Ivanović, Nevena

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  • Ivanović, Nevena (52)

Author's Bibliography

Phthalate content in toy samples available on the market of the Republic of Serbia

Ivanović, Nevena; Milenković, Milan; Protić, Ana; Jovanović, Verica; Đorđević, Brižita; Dodevska, Margarita

(Royal Society of Chemistry, 2024)

TY  - JOUR
AU  - Ivanović, Nevena
AU  - Milenković, Milan
AU  - Protić, Ana
AU  - Jovanović, Verica
AU  - Đorđević, Brižita
AU  - Dodevska, Margarita
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5738
AB  - Phthalates are a family of synthetic chemicals commonly used as plasticizers for polyvinyl chloride-based polymers. They are used in a variety of commercial consumer products, including children's toys. Exposure to phthalates is associated with various adverse health effects, such as developmental and reproductive disorders, liver and kidney toxicity, etc. In the European Union, but also in the Republic of Serbia, restrictions have been imposed on the presence of seven phthalates in toys. In addition, the European Union has established the Rapid Alert System for Dangerous Non-Food Products (RAPEX) to protect consumers across borders by preventing or restricting the sale and use of non-food articles, including children's toys, that pose a significant health and safety risk. In this work, 118 samples of children's toys from the market of the Republic of Serbia were analysed for the presence of all seven restricted phthalates using the HPLC-DAD method. We also comprehensively analysed the RAPEX notifications of toys posing a chemical risk due to the presence of phthalates from 2012 to 2022. In total, 23.7% of the tested toy samples contained one or more phthalates above 0.1% w/w, which corresponds to the legal limit. DEHP was found above the limit in all non-compliant toy samples, followed by DBP, DINP, BBP and DIDP. DIBP and DNOP were not found in any of the samples. In general, phthalates were present in the tested samples in concentrations ranging from <LOQ to 36.6% (w/w), depending on the type of phthalate detected, with DINP detected in the highest concentration. In the period 2012–2022, 1192 alerts related to non-compliant toys were registered due to the illegal presence of phthalates. Among them, DEHP was present in 94.79% of toy samples, while it was the only phthalate in 58.4% of toy samples. Furthermore, DEHP was present in the highest concentration of about 18.5% (w/w), with a maximum detected concentration of up to 55% (w/w). The results presented in this article show that even more than a decade after the introduction of the ban and restrictions on phthalates in toys, toys are still a significant source of children's exposure to phthalates.
PB  - Royal Society of Chemistry
T2  - Analytical Methods
T1  - Phthalate content in toy samples available on the market of the Republic of Serbia
DO  - 10.1039/d4ay01092b
ER  - 
@article{
author = "Ivanović, Nevena and Milenković, Milan and Protić, Ana and Jovanović, Verica and Đorđević, Brižita and Dodevska, Margarita",
year = "2024",
abstract = "Phthalates are a family of synthetic chemicals commonly used as plasticizers for polyvinyl chloride-based polymers. They are used in a variety of commercial consumer products, including children's toys. Exposure to phthalates is associated with various adverse health effects, such as developmental and reproductive disorders, liver and kidney toxicity, etc. In the European Union, but also in the Republic of Serbia, restrictions have been imposed on the presence of seven phthalates in toys. In addition, the European Union has established the Rapid Alert System for Dangerous Non-Food Products (RAPEX) to protect consumers across borders by preventing or restricting the sale and use of non-food articles, including children's toys, that pose a significant health and safety risk. In this work, 118 samples of children's toys from the market of the Republic of Serbia were analysed for the presence of all seven restricted phthalates using the HPLC-DAD method. We also comprehensively analysed the RAPEX notifications of toys posing a chemical risk due to the presence of phthalates from 2012 to 2022. In total, 23.7% of the tested toy samples contained one or more phthalates above 0.1% w/w, which corresponds to the legal limit. DEHP was found above the limit in all non-compliant toy samples, followed by DBP, DINP, BBP and DIDP. DIBP and DNOP were not found in any of the samples. In general, phthalates were present in the tested samples in concentrations ranging from <LOQ to 36.6% (w/w), depending on the type of phthalate detected, with DINP detected in the highest concentration. In the period 2012–2022, 1192 alerts related to non-compliant toys were registered due to the illegal presence of phthalates. Among them, DEHP was present in 94.79% of toy samples, while it was the only phthalate in 58.4% of toy samples. Furthermore, DEHP was present in the highest concentration of about 18.5% (w/w), with a maximum detected concentration of up to 55% (w/w). The results presented in this article show that even more than a decade after the introduction of the ban and restrictions on phthalates in toys, toys are still a significant source of children's exposure to phthalates.",
publisher = "Royal Society of Chemistry",
journal = "Analytical Methods",
title = "Phthalate content in toy samples available on the market of the Republic of Serbia",
doi = "10.1039/d4ay01092b"
}
Ivanović, N., Milenković, M., Protić, A., Jovanović, V., Đorđević, B.,& Dodevska, M.. (2024). Phthalate content in toy samples available on the market of the Republic of Serbia. in Analytical Methods
Royal Society of Chemistry..
https://doi.org/10.1039/d4ay01092b
Ivanović N, Milenković M, Protić A, Jovanović V, Đorđević B, Dodevska M. Phthalate content in toy samples available on the market of the Republic of Serbia. in Analytical Methods. 2024;.
doi:10.1039/d4ay01092b .
Ivanović, Nevena, Milenković, Milan, Protić, Ana, Jovanović, Verica, Đorđević, Brižita, Dodevska, Margarita, "Phthalate content in toy samples available on the market of the Republic of Serbia" in Analytical Methods (2024),
https://doi.org/10.1039/d4ay01092b . .

Butyrate- and Beta-Hydroxybutyrate-Mediated Effects of Interventions with Pro- and Prebiotics, Fasting, and Caloric Restrictions on Depression: A Systematic Review and Meta-Analysis

Breuling, Marian; Tomeva, Elena; Ivanović, Nevena; Haslberger, Alexander

(MDPI, 2024)

TY  - JOUR
AU  - Breuling, Marian
AU  - Tomeva, Elena
AU  - Ivanović, Nevena
AU  - Haslberger, Alexander
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5722
AB  - To examine the butyrate- and beta-hydroxybutyrate (BHB)-modulated effects of pre- and probiotic interventions, fasting, and caloric restriction interventions, a systematic literature review was carried out with a subsequent meta-analysis. Three pre-and probiotic intervention randomized control trials (RCTs) were included in the meta-analysis. A significant increase in butyrate (standardized mean difference (SMD) [confidence interval (CI)] 0.34; [0.02–0.67]) and an improvement in depression scores (SMD [CI] 0.15, [−0.35–0.70]) through pre- and probiotic interventions were shown in the meta-analysis. The intervention duration of the included studies ranged from three days to four weeks, with the examined population being healthy adults. Butyrate was measured in either plasma or feces, and the depression score was obtained under the Swedish core affect scale, the hospital anxiety and depression scale (HADS), or the depression, anxiety, and stress scale—21 items (DASS-21). In addition to butyrate, the total SCFA concentration also seems to be positively associated with pre- and probiotic administration (SMD [CI] 0.55 [0.15–0.95]). Despite the significant short-chain fatty acid (SCFA) and butyrate concentration changes, no significant correlation between butyrate and depression or between SCFAs and depression could be shown through linear regression models. Nevertheless, the regression coefficient b1 = 1.57 (p = 0.17) for butyrate suggests a strong, positive connection between butyrate and depression. Additionally, three studies were qualitatively analyzed, examining fasting as an intervention and revealing a connection between fasting, BHB, and depression. The association between fasting, BHB, and depression or mood elevation appeared to be related to BHB concentrations, which may be due to the similar biochemical properties of BHB and butyrate. Furthermore, caloric restrictions as alternatives to fasting were proposed as potential long-term interventions.
PB  - MDPI
T2  - Life
T1  - Butyrate- and Beta-Hydroxybutyrate-Mediated Effects of Interventions with Pro- and Prebiotics, Fasting, and Caloric Restrictions on Depression: A Systematic Review and Meta-Analysis
VL  - 14
IS  - 7
DO  - 10.3390/life14070787
ER  - 
@article{
author = "Breuling, Marian and Tomeva, Elena and Ivanović, Nevena and Haslberger, Alexander",
year = "2024",
abstract = "To examine the butyrate- and beta-hydroxybutyrate (BHB)-modulated effects of pre- and probiotic interventions, fasting, and caloric restriction interventions, a systematic literature review was carried out with a subsequent meta-analysis. Three pre-and probiotic intervention randomized control trials (RCTs) were included in the meta-analysis. A significant increase in butyrate (standardized mean difference (SMD) [confidence interval (CI)] 0.34; [0.02–0.67]) and an improvement in depression scores (SMD [CI] 0.15, [−0.35–0.70]) through pre- and probiotic interventions were shown in the meta-analysis. The intervention duration of the included studies ranged from three days to four weeks, with the examined population being healthy adults. Butyrate was measured in either plasma or feces, and the depression score was obtained under the Swedish core affect scale, the hospital anxiety and depression scale (HADS), or the depression, anxiety, and stress scale—21 items (DASS-21). In addition to butyrate, the total SCFA concentration also seems to be positively associated with pre- and probiotic administration (SMD [CI] 0.55 [0.15–0.95]). Despite the significant short-chain fatty acid (SCFA) and butyrate concentration changes, no significant correlation between butyrate and depression or between SCFAs and depression could be shown through linear regression models. Nevertheless, the regression coefficient b1 = 1.57 (p = 0.17) for butyrate suggests a strong, positive connection between butyrate and depression. Additionally, three studies were qualitatively analyzed, examining fasting as an intervention and revealing a connection between fasting, BHB, and depression. The association between fasting, BHB, and depression or mood elevation appeared to be related to BHB concentrations, which may be due to the similar biochemical properties of BHB and butyrate. Furthermore, caloric restrictions as alternatives to fasting were proposed as potential long-term interventions.",
publisher = "MDPI",
journal = "Life",
title = "Butyrate- and Beta-Hydroxybutyrate-Mediated Effects of Interventions with Pro- and Prebiotics, Fasting, and Caloric Restrictions on Depression: A Systematic Review and Meta-Analysis",
volume = "14",
number = "7",
doi = "10.3390/life14070787"
}
Breuling, M., Tomeva, E., Ivanović, N.,& Haslberger, A.. (2024). Butyrate- and Beta-Hydroxybutyrate-Mediated Effects of Interventions with Pro- and Prebiotics, Fasting, and Caloric Restrictions on Depression: A Systematic Review and Meta-Analysis. in Life
MDPI., 14(7).
https://doi.org/10.3390/life14070787
Breuling M, Tomeva E, Ivanović N, Haslberger A. Butyrate- and Beta-Hydroxybutyrate-Mediated Effects of Interventions with Pro- and Prebiotics, Fasting, and Caloric Restrictions on Depression: A Systematic Review and Meta-Analysis. in Life. 2024;14(7).
doi:10.3390/life14070787 .
Breuling, Marian, Tomeva, Elena, Ivanović, Nevena, Haslberger, Alexander, "Butyrate- and Beta-Hydroxybutyrate-Mediated Effects of Interventions with Pro- and Prebiotics, Fasting, and Caloric Restrictions on Depression: A Systematic Review and Meta-Analysis" in Life, 14, no. 7 (2024),
https://doi.org/10.3390/life14070787 . .

Effects of probiotic intervention on obesity- related miRNAs

Okuka, Nina; Berit, Hippe; Đorđević, Brižita; Ivanović, Nevena

(Savez farmaceutskih udruženja Srbije, Beograd, 2024)

TY  - JOUR
AU  - Okuka, Nina
AU  - Berit, Hippe
AU  - Đorđević, Brižita
AU  - Ivanović, Nevena
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5715
AB  - Obesity is considered to be a chronic complex disease that increases the risk of diabetes,
heart diseases and certain cancers. According to the literature, in obese people the gastrointestinal
microbiota is disturbed, which could be the cause of the onset of obesity and related diseases.
Moreover, there are small non-coding RNAs (microRNAs) that are disturbed in obesity, which
are also considered to be a possible mechanism of probiotics’ action. Certain microRNAs are
involved in the development and metabolism of adipose tissue cells, as well as the secretion and
action of insulin, showing that changed expression of certain miRNAs could have a significant
impact on the onset and development of obesity and obesity-related diseases. Thus, miRNAs are
considered to be possible markers for the diagnosis and prognosis of various metabolic diseases,
and possible therapeutic targets for the treatment of obesity and related diseases. Considering the
growing need of the healthcare system for nutraceuticals and dietary supplements that present
effective and safe medical nutritive therapy in obese individuals, this work aimed to assess the
beneficial effects of probiotics on obesity-related microRNAs. In this review, we described the
role of microRNAs and probiotics in obesity and the association between probiotics and obesity-
related microRNAs. Circulating miRNAs’ profile in obese individuals significantly differs from
that of normal-weight individuals. miRNAs such as miR-155, miR-221, miR-24-3p, and miR-
181a are over-expressed, while miR-26b and 125a are under-expressed in obese patients
compared to non-obese individuals. It has been found that supplementation with Bifidobacterium bifidum and Lactobacillus acidophilus could downregulate the expression of miR-155 and miR-
221, and upregulate the expression of miR-26b. Supplementation with a probiotic formulation
containing S. boulardii, L. plantarum 299v, and octacosanol led to the downregulation of miR-
155 and miR-24-3p expression. miR-125a and miR-181a were upregulated and downregulated,
respectively, after the intervention with L. delbrueckii and L. rhamnosus. After reviewing the
available literature, we can conclude that probiotics have beneficial effects on microRNAs altered
in obesity, which could provide an effective strategy for the management of obesity.
AB  - Gojaznost se smatra hroničnom, kompleksnom bolešću koja povećava rizik od nastanka drugih oboljenja poput dijabetesa, kardiovaskularnih oboljenja i određenih karcinoma. Prema literaturnim podacima, kod gojaznih osoba dolazi do narušavanja gastrointestinalne mikrobiote, što nadalje može biti uzrok razvoja gojaznosti i bolesti povezanih sa gojaznošću. Dodatno, postoje male nekodirajuće RNK (mikroRNK) čije su koncentracije promenjene kod gojaznih osoba u poređenju sa osobama normalne telesne mase. Takođe, mikroRNK se smatraju mogućim mehanizmom delovanja probiotika. Određene mikroRNK se smatraju ključnim u procesima razvoja i metabolizma masnog tkiva, kao i u procesima sinteze i delovanja hormona insulina, time ukazujući na to da bi promene u ekspresiji određenih miRNK mogle imati značajan uticaj na nastanak i razvoj gojaznosti i bolesti povezanih sa gojaznošću. Zbog navedenog, miRNK se smatraju mogućim markerima za dijagnozu i praćenje metaboličkih bolesti, ali se razmatraju i kao moguća terapija u tretmanu gojaznosti i oboljenja povezanih sa gojaznošću. U svetlu rastućih potreba sistema zdravstvene zaštite u pogledu dodataka ishrani i nutraceutika koji pružaju efikasnu i bezbednu podršku medicinskoj nutritivnoj terapiji kod gojaznosti, cilj ovog rada bio je da se istraže korisni efekti probiotika na mikroRNK povezane sa gojaznošću. U ovom narativnom pregledu opisali smo ulogu probiotika i mikroRNK u gojaznosti, kao i moguću povezanost probiotika sa mikroRNK koje su izmenjene kod gojaznih ljudi. Profil cirkulišućih miRNK se značajno razlikuje kod gojaznih osoba u poređenju sa osobama normalne telesne mase. Ekspresija miRNK poput miR-155, miR-221, miR-24-3p i miR-181a je značajno povišena, dok je ekspresija miR-26b i miR-125a snižena kod gojaznih osoba u poređenju sa osobama normalne telesne mase. Suplementacija sa Bifidobacterium bifidum i Lactobacillus acidophilus probiotskim sojevima snižava ekspresiju miR-155 i miR-221, dok je ekspresija miR-26b povišena nakon suplementacije ovim sojevima. Probiotska formulacija koja sadrži kombinaciju S. boulardii, L. plantarum 299v i oktakozanola dovela je do smanjenja ekspresije miR-155 i miR-24-3p. Ekspresija miR-125a je bila povećana, dok je ekspresija miR-181a bila snižena nakon suplementacije sojevima L. delbrueckii and L. rhamnosus. Nakon pregleda dostupne literature, možemo zaključiti da probiotici imaju pozitivno dejstvo na mikroRNK izmenjene kod gojaznih osoba, te da bi primena probiotika mogla biti efikasna strategija u tretmanu gojaznosti.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
PB  - Univerzitet u Beogradu - Farmaceutski fakultet
T2  - Arhiv za farmaciju
T1  - Effects of probiotic intervention on obesity- related miRNAs
T1  - Efekti upotrebe probiotika na mikroRNK povezane sa gojaznošću
VL  - 74
IS  - 3
SP  - 391
EP  - 409
DO  - 10.5937/arhfarm74-50645
ER  - 
@article{
author = "Okuka, Nina and Berit, Hippe and Đorđević, Brižita and Ivanović, Nevena",
year = "2024",
abstract = "Obesity is considered to be a chronic complex disease that increases the risk of diabetes,
heart diseases and certain cancers. According to the literature, in obese people the gastrointestinal
microbiota is disturbed, which could be the cause of the onset of obesity and related diseases.
Moreover, there are small non-coding RNAs (microRNAs) that are disturbed in obesity, which
are also considered to be a possible mechanism of probiotics’ action. Certain microRNAs are
involved in the development and metabolism of adipose tissue cells, as well as the secretion and
action of insulin, showing that changed expression of certain miRNAs could have a significant
impact on the onset and development of obesity and obesity-related diseases. Thus, miRNAs are
considered to be possible markers for the diagnosis and prognosis of various metabolic diseases,
and possible therapeutic targets for the treatment of obesity and related diseases. Considering the
growing need of the healthcare system for nutraceuticals and dietary supplements that present
effective and safe medical nutritive therapy in obese individuals, this work aimed to assess the
beneficial effects of probiotics on obesity-related microRNAs. In this review, we described the
role of microRNAs and probiotics in obesity and the association between probiotics and obesity-
related microRNAs. Circulating miRNAs’ profile in obese individuals significantly differs from
that of normal-weight individuals. miRNAs such as miR-155, miR-221, miR-24-3p, and miR-
181a are over-expressed, while miR-26b and 125a are under-expressed in obese patients
compared to non-obese individuals. It has been found that supplementation with Bifidobacterium bifidum and Lactobacillus acidophilus could downregulate the expression of miR-155 and miR-
221, and upregulate the expression of miR-26b. Supplementation with a probiotic formulation
containing S. boulardii, L. plantarum 299v, and octacosanol led to the downregulation of miR-
155 and miR-24-3p expression. miR-125a and miR-181a were upregulated and downregulated,
respectively, after the intervention with L. delbrueckii and L. rhamnosus. After reviewing the
available literature, we can conclude that probiotics have beneficial effects on microRNAs altered
in obesity, which could provide an effective strategy for the management of obesity., Gojaznost se smatra hroničnom, kompleksnom bolešću koja povećava rizik od nastanka drugih oboljenja poput dijabetesa, kardiovaskularnih oboljenja i određenih karcinoma. Prema literaturnim podacima, kod gojaznih osoba dolazi do narušavanja gastrointestinalne mikrobiote, što nadalje može biti uzrok razvoja gojaznosti i bolesti povezanih sa gojaznošću. Dodatno, postoje male nekodirajuće RNK (mikroRNK) čije su koncentracije promenjene kod gojaznih osoba u poređenju sa osobama normalne telesne mase. Takođe, mikroRNK se smatraju mogućim mehanizmom delovanja probiotika. Određene mikroRNK se smatraju ključnim u procesima razvoja i metabolizma masnog tkiva, kao i u procesima sinteze i delovanja hormona insulina, time ukazujući na to da bi promene u ekspresiji određenih miRNK mogle imati značajan uticaj na nastanak i razvoj gojaznosti i bolesti povezanih sa gojaznošću. Zbog navedenog, miRNK se smatraju mogućim markerima za dijagnozu i praćenje metaboličkih bolesti, ali se razmatraju i kao moguća terapija u tretmanu gojaznosti i oboljenja povezanih sa gojaznošću. U svetlu rastućih potreba sistema zdravstvene zaštite u pogledu dodataka ishrani i nutraceutika koji pružaju efikasnu i bezbednu podršku medicinskoj nutritivnoj terapiji kod gojaznosti, cilj ovog rada bio je da se istraže korisni efekti probiotika na mikroRNK povezane sa gojaznošću. U ovom narativnom pregledu opisali smo ulogu probiotika i mikroRNK u gojaznosti, kao i moguću povezanost probiotika sa mikroRNK koje su izmenjene kod gojaznih ljudi. Profil cirkulišućih miRNK se značajno razlikuje kod gojaznih osoba u poređenju sa osobama normalne telesne mase. Ekspresija miRNK poput miR-155, miR-221, miR-24-3p i miR-181a je značajno povišena, dok je ekspresija miR-26b i miR-125a snižena kod gojaznih osoba u poređenju sa osobama normalne telesne mase. Suplementacija sa Bifidobacterium bifidum i Lactobacillus acidophilus probiotskim sojevima snižava ekspresiju miR-155 i miR-221, dok je ekspresija miR-26b povišena nakon suplementacije ovim sojevima. Probiotska formulacija koja sadrži kombinaciju S. boulardii, L. plantarum 299v i oktakozanola dovela je do smanjenja ekspresije miR-155 i miR-24-3p. Ekspresija miR-125a je bila povećana, dok je ekspresija miR-181a bila snižena nakon suplementacije sojevima L. delbrueckii and L. rhamnosus. Nakon pregleda dostupne literature, možemo zaključiti da probiotici imaju pozitivno dejstvo na mikroRNK izmenjene kod gojaznih osoba, te da bi primena probiotika mogla biti efikasna strategija u tretmanu gojaznosti.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd, Univerzitet u Beogradu - Farmaceutski fakultet",
journal = "Arhiv za farmaciju",
title = "Effects of probiotic intervention on obesity- related miRNAs, Efekti upotrebe probiotika na mikroRNK povezane sa gojaznošću",
volume = "74",
number = "3",
pages = "391-409",
doi = "10.5937/arhfarm74-50645"
}
Okuka, N., Berit, H., Đorđević, B.,& Ivanović, N.. (2024). Effects of probiotic intervention on obesity- related miRNAs. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 74(3), 391-409.
https://doi.org/10.5937/arhfarm74-50645
Okuka N, Berit H, Đorđević B, Ivanović N. Effects of probiotic intervention on obesity- related miRNAs. in Arhiv za farmaciju. 2024;74(3):391-409.
doi:10.5937/arhfarm74-50645 .
Okuka, Nina, Berit, Hippe, Đorđević, Brižita, Ivanović, Nevena, "Effects of probiotic intervention on obesity- related miRNAs" in Arhiv za farmaciju, 74, no. 3 (2024):391-409,
https://doi.org/10.5937/arhfarm74-50645 . .

