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Chiral ligand-exchange chromatography for diastereo-enantio separation of exametazime
(Pergamon-Elsevier Science Ltd, Oxford, 2003)
The diastereo-enantio separation of isomeric mixtures of exametazime (HM-PAO) by liquid chromatography is described using an achiral sorbent (RP-18). A chiral eluent with the initial complex of Cu(II) and the optically ...
Safe-by-design gelatin-modified zinc oxide nanoparticles
(Springer Science and Business Media B.V., 2021)
We report an innovative low-cost wet precipitation synthesis method for gelatin-modified zinc oxide nanoparticles (GM ZnO NPs) at the inter- face between the gelatin hydrogel and aqueous elec- trolyte. ...
Sucrose ester-based biocompatible microemulsions as vehicles for aceclofenac as a model drug: formulation approach using D-optimal mixture design
(Springer, New York, 2014)
We assessed the functionality of sucrose esters (sucrose laurate, myristate, palmitate, and stearate), relatively innocuous nonionic surfactants, in formulation of biocompatible microemulsions. The putative influence of ...
Deciphering the spatio-temporal expression and stress regulation of Fam107B, the paralog of the resilience-promoting protein DRR1 in the mouse brain
(Elsevier Ltd, 2015)
Understanding the molecular mechanisms that promote stress resilience might open up new therapeutic avenues to prevent stress-related disorders. We recently characterized a stress and glucocorticoid-regulated gene, ...
Preparation of floating polymer-valsartan delivery systems using supercritical CO2
(Springer Science and Business Media B.V., 2021)
This study investigates pharmaceutical polymers (Soluplus®, HPMCAS, and Eudragit® E100) and supercritical CO2-assisted process for preparation of floating valsartan delivery systems. Tested process (at pressure of 30 MPa ...
Functionality of chitosan‐halloysite nanocomposite films for sustained delivery of antibiotics: The effect of chitosan molar mass
(Wiley Periodicals, Inc., 2020)
This study was designed to investigate functionality of tetracycline‐loaded chitosan‐halloysite nanocomposite films, with focus on evaluating the influence of chitosan molar mass on films applicability for sustained local ...
The Effect of Vacuum-Assisted Closure Therapy on Methicillin-Resistant Staphylococcus aureus Wound Biofilms
(Lippincott Williams & Wilkins, Philadelphia, 2018)
Biofilm-associated wound infections are a major global health issue, and methicillin-resistant Staphylococcus aureus (MRSA) is among the greatest therapeutic challenges. Vacuum-assisted closure (VAC) therapy is now being ...
ELLSA based profiling of surface glycosylation in microorganisms reveals that ß-glucan rich yeasts’ surfaces are selectively recognized with recombinant banana lectin
(Springer Nature, 2020)
The surface of microorganisms is covered with polysaccharide structures which are in immediate contact with receptor structures on host’s cells and antibodies. The interaction between microorganisms and their host is ...
Chaotropic chromatography method development for the determination of aripiprazole and its impurities following analytical quality by design principles
(Wiley-VCH Verlag, 2020)
In this paper, development of robust and reliable chaotropic chromatography method for the determination of aripiprazole and its impurities, following Analytical Quality by Design principles is presented. The efficient ...
Relationship between bone resorption, oxidative stress and inflammation in severe COPD exacerbation
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
Background: The natural course of chronic obstructive pulmonary disease (COPD) is complicated by the development of systemic consequences and co-morbidities. Increasing evidence indicates that COPD and osteoporosis are ...