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A new simple liquid chromatographic assay for gentamicin in presence of methylparaben and propylparaben
(Akademiai Kiado ZRt., 2023)
Gentamicin sulfate is a potent broad spectrum aminoglycoside antibiotic which is used against Gram- positive and Gram-negative bacteria. A simple, isocratic HPLC method for separation, identification and determination of ...
Neuropharmacokinetics: the secret life of - old and novel - psychopharmacological drugs
(International Association of Physical Chemists, 2023)
Neuro pharmacokinetics: the secret life of - old and novel - psychopharmacological drugs
Miroslav Savić
Department of Pharmacology, Faculty of Pharmacy, University of Belgrade, Serbia
In the 21st century, the pace of ...
Employing machine learning to assess the accuracy of near-infrared spectroscopy of spent dialysate fluid in monitoring the blood concentrations of uremic toxins
(Institut za Bioloska Istrazivanja, 2023)
Hemodialysis (HD) removes nitrogenous waste products from patients’ blood through a semipermeable mem- brane along a concentration gradient. Near-infrared spectroscopy (NIRS) is an underexplored method of monitoring the ...
Docking studies of some pyrazole containing compounds in the cyclooxygenase-2 active site / Doking studije nekih jedinjenja sa pirazolom u aktivnom mestu ciklooksigenaze-2
(Savez farmaceutskih udruženja Srbije (SFUS), 2023)
Whereas nonselective nonsteroidal anti-inflammatory drugs, such as aspirin, ibuprofen and
diclofenac, inhibit both cyclooxygenase-1 and cyclooxigenase-2 enzymes, selective inhibitors
target cyclooxygenase-2, which is ...
Development and validation of a stability- indicating RP-HPLC method for determination of aripiprazole and its degradation products / Razvoj i validacija RP-HPLC metode za praćenje stabilnosti u cilju određivanja sadržaja aripiprazola i njegovih degradacionih proizvoda
(Savez farmaceutskih udruženja Srbije (SFUS), 2023)
The goal of this study was the optimization of chromatographic conditions and validation
of the isocratic RP-HPLC method for monitoring the stability of aripiprazole, identification and
quantitative analysis of aripiprazole ...
Potentially inappropriate prescribing among older patients and associated factors: comparison of two versions of STOPP/START criteria
(Brazilian Journal of Pharmaceutical Sciences, 2023)
The study aimed to estimate and compare the prevalence and type of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) between the STOPP/START original (v1) and updated version (v2) among ...
QSRR Approach: Application to Retention Mechanism in Liquid Chromatography
(IntechOpen, 2023)
One-factor-at-a-time experimentation was used for a long time as gold-standard
optimization for liquid chromatographic (LC) method development. This approach
has two downsides as it requires a needlessly great number of ...
Pros and Cons of Long-Chain Omega-3 Polyunsaturated Fatty Acids in Cardiovascular Health
(Annual Reviews Inc, 2023)
The long-chain omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are found in seafood, supplements, and concentrated pharmaceutical preparations. Prospective cohort studies demonstrate an ...
Dietary antioxidants and health effects: what are their optimal intakes? / Dijetarni antioksidansi i zdravstveni efekti: koliki je optimalan unos?
(Savez farmaceutskih udruženja Srbije, Beograd, 2023)
A well-balanced diet provides many compounds with antioxidant properties, such as
vitamins, minerals, provitamins (e.g., β-carotene), and phytochemicals (e.g., carotenoids,
polyphenols, organosulfur compounds). In addition ...
Oxidative stress-related risk of the multiple sclerosis development / Rizik razvoja multiple skleroze povezan sa oksidativnim stresom
(Beograd : Društvo medicinskih biohemičara Srbije, 2023)
Background: Multiple sclerosis (MS) is characterized by
inflammation, demyelination and axonal degeneration.
Oxidative stress (OS) plays a significant role in the pathogenesis of the disease. The aim of the study was to ...