Dietary interventions in obesity: a narrative review

Dudašova Petrovičova, Olina; Đuričić, Ivana; Ivanović, Nevena; Dabetić, Nevena; Dodevska, Margarita; Ilić, Tijana

(Savez farmaceutskih udruženja Srbije, Beograd, 2024)

TY  - JOUR
AU  - Dudašova Petrovičova, Olina
AU  - Đuričić, Ivana
AU  - Ivanović, Nevena
AU  - Dabetić, Nevena
AU  - Dodevska, Margarita
AU  - Ilić, Tijana
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5712
AB  - The World Health Organization highlights that in 2022 around 890 million adults and 160
million children and adolescents globally were obese, indicating a significant public health
concern. Obesity results from an energy imbalance, where calorie intake exceeds calorie
expenditure, leading to an increase in the size of fat cells and subsequently to metabolic
dysfunction and inflammation. Management of obesity involves lifestyle adjustments, including
dietary modifications and increased physical activity, with calorie-restricted diets and meal
replacements often recommended to achieve weight loss and lower overall energy intake. Weight
loss programs include a low-carbohydrate, low-fat, or high-protein diet. In addition, the influence
of the Mediterranean diet and dietary fiber on regulating body weight has been increasingly
studied in recent years. Dietary products for weight control, including meal replacements, are
regulated and offer options for people who want to lose weight. More personalized nutrition
approaches are emerging that focus on individual needs, genetic factors and gut microbiota
composition to optimize health outcomes. Although personalized nutrition promises to explain
how nutrition-related health problems may be solved, further research should investigate health
outcomes in individuals living with obesity.
AB  - Prema podacima Svetske zdravstvene organizacije, 2022. godine je oko 890 miliona odraslih i 160 miliona dece i adolescenata širom sveta bilo gojazno, što daje povoda za značajnu zabrinutost za javno zdravlje. Gojaznost nastaje usled prekomernog unosa i smanjene potrošnje kalorija tokom dužeg vremenskog perioda, a manifestuje se uvećanjem masnog tkiva, telesne težine i pojavom metaboličkih poremećaja. Tretman gojaznosti podrazumeva promene u načinu ishrane i stilu života. Dijete sa ograničenim unosom kalorija i zamene za obroke se često preporučuju za postizanje gubitka telesne težine i smanjenje ukupnog unosa energije. Dijete obuhvataju ishranu sa niskim sadržajem ugljenih hidrata, dijetu sa niskim sadržajem masti ili visokoproteinsku dijetu. Pored toga, poslednjih godina se sve više ispituje uticaj mediteranske ishrane i dijetetskih vlakana u regulaciji telesne težine. Dijetetski proizvodi namenjeni regulaciji telesne težine dizajnirani su da zamene obroke i nude opcije za pojedince koji žele da redukuju telesnu masu. Pojavljuju se personalizovani pristupi ishrani koji se fokusiraju na individualne potrebe, genetske faktore i sastav crevne mikrobiote kako bi se optimizovali zdravstveni ishodi. Iako personalizovana ishrana ima sve veću primenu u nutritivnoj terapiji, potrebna su dalja istraživanja kako bi se bolje razumela njena efikasnost kod pacijenata sa gojaznošću.
PB  - Savez farmaceutskih udruženja Srbije, Beograd
PB  - Univerzitet u Beogradu - Farmaceutski fakultet
T2  - Arhiv za farmaciju
T1  - Dietary interventions in obesity: a narrative review
T1  - Dijetarne intervencije kod gojaznosti: pregledni rad
VL  - 74
IS  - 3
SP  - 281
EP  - 297
DO  - 10.5937/arhfarm74-50457
ER  - 
@article{
author = "Dudašova Petrovičova, Olina and Đuričić, Ivana and Ivanović, Nevena and Dabetić, Nevena and Dodevska, Margarita and Ilić, Tijana",
year = "2024",
abstract = "The World Health Organization highlights that in 2022 around 890 million adults and 160
million children and adolescents globally were obese, indicating a significant public health
concern. Obesity results from an energy imbalance, where calorie intake exceeds calorie
expenditure, leading to an increase in the size of fat cells and subsequently to metabolic
dysfunction and inflammation. Management of obesity involves lifestyle adjustments, including
dietary modifications and increased physical activity, with calorie-restricted diets and meal
replacements often recommended to achieve weight loss and lower overall energy intake. Weight
loss programs include a low-carbohydrate, low-fat, or high-protein diet. In addition, the influence
of the Mediterranean diet and dietary fiber on regulating body weight has been increasingly
studied in recent years. Dietary products for weight control, including meal replacements, are
regulated and offer options for people who want to lose weight. More personalized nutrition
approaches are emerging that focus on individual needs, genetic factors and gut microbiota
composition to optimize health outcomes. Although personalized nutrition promises to explain
how nutrition-related health problems may be solved, further research should investigate health
outcomes in individuals living with obesity., Prema podacima Svetske zdravstvene organizacije, 2022. godine je oko 890 miliona odraslih i 160 miliona dece i adolescenata širom sveta bilo gojazno, što daje povoda za značajnu zabrinutost za javno zdravlje. Gojaznost nastaje usled prekomernog unosa i smanjene potrošnje kalorija tokom dužeg vremenskog perioda, a manifestuje se uvećanjem masnog tkiva, telesne težine i pojavom metaboličkih poremećaja. Tretman gojaznosti podrazumeva promene u načinu ishrane i stilu života. Dijete sa ograničenim unosom kalorija i zamene za obroke se često preporučuju za postizanje gubitka telesne težine i smanjenje ukupnog unosa energije. Dijete obuhvataju ishranu sa niskim sadržajem ugljenih hidrata, dijetu sa niskim sadržajem masti ili visokoproteinsku dijetu. Pored toga, poslednjih godina se sve više ispituje uticaj mediteranske ishrane i dijetetskih vlakana u regulaciji telesne težine. Dijetetski proizvodi namenjeni regulaciji telesne težine dizajnirani su da zamene obroke i nude opcije za pojedince koji žele da redukuju telesnu masu. Pojavljuju se personalizovani pristupi ishrani koji se fokusiraju na individualne potrebe, genetske faktore i sastav crevne mikrobiote kako bi se optimizovali zdravstveni ishodi. Iako personalizovana ishrana ima sve veću primenu u nutritivnoj terapiji, potrebna su dalja istraživanja kako bi se bolje razumela njena efikasnost kod pacijenata sa gojaznošću.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd, Univerzitet u Beogradu - Farmaceutski fakultet",
journal = "Arhiv za farmaciju",
title = "Dietary interventions in obesity: a narrative review, Dijetarne intervencije kod gojaznosti: pregledni rad",
volume = "74",
number = "3",
pages = "281-297",
doi = "10.5937/arhfarm74-50457"
}
Dudašova Petrovičova, O., Đuričić, I., Ivanović, N., Dabetić, N., Dodevska, M.,& Ilić, T.. (2024). Dietary interventions in obesity: a narrative review. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 74(3), 281-297.
https://doi.org/10.5937/arhfarm74-50457
Dudašova Petrovičova O, Đuričić I, Ivanović N, Dabetić N, Dodevska M, Ilić T. Dietary interventions in obesity: a narrative review. in Arhiv za farmaciju. 2024;74(3):281-297.
doi:10.5937/arhfarm74-50457 .
Dudašova Petrovičova, Olina, Đuričić, Ivana, Ivanović, Nevena, Dabetić, Nevena, Dodevska, Margarita, Ilić, Tijana, "Dietary interventions in obesity: a narrative review" in Arhiv za farmaciju, 74, no. 3 (2024):281-297,
https://doi.org/10.5937/arhfarm74-50457 . .

Beneficial effects of a new probiotic formulation on adipocytokines, appetite-regulating hormones, and metabolic parameters in obese women

Okuka, Nina; Milinković, Neda; Veličković, Ksenija; Polovina, Snežana; Šumarac-Dumanović, Mirjana; Minić, Rajna; Korčok, Davor; Đorđević, Brižita; Ivanović, Nevena

(Royal Society of Chemistry, 2024)

TY  - JOUR
AU  - Okuka, Nina
AU  - Milinković, Neda
AU  - Veličković, Ksenija
AU  - Polovina, Snežana
AU  - Šumarac-Dumanović, Mirjana
AU  - Minić, Rajna
AU  - Korčok, Davor
AU  - Đorđević, Brižita
AU  - Ivanović, Nevena
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5699
AB  - Obesity is often accompanied by low-grade chronic inflammation and metabolic syndrome. It has been established that microbiota influences many physiological processes, including the development of obesity, and dysbiosis has been observed in obese individuals. In this study, we aimed to evaluate the impact of a new probiotic formulation, containing two probiotic strains and the bioactive compound octacosanol, on body weight, metabolic parameters, and concentrations of certain adipocytokines and appetite-regulating hormones in obese women. This double blind placebo-controlled supplementary intervention study included twenty-five women in the intervention group and twenty-three in the placebo group, and it lasted 12 weeks. Daily oral supplementation included 7 × 1010 CFU of Lactiplantibacillus plantarum 299v (DSM9843), 5 × 109 CFU of Saccharomyces cerevisiae var. boulardii (DBVPG6763), and 40 mg of octacosanol or placebo. Body weight, metabolic parameters, adipocytokines, and appetite-regulating hormones were assessed before (T0) and after the intervention (T1). After the intervention, significantly lower median concentrations of CRP (p = 0.005) and IL-6 (p = 0.012) were measured in the intervention group than the baseline, while the median concentrations of ghrelin (p = 0.026) and HDL-cholesterol (p = 0.03) were significantly increased. The intervention group had lower CRP levels (p = 0.023) and higher ghrelin levels (p = 0.006) than the placebo group. Significant changes in BMI between groups were not observed. In summary, although the new probiotic formulation showed beneficial effects on IL-6, CRP, HDL, and ghrelin levels, its potential effects on regulating triglyceride, insulin, and glucose levels require further studies before the novel dietary intervention could be considered a useful adjuvant therapy and an effective strategy for the management of obesity and obesity-associated comorbidities. © 2024 The Royal Society of Chemistry.
PB  - Royal Society of Chemistry
T2  - Food and Function
T1  - Beneficial effects of a new probiotic formulation on adipocytokines, appetite-regulating hormones, and metabolic parameters in obese women
VL  - 15
IS  - 14
SP  - 7658
EP  - 7668
DO  - 10.1039/d4fo01269k
ER  - 
@article{
author = "Okuka, Nina and Milinković, Neda and Veličković, Ksenija and Polovina, Snežana and Šumarac-Dumanović, Mirjana and Minić, Rajna and Korčok, Davor and Đorđević, Brižita and Ivanović, Nevena",
year = "2024",
abstract = "Obesity is often accompanied by low-grade chronic inflammation and metabolic syndrome. It has been established that microbiota influences many physiological processes, including the development of obesity, and dysbiosis has been observed in obese individuals. In this study, we aimed to evaluate the impact of a new probiotic formulation, containing two probiotic strains and the bioactive compound octacosanol, on body weight, metabolic parameters, and concentrations of certain adipocytokines and appetite-regulating hormones in obese women. This double blind placebo-controlled supplementary intervention study included twenty-five women in the intervention group and twenty-three in the placebo group, and it lasted 12 weeks. Daily oral supplementation included 7 × 1010 CFU of Lactiplantibacillus plantarum 299v (DSM9843), 5 × 109 CFU of Saccharomyces cerevisiae var. boulardii (DBVPG6763), and 40 mg of octacosanol or placebo. Body weight, metabolic parameters, adipocytokines, and appetite-regulating hormones were assessed before (T0) and after the intervention (T1). After the intervention, significantly lower median concentrations of CRP (p = 0.005) and IL-6 (p = 0.012) were measured in the intervention group than the baseline, while the median concentrations of ghrelin (p = 0.026) and HDL-cholesterol (p = 0.03) were significantly increased. The intervention group had lower CRP levels (p = 0.023) and higher ghrelin levels (p = 0.006) than the placebo group. Significant changes in BMI between groups were not observed. In summary, although the new probiotic formulation showed beneficial effects on IL-6, CRP, HDL, and ghrelin levels, its potential effects on regulating triglyceride, insulin, and glucose levels require further studies before the novel dietary intervention could be considered a useful adjuvant therapy and an effective strategy for the management of obesity and obesity-associated comorbidities. © 2024 The Royal Society of Chemistry.",
publisher = "Royal Society of Chemistry",
journal = "Food and Function",
title = "Beneficial effects of a new probiotic formulation on adipocytokines, appetite-regulating hormones, and metabolic parameters in obese women",
volume = "15",
number = "14",
pages = "7658-7668",
doi = "10.1039/d4fo01269k"
}
Okuka, N., Milinković, N., Veličković, K., Polovina, S., Šumarac-Dumanović, M., Minić, R., Korčok, D., Đorđević, B.,& Ivanović, N.. (2024). Beneficial effects of a new probiotic formulation on adipocytokines, appetite-regulating hormones, and metabolic parameters in obese women. in Food and Function
Royal Society of Chemistry., 15(14), 7658-7668.
https://doi.org/10.1039/d4fo01269k
Okuka N, Milinković N, Veličković K, Polovina S, Šumarac-Dumanović M, Minić R, Korčok D, Đorđević B, Ivanović N. Beneficial effects of a new probiotic formulation on adipocytokines, appetite-regulating hormones, and metabolic parameters in obese women. in Food and Function. 2024;15(14):7658-7668.
doi:10.1039/d4fo01269k .
Okuka, Nina, Milinković, Neda, Veličković, Ksenija, Polovina, Snežana, Šumarac-Dumanović, Mirjana, Minić, Rajna, Korčok, Davor, Đorđević, Brižita, Ivanović, Nevena, "Beneficial effects of a new probiotic formulation on adipocytokines, appetite-regulating hormones, and metabolic parameters in obese women" in Food and Function, 15, no. 14 (2024):7658-7668,
https://doi.org/10.1039/d4fo01269k . .
1

Unripe walnut friut extracts – phenolic content and antioxidative activity

Ivanović, Nevena; Kukić-Marković, Jelena; Lukić, Maša; Janošević-Ležaić, Aleksandra; Dodevska, Margarita

(University of Belgrade - Faculty of Agriculture, 6 Nemanjina street, 11080 Zemun - Belgrade, 2024)

