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Use of ANN modelling in structure-retention relationships of diuretics in RP-HPLC
(Pergamon-Elsevier Science Ltd, Oxford, 1999)
Structure-retention relationship study, conducted by RP-HPLC, was used to investigate physical chemical parameters related to the RP retention times of amiloride, hydrochlorothiazide and methyldopa in order to predict the ...
Spectrophotometric and electrochemical study of protolytic equilibria of some oximes-acetylcholinesterase reactivators
(Pergamon-Elsevier Science Ltd, Oxford, 1999)
Newly synthesized oximes, mono and bis imidazole derivatives, which promise to be more effective acetylcholinesterase reactivators than standard antidotes used, were investigated by spectrophotometric and electrochemical ...
Coulometric determination of sulphisomidine, sulphamethoxydiazine and sulphamoxole
(Journal of Pharmaceutical and Biomedical Analysis, 1991)
Quantitative analysis of analgoantipyretics in dosage form using planar chromatography
(Pergamon-Elsevier Science Ltd, Oxford, 2001)
In the therapy of pain of weaker genesis, frequently used drugs usually represent a mix of analgoantipyretics of different chemical structures, mostly derivatives of salicylic acid, pyrazolone and p-aminophenol as well as ...
Statistical optimization of a reversed-phase liquid chromatographic method for the analysis of amiloride and hydrochlorothiazide in tablets
(Pergamon-Elsevier Science Ltd, Oxford, 2000)
A method has been developed for the separation of hydrochlorothiazide and amiloride by high-performance liquid chromatographic (HPLC) method on a C-18 column with detection at 280 nm. The optimal conditions of separation ...
Analytical method development supported by DoE-DS approach for enantioseparation of (S,S)- and (R,R)-moxifloxacin
(Elsevier B.V., 2023)
In this paper, method for enantiomeric purity testing of fourth-generation fluoroquinolone, moxifloxacin hydrochloride, was developed and validated. Exceptional enantioselectivity for this assay was achieved using cyclodextrin ...
Predicting liquid chromatography−electrospray ionization/mass spectrometry signal from the structure of model compounds and experimental factors; case study of aripiprazole and its impurities
(Elsevier Inc., 2023)
A priori estimation of analyte response is crucial for the efficient development of liquid chromatography–electrospray ionization/mass spectrometry (LC–ESI/MS) methods, but remains a demanding task given the lack of knowledge ...
Determination of anti-secalin antibodies in sera from coeliac patients by ELISA-based assay
(Elsevier, 1998)
Coeliac disease (CD) is a permanent intolerance
to dietary prolamins (alcohol soluble protein fraction of cereal gluten) from selected cereals (wheat,
rye, barley and oats) resulting in small intestinal
villus atrophy ...