  - JOUR
AU  - Janićijević, Dejana
AU  - Jevremović, Anka
AU  - Janošević-Ležaić, Aleksandra
AU  - Nedić-Vasiljević, Bojana
AU  - Uskoković-Marković, Snežana
AU  - Bajuk-Bogdanović, Danica
AU  - Milojević-Rakić, Maja
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3970
AB  - Composite materials consisting of the silver salt of dodecatungstophosphoric acid and HBEA zeolite are developed in order to give materials of superior adsorption properties for aqueous pesticide removal. Two-step impregnation and an ion-exchange method with variable constituent mass ratios were employed as synthesis procedures. One of the study goals was to optimize the composite preparation for efficient elimination of glyphosate pesticide and to investigate the modulation of antioxidant activity in the presence of pesticide. Based on comprehensive results, we propose mechanisms for simultaneous glyphosate removal and antioxidant activity. Spectroscopic analysis shows that the applied two-step impregnation method results in advanced composite materials with evenly distributed active sites for glyphosate adsorption and radical-scavenging activity. The original Krishnamurti isotherm is successfully used to fit pesticide adsorption data, pointing to co-operative adsorption of glyphosate on partly saturated adsorbents sites. The amount of glyphosate adsorbed from water suspension was 378 mg per gram of composite material, the highest value reported for glyphosate removal to date.
PB  - Elsevier Ltd
T2  - Journal of Environmental Chemical Engineering
T1  - Comparative assessment of pesticide adsorption capacity and antioxidant activity of Silver Dodecatungstophosphate/HΒEA zeolite composites
VL  - 9
IS  - 6
DO  - 10.1016/j.jece.2021.106341
ER  - 

@article{
author = "Janićijević, Dejana and Jevremović, Anka and Janošević-Ležaić, Aleksandra and Nedić-Vasiljević, Bojana and Uskoković-Marković, Snežana and Bajuk-Bogdanović, Danica and Milojević-Rakić, Maja",
year = "2021",
abstract = "Composite materials consisting of the silver salt of dodecatungstophosphoric acid and HBEA zeolite are developed in order to give materials of superior adsorption properties for aqueous pesticide removal. Two-step impregnation and an ion-exchange method with variable constituent mass ratios were employed as synthesis procedures. One of the study goals was to optimize the composite preparation for efficient elimination of glyphosate pesticide and to investigate the modulation of antioxidant activity in the presence of pesticide. Based on comprehensive results, we propose mechanisms for simultaneous glyphosate removal and antioxidant activity. Spectroscopic analysis shows that the applied two-step impregnation method results in advanced composite materials with evenly distributed active sites for glyphosate adsorption and radical-scavenging activity. The original Krishnamurti isotherm is successfully used to fit pesticide adsorption data, pointing to co-operative adsorption of glyphosate on partly saturated adsorbents sites. The amount of glyphosate adsorbed from water suspension was 378 mg per gram of composite material, the highest value reported for glyphosate removal to date.",
publisher = "Elsevier Ltd",
journal = "Journal of Environmental Chemical Engineering",
title = "Comparative assessment of pesticide adsorption capacity and antioxidant activity of Silver Dodecatungstophosphate/HΒEA zeolite composites",
volume = "9",
number = "6",
doi = "10.1016/j.jece.2021.106341"
}

Janićijević, D., Jevremović, A., Janošević-Ležaić, A., Nedić-Vasiljević, B., Uskoković-Marković, S., Bajuk-Bogdanović, D.,& Milojević-Rakić, M.. (2021). Comparative assessment of pesticide adsorption capacity and antioxidant activity of Silver Dodecatungstophosphate/HΒEA zeolite composites. in Journal of Environmental Chemical Engineering
Elsevier Ltd., 9(6).
https://doi.org/10.1016/j.jece.2021.106341

Janićijević D, Jevremović A, Janošević-Ležaić A, Nedić-Vasiljević B, Uskoković-Marković S, Bajuk-Bogdanović D, Milojević-Rakić M. Comparative assessment of pesticide adsorption capacity and antioxidant activity of Silver Dodecatungstophosphate/HΒEA zeolite composites. in Journal of Environmental Chemical Engineering. 2021;9(6).
doi:10.1016/j.jece.2021.106341 .

Janićijević, Dejana, Jevremović, Anka, Janošević-Ležaić, Aleksandra, Nedić-Vasiljević, Bojana, Uskoković-Marković, Snežana, Bajuk-Bogdanović, Danica, Milojević-Rakić, Maja, "Comparative assessment of pesticide adsorption capacity and antioxidant activity of Silver Dodecatungstophosphate/HΒEA zeolite composites" in Journal of Environmental Chemical Engineering, 9, no. 6 (2021),
https://doi.org/10.1016/j.jece.2021.106341 . .