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Overweight and Obesity in Polycystic Ovary Syndrome: Association with Inflammation, Oxidative Stress and Dyslipidemia
(Cambridge University Press, 2022)
Objective: Polycystic ovary syndrome (PCOS) is associated with altered lipid profile and increased small, dense LDL particles (sdLDL). Considering that paraoxonase 1 (PON1) is an anti-oxidative enzyme located on high-density ...
Human health risk assessment of lead, cadmium, and mercury co-exposure from agricultural soils in the Tuzla Canton (Bosnia and Herzegovina) / Procjena zdravstvenoga rizika nakon istovremenog izlaganja olovu, kadmiju i živi iz poljoprivrednoga tla s područja Tuzlanskoga kantona (Bosna i Hercegovina)
(Sciendo, 2021)
The aim of this study was to assess the risk of human exposure to lead (Pb), cadmium (Cd), and mercury (Hg) through agricultural soil by considering both uncertainty and variability in key exposure parameters. For this ...
Vortioxetine as an analgesic in preclinical inflammatory pain models: Mechanism of action
(John Wiley and Sons Inc, 2021)
Vortioxetine is a novel atypical antidepressant with multimodal activity that has recently demonstrated efficacy against neuropathic pain. There is no published data about its analgesic properties in models characterized ...
β-Adrenoceptor Blockade Moderates Neuroinflammation in Male and Female EAE Rats and Abrogates Sexual Dimorphisms in the Major Neuroinflammatory Pathways by Being More Efficient in Males
(Springer, 2022)
Our previous studies showed more severe experimental autoimmune encephalomyelitis (EAE) in male compared with female adult rats, and moderating effect of propranolol-induced β-adrenoceptor blockade on EAE in females, the ...
H2FPEF score predicts atherosclerosis presence in patients with systemic connective tissue disease
(Wiley Periodicals, 2021)
Background: Cardiovascular diseases are common cause of morbidity and mortality in patients with systemic connective tissue diseases (SCTD) due to accelerated atherosclerosis which couldn't be explained by traditional risk ...
Pharmacists' role, work practices, and safety measures against COVID-19: A comparative study
(Elsevier B.V., 2021)
Background: The coronavirus disease 2019 (COVID-19) pandemic poses a great challenge to health systems and their most accessible assets-community pharmacies. Pharmacists faced many challenges such as incorporating safety ...
Sex as a confounding factor in the effects of ageing on rat lymph node t cell compartment
(Elsevier Inc., 2020)
The study examined the influence of sex on the alterations occurring with ageing in rat lymph node (LN) T cell compartment. In female and male rats the decrease in LN T cell counts was followed by a shift in CD4+/CD8+ T ...
Mimicking of phase I metabolism reactions of molindone by HLM and photocatalytic methods with the use of UHPLC-MS/MS
(MDPI AG, 2020)
Establishing the metabolism pathway of the drug undergoing the hepatic biotransformation pathway is one of the most important aspects in the preclinical discovery process since the presence of toxic or reactive metabolites ...
The influence of smoking habits on cadmium and lead blood levels in the Serbian adult people
(Springer-Verlag GmbH Germany, part of Springer Nature, 2020)
According to theWorld Health Organization, in 2015, the Serbian population ranked among the highest ones in Europe in terms of smoking habit: 44.3%males and 36.2%females aged 18–64 smoked tobacco. In the last 7 years, 25%of ...
Serum cystatin C levels are associated with triglycerides/high-density lipoprotein cholesterol ratio in adolescent girls ages between 16-19 years old
(Verduci Editore s.r.l, 2020)
OBJECTIVE: The pathophysiological role of cystatin C in cardiometabolic disorders is not completely explored in young population. On the other hand, together with the increase in obesity, dyslipidemia and insulin resistance ...