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QSRR Approach: Application to Retention Mechanism in Liquid Chromatography
(IntechOpen, 2023)
One-factor-at-a-time experimentation was used for a long time as gold-standard
optimization for liquid chromatographic (LC) method development. This approach
has two downsides as it requires a needlessly great number of ...
Potentially inappropriate prescribing among older patients and associated factors: comparison of two versions of STOPP/START criteria
(Brazilian Journal of Pharmaceutical Sciences, 2023)
The study aimed to estimate and compare the prevalence and type of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) between the STOPP/START original (v1) and updated version (v2) among ...
Assessment of causes of stress in a pharmacy student population during semester and examination period / Analiza uzroka stresa u populaciji studenata farmacije tokom semestra i ispitnog roka
(Faculty of Medical Sciences University of Kragujevac, 2023)
Stress is one of the most significant factors that can influence the academic
performance of students. To explore the causes of stress in students, the crosssectional
online survey was conducted during semester (in 2019 ...
Goji Berries: Valuable Sources of Nutrients and Bioactive Compounds
(Elsevier, 2023)
Apart from traditional medicine use, the fruit of Lycium barbarum L., known as red goji berry or wolfberry, is recognized and consumed as a functional food. Beyond nutritional properties, goji berry exerts many biological ...
Regio- and Stereoselective, Intramolecular [2+2] Cycloaddition of Allenes, Promoted by Visible Light Photocatalysis
(John Wiley and Sons Inc, 2023)
Enallenylamides have been utilized for the synthesis of heterobicycle[4.2.0]octane derivatives via Ir/hν promoted [2+2] cycloaddition reaction. The reaction specifically targets the distal double bond of the allene moiety, ...
Docking studies of some pyrazole containing compounds in the cyclooxygenase-2 active site / Doking studije nekih jedinjenja sa pirazolom u aktivnom mestu ciklooksigenaze-2
(Savez farmaceutskih udruženja Srbije (SFUS), 2023)
Whereas nonselective nonsteroidal anti-inflammatory drugs, such as aspirin, ibuprofen and
diclofenac, inhibit both cyclooxygenase-1 and cyclooxigenase-2 enzymes, selective inhibitors
target cyclooxygenase-2, which is ...
High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances
(Elsevier B.V., 2023)
Preclinical development of deuterated pyrazoloquinolinone ligands, promising drug candidates for various neuropsychiatric disorders, was hindered by unusually low solubility in water and oils. DK-I-60-3 (7-methoxy-d3- ...
Predicting sulforaphane-induces adverse effects in prostatic cancer patients via in silico investigation
(Elsevier, 2023)
Prostate cancer is a major cause of death in men. Traditional therapies have limited efficacy, leading to the increased interest in phytochemicals like sulforaphane (SFN), found in cruciferous vegetables. ...
Involvement of toxic metals and PCBs mixture in the thyroid and male reproductive toxicity: In silico toxicogenomic data mining
(Elsevier, 2023)
Toxicological research is mostly limited to considering the effects of a single substance, even though the real exposure of people is reflected in their daily exposure to many different chemical substances in low-doses. ...
Advanced QSRR Modeling in β-CD-Modifed RP-HPLC System
(Marcel Dekker Inc., 2023)