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Development of solid lipid microparticles by melt-emulsification/spray-drying processes as carriers for pulmonary drug delivery
(Elsevier B.V., 2021)
The aim of this study was to optimize the parameters of the complex melt-emulsification process coupled with the spray-drying, in order to maintain the balance between solid lipid microparticles (SLMs) powders aerodynamic ...
Double active BEA zeolite/silver tungstophosphates – Antimicrobial effects and pesticide removal
(Elsevier, 2020)
Novel composites of BEA zeolite and silver tungstophosphate were prepared by different procedures: two-step impregnation, ion-exchange, and as physical mixtures with varying component mass ratios. Composites were characterized ...
Quality benchmarking of smartphone laboratory medicine applications: Comparison of laboratory medicine specialists' and non-laboratory medicine professionals' evaluation
(De Gruyter Open Ltd, 2021)
There are many mobile health applications (apps) now available and some that use in some way laboratory medicine data. Among them, patient-oriented are of the lowest content quality. The aim of this study was to compare ...
Evidence of acute phase reaction in asymptomatic dogs naturally infected with Babesia canis
(Elsevier, 2020)
Asymptomatic outdoor dogs can be carriers of Babesia canis, but data describing the development of an acute phase response (APR) are not available. We hypothesised that these dogs have a moderate APR that could be detected ...
Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease
(American Chemical Society, 2020)
Imidazoline I2 receptors (I2-IR), widely distributed in the CNS and altered in patients that suffer from neurodegenerative disorders, are orphans from a structural point of view, and new I2-IR ligands are urgently required ...
Geochronological investigation of the Danube Djerdap Lake sediments (Serbia): sedimentology and inorganic composition
(Springer Nature B.V., 2020)
The objective of this study is geochronological investigation of sedimentological and inorganic composition, in the Danube Djerdap Lake sediments in order to obtain reliable information about former pollution. Eleven samples ...
Eslicarbazepine acetate interacts in a beneficial manner with standard and alternative analgesics to reduce trigeminal nociception
(Springer Nature, 2020)
Rationale: Acute pain states in the trigeminal region (headaches, dental pain) fall into the most prevalent painful conditions. Standard analgesics (paracetamol/NSAIDs) represent the cornerstone of their treatment, whereas ...
Deciphering Imidazoline Off-targets by Fishing in the Class A of GPCR field
(Wiley-VCH Verlag, 2020)
Based on the finding that a central antihypertensive agent with high affinity for I1-type imidazoline receptors – rilmenidine, shows cytotoxic effects on cultured cancer cell lines, it has been suggested that imidazoline ...
Nanocrystal dispersion of DK-I-56–1, a poorly soluble pyrazoloquinolinone positive modulator of α6 GABAA receptors: Formulation approach toward improved in vivo performance
(Elsevier B.V., 2020)
DK-I-56–1 (7‑methoxy‑2-(4‑methoxy‑d3-phenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one), a recently developed deuterated pyrazoloquinolinone, has been recognized as a lead candidate for treatment of various neuropsychiatric ...
Application of nanofat for treatment of traumatic faecal incontinence after sphincteroplasty – A pilot study
(John Wiley and Sons Inc, 2022)
Aim: The aim of this study was to investigate whether the application of nanofat contain-ing stem cells improves continence in women who had previously undergone anal sphinc-teroplasty with unsatisfactory long-term ...