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Optimization of an RP-HPLC method for drug control analysis
(Marcel Dekker Inc, New York, 2003)
Optimization of important conditions for the reversed-phase high-performance liquid chromatographic method was done for the separation of the active ingredients in Marcaine(R) adrenaline injections (bupivacaine hydrochloride ...
Robustness Testing of Microemulsion Liquid Chromatographic Separation of Simvastatin and its Impurities
(Taylor & Francis Inc, Philadelphia, 2009)
Liquid chromatography employing the microemulsion as eluent was applied for the analysis of simvastatin and its six impurities. Previously, the optimized and validated method was tested to prove the method's capability to ...
Monitoring of impurity level of valsartan and hydrochlorothiazide employing an RP-HPLC gradient mode
(Taylor & Francis Inc, Philadelphia, 2007)
The multi-component preparation Co -Diovan (R) is indicated for the hypertension treatment in patients whose blood pressure is not adequately controlled by monotherapy. Its active ingredients are valsartan and hydrochlorothiazide. ...
Determination of Moclobemide and its Metabolites in Human Plasma by SPE-HPLC-UV: Evaluation of Critical Experimental Conditions and QSRR Study
(Taylor & Francis Inc, Philadelphia, 2009)
A SPE-HPLC-UV method for determination of moclobemide and its major metabolites, Ro 12-5637 and Ro 12-8095, in human plasma had been developed previously and its selectivity was evaluated against the most frequently ...
An Experimental Design Approach to Selecting the Optimum HPLC Conditions for the Determination of 2-Arylimidazoline Derivatives
(Taylor & Francis Inc, Philadelphia, 2009)
In order to improve the chromatographic resolution (Rs) with a good analysis time, experimental designs were applied for multivariate optimization of the experimental conditions of an isocratic reversed phase high performance ...