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Computer-aided biopharmaceutical characterization: Gastrointestinal absorption simulation
(Elsevier Inc., 2013)
This chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input ...
Computational fluid dynamics: Applications in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter introduces the concept of computational fluid dynamics (CFD) and its applications in pharmaceutical technology. Basic theoretical explanations on the mathematics of fluid flow and numerical grids are provided. ...
Route, dose and duration of exposure to cadmium-relevance to oxidative stress induction
(Nova Science Publishers, Inc., 2013)
Cadmium (Cd) is a toxic metal currently ranked as seventh (out of 275) on ATSDR priority list of hazardous substances and it is considered as one of the most important occupational and environmental pollutants. This ...
Chemometric methods application in pharmaceutical products processes analysis control
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on chemometrics and chemometric methods for the analysis of multivariate data. Multivariate data analysis is essential for both product and process development and ...
Neural computing in pharmaceutical products and process development
(Elsevier Inc., 2013)
This chapter presents a review of the possible applications of methods based on neural computing in pharmaceutical products and process development. Some of the methods described are used for classification purposes, whereas ...
Computer-aided formulation development
(Elsevier Inc., 2013)
This chapter introduces the concept of formulation development assisted by computer applications. Development and optimization of various types of pharmaceutical emulsions microemulsions, self-microemulsifying systems, and ...
Experimental design application interpretation in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett-Burman design, ...
Ibuprofen delivery: Pharmaceutical nanotechnology approach
(Nova Science Publishers, Inc., 2013)
Ibuprofen is non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of pain and inflammation related with rheumatoid arthritis, osteoarthritis, dysmenorrhea, headaches, muscle pain, common cold, after ...
Abyssomicins: Isolation, properties, and synthesis
(Elsevier B.V., 2013)
The discovery of abyssomicin class of natural products has been the outcome of the search for secondary metabolites possessing inhibitory effect on p-aminobenzoic (pABA) acid biosynthesis, a biosynthetic pathway found in ...
Robustness of liquid chromatographic method: How to achieve it and how to confirm it?
(Nova Science Publishers, Inc., 2013)
The quality of liquid chromatographic methods developed for pharmaceutical applications is strongly dependent on their robustness. The robustness issue requires a studious strategy where many important aspects regarding ...