TY  - CONF
AU  - Ivanović, Nevena
AU  - Kukić-Marković, Jelena
AU  - Lukić, Maša
AU  - Janošević-Ležaić, Aleksandra
AU  - Dodevska, Margarita
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5696
AB  - Walnut (Juglans regia L., Juglandaceae) is a deciduous tree mainly known for its delicious and
nutritious nuts, a source for dermatocosmetic and phytoterapeutic products as well as a raw material
in wood industry. It grows wild or semi-wild from the Southeast Europe to the Japan, but is also an
important plantation-grown species. Walnut leaves are also used in folk medicine as an astringent,
antiseptic or to stimulate the secretion of bile and for preparation of traditional herbal medicines for
wound treatment. Unripe walnut fruits are used to prepare liqueur, which is also attributed with
medicinal properties.
In this study, six samples of unripe walnut fruits were randomly collected from different region of
Serbia in period May-June 2022. The samples were extracted with 70% ethanol following
traditional procedure for liqueur preparation: maceration for 40 days on direct sunlight. After this
period, extracts were filtered in dark bottles and kept at 4 °C. The content of total phenolics,
flavonoids and juglon, as well as their anti-DPPH• activity, were determined
spectrophotometrically. The content of total phenolics and flavonoids in investigated samples was
ranged 0.78-2.08 mg gallic acid equivalents/ml and 1.10-1.62 mg catechin equivalents/ml,
respectively. Both parameters showed clear decrease with fruit maturity: the highest values were in
samples of unripe fruits collected in May. In all samples juglon was determined in very low
quantities (up to 18.45 μg/ml). Antioxidant activity of analysed samples was also very pronounced
(over 80% of DPPH• inhibition).
Obtained results pointed out ethanolic extracts of unripe walnut fruits as a rich and valuable sources
of phenolics, with high antioxidative and thus potentially high biological activity.
PB  - University of Belgrade - Faculty of Agriculture, 6 Nemanjina street, 11080 Zemun - Belgrade
C3  - UNIFood2024 Conference, Belgrade, June 28-29, 2024, Book of Abstracts
T1  - Unripe walnut friut extracts – phenolic content and antioxidative activity
SP  - 138
EP  - 138
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5696
ER  - 
@conference{
author = "Ivanović, Nevena and Kukić-Marković, Jelena and Lukić, Maša and Janošević-Ležaić, Aleksandra and Dodevska, Margarita",
year = "2024",
abstract = "Walnut (Juglans regia L., Juglandaceae) is a deciduous tree mainly known for its delicious and
nutritious nuts, a source for dermatocosmetic and phytoterapeutic products as well as a raw material
in wood industry. It grows wild or semi-wild from the Southeast Europe to the Japan, but is also an
important plantation-grown species. Walnut leaves are also used in folk medicine as an astringent,
antiseptic or to stimulate the secretion of bile and for preparation of traditional herbal medicines for
wound treatment. Unripe walnut fruits are used to prepare liqueur, which is also attributed with
medicinal properties.
In this study, six samples of unripe walnut fruits were randomly collected from different region of
Serbia in period May-June 2022. The samples were extracted with 70% ethanol following
traditional procedure for liqueur preparation: maceration for 40 days on direct sunlight. After this
period, extracts were filtered in dark bottles and kept at 4 °C. The content of total phenolics,
flavonoids and juglon, as well as their anti-DPPH• activity, were determined
spectrophotometrically. The content of total phenolics and flavonoids in investigated samples was
ranged 0.78-2.08 mg gallic acid equivalents/ml and 1.10-1.62 mg catechin equivalents/ml,
respectively. Both parameters showed clear decrease with fruit maturity: the highest values were in
samples of unripe fruits collected in May. In all samples juglon was determined in very low
quantities (up to 18.45 μg/ml). Antioxidant activity of analysed samples was also very pronounced
(over 80% of DPPH• inhibition).
Obtained results pointed out ethanolic extracts of unripe walnut fruits as a rich and valuable sources
of phenolics, with high antioxidative and thus potentially high biological activity.",
publisher = "University of Belgrade - Faculty of Agriculture, 6 Nemanjina street, 11080 Zemun - Belgrade",
journal = "UNIFood2024 Conference, Belgrade, June 28-29, 2024, Book of Abstracts",
title = "Unripe walnut friut extracts – phenolic content and antioxidative activity",
pages = "138-138",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5696"
}
Ivanović, N., Kukić-Marković, J., Lukić, M., Janošević-Ležaić, A.,& Dodevska, M.. (2024). Unripe walnut friut extracts – phenolic content and antioxidative activity. in UNIFood2024 Conference, Belgrade, June 28-29, 2024, Book of Abstracts
University of Belgrade - Faculty of Agriculture, 6 Nemanjina street, 11080 Zemun - Belgrade., 138-138.
https://hdl.handle.net/21.15107/rcub_farfar_5696
Ivanović N, Kukić-Marković J, Lukić M, Janošević-Ležaić A, Dodevska M. Unripe walnut friut extracts – phenolic content and antioxidative activity. in UNIFood2024 Conference, Belgrade, June 28-29, 2024, Book of Abstracts. 2024;:138-138.
https://hdl.handle.net/21.15107/rcub_farfar_5696 .
Ivanović, Nevena, Kukić-Marković, Jelena, Lukić, Maša, Janošević-Ležaić, Aleksandra, Dodevska, Margarita, "Unripe walnut friut extracts – phenolic content and antioxidative activity" in UNIFood2024 Conference, Belgrade, June 28-29, 2024, Book of Abstracts (2024):138-138,
https://hdl.handle.net/21.15107/rcub_farfar_5696 .

Health sciences students' perspectives on online teaching and learning: Extending the implications beyond the COVID-19 pandemic

Kovačević, Milena; Ivanović, Nevena; Protić, Ana; Milenković, Danijela; Mandinić, Zoran; Puzović, Dragana; Bajčetić, Miloš; Popadić, Dušan; Parojčić, Jelena; Malenović, Anđelija

(John Wiley & Sons Ltd, 2024)

TY  - JOUR
AU  - Kovačević, Milena
AU  - Ivanović, Nevena
AU  - Protić, Ana
AU  - Milenković, Danijela
AU  - Mandinić, Zoran
AU  - Puzović, Dragana
AU  - Bajčetić, Miloš
AU  - Popadić, Dušan
AU  - Parojčić, Jelena
AU  - Malenović, Anđelija
PY  - 2024
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5596
AB  - Digital transformation in education and relevant calls for action are recognised global priorities aimed to support education and training in the digital age. The experiences from the emergency remote teaching during the COVID-19 pandemic and recent research findings reveal relevant advantages, challenges, as well as different students and teaching staff perspectives which should be carefully considered and integrated into institutional strategies and policies to improve and enrich students’ learning experience. The present study aimed to explore health sciences students' perspectives on online teaching and learning (T&L) in four domains—Satisfaction, Motivation, Interaction and Challenges, and to identify the preferred T&L models or tools. A total of 1,041 responses were collected, including 476 dental medicine (45.7%), 399 pharmacy (38.3%), and 166 medical students (15.9%). Overall Satisfaction was quite high (4.0 ± 1.2; out of 5), followed by satisfactory Interaction (3.4 ± 1.4), whereas Motivation was quite low on average (3.0 ± 1.5). Challenges in online T&L were not markedly expressed (3.0 ± 1.6). The majority of students (46.6%) opted for the blended model as the preferred T&L model. Moodle lessons were perceived as the most useful online T&L tool (45.5% of students), followed by video materials (32.2%). Other T&L tools which require more active student's role, such as short test/quiz, and group or team assignment were declared as less favourable. The findings from the current study may contribute to raising the awareness of academic staff and higher institutions management about the student attitudes and needs related to online T&L and inform institutional planning, decision-making and policy development.
PB  - John Wiley & Sons Ltd
T2  - European Journal of Education
T1  - Health sciences students' perspectives on online teaching and learning: Extending the implications beyond the COVID-19 pandemic
DO  - 10.1111/ejed.12660
ER  - 
@article{
author = "Kovačević, Milena and Ivanović, Nevena and Protić, Ana and Milenković, Danijela and Mandinić, Zoran and Puzović, Dragana and Bajčetić, Miloš and Popadić, Dušan and Parojčić, Jelena and Malenović, Anđelija",
year = "2024",
abstract = "Digital transformation in education and relevant calls for action are recognised global priorities aimed to support education and training in the digital age. The experiences from the emergency remote teaching during the COVID-19 pandemic and recent research findings reveal relevant advantages, challenges, as well as different students and teaching staff perspectives which should be carefully considered and integrated into institutional strategies and policies to improve and enrich students’ learning experience. The present study aimed to explore health sciences students' perspectives on online teaching and learning (T&L) in four domains—Satisfaction, Motivation, Interaction and Challenges, and to identify the preferred T&L models or tools. A total of 1,041 responses were collected, including 476 dental medicine (45.7%), 399 pharmacy (38.3%), and 166 medical students (15.9%). Overall Satisfaction was quite high (4.0 ± 1.2; out of 5), followed by satisfactory Interaction (3.4 ± 1.4), whereas Motivation was quite low on average (3.0 ± 1.5). Challenges in online T&L were not markedly expressed (3.0 ± 1.6). The majority of students (46.6%) opted for the blended model as the preferred T&L model. Moodle lessons were perceived as the most useful online T&L tool (45.5% of students), followed by video materials (32.2%). Other T&L tools which require more active student's role, such as short test/quiz, and group or team assignment were declared as less favourable. The findings from the current study may contribute to raising the awareness of academic staff and higher institutions management about the student attitudes and needs related to online T&L and inform institutional planning, decision-making and policy development.",
publisher = "John Wiley & Sons Ltd",
journal = "European Journal of Education",
title = "Health sciences students' perspectives on online teaching and learning: Extending the implications beyond the COVID-19 pandemic",
doi = "10.1111/ejed.12660"
}
Kovačević, M., Ivanović, N., Protić, A., Milenković, D., Mandinić, Z., Puzović, D., Bajčetić, M., Popadić, D., Parojčić, J.,& Malenović, A.. (2024). Health sciences students' perspectives on online teaching and learning: Extending the implications beyond the COVID-19 pandemic. in European Journal of Education
John Wiley & Sons Ltd..
https://doi.org/10.1111/ejed.12660
Kovačević M, Ivanović N, Protić A, Milenković D, Mandinić Z, Puzović D, Bajčetić M, Popadić D, Parojčić J, Malenović A. Health sciences students' perspectives on online teaching and learning: Extending the implications beyond the COVID-19 pandemic. in European Journal of Education. 2024;.
doi:10.1111/ejed.12660 .
Kovačević, Milena, Ivanović, Nevena, Protić, Ana, Milenković, Danijela, Mandinić, Zoran, Puzović, Dragana, Bajčetić, Miloš, Popadić, Dušan, Parojčić, Jelena, Malenović, Anđelija, "Health sciences students' perspectives on online teaching and learning: Extending the implications beyond the COVID-19 pandemic" in European Journal of Education (2024),
https://doi.org/10.1111/ejed.12660 . .

Phenolics and Flavonoid Content in Selected Seeds from the Serbian Market

Dodevska, Margarita; Ivanović, Nevena; Kukić-Marković, Jelena; Jovanović, Verica

(MDPI, 2023)

TY  - CONF
AU  - Dodevska, Margarita
AU  - Ivanović, Nevena
AU  - Kukić-Marković, Jelena
AU  - Jovanović, Verica
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5547
AB  - Objectives: Edible seeds are usually consumed as common food ingredients. They are
considered to have a rich nutrient profile, containing different macro and micronutrients, as well
as some biologically active compounds with positive health effects, such as different phenolics.
The aim of this work was to determine total phenolics (TPC) and total flavonoid content (TFC)
in selected commercial seeds samples from the Serbian market. Methods: Samples of nine seeds
were investigated (sesame and black sesame, raw and roasted sunflower, raw and roasted pumpkin,
hemp, chia and linseed). The samples of native seeds and those defatted using dichloromethane
(maceration and Soxhlet extraction) were extracted with 80% methanol. Obtained hydro-methanol
extracts were dried and further analysed using spectrophotometric methods: TPC was determined
using Folin–Ciocalteu (FC) reagent and expressed as gallic acid equivalents (GAE), while TFC was
measured based on the reaction between flavonoids and aluminium chloride and expressed as
catechin equivalents (KE). Results: In general, hydro-methanol extracts of seed samples defatted
using Soxhlet extraction had the highest TPC and TFC contents. TPC values ranged from 9.47 g
GAE/mg (raw pumpkin seed) to over 170 g GAE/mg (raw sunflower seeds). As for TFC, the
highest amount was measured in extracts of defatted raw sunflower seeds (over 150 g KE/mg),
while roasted pumpkin and hemp seeds’ extracts were practically devoid of flavonoids. Conclusion:
Our results confirmed the fact that certain defatted seeds, which are usually considered as waste
products in oil production, could be considered as valuable sources of certain secondary plant
metabolites, implicating further investigations on their composition and potential in the development
of functional foods.
PB  - MDPI
C3  - Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November
T1  - Phenolics and Flavonoid Content in Selected Seeds from the Serbian Market
VL  - 91
IS  - 1
SP  - 374
EP  - 374
DO  - 10.3390/proceedings2023091374
ER  - 
@conference{
author = "Dodevska, Margarita and Ivanović, Nevena and Kukić-Marković, Jelena and Jovanović, Verica",
year = "2023",
abstract = "Objectives: Edible seeds are usually consumed as common food ingredients. They are
considered to have a rich nutrient profile, containing different macro and micronutrients, as well
as some biologically active compounds with positive health effects, such as different phenolics.
The aim of this work was to determine total phenolics (TPC) and total flavonoid content (TFC)
in selected commercial seeds samples from the Serbian market. Methods: Samples of nine seeds
were investigated (sesame and black sesame, raw and roasted sunflower, raw and roasted pumpkin,
hemp, chia and linseed). The samples of native seeds and those defatted using dichloromethane
(maceration and Soxhlet extraction) were extracted with 80% methanol. Obtained hydro-methanol
extracts were dried and further analysed using spectrophotometric methods: TPC was determined
using Folin–Ciocalteu (FC) reagent and expressed as gallic acid equivalents (GAE), while TFC was
measured based on the reaction between flavonoids and aluminium chloride and expressed as
catechin equivalents (KE). Results: In general, hydro-methanol extracts of seed samples defatted
using Soxhlet extraction had the highest TPC and TFC contents. TPC values ranged from 9.47 g
GAE/mg (raw pumpkin seed) to over 170 g GAE/mg (raw sunflower seeds). As for TFC, the
highest amount was measured in extracts of defatted raw sunflower seeds (over 150 g KE/mg),
while roasted pumpkin and hemp seeds’ extracts were practically devoid of flavonoids. Conclusion:
Our results confirmed the fact that certain defatted seeds, which are usually considered as waste
products in oil production, could be considered as valuable sources of certain secondary plant
metabolites, implicating further investigations on their composition and potential in the development
of functional foods.",
publisher = "MDPI",
journal = "Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November",
title = "Phenolics and Flavonoid Content in Selected Seeds from the Serbian Market",
volume = "91",
number = "1",
pages = "374-374",
doi = "10.3390/proceedings2023091374"
}
Dodevska, M., Ivanović, N., Kukić-Marković, J.,& Jovanović, V.. (2023). Phenolics and Flavonoid Content in Selected Seeds from the Serbian Market. in Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November
MDPI., 91(1), 374-374.
https://doi.org/10.3390/proceedings2023091374
Dodevska M, Ivanović N, Kukić-Marković J, Jovanović V. Phenolics and Flavonoid Content in Selected Seeds from the Serbian Market. in Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November. 2023;91(1):374-374.
doi:10.3390/proceedings2023091374 .
Dodevska, Margarita, Ivanović, Nevena, Kukić-Marković, Jelena, Jovanović, Verica, "Phenolics and Flavonoid Content in Selected Seeds from the Serbian Market" in Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November, 91, no. 1 (2023):374-374,
https://doi.org/10.3390/proceedings2023091374 . .

Dietary Intakes of Sugar in the Student Population from Fruits and Beverages

Dodevska, Margarita; Kukić-Marković, Jelena; Ivanović, Nevena; Perišić, Tamara; Jovanović, Verica

(MDPI, 2023)

TY  - CONF
AU  - Dodevska, Margarita
AU  - Kukić-Marković, Jelena
AU  - Ivanović, Nevena
AU  - Perišić, Tamara
AU  - Jovanović, Verica
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5546
AB  - Objectives: A healthy diet includes the intake of sugar (up to 5%) from natural sources,
because added sugars increase energy but not nutritional value, and are associated with an increased
risk of developing obesity, cardiovascular diseases and hypertension. Sugars present in fresh fruit,
fruit juices and nectars, refreshing soft drinks and alcoholic drinks usually represent half of the
total sugar intake. The aim of this study was to analyze, through surveys, the habits of the student
population regarding the consumption of food from the sources mentioned and to determine the
amount of sugar consumed. Methods: 123 students (male: 36, female: 87), aged 19 to 32, participated
in this research. Data collection was voluntary and anonymous, and the survey was conducted
using an electronic questionnaire during February 2023. The data on the sugar content of the foods
mentioned were taken from the declarations of the products that are available for free sale. Results:
Based on the processed results from the completed questionnaires, it was concluded that from the
sources mentioned, sugar is represented by 3.7% in relation to the total energy intake, and added
sugar by 2.4% if 2000 kcal/day is consumed. In relation to the representation of carbohydrates of
60% in relation to the total energy intake, the sugar content from the tested sources accounted for
6.3%, and added sugar accounted for 4.0%. Students reported that they most often do not consume
hard liquor (88% of respondents), and that they eat a teaspoon of honey/sugar once a day (14% of
respondents). Conclusion: Although the obtained results are very acceptable and encouraging, it
is necessary to act additionally in terms of increasing awareness of the reduced intake of products
with added sugars and their replacement with those that contain biologically active compounds in
addition to natural sugar composition.
PB  - MDPI
C3  - Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November
T1  - Dietary Intakes of Sugar in the Student Population from Fruits and Beverages
VL  - 91
IS  - 1
SP  - 215
EP  - 215
DO  - 10.3390/proceedings2023091215
ER  - 
@conference{
author = "Dodevska, Margarita and Kukić-Marković, Jelena and Ivanović, Nevena and Perišić, Tamara and Jovanović, Verica",
year = "2023",
abstract = "Objectives: A healthy diet includes the intake of sugar (up to 5%) from natural sources,
because added sugars increase energy but not nutritional value, and are associated with an increased
risk of developing obesity, cardiovascular diseases and hypertension. Sugars present in fresh fruit,
fruit juices and nectars, refreshing soft drinks and alcoholic drinks usually represent half of the
total sugar intake. The aim of this study was to analyze, through surveys, the habits of the student
population regarding the consumption of food from the sources mentioned and to determine the
amount of sugar consumed. Methods: 123 students (male: 36, female: 87), aged 19 to 32, participated
in this research. Data collection was voluntary and anonymous, and the survey was conducted
using an electronic questionnaire during February 2023. The data on the sugar content of the foods
mentioned were taken from the declarations of the products that are available for free sale. Results:
Based on the processed results from the completed questionnaires, it was concluded that from the
sources mentioned, sugar is represented by 3.7% in relation to the total energy intake, and added
sugar by 2.4% if 2000 kcal/day is consumed. In relation to the representation of carbohydrates of
60% in relation to the total energy intake, the sugar content from the tested sources accounted for
6.3%, and added sugar accounted for 4.0%. Students reported that they most often do not consume
hard liquor (88% of respondents), and that they eat a teaspoon of honey/sugar once a day (14% of
respondents). Conclusion: Although the obtained results are very acceptable and encouraging, it
is necessary to act additionally in terms of increasing awareness of the reduced intake of products
with added sugars and their replacement with those that contain biologically active compounds in
addition to natural sugar composition.",
publisher = "MDPI",
journal = "Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November",
title = "Dietary Intakes of Sugar in the Student Population from Fruits and Beverages",
volume = "91",
number = "1",
pages = "215-215",
doi = "10.3390/proceedings2023091215"
}
Dodevska, M., Kukić-Marković, J., Ivanović, N., Perišić, T.,& Jovanović, V.. (2023). Dietary Intakes of Sugar in the Student Population from Fruits and Beverages. in Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November
MDPI., 91(1), 215-215.
https://doi.org/10.3390/proceedings2023091215
Dodevska M, Kukić-Marković J, Ivanović N, Perišić T, Jovanović V. Dietary Intakes of Sugar in the Student Population from Fruits and Beverages. in Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November. 2023;91(1):215-215.
doi:10.3390/proceedings2023091215 .
Dodevska, Margarita, Kukić-Marković, Jelena, Ivanović, Nevena, Perišić, Tamara, Jovanović, Verica, "Dietary Intakes of Sugar in the Student Population from Fruits and Beverages" in Proceedings, The 14th European Nutrition Conference FENS, Serbia, Belgrade, 14–17 November, 91, no. 1 (2023):215-215,
https://doi.org/10.3390/proceedings2023091215 . .

