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Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population
(John Wiley and Sons Inc, 2022)
Sertraline is a commonly used SSRI antidepressant drug, metabolized by CYP2C19 and CYP2B6, that exhibits a substantial interindividual variation in clinical response, of which only a part can be attributed to known genetic ...
Atherosclerosis Development and Progression: The Role of Atherogenic Small, Dense LDL
(MDPI, 2022)
Atherosclerosis is responsible for large cardiovascular mortality in many countries globally. It has been shown over the last decades that the reduction of atherosclerotic progression is a critical factor for preventing ...
Spatial distribution of multielements including lanthanides in sediments of Iron Gate I Reservoir in the Danube River
(Springer Science and Business Media Deutschland GmbH, 2021)
Recent studies show that lanthanides (Ln) are becoming emerging pollutants due to their wide application in new technologies,but their environmental fate, transport, and possible accumulation are still relatively unknown. ...
The Influences of Climatic and Lithological Factors on Weathering of Sediments in Humid Badland Areas
(Frontiers Media S.A., 2022)
Climate variables including temperature, rainfall intensity, rainfall acidity, and lithological properties are among the most important factors affecting rock weathering. However, the relative contribution of these four ...
Novel leukocyte and thrombocyte indexes in patients with prediabetes and type 2 diabetes mellitus
(Verduci Editore srl, 2022)
OBJECTIVE: To our knowledge, there are no studies that investigated the relationship between diabetes mellitus type 2 (T2D) and some novel indexes, such as monocyte/granulocyte to lymphocyte ratio (M/GLR), derived neutrophil ...
Factorial analysis of N-acetylcysteine and propolis treatment effects on symptoms, life quality and exacerbations in patients with Chronic Obstructive Pulmonary Disease (COPD): a randomized, double-blind, placebo-controlled trial
(Verduci Editore srl, 2022)
OBJECTIVE: Standard treatment for chronic obstructive pulmonary disease (COPD) includes inhalation therapy along with mucoactive drugs. The aim of this study was to assess the efficacy and safety of orally administered ...
Microwave Assisted Esterification of Aryl/Alkyl Acids Catalyzed by N-Fluorobenzenesulfonimide
(MDPI, 2022)
The susceptibility of the carbonyl group towards nucleophilic attack affords the construction of various organic compounds. Thus, investigations of carbonyl activation applying greener methodologies are highly important. ...
Oxidative stress and inflammation parameters-novel biomarkers for idiopathic pulmonary fibrosis
(Verduci Editore s.r.l, 2022)
Objective: The pathophysiological mechanisms of idiopathic pulmonary fibrosis (IPF) are not well elucidated. It is assumed that oxidative stress and inflammation are the key underlying culprits for its onset and progression. ...
A comparison of Myribase and Doublebase gel: Does qualitative similarity of emollient products imply their direct interchangeability in everyday practice?
(Blackwell Publishing Inc, 2020)
Emollients are acknowledged as a part of standard care in therapeutic and prevention protocols as well as a part of everyday skin care routine. When it comes to making a final decision between two emollient products, the ...
Lipoproteins and cholesterol homeostasis in paediatric nephrotic syndrome patients
(Croatian Society of Medical Biochemistry and Laboratory Medicine, 2022)
Introduction The aim of this study was to investigate lipoprotein particle distributions and the likelihood of achieving cholesterol homeostasis in the remission phase of nephrotic syndrome (NS) in paediatric patients. ...