Pretraživanje
Prikaz rezultata 11-20 od 22
Physicochemical/structural investigation of lipid nanoparticles with high lecithin amounts loaded with patent protected pyrazoloquinolinone ligand DK-I-60-3
(13th World meeting on pharmaceutics, biopharmaceutics and pharmaceutical technology, 28-31 March 2022, Rotterdam, Netherlands, 2022)
Lipid nanoparticles are being intensively investigated for
the formulation of the drugs with poor solubility substances
(1). They represent colloid dispersions of the particles with
lipid matrix that is solid at room ...
Estimation of endotoxin level in nanocrystal dispersion of DK-I-56-1 intended for parenteral administration
(NANOGVA Symposium, October 5th - 6th, 2023, Geneva, Switzerland, 2023)
Estimation of endotoxin level in nanocrystal dispersion of DK-I-56-1 intended for parenteral administration
Jelena Mitrović1, Tanja Ilić1, Ivan Jančić2, Biljana Bufan2, Miroslav Savić3, Snežana Savić1
1 Department of ...
Analyzing the impact of the oil phase selection and curcumin presence on the nanoemulsion stabilizing layer using electron paramagnetic resonance spectroscopy
(8. Kongres farmaceuta Srbije; 12.-15. oktobar, Beograd, Srbija, 2022)
ANALYZING THE IMPACT OF THE OIL PHASE SELECTION AND CURCUMIN
PRESENCE ON THE NANOEMULSION STABILIZING LAYER USING ELECTRON
PARAMAGNETIC RESONANCE SPECTROSCOPY
Jelena Đoković1*, Sotiria Demisli2, Vassiliki Papadimitrio ...
Neuroimmune aspects of mood, anxiety and cognitive effects of leads/drug candidates acting at gabaa and/or sigma‐2 receptors: in vitro/in vivo delineation by nano‐ and hipsc‐based platforms / Neuroimunski aspekti efekata vodećih jedinjenja/lekova kandidata koji deluju preko gabaa i/ili sigma‐2 receptora na raspoloženje, anksioznost i kogniciju: in vitro/in vivo delineacija primenom nano‐ i hipsc platformi
(8. Kongres farmaceuta Srbije; 12.-15. oktobar, Beograd, Srbija, 2022)
Mood, anxiety and cognitive symptoms in psychiatry and neurology represent a significant worldwide burden. Due to difficulties in disease modeling and drug delivering to the site of action, as well as gaps in in vitro/in ...
Design of tailor-made biocompatible nanocarrier for novel pyrazoloquinolinone ligand (CW-02-79) based on comprehensive evaluation of critical physicochemical descriptors
(International Association of Physical Chemists, 2023)
Design of tailor-made biocompatible nanocarrier for novel pyrazoloquinolinone ligand (CW-02-79) based on comprehensive evaluation of critical physicochemical descriptors
Tijana Stanković1, Tanja Ilić1, Ivana Pantelić1, ...
Sizing up the nanomedicines: a thorough examination of techniques and data interpretation
(French Society for Nanomedicine (SFNano), 2023)
Size is a universal and first in mind property relevant for nanomedicine/nanomaterial
characterization, representing the most suitable measurand. However, due to the acknowledged
lack of standardized protocols that are ...
The impact of the aqueous phase on the physicochemical characteristics of nanoemulsions loaded with patent protected compound GL-II-73
(International Society of Drug Delivery Sciences and Technology (APGI)International Association for Pharmaceutical Technology (APV)Italian Society of Technology and Legislation (S.T.E.L.F), 2024)
INTRODUCTION Temporal lobe epilepsy is characterized by seizures, but can also be associated with mental health problems for which there are no clear treatment regimens. A proprietary compound, GL-II-73 - (4R)-8-ethynyl- ...
Overcoming the low solubility of novel pyrazoloquinolinone ligand (CW-02-79) by combination of drug-phospholipid complex and nanoemulsion technology: design and physicochemical evaluation
(International Society of Drug Delivery Sciences and Technology (APGI)International Association for Pharmaceutical Technology (APV)Italian Society of Technology and Legislation (S.T.E.L.F), 2024)
The low aqueous and oil solubility of the novel
pyrazoloquinolinone ligand (CW-02-79) with significant
binding affinity for sigma-2 receptors in the brain hinders
the development of conventional parenteral formulations
and ...
Deciphering ciprofloxacin-induced neurotoxicity: behavioral and molecular profiling of ciprofloxacin treatment in rats
(European College of Neuropsychopharmacology (ECNP), 2023)
Introduction: Ciprofloxacin is a fluoroquinolone antibiotic commonly used to treat various bacterial infections, with a potential to induce adverse mood effects in patients. Since the molecular mechanism of ciprofloxacin-induced ...
Reward-related impulsivity as a possible surrogate marker of motivation in aging Sprague-Dawley rats
(European College of Neuropsychopharmacology (ECNP), 2023)
Introduction: Impulsivity is an umbrella term that encompasses many subdomains, most of which rely on the decision-making processes. It is reported that in the process of healthy aging, the two dimensions of impulse control, ...