Knowledge, attitudes and dietary practices of health proffesionals regarding sustainable diet

Ivanović, Nevena; Zeković, Milica; Kukić-Marković, Jelena; Dodevska, Margarita; Đorđević, Brižita

(International Conference of Raw Materials to Processed Foods, 2023)

TY  - CONF
AU  - Ivanović, Nevena
AU  - Zeković, Milica
AU  - Kukić-Marković, Jelena
AU  - Dodevska, Margarita
AU  - Đorđević, Brižita
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5515
AB  - Sustainable diets are defined by the Food and Agriculture Organisation of the United Nations (FAO) as “diets with low environmental impact that contribute to food and nutrition security and healthy lives for present and future generations”. ...
PB  - International Conference of Raw Materials to Processed Foods
C3  - 3rd International Conference on Raw Materials to Processed Foods, Istanbul, Turkey, 18-19 May 2023, Procedings Book
T1  - Knowledge, attitudes and dietary practices of health proffesionals regarding sustainable diet
SP  - 115
EP  - 115
UR  - https://hdl.handle.net/21.15107/rcub_farfar_5515
ER  - 
@conference{
author = "Ivanović, Nevena and Zeković, Milica and Kukić-Marković, Jelena and Dodevska, Margarita and Đorđević, Brižita",
year = "2023",
abstract = "Sustainable diets are defined by the Food and Agriculture Organisation of the United Nations (FAO) as “diets with low environmental impact that contribute to food and nutrition security and healthy lives for present and future generations”. ...",
publisher = "International Conference of Raw Materials to Processed Foods",
journal = "3rd International Conference on Raw Materials to Processed Foods, Istanbul, Turkey, 18-19 May 2023, Procedings Book",
title = "Knowledge, attitudes and dietary practices of health proffesionals regarding sustainable diet",
pages = "115-115",
url = "https://hdl.handle.net/21.15107/rcub_farfar_5515"
}
Ivanović, N., Zeković, M., Kukić-Marković, J., Dodevska, M.,& Đorđević, B.. (2023). Knowledge, attitudes and dietary practices of health proffesionals regarding sustainable diet. in 3rd International Conference on Raw Materials to Processed Foods, Istanbul, Turkey, 18-19 May 2023, Procedings Book
International Conference of Raw Materials to Processed Foods., 115-115.
https://hdl.handle.net/21.15107/rcub_farfar_5515
Ivanović N, Zeković M, Kukić-Marković J, Dodevska M, Đorđević B. Knowledge, attitudes and dietary practices of health proffesionals regarding sustainable diet. in 3rd International Conference on Raw Materials to Processed Foods, Istanbul, Turkey, 18-19 May 2023, Procedings Book. 2023;:115-115.
https://hdl.handle.net/21.15107/rcub_farfar_5515 .
Ivanović, Nevena, Zeković, Milica, Kukić-Marković, Jelena, Dodevska, Margarita, Đorđević, Brižita, "Knowledge, attitudes and dietary practices of health proffesionals regarding sustainable diet" in 3rd International Conference on Raw Materials to Processed Foods, Istanbul, Turkey, 18-19 May 2023, Procedings Book (2023):115-115,
https://hdl.handle.net/21.15107/rcub_farfar_5515 .

Agri-food by-products as a source of sustainable ingredients for the production of functional foods and nutraceuticals

Ivanović, Nevena; Ilić, Tijana; Zrnić-Ćirić, Milica; Todorović, Vanja; Đuričić, Ivana; Dabetić, Nevena

(Savez farmaceutskih udruženja Srbije (SFUS), 2023)

TY  - JOUR
AU  - Ivanović, Nevena
AU  - Ilić, Tijana
AU  - Zrnić-Ćirić, Milica
AU  - Todorović, Vanja
AU  - Đuričić, Ivana
AU  - Dabetić, Nevena
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4979
AB  - The disposal of waste generated in the agri-food industry is one of the greatest challenges
in achieving sustainable development. Although agri-food residues are a potential source of
bioactive compounds with proven health benefits, they are largely unused and disposed of as
organic waste. The recovery of bioactive compounds from agri-food waste to obtain products
with high biological value, such as functional foods and nutraceuticals, is an idea that stems from
the concept of bioeconomy and combines environmental issues with economically viable
production. Some of the main agri-food wastes in Serbia that have the potential to be recycled
into value-added products are apple, plum, grape, tomato, and beet pomace, and oilseed cakes.
Bioactive compounds isolated from these wastes include polyphenols, fibers, essential fatty acids,
minerals, various volatiles and pigments. This article focuses on the most common food wastes
and the potential reuse of these undervalued material to produce value-added products such as
functional foods, nutraceuticals or food additives.
AB  - Odlaganje otpada koji nastaje u prehrambenoj industriji jedan je od najvećih izazova u
postizanju održivog razvoja. Iako su nusproizvodi koji nastaju u prehrambenoj industriji
potencijalni izvor bioaktivnih jedinjenja sa dokazanim pozitivnim zdravstvenim efektima, oni se
uglavnom odlažu kao organski otpad. Iskorišćenje bioaktivnih jedinjenja iz ovih nusproizvoda u
cilju dobijanja proizvoda sa dodatom nutritivnom i biološkom vrednošću, kao što su funkcionalna
hrana i nutraceutici, ideja je koja proizilazi iz koncepta bioekonomije i kombinuje ekološki aspekt
sa ekonomski održivom proizvodnjom. Neki od glavnih nusproizvoda koji se generišu u Srbiji sa
potencijalom da se iskoriste u proizvodnji proizvoda sa dodatom vrednošću su trop jabuke, trop
šljive, komina grožđa, trop paradajza, uljane pogače i dr. Bioaktivna jedinjenja izolovana iz ovih
otpada uključuju polifenole, peptide, vlakna, esencijalne masne kiseline, minerale, različite
isparljive materije i pigmente. Ovaj članak se fokusira na najčešće otpade prehrambene industrije
i potencijalnu ponovnu upotrebu ovog još uvek neiskorišćenog otpadnog materijala za
proizvodnju proizvoda sa dodatom vrednošću kao što su funkcionalna hrana, nutraceutici ili
aditivi.
PB  - Savez farmaceutskih udruženja Srbije (SFUS)
T2  - Arhiv za farmaciju
T1  - Agri-food by-products as a source of sustainable ingredients for the production of functional foods and nutraceuticals
T1  - Nusproizvodi agro-industrije kao izvor održivih sastojaka za proizvodnju funkcionalne hrane i nutraceutika
VL  - 73
IS  - 3
SP  - 190
EP  - 204
DO  - 10.5937/arhfarm73-44481
ER  - 
@article{
author = "Ivanović, Nevena and Ilić, Tijana and Zrnić-Ćirić, Milica and Todorović, Vanja and Đuričić, Ivana and Dabetić, Nevena",
year = "2023",
abstract = "The disposal of waste generated in the agri-food industry is one of the greatest challenges
in achieving sustainable development. Although agri-food residues are a potential source of
bioactive compounds with proven health benefits, they are largely unused and disposed of as
organic waste. The recovery of bioactive compounds from agri-food waste to obtain products
with high biological value, such as functional foods and nutraceuticals, is an idea that stems from
the concept of bioeconomy and combines environmental issues with economically viable
production. Some of the main agri-food wastes in Serbia that have the potential to be recycled
into value-added products are apple, plum, grape, tomato, and beet pomace, and oilseed cakes.
Bioactive compounds isolated from these wastes include polyphenols, fibers, essential fatty acids,
minerals, various volatiles and pigments. This article focuses on the most common food wastes
and the potential reuse of these undervalued material to produce value-added products such as
functional foods, nutraceuticals or food additives., Odlaganje otpada koji nastaje u prehrambenoj industriji jedan je od najvećih izazova u
postizanju održivog razvoja. Iako su nusproizvodi koji nastaju u prehrambenoj industriji
potencijalni izvor bioaktivnih jedinjenja sa dokazanim pozitivnim zdravstvenim efektima, oni se
uglavnom odlažu kao organski otpad. Iskorišćenje bioaktivnih jedinjenja iz ovih nusproizvoda u
cilju dobijanja proizvoda sa dodatom nutritivnom i biološkom vrednošću, kao što su funkcionalna
hrana i nutraceutici, ideja je koja proizilazi iz koncepta bioekonomije i kombinuje ekološki aspekt
sa ekonomski održivom proizvodnjom. Neki od glavnih nusproizvoda koji se generišu u Srbiji sa
potencijalom da se iskoriste u proizvodnji proizvoda sa dodatom vrednošću su trop jabuke, trop
šljive, komina grožđa, trop paradajza, uljane pogače i dr. Bioaktivna jedinjenja izolovana iz ovih
otpada uključuju polifenole, peptide, vlakna, esencijalne masne kiseline, minerale, različite
isparljive materije i pigmente. Ovaj članak se fokusira na najčešće otpade prehrambene industrije
i potencijalnu ponovnu upotrebu ovog još uvek neiskorišćenog otpadnog materijala za
proizvodnju proizvoda sa dodatom vrednošću kao što su funkcionalna hrana, nutraceutici ili
aditivi.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Agri-food by-products as a source of sustainable ingredients for the production of functional foods and nutraceuticals, Nusproizvodi agro-industrije kao izvor održivih sastojaka za proizvodnju funkcionalne hrane i nutraceutika",
volume = "73",
number = "3",
pages = "190-204",
doi = "10.5937/arhfarm73-44481"
}
Ivanović, N., Ilić, T., Zrnić-Ćirić, M., Todorović, V., Đuričić, I.,& Dabetić, N.. (2023). Agri-food by-products as a source of sustainable ingredients for the production of functional foods and nutraceuticals. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije (SFUS)., 73(3), 190-204.
https://doi.org/10.5937/arhfarm73-44481
Ivanović N, Ilić T, Zrnić-Ćirić M, Todorović V, Đuričić I, Dabetić N. Agri-food by-products as a source of sustainable ingredients for the production of functional foods and nutraceuticals. in Arhiv za farmaciju. 2023;73(3):190-204.
doi:10.5937/arhfarm73-44481 .
Ivanović, Nevena, Ilić, Tijana, Zrnić-Ćirić, Milica, Todorović, Vanja, Đuričić, Ivana, Dabetić, Nevena, "Agri-food by-products as a source of sustainable ingredients for the production of functional foods and nutraceuticals" in Arhiv za farmaciju, 73, no. 3 (2023):190-204,
https://doi.org/10.5937/arhfarm73-44481 . .
3

Epigenetic Aspects of a New Probiotic Concept—A Pilot Study

Okuka, Nina; Schuh, Verena; Krammer, Ulrike; Polovina, Snežana; Šumarac-Dumanović, Mirjana; Milinković, Neda; Veličković, Ksenija; Đorđević, Brižita; Haslberger, Alexander; Ivanović, Nevena

(MDPI, 2023)

TY  - JOUR
AU  - Okuka, Nina
AU  - Schuh, Verena
AU  - Krammer, Ulrike
AU  - Polovina, Snežana
AU  - Šumarac-Dumanović, Mirjana
AU  - Milinković, Neda
AU  - Veličković, Ksenija
AU  - Đorđević, Brižita
AU  - Haslberger, Alexander
AU  - Ivanović, Nevena
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5054
AB  - Several studies report the important role of an altered gut microbiota in the development of obesity, highlighting the potential use of probiotics in the treatment of obesity. The aim of this study is to investigate the effect of a novel probiotic approach on the expression of specific miRNAs and mRNAs associated with obesity in combination with the hypocholesterolemic octacosanol. Twenty overweight/obese women participated in a randomized, placebo-controlled, double-blind study and were randomly divided into two groups: the intervention group (daily one capsule containing Lactobacillus plantarum 299v (DSM9843), Saccharomyces cerevisiae var. boulardii, and 40 mg octacosanol; N = 12) and the placebo group (N = 8). Changes in lipid parameters and expression of miRNAs and mRNAs were assessed before (T0) and after the 12-week intervention (T1). After the intervention, the expression of miR-155-5p (9.38 ± 0.85 vs. 8.38 ± 1.06, p = 0.05) and miR-24-3p (3.42 ± 0.38 vs. 2.71 ± 0.97, p = 0.031) showed significant decreases in the intervention group when compared to the control group. At T1, the expression of miR-155-5p (8.69 ± 1.31 vs. 9.3 ± 0.85, p = 0.04), miR-125b-5p (5.41 ± 1.18 vs. 5.99 ± 1.36, p = 0.049), and TNF-α (10.24 ± 1.66 vs. 11.36 ± 1.12, p = 0.009) were significantly decreased in the intervention group. No changes in lipids and anthropometric parameters were observed. The novel probiotic approach had a positive effect on regulating the expression of certain miRNAs and mRNAs important for regulating inflammation and adipogenesis, which are essential for obesity onset and control.
PB  - MDPI
T2  - Life
T1  - Epigenetic Aspects of a New Probiotic Concept—A Pilot Study
VL  - 13
IS  - 9
DO  - 10.3390/life13091912
ER  - 
@article{
author = "Okuka, Nina and Schuh, Verena and Krammer, Ulrike and Polovina, Snežana and Šumarac-Dumanović, Mirjana and Milinković, Neda and Veličković, Ksenija and Đorđević, Brižita and Haslberger, Alexander and Ivanović, Nevena",
year = "2023",
abstract = "Several studies report the important role of an altered gut microbiota in the development of obesity, highlighting the potential use of probiotics in the treatment of obesity. The aim of this study is to investigate the effect of a novel probiotic approach on the expression of specific miRNAs and mRNAs associated with obesity in combination with the hypocholesterolemic octacosanol. Twenty overweight/obese women participated in a randomized, placebo-controlled, double-blind study and were randomly divided into two groups: the intervention group (daily one capsule containing Lactobacillus plantarum 299v (DSM9843), Saccharomyces cerevisiae var. boulardii, and 40 mg octacosanol; N = 12) and the placebo group (N = 8). Changes in lipid parameters and expression of miRNAs and mRNAs were assessed before (T0) and after the 12-week intervention (T1). After the intervention, the expression of miR-155-5p (9.38 ± 0.85 vs. 8.38 ± 1.06, p = 0.05) and miR-24-3p (3.42 ± 0.38 vs. 2.71 ± 0.97, p = 0.031) showed significant decreases in the intervention group when compared to the control group. At T1, the expression of miR-155-5p (8.69 ± 1.31 vs. 9.3 ± 0.85, p = 0.04), miR-125b-5p (5.41 ± 1.18 vs. 5.99 ± 1.36, p = 0.049), and TNF-α (10.24 ± 1.66 vs. 11.36 ± 1.12, p = 0.009) were significantly decreased in the intervention group. No changes in lipids and anthropometric parameters were observed. The novel probiotic approach had a positive effect on regulating the expression of certain miRNAs and mRNAs important for regulating inflammation and adipogenesis, which are essential for obesity onset and control.",
publisher = "MDPI",
journal = "Life",
title = "Epigenetic Aspects of a New Probiotic Concept—A Pilot Study",
volume = "13",
number = "9",
doi = "10.3390/life13091912"
}
Okuka, N., Schuh, V., Krammer, U., Polovina, S., Šumarac-Dumanović, M., Milinković, N., Veličković, K., Đorđević, B., Haslberger, A.,& Ivanović, N.. (2023). Epigenetic Aspects of a New Probiotic Concept—A Pilot Study. in Life
MDPI., 13(9).
https://doi.org/10.3390/life13091912
Okuka N, Schuh V, Krammer U, Polovina S, Šumarac-Dumanović M, Milinković N, Veličković K, Đorđević B, Haslberger A, Ivanović N. Epigenetic Aspects of a New Probiotic Concept—A Pilot Study. in Life. 2023;13(9).
doi:10.3390/life13091912 .
Okuka, Nina, Schuh, Verena, Krammer, Ulrike, Polovina, Snežana, Šumarac-Dumanović, Mirjana, Milinković, Neda, Veličković, Ksenija, Đorđević, Brižita, Haslberger, Alexander, Ivanović, Nevena, "Epigenetic Aspects of a New Probiotic Concept—A Pilot Study" in Life, 13, no. 9 (2023),
https://doi.org/10.3390/life13091912 . .
4
3

Analysis of vitamin content in products intended for infants and children on the Serbian market

Dodevska, Margarita; Milenković, Milan; Jovanović, Verica; Ivanović, Nevena

(Elsevier, 2023)

TY  - JOUR
AU  - Dodevska, Margarita
AU  - Milenković, Milan
AU  - Jovanović, Verica
AU  - Ivanović, Nevena
PY  - 2023
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5077
AB  - Infant formula and follow-on formula, baby food and food supplements are important sources of essential nutrients for infants and young children. It is therefore important to monitor the nutrient content of these products. The content of vitamins A, D, E, C and B group was determined in 121 samples (44 samples of infant and follow-on formulas, baby foods, foods for special medical purposes and 77 of food supplements for children. High Performance Liquid Chromatography with Fluorescence and Diode Array Detector (HPLC-FLD-DAD) methods, were used for analysis. Among these samples, almost every third sample was outside of the defined tolerance range. The biggest deviations were found for vitamins A and E. The obtained values in foods for infants and young children for vitamins A and E was 17–147 % and 24–140 % of the declared value, respectively, whereas for food supplements, they were 5–150 % and 52–205 %, respectively. The highest values for vitamin E were in instant drinks (80–203 % of the declared value). The content of vitamins D and B2 in food supplements in liquid form was 10–127 % and 11–110 % of the declared value, respectively. Considering that these foods are often the only source of essential nutrients for infants and children, these results show the need for regular monitoring of the composition of these products.
PB  - Elsevier
T2  - Journal of Food Composition and Analysis
T1  - Analysis of vitamin content in products intended for infants and children on the Serbian market
VL  - 123
DO  - 10.1016/j.jfca.2023.105633
ER  - 
@article{
author = "Dodevska, Margarita and Milenković, Milan and Jovanović, Verica and Ivanović, Nevena",
year = "2023",
abstract = "Infant formula and follow-on formula, baby food and food supplements are important sources of essential nutrients for infants and young children. It is therefore important to monitor the nutrient content of these products. The content of vitamins A, D, E, C and B group was determined in 121 samples (44 samples of infant and follow-on formulas, baby foods, foods for special medical purposes and 77 of food supplements for children. High Performance Liquid Chromatography with Fluorescence and Diode Array Detector (HPLC-FLD-DAD) methods, were used for analysis. Among these samples, almost every third sample was outside of the defined tolerance range. The biggest deviations were found for vitamins A and E. The obtained values in foods for infants and young children for vitamins A and E was 17–147 % and 24–140 % of the declared value, respectively, whereas for food supplements, they were 5–150 % and 52–205 %, respectively. The highest values for vitamin E were in instant drinks (80–203 % of the declared value). The content of vitamins D and B2 in food supplements in liquid form was 10–127 % and 11–110 % of the declared value, respectively. Considering that these foods are often the only source of essential nutrients for infants and children, these results show the need for regular monitoring of the composition of these products.",
publisher = "Elsevier",
journal = "Journal of Food Composition and Analysis",
title = "Analysis of vitamin content in products intended for infants and children on the Serbian market",
volume = "123",
doi = "10.1016/j.jfca.2023.105633"
}
Dodevska, M., Milenković, M., Jovanović, V.,& Ivanović, N.. (2023). Analysis of vitamin content in products intended for infants and children on the Serbian market. in Journal of Food Composition and Analysis
Elsevier., 123.
https://doi.org/10.1016/j.jfca.2023.105633
Dodevska M, Milenković M, Jovanović V, Ivanović N. Analysis of vitamin content in products intended for infants and children on the Serbian market. in Journal of Food Composition and Analysis. 2023;123.
doi:10.1016/j.jfca.2023.105633 .
Dodevska, Margarita, Milenković, Milan, Jovanović, Verica, Ivanović, Nevena, "Analysis of vitamin content in products intended for infants and children on the Serbian market" in Journal of Food Composition and Analysis, 123 (2023),
https://doi.org/10.1016/j.jfca.2023.105633 . .

