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Cytotoxic and antioxidant activity of Achillea alexandri-regis
dc.creator | Kundaković, Tatjana | |
dc.creator | Stanojković, Tatjana | |
dc.creator | Juranić, Zorica | |
dc.creator | Kovačević, Nada | |
dc.date.accessioned | 2019-09-02T11:00:56Z | |
dc.date.available | 2019-09-02T11:00:56Z | |
dc.date.issued | 2005 | |
dc.identifier.issn | 0031-7144 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/590 | |
dc.description.abstract | The cytotoxicity and antioxidant properties of herb extracts of Achillea alexandri-regis were studied. Combined chloroform and ethylacetate extracts exhibited a pronounced cytotoxic effect against HeLa cancer cells (IC50 = 25.92 +/- 4.96 mu g/ml), and lower cytotoxicity against K562 leukemia cells (IC50 = 48.59 +/- 18.31 mu g/ml). The methanol extract was found to be a moderately cytotoxic in vitro agent against HeLa and K562 cells. No suppressive activity was detected on non-malignant peripheral blood mononuclear cells (PBMC). The antioxidant activity of the methanol extract was assessed by DPPH radical scavenging. The methanol extract of A. alexandri-regis showed concentration dependent DPPH radical scavenging activity with IC50 = 36.14 +/- 0.05 | en |
dc.publisher | Govi-Verlag Pharmazeutischer Verlag Gmbh, Eschborn | |
dc.rights | restrictedAccess | |
dc.source | Pharmazie | |
dc.title | Cytotoxic and antioxidant activity of Achillea alexandri-regis | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Ковачевић, Нада; Кундаковић, Татјана; Станојковић, Татјана; Јуранић, Зорица; | |
dc.citation.volume | 60 | |
dc.citation.issue | 4 | |
dc.citation.spage | 319 | |
dc.citation.epage | 320 | |
dc.citation.other | 60(4): 319-320 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000228532600018 | |
dc.identifier.pmid | 15881617 | |
dc.identifier.scopus | 2-s2.0-17644390239 | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_farfar_590 | |
dc.type.version | publishedVersion |
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