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Unexpected effect of dry olive leaf extract (DOLE) before and after CaNa2EDTA chelation therapy in comet assay in lead intoxicated workers
(International Congress on Occupational & Environmental Toxicology - ICOETox 2016, 2016)
The CaNa2EDTA chelation is a standard therapy for lead (Pb) intoxication in occupationally exposed workers. Application of antioxidant nutrients through exogenous supplementation is often practiced with the chelation ...
Evaluation of repair kinetics of oxidative damaged DNA in peripheral blood leukocytes treated with chaga mushroom (Inonotus obliquus) extract in vitro
(International Comet Assay Working Group (ICAWG), 2019)
Inonotus obliquus, edible medicinal mushroom found in northern hemisphere, is widely used for the prevention and treatment of cancer, diabetes, colitis and asthma. Its bioactives, triterpens, polysaccharides and polyphenols ...
Salvianolic acid B reduces hydrogen peroxide induced DNA damage in human peripheral blood cells in vitro
(International Comet Assay Working Group (ICAWG), 2017)
Salvianolic acid B (Sal B) is a polyphenol compound derived from the Salvia miltiorrhiza plant which showed multitude of biological activities in vitro, including antioxidant, anti-inflammatory, cytotoxic and neuroprotective ...
Antigenotoxic effect of quercetin on thyroxine-induced DNA damage in human whole blood cells in vitro
(Institute for Genetic Engineering and Biotechnology, University of Sarajevo, 2019)
The binding of thyroid hormones to specific nuclear receptors in target cells induces synthesis of enzymes associated with redox processes, leading to the formation of reactive oxygen species (ROS), which can cause damage ...
Assessment of DNA damage in blood, liver and kidney cells in a hypertensive rat model using comet assay
(Institute for Genetic Engineering and Biotechnology, University of Sarajevo, 2019)
Hypertension is one of the primary risk factors for heart disease and stroke, the leading causes of death worldwide. Numerous factors have been implicated in the pathophysiology of hypertension: endothelial dysfunction, ...
Antigenotoxic effects of Biochaga and Dihydroquercetin (taxifolin) on H2O2 induced DNA damage in human WBC
(Turkish Society of Toxicology, 2019)
The health benefits of natural products have long been recognized. Consumption of dietary compounds such as supplements, provides an alternative source of natural products to those obtained from the diet. There is a growing ...