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Involvement of toxic metals and PCBs mixture in the thyroid and male reproductive toxicity: In silico toxicogenomic data mining
(Elsevier, 2023)
Toxicological research is mostly limited to considering the effects of a single substance, even though the real exposure of people is reflected in their daily exposure to many different chemical substances in low-doses. ...
Correlation of oxidative stress markers and semen parameters with the outcome of in vitro fertilization / Корелација маркера оксидативног стреса и параметара спермограма са исходом вантелесне оплодње
(Serbia Medical Society, 2020)
Introduction/Objective The aim was to assess the effect of oxidative stress parameters on sperm count, motility, and morphology of spermatozoa, and the influence of different semen parameters on the outcome of in vitro ...
The role of toxic metals and metalloids in nrf2 signaling
(MDPI AG, 2021)
Nuclear factor erythroid 2-related factor 2 (Nrf2), an emerging regulator of cellular resis-tance to oxidants, serves as one of the key defensive factors against a range of pathological processessuch as oxidative damage, ...
Paraoxonase 1 low activity and SYNTAX score may predict postoperative complications after coronary artery surgery
(Verduci Editore s.r.l, 2021)
OBJECTIVE: Coronary artery bypass grafting (CABG) seems to present a powerful trigger of oxidative stress (OS) and acute inflammatory response. This study aimed to estimate the effects of off-pump coronary artery bypass ...
Differences in antioxidant potential of chalcones in human serum: In vitro study
(Elsevier Ireland Ltd, 2020)
An imbalance between oxidants and antioxidants in favour of oxidants, potentially leading to damage, is termed oxidative stress. Antioxidants (AO), either enzymatic or non-enzymatic, are the ones that can reduce diverse ...
Endocan and a novel score for dyslipidemia, oxidative stress and inflammation (DOI score) are independently correlated with glycated hemoglobin (HbA1c) in patients with prediabetes and type 2 diabetes
(Termedia Publishing House Ltd., 2020)
Introduction: We aimed to examine serum endocan level and the summary involvement of dyslipidemia, oxidative stress (OS) and inflammation by calculation of its comprehensive score (i.e. Dyslipidemia-Oxy-Inflammation (DOI) ...
Diabetes and colorectal cancer risk: A new look at molecular mechanisms and potential role of novel antidiabetic agents
(MDPI, 2021)
Epidemiological data have demonstrated a significant association between the presence of type 2 diabetes mellitus (T2DM) and the development of colorectal cancer (CRC). Chronic hyperglycemia, insulin resistance, oxidative ...
Beneficial outcomes of omega-6 and omega-3 polyunsaturated fatty acids on human health: An update for 2021
(MDPI AG, 2021)
Oxidative stress and inflammation have been recognized as important contributors to the risk of chronic non-communicable diseases. Polyunsaturated fatty acids (PUFAs) may regulate the antioxidant signaling pathway and ...
Potential applications of NRF2 modulators in cancer therapy
(MDPI, 2020)
The nuclear factor erythroid 2-related factor 2 (NRF2)–Kelch-like ECH-associated protein 1 (KEAP1) regulatory pathway plays an essential role in protecting cells and tissues from oxidative, electrophilic, and xenobiotic ...
Oxidative stress and inflammation parameters-novel biomarkers for idiopathic pulmonary fibrosis
(Verduci Editore s.r.l, 2022)
Objective: The pathophysiological mechanisms of idiopathic pulmonary fibrosis (IPF) are not well elucidated. It is assumed that oxidative stress and inflammation are the key underlying culprits for its onset and progression. ...