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Multi-criteria decision making approach for the optimization of atorvastatin and its impurities separation by micellar liquid chromatography / Multikriterijumski pristup optimizaciji metode micelarne tečne hromatografije za analizu atorvastatina i njegovih nečistoća
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
In the current paper, multi-criteria decision making (MCDM) approach was applied to optimize micellar liquid chromatography (MLC) intended for the pharmaceutical analysis of atorvastatin and its impurities, trans-atorvastatin ...
Pharmacokinetic aspects in dosing regimen in paediatrics / Farmakokinetički aspekti doziranja lekova u pedijatriji
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Clinical trials in paediatric patients are limited due to certain practical, ethical and regulatory aspects. Accordingly, after performing pharmacokinetic (PK) and efficacy/safety clinical trials in adults, clinical trials ...
Combined effects of cadmium and decabrominated diphenyl ether on thyroid hormones in rats
(Inst Medical Research & Occupational Health, Zagreb, 2012)
The aim of this study was to see how a mixture of cadmium (Cd) and decabrominated diphenyl ether (BDE209) affect thyroid function, namely thyroid-stimulating hormone (TSH), thyroxin (T4), free thyroxin (FT4), triiodothyronin ...
Euroanalysis XVI-challenges in modern analytical chemistry
(Springer Heidelberg, Heidelberg, 2012)
Oxidative and nitrosative stress: Mediators of diquat neurotoxicity / Oksidativni i nitrozativni stres - medijatori neurotoksičnosti dikvata
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Most commonly observed central nervous system (CNS) effects induced by systemic toxicity of herbicide diquat (DQ) are general depression and lethargy. Generally, it is accepted that DQ exerts its toxicity through the ...
Assessment of mercury intake associated with fish consumption in Serbia / Procena unosa žive kroz konzumaciju ribe u Srbiji
(Institut za higijenu i tehnologiju mesa, Beograd, 2012)
Nutritional benefits of fish can be attributed primarily to the content of high-quality proteins, vitamins, elements and omega-3 polyunsaturated fatty acids. On the other hand, fish and fishery products are susceptible to ...
Imidazoline receptors ligands / Ligandi imidazolinskih receptora
(Savez hemijskih inženjera, Beograd, 2012)
Extensive biochemical and pharmacological studies have determined three different subtypes of imidazoline receptors: I1-imidazoline receptors (I1-IR) - involved in central inhibition of sympathicus that produce hypotensive ...
Determination of morphine, codeine and 6-monoacetylmorphine in saliva of substance-abuse patients using HPLC/MS methods / Određivanje morfina, kodeina i 6-monoacetilmorfina metodom HPLC/MS u salivi heroinskih zavisnika
(Vojnomedicinska akademija - Institut za naučne informacije, Beograd, 2012)
Background/Aim. Saliva represents an alternative specimen for substances abuse determination in toxicology. Hence, the aim of this study was to optimize a method for saliva specimen preparation for heroin metabolites, ...
Purification of biological samples and validation of bioanalytical HPLC methods for analysis of drugs and their metabolites / Priprema biološkog materijala i validacija bioanalitičkih HPLC metoda za ispitivanje lekova i njihovih metabolite
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Purification of biological matrix prior to HPLC analysis has been complex procedure and source of great variability of analytical results. The most used biological matrixes used for analysis are plasma, serum, urine and ...
A PAMPA Assay as Fast Predictive Model of Passive Human Skin Permeability of New Synthesized Corticosteroid C-21 Esters
(MDPI, Basel, 2012)
The permeation properties of twenty newly synthesized alpha-alkoxyalkanoyl and alpha-aryloxyalkanoyl C-21 esters of standard corticosteroids: Fluocinolone acetonide, dexamethasone, triamcinolone acetonide and hydrocortisone ...