Analysis of mineral contents of fruits of Lycium barbarum L. (Solanaceae) cultivated in Serbia

Ilić, Tijana; Kodranov, Igor; Kolašinac, Stefan; Ivanović, Nevena; Vidović, Bojana

(Savez farmaceutskih udruženja Srbije (SFUS), 2022)

TY  - CONF
AU  - Ilić, Tijana
AU  - Kodranov, Igor
AU  - Kolašinac, Stefan
AU  - Ivanović, Nevena
AU  - Vidović, Bojana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4589
AB  - Fruits of Lycium barbarum L. (Solanaceae), known as wolfberries or goji berries, have
been long used in traditional medicine and nutrition in Asian countries. However, in recent
years, they have become popular in Europe, including Serbia. However, there are limited
data on the chemical composition of goji berries cultivated in our country. This study aimed
to estimate and perform a comparative analysis of the mineral content of goji berries from
six locations in Serbia. After microwave digestion, macro- (K, Na, P, S, Mg, Ca) and
microelement (Fe, Zn, Cu, Cr, Mn, Mo) contents in analyzed samples were determined by the
optical emission spectrometry with induced coupled plasma (ICP-OES). As expected, mineral
concentrations varied significantly among goji berry samples from different locations (p <
0.05). In general, the decreasing orders of minerals in goji berries were: K > P > S > Na > Mg >
Ca > Zn > Fe > Cu > Mn > Cr > Mo. According to the Recommended Daily Allowance (RDA)
values, dried goji berries (30 g) provide a rich source of Cr and Cu, while their contribution
to the daily intake of other minerals was below 15% RDA.
AB  - Plodovi Lycium barbarum L. (Solanaceae), poznatiji kao vučje bobice ili godži, imaju
dugu istoriju upotrebe u tradicionalnoj medicini i ishrani stanovnika azijskih zemalja, a
poslednjih godina su sve popularniji u Evropi, uključujući i Srbiju. Međutim, nema mnogo
podataka o hemijskom sastavu plodova godži gajenih u našoj zemlji. Cilj ovog rada je bio da
se izvrši komparativna analiza mineralnog sastava plodova godži prikupljenih sa šest
različitih lokacija u Srbiji. Nakon prethodne mikrotalasne digestije, sadržaj makro- (K, Na, P,
S, Mg, Ca) i mikroelemenata (Fe, Zn, Cu, Cr, Mn, Mo) u ispitivanim uzorcima suvih plodova
godži, određen je primenom optičke emisione spektrometrije sa indukovano spregnutom
plazmom (ICP-OES). Kao što je i očekivano, dobijeni rezultati ukazuju na statistički značajne
razlike u sadržaju mineralnih materija u plodovima godži prikupljenih sa različitih lokacija
(p < 0,05). Generalno, mineralne materije su zastupljene po sledećem opadajućem redosledu
koncentracija: K > P > S > Na > Mg > Ca > Zn > Fe > Cu > Mn > Cr > Mo. Utvrđeni sadržaj
makro- i mikroelemenata u jednoj porciji (30 g suvih plodova godži), u odnosu na nutritivne
referentne vrednosti (NRV), ukazuje da su plodovi godži bogat izvor Cr i Cu, dok je doprinos
jedne porcije plodova godži dnevnom unosu ostalih mineralnih materija ispod 15% NRV.
PB  - Savez farmaceutskih udruženja Srbije (SFUS)
C3  - Arhiv za farmaciju
T1  - Analysis of mineral contents of fruits of Lycium barbarum L. (Solanaceae) cultivated in Serbia
T1  - Analiza sadržaja mineralnih materija u plodovima Lycium barbarum L. (Solanaceae) gajenim u Srbiji
VL  - 72
IS  - 4 suplement
SP  - S507
EP  - S508
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4589
ER  - 
@conference{
author = "Ilić, Tijana and Kodranov, Igor and Kolašinac, Stefan and Ivanović, Nevena and Vidović, Bojana",
year = "2022",
abstract = "Fruits of Lycium barbarum L. (Solanaceae), known as wolfberries or goji berries, have
been long used in traditional medicine and nutrition in Asian countries. However, in recent
years, they have become popular in Europe, including Serbia. However, there are limited
data on the chemical composition of goji berries cultivated in our country. This study aimed
to estimate and perform a comparative analysis of the mineral content of goji berries from
six locations in Serbia. After microwave digestion, macro- (K, Na, P, S, Mg, Ca) and
microelement (Fe, Zn, Cu, Cr, Mn, Mo) contents in analyzed samples were determined by the
optical emission spectrometry with induced coupled plasma (ICP-OES). As expected, mineral
concentrations varied significantly among goji berry samples from different locations (p <
0.05). In general, the decreasing orders of minerals in goji berries were: K > P > S > Na > Mg >
Ca > Zn > Fe > Cu > Mn > Cr > Mo. According to the Recommended Daily Allowance (RDA)
values, dried goji berries (30 g) provide a rich source of Cr and Cu, while their contribution
to the daily intake of other minerals was below 15% RDA., Plodovi Lycium barbarum L. (Solanaceae), poznatiji kao vučje bobice ili godži, imaju
dugu istoriju upotrebe u tradicionalnoj medicini i ishrani stanovnika azijskih zemalja, a
poslednjih godina su sve popularniji u Evropi, uključujući i Srbiju. Međutim, nema mnogo
podataka o hemijskom sastavu plodova godži gajenih u našoj zemlji. Cilj ovog rada je bio da
se izvrši komparativna analiza mineralnog sastava plodova godži prikupljenih sa šest
različitih lokacija u Srbiji. Nakon prethodne mikrotalasne digestije, sadržaj makro- (K, Na, P,
S, Mg, Ca) i mikroelemenata (Fe, Zn, Cu, Cr, Mn, Mo) u ispitivanim uzorcima suvih plodova
godži, određen je primenom optičke emisione spektrometrije sa indukovano spregnutom
plazmom (ICP-OES). Kao što je i očekivano, dobijeni rezultati ukazuju na statistički značajne
razlike u sadržaju mineralnih materija u plodovima godži prikupljenih sa različitih lokacija
(p < 0,05). Generalno, mineralne materije su zastupljene po sledećem opadajućem redosledu
koncentracija: K > P > S > Na > Mg > Ca > Zn > Fe > Cu > Mn > Cr > Mo. Utvrđeni sadržaj
makro- i mikroelemenata u jednoj porciji (30 g suvih plodova godži), u odnosu na nutritivne
referentne vrednosti (NRV), ukazuje da su plodovi godži bogat izvor Cr i Cu, dok je doprinos
jedne porcije plodova godži dnevnom unosu ostalih mineralnih materija ispod 15% NRV.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Analysis of mineral contents of fruits of Lycium barbarum L. (Solanaceae) cultivated in Serbia, Analiza sadržaja mineralnih materija u plodovima Lycium barbarum L. (Solanaceae) gajenim u Srbiji",
volume = "72",
number = "4 suplement",
pages = "S507-S508",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4589"
}
Ilić, T., Kodranov, I., Kolašinac, S., Ivanović, N.,& Vidović, B.. (2022). Analysis of mineral contents of fruits of Lycium barbarum L. (Solanaceae) cultivated in Serbia. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije (SFUS)., 72(4 suplement), S507-S508.
https://hdl.handle.net/21.15107/rcub_farfar_4589
Ilić T, Kodranov I, Kolašinac S, Ivanović N, Vidović B. Analysis of mineral contents of fruits of Lycium barbarum L. (Solanaceae) cultivated in Serbia. in Arhiv za farmaciju. 2022;72(4 suplement):S507-S508.
https://hdl.handle.net/21.15107/rcub_farfar_4589 .
Ilić, Tijana, Kodranov, Igor, Kolašinac, Stefan, Ivanović, Nevena, Vidović, Bojana, "Analysis of mineral contents of fruits of Lycium barbarum L. (Solanaceae) cultivated in Serbia" in Arhiv za farmaciju, 72, no. 4 suplement (2022):S507-S508,
https://hdl.handle.net/21.15107/rcub_farfar_4589 .

Effects of probiotic supplementation on platelet morphology in overweight/obese woman

Veličković, Ksenija; Okuka, Nina; Polovina, Snežana; Sumarac‐Dumanović, Mirjana; Ivanović, Nevena; Milinković, Neda; Đorđević, Brižita

(Savez farmaceutskih udruženja Srbije (SFUS), 2022)

TY  - CONF
AU  - Veličković, Ksenija
AU  - Okuka, Nina
AU  - Polovina, Snežana
AU  - Sumarac‐Dumanović, Mirjana
AU  - Ivanović, Nevena
AU  - Milinković, Neda
AU  - Đorđević, Brižita
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4590
AB  - Obesity could be associated with enhanced platelet (PL) function and thrombosis.
Also, changes in gut microbiota composition were observed in obese patients, and probiotics
supplementation has been shown to improve some of the obesity-associated metabolic
parameters. This study aimed to determine the possible effects of probiotic supplementation
on platelet morphology in overweight/obese premenopausal women.Twenty overweight
(BMI = 25.0-29.9 kg/m2) and obese (BMI ≥ 30.0 kg/m2) women participated in double-
blind, randomized, placebo-controlled study. They were randomly assigned to receive one
capsule daily of probiotics (7x1010 CFU Lactobacillus plantarum 299v (DSM9843), 5x109
CFU Saccharomyces cerevisiae var. boulardii and 40mg octacosanol; N=10) or placebo
(N=10) for 3 months. To determine changes in the parameters of platelet activation - the
platelet count (PC), platelet distribution width (PDW), Feret diameter, and hypogranular
appearance, blood samples were obtained for an automated hematology analyser and
peripheral smears staining. Although difference in PC was not found between groups,
supplementation with probiotics decreased PDW compared to the placebo group (p<0.05).
Regarding platelets diameter, there is an decrease in group supplemented with probiotics
compared to placebo, however, a statistical difference has not been reached. Further, the
proportion of hypogranular PL was increased in a probiotic-supplemented group compared
to the placebo group (p<0.01). In conclusion, probiotic supplementation achieved
improvements in platelets morphology and hematological indices in overweight/obese
premenopausal women.
AB  - Gojaznost je često povezana sa povećanom funkcijom krvnih pločica i trombozom.
Takođe, istraživanja ukazuju na promenjen sastav mikrobioma creva kod gojaznih osoba,
kao i da suplementacija određenim probioticima može imati pozitivan uticaj na telesnu
masu. Cilj rada je bio da se ispita uticaj suplementacije probiotskog preparata na morfološke
karakteristike krvnih pločica u randomizovanoj, dvostruko-slepoj, placebo-kontrolisanoj
studiji. U tu svrhu, regrutovano je 20 žena sa prekomernom težinom (BMI ≥ 25,0 kg/m2) koje
su podeljene u dve grupe. Prva grupa je pila dnevno jednu kapsulu probiotskog preparata
tokom tri meseca (kombinaciju soja Lactobacillus plantarum 299v (DSM9843),
Saccharomyces cerevisiae var. boulardii i 40 mg oktakozanola; N = 10), dok je druga grupa
bila placebo grupa. Određen je broj krvnih pločica, i njihova raspodela po volumenu (eng.
platelet distribution width, PDW), a zatim je posmatrana morfologija krvnih pločica i
izmeren njihov dijametar iz krvnih razmaza. Analiza je pokazala da su krvne pločice kod
gojaznih/žena sa prekomernom težinom uglavnom krupne, što je jedan od pokazatelja
njihove aktivnosti. U interventoj grupi nije zapažena promena u broju krvnih pločica, ali je
značajno smanjen PDW u poređenju sa placebo grupom (p < 0,05). Dalje, pokazano je da je
udeo hipogranularnih krvnih pločica bio povećan u poređenju sa placebo grupom (p < 0,01).
Ovi rezultati ukazuju na pozitivan efekat probiotika na morfološke karakteristike krvnih
pločica i mogućnost primene probiotika u regulaciji njihove aktivnosti u patološkim
stanjima.
PB  - Savez farmaceutskih udruženja Srbije (SFUS)
C3  - Arhiv za farmaciju
T1  - Effects of probiotic supplementation on platelet morphology in overweight/obese woman
T1  - Efekti suplementacije probiotikom na morfologiju krvnih pločica gojaznih žena i žena sa prokomernom težinom
VL  - 72
IS  - 4 suplement
SP  - S509
EP  - S510
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4590
ER  - 
@conference{
author = "Veličković, Ksenija and Okuka, Nina and Polovina, Snežana and Sumarac‐Dumanović, Mirjana and Ivanović, Nevena and Milinković, Neda and Đorđević, Brižita",
year = "2022",
abstract = "Obesity could be associated with enhanced platelet (PL) function and thrombosis.
Also, changes in gut microbiota composition were observed in obese patients, and probiotics
supplementation has been shown to improve some of the obesity-associated metabolic
parameters. This study aimed to determine the possible effects of probiotic supplementation
on platelet morphology in overweight/obese premenopausal women.Twenty overweight
(BMI = 25.0-29.9 kg/m2) and obese (BMI ≥ 30.0 kg/m2) women participated in double-
blind, randomized, placebo-controlled study. They were randomly assigned to receive one
capsule daily of probiotics (7x1010 CFU Lactobacillus plantarum 299v (DSM9843), 5x109
CFU Saccharomyces cerevisiae var. boulardii and 40mg octacosanol; N=10) or placebo
(N=10) for 3 months. To determine changes in the parameters of platelet activation - the
platelet count (PC), platelet distribution width (PDW), Feret diameter, and hypogranular
appearance, blood samples were obtained for an automated hematology analyser and
peripheral smears staining. Although difference in PC was not found between groups,
supplementation with probiotics decreased PDW compared to the placebo group (p<0.05).
Regarding platelets diameter, there is an decrease in group supplemented with probiotics
compared to placebo, however, a statistical difference has not been reached. Further, the
proportion of hypogranular PL was increased in a probiotic-supplemented group compared
to the placebo group (p<0.01). In conclusion, probiotic supplementation achieved
improvements in platelets morphology and hematological indices in overweight/obese
premenopausal women., Gojaznost je često povezana sa povećanom funkcijom krvnih pločica i trombozom.
Takođe, istraživanja ukazuju na promenjen sastav mikrobioma creva kod gojaznih osoba,
kao i da suplementacija određenim probioticima može imati pozitivan uticaj na telesnu
masu. Cilj rada je bio da se ispita uticaj suplementacije probiotskog preparata na morfološke
karakteristike krvnih pločica u randomizovanoj, dvostruko-slepoj, placebo-kontrolisanoj
studiji. U tu svrhu, regrutovano je 20 žena sa prekomernom težinom (BMI ≥ 25,0 kg/m2) koje
su podeljene u dve grupe. Prva grupa je pila dnevno jednu kapsulu probiotskog preparata
tokom tri meseca (kombinaciju soja Lactobacillus plantarum 299v (DSM9843),
Saccharomyces cerevisiae var. boulardii i 40 mg oktakozanola; N = 10), dok je druga grupa
bila placebo grupa. Određen je broj krvnih pločica, i njihova raspodela po volumenu (eng.
platelet distribution width, PDW), a zatim je posmatrana morfologija krvnih pločica i
izmeren njihov dijametar iz krvnih razmaza. Analiza je pokazala da su krvne pločice kod
gojaznih/žena sa prekomernom težinom uglavnom krupne, što je jedan od pokazatelja
njihove aktivnosti. U interventoj grupi nije zapažena promena u broju krvnih pločica, ali je
značajno smanjen PDW u poređenju sa placebo grupom (p < 0,05). Dalje, pokazano je da je
udeo hipogranularnih krvnih pločica bio povećan u poređenju sa placebo grupom (p < 0,01).
Ovi rezultati ukazuju na pozitivan efekat probiotika na morfološke karakteristike krvnih
pločica i mogućnost primene probiotika u regulaciji njihove aktivnosti u patološkim
stanjima.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Effects of probiotic supplementation on platelet morphology in overweight/obese woman, Efekti suplementacije probiotikom na morfologiju krvnih pločica gojaznih žena i žena sa prokomernom težinom",
volume = "72",
number = "4 suplement",
pages = "S509-S510",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4590"
}
Veličković, K., Okuka, N., Polovina, S., Sumarac‐Dumanović, M., Ivanović, N., Milinković, N.,& Đorđević, B.. (2022). Effects of probiotic supplementation on platelet morphology in overweight/obese woman. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije (SFUS)., 72(4 suplement), S509-S510.
https://hdl.handle.net/21.15107/rcub_farfar_4590
Veličković K, Okuka N, Polovina S, Sumarac‐Dumanović M, Ivanović N, Milinković N, Đorđević B. Effects of probiotic supplementation on platelet morphology in overweight/obese woman. in Arhiv za farmaciju. 2022;72(4 suplement):S509-S510.
https://hdl.handle.net/21.15107/rcub_farfar_4590 .
Veličković, Ksenija, Okuka, Nina, Polovina, Snežana, Sumarac‐Dumanović, Mirjana, Ivanović, Nevena, Milinković, Neda, Đorđević, Brižita, "Effects of probiotic supplementation on platelet morphology in overweight/obese woman" in Arhiv za farmaciju, 72, no. 4 suplement (2022):S509-S510,
https://hdl.handle.net/21.15107/rcub_farfar_4590 .

