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Development and Optimization of an HPLC Analysis of Citalopram and Its Four Nonchiral Impurities Using Experimental Design Methodology
(AOAC Int, Gaithersburg, 2012)
In this study, the RP-HPLC method was investigated for the separation of citalopram and its four impurities by use of statistical experimental design. Initially, the influence of different experimental conditions (buffer ...
Tolerance liability of diazepam is dependent on the dose used for protracted treatment
(Polish Acad Sciences Inst Pharmacology, Krakow, 2012)
Background: Behavioral effects of benzodiazepines following repeated exposure vary according to the intrinsic efficacy of the benzodiazepine studied, treatment schedule and the behavioral parameters evaluated. Methods: We ...
Effects of co-existing autoimmune diseases on serum lipids and lipoprotein subclasses profile in paediatric patients with type 1 diabetes mellitus
(Pergamon-Elsevier Science Ltd, Oxford, 2018)
Objective: Paediatric patients with type 1 diabetes mellitus (T1DM) frequently develop other autoimmune disorders; most commonly autoimmune thyroiditis (ATD) and celiac disease (CD). In this study we evaluated whether ...
Synthesis, characterization and antimicrobial activity of copper and zinc-doped hydroxyapatite nanopowders
(Elsevier Science BV, Amsterdam, 2010)
Antimicrobial materials based on hydroxyapatite are potentially attractive in a wide variety of medical applications. The synthesis of copper and zinc-doped hydroxyapatite was done by neutralization method. This method ...
Comparative Analysis of Essential Oils of Six Anthemis Taxa from Serbia and Montenegro
(Wiley-Blackwell, Malden, 2010)
The essential-oil composition of six Anthemis taxa from several populations in Serbia and Montenegro, Anthemis triumfetti (L.) DC., A. tinctoria L.. A. austriaca JACQ., A. ruthenica BIER., A. COMM L., and A. cretica ssp. ...
Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period
(Lippincott Williams & Wilkins, Philadelphia, 2011)
Martinovic, J, Dopsaj, V, Kotur-Stevuljevic, J, Dopsaj, M, Vujovic, A, Stefanovic, A, and Nesic, G. Oxidative stress biomarker monitoring in elite women volleyball athletes during a 6-week training period. J Strength Cond ...
Environmental and Seasonal Impacts on the Chemical Composition of Satureja horvatii Šilić (Lamiaceae) Essential Oils
(Wiley-Blackwell, Malden, 2011)
The chemical composition of the essential oils of Satureja horvatii SILIC from two natural habitats (Mt. Orjen and Mt. Lovcen in Montenegro) and from cultivated plants (Belgrade, Serbia) were characterized. For the latter, ...
Impact of age, weight and concomitant treatment on lamotrigine pharmacokinetics
(Wiley-Blackwell, Hoboken, 2012)
What is known and Objective: Lamotrigine metabolism may be substantially altered with concomitant administration of valproic acid and/or carbamazepine. Such alterations may require the adjustment of lamotrigine dose to ...
Population pharmacokinetics of topiramate in adult patients with epilepsy using nonlinear mixed effects modelling
(Elsevier Science BV, Amsterdam, 2013)
The objective of the study was to develop population pharmacokinetic model of topiramate (TPM) using nonlinear mixed effects modelling approach. Data were collected from 78 adult epileptic patients on mono- or co-therapy ...
Synchronization of the minimal models of bursting neurons coupled by delayed chemical or electrical synapses
(Iop Publishing Ltd, Bristol, 2012)
The minimal two-dimensional model of bursting neuronal dynamics is used to study the influence of time-delay on the properties of synchronization of bursting neurons. Generic properties of bursting and dependence of the ...