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Evaluation of adrenaline-induced DNA damage in vitro by comet assay
(National Health Institute Dr. Ricardo JorgeInstitute of Public Health of the University of Porto (ISPUP), 2018)
Experimental evidence has shown the ability of adrenaline to cause changes in DNA, affirming that damaging effects occurs during the oxidation of the hormone. Longterm research in this area would surmise that the mechanisms ...
Unexpected effect of dry olive leaf extract (DOLE) before and after CaNa2EDTA chelation therapy in comet assay in lead intoxicated workers
(International Congress on Occupational & Environmental Toxicology - ICOETox 2016, 2016)
The CaNa2EDTA chelation is a standard therapy for lead (Pb) intoxication in occupationally exposed workers. Application of antioxidant nutrients through exogenous supplementation is often practiced with the chelation ...
Evaluation of repair kinetics of oxidative damaged DNA in peripheral blood leukocytes treated with chaga mushroom (Inonotus obliquus) extract in vitro
(International Comet Assay Working Group (ICAWG), 2019)
Inonotus obliquus, edible medicinal mushroom found in northern hemisphere, is widely used for the prevention and treatment of cancer, diabetes, colitis and asthma. Its bioactives, triterpens, polysaccharides and polyphenols ...
Evaluation of the effects of ephedrine on human lymphocytes in the comet assay / Evaluacija dejstva efedrina na limfocite čoveka u komet testu
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2011)
Ephedrine, a natural alkaloid from plants of the genus Ephedra, has a chemical structure similar to catecholamines. It is well established that catecholamines (adraneline, noradrenaline and dopamine) cause genotoxic and ...
Dry olive leaf extract supplementation reduces DNA damage in chronic rheumatoid arthritis patients
(Center for Molecular Medicine Cologne, University of Cologne, 2014)
Increased oxidative stress caused by chronic inflammation is one of the underlying mechanisms in etiology of rheumatoid arthritis (RA). Reactive oxygen species produced during inflammatory response target cells DNA leading ...
Implications of oxidative stress in occupational exposure to lead on a cellular level
(Taylor & Francis Ltd, Abingdon, 2015)
The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and ...
Salvianolic acid B reduces hydrogen peroxide induced DNA damage in human peripheral blood cells in vitro
(International Comet Assay Working Group (ICAWG), 2017)
Salvianolic acid B (Sal B) is a polyphenol compound derived from the Salvia miltiorrhiza plant which showed multitude of biological activities in vitro, including antioxidant, anti-inflammatory, cytotoxic and neuroprotective ...
Antigenotoxic effect of quercetin on thyroxine-induced DNA damage in human whole blood cells in vitro
(Institute for Genetic Engineering and Biotechnology, University of Sarajevo, 2019)
The binding of thyroid hormones to specific nuclear receptors in target cells induces synthesis of enzymes associated with redox processes, leading to the formation of reactive oxygen species (ROS), which can cause damage ...
Protective Effects Of Olive Leaf Extract On Inflammatory Activation Of Endothelial Cells
(Elsevier, 2019)
Background and Aims: Olive leaf extract (OLE) has been traditionally used due to its anti-inflammatory and anti-atherogenic effects. ...
Antigenotoxic effects of Biochaga and Dihydroquercetin (taxifolin) on H2O2 induced DNA damage in human WBC
(Turkish Society of Toxicology, 2019)
The health benefits of natural products have long been recognized. Consumption of dietary compounds such as supplements, provides an alternative source of natural products to those obtained from the diet. There is a growing ...