Dietary factors and thyroid dysfunction

Đuričić, Ivana; Todorović, Vanja; Dabetić, Nevena; Zrnić-Ćirić, Milica; Ivanović, Nevena; Vidović, Bojana

(Pharmaceutical Association of Serbia, 2022)

TY  - JOUR
AU  - Đuričić, Ivana
AU  - Todorović, Vanja
AU  - Dabetić, Nevena
AU  - Zrnić-Ćirić, Milica
AU  - Ivanović, Nevena
AU  - Vidović, Bojana
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4404
AB  - Besides iodine deficiency, autoimmune Hashimoto thyroiditis is the leading cause of
hypothyroidism globally, characterized by the increased titer of thyroid autoantibodies and
destruction of thyroid cells. Graves' disease is the most common etiology of hyperthyroidism
worldwide. Patients with thyroid dysfunction often require dietary modifications. Popular
interventions include supplementation with certain vitamins and minerals, as well as trace
elements such as iodine and selenium. The intake of food containing goitrogens should be limited.
Goitrogens are substances of plant origin that interfere with the production of thyroid hormones,
increasing the risk for goiter and hypothyroidism. The primary dietary sources of goitrogens are
cruciferous vegetables, soy products, starchy plants, and some fruits. Beyond essential nutrients,
there has been an increasing interest in using specific nutraceuticals, including myoinositol, L-
carnitine, melatonin, and resveratrol, as potential preventive and therapeutic agents in thyroid
diseases. Even though current evidence promotes some beneficial outcomes of these
nutraceuticals, further investigations are needed to clarify dose-dependent effects, duration of
supplementation, combination in different clinical settings, and the exact mechanism of their
action in thyroid disorders.
AB  - Pored nedostatka joda, najčešća etiologija hipotireoze u razvijenim zemljama je Hašimoto tireoiditis, koji karakteriše povišen nivo serum autoantitela i limfocitna infiltracija štitaste žlezde. Grejvsova bolest je vodeći uzrok hipertireoza na globalnom nivou. Pacijenti sa oboljenjem štitaste žlezde često zahtevaju modifikaciju dijetarnog režima. Popularne intervencije uključuju suplementaciju određenim vitaminima, mineralima i mikroelementima kao što su jod i selen. Preporučuje se ograničen unos namirnica koje sadrže goitrogene supstance jer ometaju normalnu sintezu tiroidnih hormona, povećavajući rizik za nastanak strume i hipotireoze. Primarni izvori goitrogena u ishrani su kruciferno povrće, proizvodi od soje, skrobne biljke i pojedine vrste voća. Osim esencijalnih nutrijenata, postoji sve veće interesovanje za primenu specifičnih nutraceutika u prevenciji i koterapiji bolesti štitaste žlezde, kao što su mioinozitol, L-karnitin, melatonin i rezveratrol. Trenutni dokazi ukazuju na moguće promotivne efekte ovih jedinjenja u oboljenjima štitaste žlezde. Potrebna su dalja ispitivanja koja bi pratila uticaj doze i dužine suplementacije nutraceutika i potvrdila tačne mehanizme njihovog delovanja u poremećajima funkcije štitaste žlezde.
PB  - Pharmaceutical Association of Serbia
T2  - Arhiv za farmaciju
T1  - Dietary factors and thyroid dysfunction
T1  - Dijetarni faktori i tiroidna disfunkcija
VL  - 72
IS  - 5
SP  - 455
EP  - 467
DO  - 10.5937/arhfarm72-39624
ER  - 
@article{
author = "Đuričić, Ivana and Todorović, Vanja and Dabetić, Nevena and Zrnić-Ćirić, Milica and Ivanović, Nevena and Vidović, Bojana",
year = "2022",
abstract = "Besides iodine deficiency, autoimmune Hashimoto thyroiditis is the leading cause of
hypothyroidism globally, characterized by the increased titer of thyroid autoantibodies and
destruction of thyroid cells. Graves' disease is the most common etiology of hyperthyroidism
worldwide. Patients with thyroid dysfunction often require dietary modifications. Popular
interventions include supplementation with certain vitamins and minerals, as well as trace
elements such as iodine and selenium. The intake of food containing goitrogens should be limited.
Goitrogens are substances of plant origin that interfere with the production of thyroid hormones,
increasing the risk for goiter and hypothyroidism. The primary dietary sources of goitrogens are
cruciferous vegetables, soy products, starchy plants, and some fruits. Beyond essential nutrients,
there has been an increasing interest in using specific nutraceuticals, including myoinositol, L-
carnitine, melatonin, and resveratrol, as potential preventive and therapeutic agents in thyroid
diseases. Even though current evidence promotes some beneficial outcomes of these
nutraceuticals, further investigations are needed to clarify dose-dependent effects, duration of
supplementation, combination in different clinical settings, and the exact mechanism of their
action in thyroid disorders., Pored nedostatka joda, najčešća etiologija hipotireoze u razvijenim zemljama je Hašimoto tireoiditis, koji karakteriše povišen nivo serum autoantitela i limfocitna infiltracija štitaste žlezde. Grejvsova bolest je vodeći uzrok hipertireoza na globalnom nivou. Pacijenti sa oboljenjem štitaste žlezde često zahtevaju modifikaciju dijetarnog režima. Popularne intervencije uključuju suplementaciju određenim vitaminima, mineralima i mikroelementima kao što su jod i selen. Preporučuje se ograničen unos namirnica koje sadrže goitrogene supstance jer ometaju normalnu sintezu tiroidnih hormona, povećavajući rizik za nastanak strume i hipotireoze. Primarni izvori goitrogena u ishrani su kruciferno povrće, proizvodi od soje, skrobne biljke i pojedine vrste voća. Osim esencijalnih nutrijenata, postoji sve veće interesovanje za primenu specifičnih nutraceutika u prevenciji i koterapiji bolesti štitaste žlezde, kao što su mioinozitol, L-karnitin, melatonin i rezveratrol. Trenutni dokazi ukazuju na moguće promotivne efekte ovih jedinjenja u oboljenjima štitaste žlezde. Potrebna su dalja ispitivanja koja bi pratila uticaj doze i dužine suplementacije nutraceutika i potvrdila tačne mehanizme njihovog delovanja u poremećajima funkcije štitaste žlezde.",
publisher = "Pharmaceutical Association of Serbia",
journal = "Arhiv za farmaciju",
title = "Dietary factors and thyroid dysfunction, Dijetarni faktori i tiroidna disfunkcija",
volume = "72",
number = "5",
pages = "455-467",
doi = "10.5937/arhfarm72-39624"
}
Đuričić, I., Todorović, V., Dabetić, N., Zrnić-Ćirić, M., Ivanović, N.,& Vidović, B.. (2022). Dietary factors and thyroid dysfunction. in Arhiv za farmaciju
Pharmaceutical Association of Serbia., 72(5), 455-467.
https://doi.org/10.5937/arhfarm72-39624
Đuričić I, Todorović V, Dabetić N, Zrnić-Ćirić M, Ivanović N, Vidović B. Dietary factors and thyroid dysfunction. in Arhiv za farmaciju. 2022;72(5):455-467.
doi:10.5937/arhfarm72-39624 .
Đuričić, Ivana, Todorović, Vanja, Dabetić, Nevena, Zrnić-Ćirić, Milica, Ivanović, Nevena, Vidović, Bojana, "Dietary factors and thyroid dysfunction" in Arhiv za farmaciju, 72, no. 5 (2022):455-467,
https://doi.org/10.5937/arhfarm72-39624 . .

Malnutrition induced by cancer and oncology treatment

Kostadinović, Jelena; Kotur-Stevuljević, Jelena; Ivanović, Nevena; Andrić, Zoran

(Društvo za ishranu Srbije, Beograd, 2022)

TY  - JOUR
AU  - Kostadinović, Jelena
AU  - Kotur-Stevuljević, Jelena
AU  - Ivanović, Nevena
AU  - Andrić, Zoran
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5374
AB  - Malnutrition as a consequence of the disease occurs most
often in cancer patients, not only because of the cancer
itself, but also because of the oncological treatment. The
most important cause is chemotherapy, followed by ra-
diotherapy and onco-surgery. Therefore, efforts are being
made all over the world to find different ways to solve this
difficult medical problem. Given that the mechanism of
malnutrition caused by cancer is not sufficiently elucidat-
ed, the efforts made to design an adequate approach and
treatment of this disorder are often unsuccessful. In order
to improve the nutritional status of oncology patients, their
nutritional disorder should be adequately diagnosed and
then specific measurements should be performed (deter-
mination of body composition, the proportion of water, fat,
muscle, as well as the determination of various biomarkers
in the blood, for example markers inflammation). In this way, it is possible to formulate a multimodal approach to the
treatment of malnutrition in oncology patients, which would include the intake of adequate foods, increased physical
activity and personalized supplementation.
AB  - Pothranjenost kao posledica bolesti se najčešće javlja kod
onkoloških pacijenata i to ne samo zbog samog kancera,
već i zbog onkološkog lečenja. Najznačajniji uzročnik je
hemioterapija, potom radioterapija i onko-hirurgija. Zbog
toga se širom sveta ulažu napori i pronalaze različiti načini
za rešavanje ovog teškog medicinskog problema. S obzirom
na to da mehanizam nastanka pothranjenosti uzrokovane
karcinomom nije dovoljno rasvetljen, napori koji se ulažu
da se osmisli adekvatan pristup i tretman ovog poremećaja se često neuspešno završe. Da bi se nutritivni status onko-
loških pacijenata popravio njima pre svega treba da bude dijagnostikovan nutritivni poremećaj, a zatim da se sprovedu
specifična merenja (određivanje sastava tela, udeo vode, masti, mišića, kao i da se u krvi odrede različiti biomarkeri, na
primer markeri zapaljenja). Na taj način je moguće formulisati multimodalni pristup u lečenju pothranjenosti onkoloških
bolesnika koji bi obuhvatio unos adekvatnih namirnica, povećanje fizičke aktivnosti i personalizovanu suplementaciju.
PB  - Društvo za ishranu Srbije, Beograd
T2  - Hrana i ishrana
T1  - Malnutrition induced by cancer and oncology treatment
T1  - Malnutricija uzrokovana karcinomom i onkološkom terapijom
VL  - 63
IS  - 1
SP  - 9
EP  - 16
DO  - 10.5937/hraIsh2201009K
ER  - 
@article{
author = "Kostadinović, Jelena and Kotur-Stevuljević, Jelena and Ivanović, Nevena and Andrić, Zoran",
year = "2022",
abstract = "Malnutrition as a consequence of the disease occurs most
often in cancer patients, not only because of the cancer
itself, but also because of the oncological treatment. The
most important cause is chemotherapy, followed by ra-
diotherapy and onco-surgery. Therefore, efforts are being
made all over the world to find different ways to solve this
difficult medical problem. Given that the mechanism of
malnutrition caused by cancer is not sufficiently elucidat-
ed, the efforts made to design an adequate approach and
treatment of this disorder are often unsuccessful. In order
to improve the nutritional status of oncology patients, their
nutritional disorder should be adequately diagnosed and
then specific measurements should be performed (deter-
mination of body composition, the proportion of water, fat,
muscle, as well as the determination of various biomarkers
in the blood, for example markers inflammation). In this way, it is possible to formulate a multimodal approach to the
treatment of malnutrition in oncology patients, which would include the intake of adequate foods, increased physical
activity and personalized supplementation., Pothranjenost kao posledica bolesti se najčešće javlja kod
onkoloških pacijenata i to ne samo zbog samog kancera,
već i zbog onkološkog lečenja. Najznačajniji uzročnik je
hemioterapija, potom radioterapija i onko-hirurgija. Zbog
toga se širom sveta ulažu napori i pronalaze različiti načini
za rešavanje ovog teškog medicinskog problema. S obzirom
na to da mehanizam nastanka pothranjenosti uzrokovane
karcinomom nije dovoljno rasvetljen, napori koji se ulažu
da se osmisli adekvatan pristup i tretman ovog poremećaja se često neuspešno završe. Da bi se nutritivni status onko-
loških pacijenata popravio njima pre svega treba da bude dijagnostikovan nutritivni poremećaj, a zatim da se sprovedu
specifična merenja (određivanje sastava tela, udeo vode, masti, mišića, kao i da se u krvi odrede različiti biomarkeri, na
primer markeri zapaljenja). Na taj način je moguće formulisati multimodalni pristup u lečenju pothranjenosti onkoloških
bolesnika koji bi obuhvatio unos adekvatnih namirnica, povećanje fizičke aktivnosti i personalizovanu suplementaciju.",
publisher = "Društvo za ishranu Srbije, Beograd",
journal = "Hrana i ishrana",
title = "Malnutrition induced by cancer and oncology treatment, Malnutricija uzrokovana karcinomom i onkološkom terapijom",
volume = "63",
number = "1",
pages = "9-16",
doi = "10.5937/hraIsh2201009K"
}
Kostadinović, J., Kotur-Stevuljević, J., Ivanović, N.,& Andrić, Z.. (2022). Malnutrition induced by cancer and oncology treatment. in Hrana i ishrana
Društvo za ishranu Srbije, Beograd., 63(1), 9-16.
https://doi.org/10.5937/hraIsh2201009K
Kostadinović J, Kotur-Stevuljević J, Ivanović N, Andrić Z. Malnutrition induced by cancer and oncology treatment. in Hrana i ishrana. 2022;63(1):9-16.
doi:10.5937/hraIsh2201009K .
Kostadinović, Jelena, Kotur-Stevuljević, Jelena, Ivanović, Nevena, Andrić, Zoran, "Malnutrition induced by cancer and oncology treatment" in Hrana i ishrana, 63, no. 1 (2022):9-16,
https://doi.org/10.5937/hraIsh2201009K . .

Similarities and differences in the nutritional composition of nuts and seeds in Serbia

Dodevska, Margarita; Kukić-Marković, Jelena; Sofrenić, Ivana; Tešević, Vele; Janković, Milica; Đorđević, Brižita; Ivanović, Nevena

(Frontiers Media S.A., 2022)

TY  - JOUR
AU  - Dodevska, Margarita
AU  - Kukić-Marković, Jelena
AU  - Sofrenić, Ivana
AU  - Tešević, Vele
AU  - Janković, Milica
AU  - Đorđević, Brižita
AU  - Ivanović, Nevena
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4288
AB  - Nuts and seeds are an indispensable part of the plant-based diet, which is becoming increasingly popular due to the evidence of their health benefits and contribution to sustainability and planetary health. Since the health effects of consuming nuts and seeds directly depend on their nutritional composition and consumed amount, it is essential to know the exact chemical composition of each nut and seed so that appropriate dietary interventions can be adequately planned. The present study aimed to examine the chemical composition of nuts and seeds obtained from the Serbian market and to highlight the similarities and differences in their nutritional composition. In twenty-four samples of nuts and seeds, the content of total lipids, including fatty acid profile, total proteins, including amino acid profile, total carbohydrates (sugars and fibers), phytosterols, and minerals were determined. Content of selected nutrients in grams (g) or milligrams (mg) of nuts and seeds was expressed in one portion (28 g) and as a percentage of contribution of Reference Intakes (% RI) and Dietary Reference Value (% DRV) for macronutrients and minerals, respectively. Some of the seed representatives appeared to be rich sources of essential omega-3 fatty acid, α-linolenic acid (ALA) (flax seed vs. walnut, 6.50 vs. 0.56 g per portion, respectively), dietary fibers (chia seed vs. raw almond, 10.6 vs. 3.4 g per portion, respectively), calcium (black sesame seed vs. almond roasted, 32.4% NRV vs. 8.1% NRV per portion, respectively), magnesium (hemp seed vs. Brazil nut, 38.3% NRV vs. 27.8% NRV per portion, respectively), and zinc (hemp seed vs. pine nut, 21.4% NRV vs. 17.6% NRV per portion, respectively). Our results highlighted the crucial role of seeds in the diet, especially as a better source of nutrients compared to nuts. Furthermore, it was seen that nuts and seeds are different and complementary in their composition. Thus, in order to meet the needs for certain nutrients for which nuts and seeds are used as dietary sources (essential fatty acids, minerals, dietary fibers), it would be beneficial to combine both nuts and seeds as a part of a healthy dietary pattern.
PB  - Frontiers Media S.A.
T2  - Frontiers in Nutrition
T1  - Similarities and differences in the nutritional composition of nuts and seeds in Serbia
VL  - 9
DO  - 10.3389/fnut.2022.1003125
ER  - 
@article{
author = "Dodevska, Margarita and Kukić-Marković, Jelena and Sofrenić, Ivana and Tešević, Vele and Janković, Milica and Đorđević, Brižita and Ivanović, Nevena",
year = "2022",
abstract = "Nuts and seeds are an indispensable part of the plant-based diet, which is becoming increasingly popular due to the evidence of their health benefits and contribution to sustainability and planetary health. Since the health effects of consuming nuts and seeds directly depend on their nutritional composition and consumed amount, it is essential to know the exact chemical composition of each nut and seed so that appropriate dietary interventions can be adequately planned. The present study aimed to examine the chemical composition of nuts and seeds obtained from the Serbian market and to highlight the similarities and differences in their nutritional composition. In twenty-four samples of nuts and seeds, the content of total lipids, including fatty acid profile, total proteins, including amino acid profile, total carbohydrates (sugars and fibers), phytosterols, and minerals were determined. Content of selected nutrients in grams (g) or milligrams (mg) of nuts and seeds was expressed in one portion (28 g) and as a percentage of contribution of Reference Intakes (% RI) and Dietary Reference Value (% DRV) for macronutrients and minerals, respectively. Some of the seed representatives appeared to be rich sources of essential omega-3 fatty acid, α-linolenic acid (ALA) (flax seed vs. walnut, 6.50 vs. 0.56 g per portion, respectively), dietary fibers (chia seed vs. raw almond, 10.6 vs. 3.4 g per portion, respectively), calcium (black sesame seed vs. almond roasted, 32.4% NRV vs. 8.1% NRV per portion, respectively), magnesium (hemp seed vs. Brazil nut, 38.3% NRV vs. 27.8% NRV per portion, respectively), and zinc (hemp seed vs. pine nut, 21.4% NRV vs. 17.6% NRV per portion, respectively). Our results highlighted the crucial role of seeds in the diet, especially as a better source of nutrients compared to nuts. Furthermore, it was seen that nuts and seeds are different and complementary in their composition. Thus, in order to meet the needs for certain nutrients for which nuts and seeds are used as dietary sources (essential fatty acids, minerals, dietary fibers), it would be beneficial to combine both nuts and seeds as a part of a healthy dietary pattern.",
publisher = "Frontiers Media S.A.",
journal = "Frontiers in Nutrition",
title = "Similarities and differences in the nutritional composition of nuts and seeds in Serbia",
volume = "9",
doi = "10.3389/fnut.2022.1003125"
}
Dodevska, M., Kukić-Marković, J., Sofrenić, I., Tešević, V., Janković, M., Đorđević, B.,& Ivanović, N.. (2022). Similarities and differences in the nutritional composition of nuts and seeds in Serbia. in Frontiers in Nutrition
Frontiers Media S.A.., 9.
https://doi.org/10.3389/fnut.2022.1003125
Dodevska M, Kukić-Marković J, Sofrenić I, Tešević V, Janković M, Đorđević B, Ivanović N. Similarities and differences in the nutritional composition of nuts and seeds in Serbia. in Frontiers in Nutrition. 2022;9.
doi:10.3389/fnut.2022.1003125 .
Dodevska, Margarita, Kukić-Marković, Jelena, Sofrenić, Ivana, Tešević, Vele, Janković, Milica, Đorđević, Brižita, Ivanović, Nevena, "Similarities and differences in the nutritional composition of nuts and seeds in Serbia" in Frontiers in Nutrition, 9 (2022),
https://doi.org/10.3389/fnut.2022.1003125 . .
1
10
8

Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels

Ivanović, Nevena; Radosavljević, Branimir; Zeković, Milica; Korčok, Davor; Ignjatović, Svetlana; Đorđević, Brižita; Milinković, Neda

(Springer Nature B.V., 2022)

TY  - JOUR
AU  - Ivanović, Nevena
AU  - Radosavljević, Branimir
AU  - Zeković, Milica
AU  - Korčok, Davor
AU  - Ignjatović, Svetlana
AU  - Đorđević, Brižita
AU  - Milinković, Neda
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4048
AB  - This study aimed to investigate the short-term effects of three magnesium (Mg) dietary supplements containing mineral immediately available for absorption on Mg biochemical status indices (ionized and total Mg), as well as their effects on electrolytes levels in healthy female young adults (n = 61). After a 10-days intervention period supplementation with powder/granulate containing Mg oxide led to an increase in both ionized Mg concentration and % in total Mg in comparison with the baseline. Supplementation with Mg citrate was associated with the significant increase in % of ionized fraction and decrease in serum total Mg concentration. By contrast, among participants consuming Mg carbonate in the form of effervescent tablets ionized Mg concentration and % in total Mg decreased, without detectable changes in serum total Mg. In conclusion, after the short-term supplementation period, Mg oxide demonstrated superior bioavailability compared to the other examined Mg supplements without affecting other minerals’ levels.
PB  - Springer Nature B.V.
T2  - BioMetals
T1  - Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels
VL  - 35
SP  - 267
EP  - 283
DO  - 10.1007/s10534-022-00363-y
ER  - 
@article{
author = "Ivanović, Nevena and Radosavljević, Branimir and Zeković, Milica and Korčok, Davor and Ignjatović, Svetlana and Đorđević, Brižita and Milinković, Neda",
year = "2022",
abstract = "This study aimed to investigate the short-term effects of three magnesium (Mg) dietary supplements containing mineral immediately available for absorption on Mg biochemical status indices (ionized and total Mg), as well as their effects on electrolytes levels in healthy female young adults (n = 61). After a 10-days intervention period supplementation with powder/granulate containing Mg oxide led to an increase in both ionized Mg concentration and % in total Mg in comparison with the baseline. Supplementation with Mg citrate was associated with the significant increase in % of ionized fraction and decrease in serum total Mg concentration. By contrast, among participants consuming Mg carbonate in the form of effervescent tablets ionized Mg concentration and % in total Mg decreased, without detectable changes in serum total Mg. In conclusion, after the short-term supplementation period, Mg oxide demonstrated superior bioavailability compared to the other examined Mg supplements without affecting other minerals’ levels.",
publisher = "Springer Nature B.V.",
journal = "BioMetals",
title = "Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels",
volume = "35",
pages = "267-283",
doi = "10.1007/s10534-022-00363-y"
}
Ivanović, N., Radosavljević, B., Zeković, M., Korčok, D., Ignjatović, S., Đorđević, B.,& Milinković, N.. (2022). Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels. in BioMetals
Springer Nature B.V.., 35, 267-283.
https://doi.org/10.1007/s10534-022-00363-y
Ivanović N, Radosavljević B, Zeković M, Korčok D, Ignjatović S, Đorđević B, Milinković N. Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels. in BioMetals. 2022;35:267-283.
doi:10.1007/s10534-022-00363-y .
Ivanović, Nevena, Radosavljević, Branimir, Zeković, Milica, Korčok, Davor, Ignjatović, Svetlana, Đorđević, Brižita, Milinković, Neda, "Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels" in BioMetals, 35 (2022):267-283,
https://doi.org/10.1007/s10534-022-00363-y . .
3
3
3

Quality characteristics of oils from selected edible seeds

Dodevska, Margarita; Ivanović, Nevena; Kukić-Marković, Jelena; Đorđević, Brižita

(Croatian Society of Food Technologists, Biotechnologists and Nutritionists, Zagreb, Croatia, 2022)

TY  - CONF
AU  - Dodevska, Margarita
AU  - Ivanović, Nevena
AU  - Kukić-Marković, Jelena
AU  - Đorđević, Brižita
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4623
AB  - Many types of vegetable oils produce around the world. They are useful in nutrition,
prevention and treatment of diseases. Some oils traditionally have been well known for a long
time and have been shown many potential health benefits, such as, cardioprotective effect,
effect on digestion, risk of some cancer and it is also used in the treatment of skin infections.
This work was conducted to study some quality criteria of oil extracted from seven different
raw seeds purchased in the Serbian market, namely: sunflowers, sesame seeds, black sesame
seeds, tickles seeds, chia seeds, flax seeds and hemp seeds. Oils are essentially regarded in
terms of quality based on their free fatty acid, iodine value and peroxides value. Oils were
extracted from the seeds by cold extraction with petroleum ether. Quality characteristics,
such as refractive index, acid value, peroxide value, iodine value and saponification value and
unsaponifiable matter were determined. For the determination of these parameters, official
methods (ISO 6320; ISO660; ISO 3960; ISO 3961; ISO 3657 and ISO 18609, respectively) were
used. The contents of investigated parameters in seed samples were determined in the range
of 1.467 to 1.485 nD for refractive index; 1.62 to 4.95 mg KOH/g for acid value; 5.21 to 7.45
for peroxide value; 118 to 197 for iodine value; 180 to 193 for saponification value and 3.14
to 7.26 g/kg for the unsaponifiable matter.
Data obtained in this investigation indicate that all quality parameters of the seed samples,
except peroxide value , comply with the national and Codex standards.
PB  - Croatian Society of Food Technologists, Biotechnologists and Nutritionists, Zagreb, Croatia
C3  - 10 th International Congress of Food Technologists, Biotechnologists and Nutritionists, Book of Abstracts
T1  - Quality characteristics of oils from selected edible seeds
SP  - 172
EP  - 172
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4623
ER  - 
@conference{
author = "Dodevska, Margarita and Ivanović, Nevena and Kukić-Marković, Jelena and Đorđević, Brižita",
year = "2022",
abstract = "Many types of vegetable oils produce around the world. They are useful in nutrition,
prevention and treatment of diseases. Some oils traditionally have been well known for a long
time and have been shown many potential health benefits, such as, cardioprotective effect,
effect on digestion, risk of some cancer and it is also used in the treatment of skin infections.
This work was conducted to study some quality criteria of oil extracted from seven different
raw seeds purchased in the Serbian market, namely: sunflowers, sesame seeds, black sesame
seeds, tickles seeds, chia seeds, flax seeds and hemp seeds. Oils are essentially regarded in
terms of quality based on their free fatty acid, iodine value and peroxides value. Oils were
extracted from the seeds by cold extraction with petroleum ether. Quality characteristics,
such as refractive index, acid value, peroxide value, iodine value and saponification value and
unsaponifiable matter were determined. For the determination of these parameters, official
methods (ISO 6320; ISO660; ISO 3960; ISO 3961; ISO 3657 and ISO 18609, respectively) were
used. The contents of investigated parameters in seed samples were determined in the range
of 1.467 to 1.485 nD for refractive index; 1.62 to 4.95 mg KOH/g for acid value; 5.21 to 7.45
for peroxide value; 118 to 197 for iodine value; 180 to 193 for saponification value and 3.14
to 7.26 g/kg for the unsaponifiable matter.
Data obtained in this investigation indicate that all quality parameters of the seed samples,
except peroxide value , comply with the national and Codex standards.",
publisher = "Croatian Society of Food Technologists, Biotechnologists and Nutritionists, Zagreb, Croatia",
journal = "10 th International Congress of Food Technologists, Biotechnologists and Nutritionists, Book of Abstracts",
title = "Quality characteristics of oils from selected edible seeds",
pages = "172-172",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4623"
}
Dodevska, M., Ivanović, N., Kukić-Marković, J.,& Đorđević, B.. (2022). Quality characteristics of oils from selected edible seeds. in 10 th International Congress of Food Technologists, Biotechnologists and Nutritionists, Book of Abstracts
Croatian Society of Food Technologists, Biotechnologists and Nutritionists, Zagreb, Croatia., 172-172.
https://hdl.handle.net/21.15107/rcub_farfar_4623
Dodevska M, Ivanović N, Kukić-Marković J, Đorđević B. Quality characteristics of oils from selected edible seeds. in 10 th International Congress of Food Technologists, Biotechnologists and Nutritionists, Book of Abstracts. 2022;:172-172.
https://hdl.handle.net/21.15107/rcub_farfar_4623 .
Dodevska, Margarita, Ivanović, Nevena, Kukić-Marković, Jelena, Đorđević, Brižita, "Quality characteristics of oils from selected edible seeds" in 10 th International Congress of Food Technologists, Biotechnologists and Nutritionists, Book of Abstracts (2022):172-172,
https://hdl.handle.net/21.15107/rcub_farfar_4623 .

Pharmacy students’ perspective on online lectures during the COVID-19 pandemic: A case study from the University of Belgrade

Malenović, Anđelija; Kovačević, Milena; Ivanović, Nevena; Protić, Ana; Parojčić, Jelena

(European Association of Faculties of Pharmacy, 2022)

TY  - CONF
AU  - Malenović, Anđelija
AU  - Kovačević, Milena
AU  - Ivanović, Nevena
AU  - Protić, Ana
AU  - Parojčić, Jelena
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4381
AB  - Introduction: Synchronous lectures tend to be used as the
prevalent method of online instruction, irrespective of
notable differences and obvious limitations when compared
to their in-person delivery. Study aim was to assess students’
perspective on online lectures held during the emergency
remote teaching (ERT) shift due to the COVID-19 pandemic.
Method: Students were invited to take part in online survey
related to their experience with ERT. Survey included 25 items
related to: satisfaction (14 items), motivation (three items),
interaction with peers and lecturers (four items), and
perceived challenges (four items). A 5-point Likert scale was
employed. Statistical analysis was performed using the SPSS
software.
Results: A total of 387 students participated in the survey.
The majority of respondents (79.3%) were junior students.
Among the respondents, 72.6% reported no previous
experience with online learning. Although a relatively high
level of satisfaction was reported (mean score 3.91 ± 0.75),
challenges were also scored relatively high (3.05 ± 0.99),
while interaction was scored somewhat lower (2.98 ± 0.73),
and the lowest mean score was observed for motivation (2.73
± 0.58). Students reported having trouble maintaining
motivation, concentration and focus during online lectures,
which usually took many hours per day. Interaction with
peers was reported as unsatisfactory (2.48 ± 1.46), whereas it
was more feasible with lecturers (3.24 ± 1.42). Students were
quite satisfied with the ability to organise their time flexibly
(71.4%), and with the workload (54.5%), while they were less
convinced that online sessions provided enough
opportunities to reflect on what was learnt (50.1% agree,
25.1% neither agree nor disagree).
Conclusions: The results obtained indicate that students are
somewhat hesitant with respect to online lectures as the
main mode of instruction. Lectures, generally, place students
in a passive role, which is further increased in online delivery.
In order to support students’ engagement and success, online
lectures should be combined with more active instructional
strategies.
PB  - European Association of Faculties of Pharmacy
PB  - International Pharmaceutical Federation (FIP)
C3  - Pharmacy Education
T1  - Pharmacy students’ perspective on online lectures during the COVID-19 pandemic: A case study from the University of Belgrade
VL  - 22
IS  - 3
SP  - 8
EP  - 8
DO  - 10.46542/pe.2022.223.135
ER  - 
@conference{
author = "Malenović, Anđelija and Kovačević, Milena and Ivanović, Nevena and Protić, Ana and Parojčić, Jelena",
year = "2022",
abstract = "Introduction: Synchronous lectures tend to be used as the
prevalent method of online instruction, irrespective of
notable differences and obvious limitations when compared
to their in-person delivery. Study aim was to assess students’
perspective on online lectures held during the emergency
remote teaching (ERT) shift due to the COVID-19 pandemic.
Method: Students were invited to take part in online survey
related to their experience with ERT. Survey included 25 items
related to: satisfaction (14 items), motivation (three items),
interaction with peers and lecturers (four items), and
perceived challenges (four items). A 5-point Likert scale was
employed. Statistical analysis was performed using the SPSS
software.
Results: A total of 387 students participated in the survey.
The majority of respondents (79.3%) were junior students.
Among the respondents, 72.6% reported no previous
experience with online learning. Although a relatively high
level of satisfaction was reported (mean score 3.91 ± 0.75),
challenges were also scored relatively high (3.05 ± 0.99),
while interaction was scored somewhat lower (2.98 ± 0.73),
and the lowest mean score was observed for motivation (2.73
± 0.58). Students reported having trouble maintaining
motivation, concentration and focus during online lectures,
which usually took many hours per day. Interaction with
peers was reported as unsatisfactory (2.48 ± 1.46), whereas it
was more feasible with lecturers (3.24 ± 1.42). Students were
quite satisfied with the ability to organise their time flexibly
(71.4%), and with the workload (54.5%), while they were less
convinced that online sessions provided enough
opportunities to reflect on what was learnt (50.1% agree,
25.1% neither agree nor disagree).
Conclusions: The results obtained indicate that students are
somewhat hesitant with respect to online lectures as the
main mode of instruction. Lectures, generally, place students
in a passive role, which is further increased in online delivery.
In order to support students’ engagement and success, online
lectures should be combined with more active instructional
strategies.",
publisher = "European Association of Faculties of Pharmacy, International Pharmaceutical Federation (FIP)",
journal = "Pharmacy Education",
title = "Pharmacy students’ perspective on online lectures during the COVID-19 pandemic: A case study from the University of Belgrade",
volume = "22",
number = "3",
pages = "8-8",
doi = "10.46542/pe.2022.223.135"
}
Malenović, A., Kovačević, M., Ivanović, N., Protić, A.,& Parojčić, J.. (2022). Pharmacy students’ perspective on online lectures during the COVID-19 pandemic: A case study from the University of Belgrade. in Pharmacy Education
European Association of Faculties of Pharmacy., 22(3), 8-8.
https://doi.org/10.46542/pe.2022.223.135
Malenović A, Kovačević M, Ivanović N, Protić A, Parojčić J. Pharmacy students’ perspective on online lectures during the COVID-19 pandemic: A case study from the University of Belgrade. in Pharmacy Education. 2022;22(3):8-8.
doi:10.46542/pe.2022.223.135 .
Malenović, Anđelija, Kovačević, Milena, Ivanović, Nevena, Protić, Ana, Parojčić, Jelena, "Pharmacy students’ perspective on online lectures during the COVID-19 pandemic: A case study from the University of Belgrade" in Pharmacy Education, 22, no. 3 (2022):8-8,
https://doi.org/10.46542/pe.2022.223.135 . .
1

Pharmacy students' perspectives on online lectures during the COVID – 19 pandemic – case study from the University of Belgrade.

Malenović, Anđelija; Kovačević, Milena; Ivanović, Nevena; Protić, Ana; Parojčić, Jelena

(European Association of Faculties of Pharmacy, 2022)

TY  - CONF
AU  - Malenović, Anđelija
AU  - Kovačević, Milena
AU  - Ivanović, Nevena
AU  - Protić, Ana
AU  - Parojčić, Jelena
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4375
AB  - Synchronous lectures tend to be used as the prevalent
method of online instruction, irrespective of notable differences
and obvious limitations when compared to their in-person delivery.
Study aim was to assess students’ perspective on online lectures
held during the emergency remote teaching (ERT) due to COVID-19
pandemic.
Method: Students were invited to take part in online survey related
to their experience with ERT. Survey included 25 items related to:
satisfaction (14 items), motivation (3 items), interaction with peers
and lecturers (4 items), and perceived challenges (4 items). A 5-point
Likert scale was employed. Statistical analysis was performed using
the SPSS software.
Results: A total of 387 students participated in the survey. Majority
of respondents (79.3%) were junior students. Among them, 72.6%
reported no previous experience with online learning. Although
relatively high level of satisfaction was reported (mean score
3.91±0.75), challenges were also scored relatively high (3.05±0.99),
while interaction was scored somewhat lower (2.98±0.73), and the
least mean score was observed for motivation (2.73±0.58). Students
reported having trouble to keep motivation, concentration and
focus during online lectures, which usually took long hours per day.
Interaction with peers was reported as unsatisfactory (2.48±1.46),
whereas it was more feasible with lecturers (3.24±1.42). Students
were quite satisfied with the possibility to organize their time flexibly
(71.4%), and with respect to the workload (54.5%), while they were
less convinced that online sessions provide enough opportunities
to reflect on what has been learnt (50,1% agree, 25,1% neither
agree nor disagree).
Conclusions: The results obtained indicate that students are
somewhat hesitant with respect to online lectures as the main mode
of instruction. Lectures, generally, place students in a passive role,
which is further increased in online delivery. In order to support
students’ engagement and success, online lectures should be
combined with more active instructional strategies.
PB  - European Association of Faculties of Pharmacy
C3  - EAFP Conference 2022, Towards Pharmacy 5.0 Education - Abstract Book
T1  - Pharmacy students' perspectives on online lectures during the COVID – 19 pandemic – case study from the University of Belgrade.
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4375
ER  - 
@conference{
author = "Malenović, Anđelija and Kovačević, Milena and Ivanović, Nevena and Protić, Ana and Parojčić, Jelena",
year = "2022",
abstract = "Synchronous lectures tend to be used as the prevalent
method of online instruction, irrespective of notable differences
and obvious limitations when compared to their in-person delivery.
Study aim was to assess students’ perspective on online lectures
held during the emergency remote teaching (ERT) due to COVID-19
pandemic.
Method: Students were invited to take part in online survey related
to their experience with ERT. Survey included 25 items related to:
satisfaction (14 items), motivation (3 items), interaction with peers
and lecturers (4 items), and perceived challenges (4 items). A 5-point
Likert scale was employed. Statistical analysis was performed using
the SPSS software.
Results: A total of 387 students participated in the survey. Majority
of respondents (79.3%) were junior students. Among them, 72.6%
reported no previous experience with online learning. Although
relatively high level of satisfaction was reported (mean score
3.91±0.75), challenges were also scored relatively high (3.05±0.99),
while interaction was scored somewhat lower (2.98±0.73), and the
least mean score was observed for motivation (2.73±0.58). Students
reported having trouble to keep motivation, concentration and
focus during online lectures, which usually took long hours per day.
Interaction with peers was reported as unsatisfactory (2.48±1.46),
whereas it was more feasible with lecturers (3.24±1.42). Students
were quite satisfied with the possibility to organize their time flexibly
(71.4%), and with respect to the workload (54.5%), while they were
less convinced that online sessions provide enough opportunities
to reflect on what has been learnt (50,1% agree, 25,1% neither
agree nor disagree).
Conclusions: The results obtained indicate that students are
somewhat hesitant with respect to online lectures as the main mode
of instruction. Lectures, generally, place students in a passive role,
which is further increased in online delivery. In order to support
students’ engagement and success, online lectures should be
combined with more active instructional strategies.",
publisher = "European Association of Faculties of Pharmacy",
journal = "EAFP Conference 2022, Towards Pharmacy 5.0 Education - Abstract Book",
title = "Pharmacy students' perspectives on online lectures during the COVID – 19 pandemic – case study from the University of Belgrade.",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4375"
}
Malenović, A., Kovačević, M., Ivanović, N., Protić, A.,& Parojčić, J.. (2022). Pharmacy students' perspectives on online lectures during the COVID – 19 pandemic – case study from the University of Belgrade.. in EAFP Conference 2022, Towards Pharmacy 5.0 Education - Abstract Book
European Association of Faculties of Pharmacy..
https://hdl.handle.net/21.15107/rcub_farfar_4375
Malenović A, Kovačević M, Ivanović N, Protić A, Parojčić J. Pharmacy students' perspectives on online lectures during the COVID – 19 pandemic – case study from the University of Belgrade.. in EAFP Conference 2022, Towards Pharmacy 5.0 Education - Abstract Book. 2022;.
https://hdl.handle.net/21.15107/rcub_farfar_4375 .
Malenović, Anđelija, Kovačević, Milena, Ivanović, Nevena, Protić, Ana, Parojčić, Jelena, "Pharmacy students' perspectives on online lectures during the COVID – 19 pandemic – case study from the University of Belgrade." in EAFP Conference 2022, Towards Pharmacy 5.0 Education - Abstract Book (2022),
https://hdl.handle.net/21.15107/rcub_farfar_4375 .

Magnesium supplementation and iron status among female students: the intervention study

Milinković, Neda; Zeković, Milica; Dodevska, Margarita; Đorđević, Brižita; Radosavljević, Branimir; Ignjatović, Svetlana; Ivanović, Nevena

(Beograd : Društvo medicinskih biohemičara Srbije, 2022)

TY  - JOUR
AU  - Milinković, Neda
AU  - Zeković, Milica
AU  - Dodevska, Margarita
AU  - Đorđević, Brižita
AU  - Radosavljević, Branimir
AU  - Ignjatović, Svetlana
AU  - Ivanović, Nevena
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4256
AB  - Background: Literature data indicate the benefit of magne-
sium (Mg) supplementation. The aim of this study was to
examine the effect of short-term Mg supplementation on
iron status in healthy female participants.
Methods: One hundred healthy female students of the
University of Belgrade - Faculty of Pharmacy participated the
study during eleven intervention days. Students ingested Mg
preparations with the same dose of the active substance. The
analysis included the measurement of serum iron, unsaturat-
ed iron binding capacity (UIBC), total iron binding capacity
(TIBC), total Mg (tMg), ionized Mg (iMg), complete blood
count, met-, carboxy- and oxy-haemoglobin (metHgb,
COHgb, O2Hgb). Transferrin concentrations and percentage
of transferrin saturation (SAT) were calculated manually. The
association among the analyzed biochemical parameters was
examined using polynomial regression. A principal compo-
nent analysis (PCA) was used for the evaluation of interde-
pendence between the analyzed parameters.
Results: A statistically significant trend for change in O2Hgb
(%) by tertiles of iMg concentrations was found (P = 0.029).
Serum tMg reached significant positive correlation with the
SAT at concentration levels greater than 0.9 mmol/L, after
11 days of intervention (R2=0.116). Ionized Mg in a con-
centration higher than 0.6 mmol/L is positively correlated
with SAT and serum Fe (R2=0.214; 0.199, respectively).
PCA revealed variability of 64.7% for two axes after 11 days.
Conclusions: Mg supplementation leads to an improvement
in the certain iron status parameters even in individuals with
optimal levels of these indices. However, caution should be
exercised when supplementing Mg, and laboratory monitor-
ing of the interaction is required.
AB  - Uvod: Literaturni podaci ukazuju na benefit suplementacije magnezijumom (Mg). Cilj ove studije bio je da se ispita uticaj kratkotrajne suplementacije Mg na status gvožđa kod zdravih žena. Metode: Sto zdravih studentkinja Univerzitet u Beogradu - Farmaceutskog fakulteta je učestvovalo u istraživanju tokom jedanaest dana intervencije. Studenti su uzimali preparate Mg sa istom dozom aktivne supstance. U serumu je određivano gvožđe, nezasićen kapacitet vezivanja gvožđa (UIBC), ukupan kapacitet vezivanja gvožđa (TIBC), ukupan Mg (tMg), jonizovni Mg (iMg), kompletna krvna slika, met-, karboksiioksihemoglobin (metHgb, COHgb, O2Hgb). Transferin i saturacija transferina (SAT) su izračunati ručno. Povezanost analiziranih biohemijskih parametara je ispitana pomoću polinomalne regresije. Za procenu međuzavisnosti između analiziranih parametara korišćena je analiza glavnih komponenti (PCA). Rezultati: Utvrđen je statistički značajan trend promene O2Hgb (%) po tertilima koncentracija iMg (P = 0,029). Ukupan Mg je dostigao značajnu pozitivnu korelaciju sa SAT pri koncentracijama većim od 0,9 mmol/L, nakon 11 dana intervencije (R2 = 0,116). Jonizovani Mg u koncentraciji većoj od 0,6 mmol/L pozitivno korelira sa SAT i gvožđem (R2 = 0,214; 0,199, redom). PCA analizom je pokazana varijabilnost od 64,7% za dve ose nakon 11 dana. Zaključak: Suplementacija Mg dovodi do poboljšanja određenih parametara statusa gvožđa čak i kod pojedinaca sa optimalnim nivoima ovih parametara. Međutim treba biti oprezan pri suplementaciji Mg, a dodatno je neophodno i laboratorijsko praćenje ovih interakcija.
PB  - Beograd : Društvo medicinskih biohemičara Srbije
T2  - Journal of Medical Biochemistry
T1  - Magnesium supplementation and iron status among female students: the intervention study
T1  - Suplementacija magnezijuma i status gvožđa kod studentkinja - studija intervencije
VL  - 41
IS  - 3
SP  - 316
EP  - 326
DO  - 10.5937/jomb0-33898
ER  - 
@article{
author = "Milinković, Neda and Zeković, Milica and Dodevska, Margarita and Đorđević, Brižita and Radosavljević, Branimir and Ignjatović, Svetlana and Ivanović, Nevena",
year = "2022",
abstract = "Background: Literature data indicate the benefit of magne-
sium (Mg) supplementation. The aim of this study was to
examine the effect of short-term Mg supplementation on
iron status in healthy female participants.
Methods: One hundred healthy female students of the
University of Belgrade - Faculty of Pharmacy participated the
study during eleven intervention days. Students ingested Mg
preparations with the same dose of the active substance. The
analysis included the measurement of serum iron, unsaturat-
ed iron binding capacity (UIBC), total iron binding capacity
(TIBC), total Mg (tMg), ionized Mg (iMg), complete blood
count, met-, carboxy- and oxy-haemoglobin (metHgb,
COHgb, O2Hgb). Transferrin concentrations and percentage
of transferrin saturation (SAT) were calculated manually. The
association among the analyzed biochemical parameters was
examined using polynomial regression. A principal compo-
nent analysis (PCA) was used for the evaluation of interde-
pendence between the analyzed parameters.
Results: A statistically significant trend for change in O2Hgb
(%) by tertiles of iMg concentrations was found (P = 0.029).
Serum tMg reached significant positive correlation with the
SAT at concentration levels greater than 0.9 mmol/L, after
11 days of intervention (R2=0.116). Ionized Mg in a con-
centration higher than 0.6 mmol/L is positively correlated
with SAT and serum Fe (R2=0.214; 0.199, respectively).
PCA revealed variability of 64.7% for two axes after 11 days.
Conclusions: Mg supplementation leads to an improvement
in the certain iron status parameters even in individuals with
optimal levels of these indices. However, caution should be
exercised when supplementing Mg, and laboratory monitor-
ing of the interaction is required., Uvod: Literaturni podaci ukazuju na benefit suplementacije magnezijumom (Mg). Cilj ove studije bio je da se ispita uticaj kratkotrajne suplementacije Mg na status gvožđa kod zdravih žena. Metode: Sto zdravih studentkinja Univerzitet u Beogradu - Farmaceutskog fakulteta je učestvovalo u istraživanju tokom jedanaest dana intervencije. Studenti su uzimali preparate Mg sa istom dozom aktivne supstance. U serumu je određivano gvožđe, nezasićen kapacitet vezivanja gvožđa (UIBC), ukupan kapacitet vezivanja gvožđa (TIBC), ukupan Mg (tMg), jonizovni Mg (iMg), kompletna krvna slika, met-, karboksiioksihemoglobin (metHgb, COHgb, O2Hgb). Transferin i saturacija transferina (SAT) su izračunati ručno. Povezanost analiziranih biohemijskih parametara je ispitana pomoću polinomalne regresije. Za procenu međuzavisnosti između analiziranih parametara korišćena je analiza glavnih komponenti (PCA). Rezultati: Utvrđen je statistički značajan trend promene O2Hgb (%) po tertilima koncentracija iMg (P = 0,029). Ukupan Mg je dostigao značajnu pozitivnu korelaciju sa SAT pri koncentracijama većim od 0,9 mmol/L, nakon 11 dana intervencije (R2 = 0,116). Jonizovani Mg u koncentraciji većoj od 0,6 mmol/L pozitivno korelira sa SAT i gvožđem (R2 = 0,214; 0,199, redom). PCA analizom je pokazana varijabilnost od 64,7% za dve ose nakon 11 dana. Zaključak: Suplementacija Mg dovodi do poboljšanja određenih parametara statusa gvožđa čak i kod pojedinaca sa optimalnim nivoima ovih parametara. Međutim treba biti oprezan pri suplementaciji Mg, a dodatno je neophodno i laboratorijsko praćenje ovih interakcija.",
publisher = "Beograd : Društvo medicinskih biohemičara Srbije",
journal = "Journal of Medical Biochemistry",
title = "Magnesium supplementation and iron status among female students: the intervention study, Suplementacija magnezijuma i status gvožđa kod studentkinja - studija intervencije",
volume = "41",
number = "3",
pages = "316-326",
doi = "10.5937/jomb0-33898"
}
Milinković, N., Zeković, M., Dodevska, M., Đorđević, B., Radosavljević, B., Ignjatović, S.,& Ivanović, N.. (2022). Magnesium supplementation and iron status among female students: the intervention study. in Journal of Medical Biochemistry
Beograd : Društvo medicinskih biohemičara Srbije., 41(3), 316-326.
https://doi.org/10.5937/jomb0-33898
Milinković N, Zeković M, Dodevska M, Đorđević B, Radosavljević B, Ignjatović S, Ivanović N. Magnesium supplementation and iron status among female students: the intervention study. in Journal of Medical Biochemistry. 2022;41(3):316-326.
doi:10.5937/jomb0-33898 .
Milinković, Neda, Zeković, Milica, Dodevska, Margarita, Đorđević, Brižita, Radosavljević, Branimir, Ignjatović, Svetlana, Ivanović, Nevena, "Magnesium supplementation and iron status among female students: the intervention study" in Journal of Medical Biochemistry, 41, no. 3 (2022):316-326,
https://doi.org/10.5937/jomb0-33898 . .
5
2
2

Influence of various dietary regimes upon immunity

Đorđević, Brižita; Ivanović, Nevena

(Savez farmaceutskih udruženja Srbije (SFUS), 2022)

TY  - CONF
AU  - Đorđević, Brižita
AU  - Ivanović, Nevena
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4439
AB  - Although it is considered that optimal nutrition could provide all essential nutrients
and active compounds, various dietary regimes are often not following the relevant
recommendations. On the contrary, nutritional status is closely related to the immune
system. Namely, insufficient caloric intake or a lack of a nutrient can primarily weaken the
immune response. The gastrointestinal tract plays an essential role in the function of the
immune system, which is both the place of absorption of nutrients and the body's immune
defence. Globally, the most prominent cause of immunodeficiencies is undernutrition and
starvation, up to 50 % of undeveloped countries' populations. Undernutrition negatively
affects both innate and adaptive immunity; considering these facts, it is clear that a
prolonged low caloric intake could affect immunity adversely. Since the sixties, World Health
Organisation has considered relations between nutrition and immunity, and nutritional
immunology is a newer scientific discipline. Later, the precise relationship between low
protein intake and lymphoid tissue involution was defined. Generally, the deficiencies of
energy, proteins, iron, iodine, vitamin A, zinc and calcium are the most common. It is
estimated that every third person is being affected globally. Prolonged hypercaloric intake
and resulting obesity could also exhibit immunocompromising effects through inflammation
and hyperactivation of the immune system. The negative impact on the immune system
could also be provoked by intense physical activity, infective agents, and emotional stress.
AB  - Iako se stručna javnost slaže da se odgovarajući unos nutrijenata može obezbediti
dobro izbalansiranom ishranom, u opštoj populaciji su zastupljeni različiti režimi ishrane
koji u potpunosti ne slede preporuke relevantnih tela. Sa druge strane, nutritivni status je u
bliskoj vezi sa imunskim sistemom. Naime, nedovoljan kalorijski unos ili nedostatak nekog
nutrijenta prvenstveno može dovesti do slabljenja imunskog odgovora. Važnu ulogu u
funkciji imunskog sistema ima i gastrointestinalni trakt koji predstavlja mesto apsopcije
nutrijenata, ali i imunološke odbrane organizma. Najčešć i uzrok imunodeficijencije u svetu je
pothranjenost. i to kod čak 50% stanovništva u zemljama trećeg sveta. Pothranjenost dovodi
do poremećaja i urođenog i stečenog imunskog odgovora. Imajući u vidu ove činjenice, jasno
se nameće zaključak da dugotrajni režimi smanjenog kalorijskog unosa mogu ispoljiti sličan
efekat. Nutritivna imunologija je relativno mlada naučna disciplina koja se bavi ovom
problematikom, a šezdesetih godina izlazi monografija Svetske zdravstvene organizacije na
ovu temu. Sedamdesetih je uspostavljena jasna veza izmedju proteinske malnutricije i
involucije limfoidnog tkiva, pa i timusa. Globalno, među najzastupljenijijim deficitima su
deficit energetskog unosa, proteina, gvožđa, joda, vitamina A, D, cinka i kalcijuma, a procena
je da je svaka treća osoba u svetu pogođena nekim od nutritivnih deficita. Dugotrajan
prekomeran kalorijski unos kao i posledična gojaznost, takođe mogu ispoljiti
imunokompromitujući efekat i to kroz inflamaciju, kao i hiperaktivaciju imunskog odgovora.
Negativan efekat na imunski sistem mogu imati i veoma intenzivan fizički napor, kao i
psihički stress, i različiti infektivni agensi.
PB  - Savez farmaceutskih udruženja Srbije (SFUS)
C3  - Arhiv za farmaciju
T1  - Influence of various dietary regimes upon immunity
T1  - Uticaj različitih dijetarnih režima na imunitet
VL  - 72
IS  - 4 suplement
SP  - S11
EP  - S12
UR  - https://hdl.handle.net/21.15107/rcub_farfar_4439
ER  - 
@conference{
author = "Đorđević, Brižita and Ivanović, Nevena",
year = "2022",
abstract = "Although it is considered that optimal nutrition could provide all essential nutrients
and active compounds, various dietary regimes are often not following the relevant
recommendations. On the contrary, nutritional status is closely related to the immune
system. Namely, insufficient caloric intake or a lack of a nutrient can primarily weaken the
immune response. The gastrointestinal tract plays an essential role in the function of the
immune system, which is both the place of absorption of nutrients and the body's immune
defence. Globally, the most prominent cause of immunodeficiencies is undernutrition and
starvation, up to 50 % of undeveloped countries' populations. Undernutrition negatively
affects both innate and adaptive immunity; considering these facts, it is clear that a
prolonged low caloric intake could affect immunity adversely. Since the sixties, World Health
Organisation has considered relations between nutrition and immunity, and nutritional
immunology is a newer scientific discipline. Later, the precise relationship between low
protein intake and lymphoid tissue involution was defined. Generally, the deficiencies of
energy, proteins, iron, iodine, vitamin A, zinc and calcium are the most common. It is
estimated that every third person is being affected globally. Prolonged hypercaloric intake
and resulting obesity could also exhibit immunocompromising effects through inflammation
and hyperactivation of the immune system. The negative impact on the immune system
could also be provoked by intense physical activity, infective agents, and emotional stress., Iako se stručna javnost slaže da se odgovarajući unos nutrijenata može obezbediti
dobro izbalansiranom ishranom, u opštoj populaciji su zastupljeni različiti režimi ishrane
koji u potpunosti ne slede preporuke relevantnih tela. Sa druge strane, nutritivni status je u
bliskoj vezi sa imunskim sistemom. Naime, nedovoljan kalorijski unos ili nedostatak nekog
nutrijenta prvenstveno može dovesti do slabljenja imunskog odgovora. Važnu ulogu u
funkciji imunskog sistema ima i gastrointestinalni trakt koji predstavlja mesto apsopcije
nutrijenata, ali i imunološke odbrane organizma. Najčešć i uzrok imunodeficijencije u svetu je
pothranjenost. i to kod čak 50% stanovništva u zemljama trećeg sveta. Pothranjenost dovodi
do poremećaja i urođenog i stečenog imunskog odgovora. Imajući u vidu ove činjenice, jasno
se nameće zaključak da dugotrajni režimi smanjenog kalorijskog unosa mogu ispoljiti sličan
efekat. Nutritivna imunologija je relativno mlada naučna disciplina koja se bavi ovom
problematikom, a šezdesetih godina izlazi monografija Svetske zdravstvene organizacije na
ovu temu. Sedamdesetih je uspostavljena jasna veza izmedju proteinske malnutricije i
involucije limfoidnog tkiva, pa i timusa. Globalno, među najzastupljenijijim deficitima su
deficit energetskog unosa, proteina, gvožđa, joda, vitamina A, D, cinka i kalcijuma, a procena
je da je svaka treća osoba u svetu pogođena nekim od nutritivnih deficita. Dugotrajan
prekomeran kalorijski unos kao i posledična gojaznost, takođe mogu ispoljiti
imunokompromitujući efekat i to kroz inflamaciju, kao i hiperaktivaciju imunskog odgovora.
Negativan efekat na imunski sistem mogu imati i veoma intenzivan fizički napor, kao i
psihički stress, i različiti infektivni agensi.",
publisher = "Savez farmaceutskih udruženja Srbije (SFUS)",
journal = "Arhiv za farmaciju",
title = "Influence of various dietary regimes upon immunity, Uticaj različitih dijetarnih režima na imunitet",
volume = "72",
number = "4 suplement",
pages = "S11-S12",
url = "https://hdl.handle.net/21.15107/rcub_farfar_4439"
}
Đorđević, B.,& Ivanović, N.. (2022). Influence of various dietary regimes upon immunity. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije (SFUS)., 72(4 suplement), S11-S12.
https://hdl.handle.net/21.15107/rcub_farfar_4439
Đorđević B, Ivanović N. Influence of various dietary regimes upon immunity. in Arhiv za farmaciju. 2022;72(4 suplement):S11-S12.
https://hdl.handle.net/21.15107/rcub_farfar_4439 .
Đorđević, Brižita, Ivanović, Nevena, "Influence of various dietary regimes upon immunity" in Arhiv za farmaciju, 72, no. 4 suplement (2022):S11-S12,
https://hdl.handle.net/21.15107/rcub_farfar_4439 .

Nutraceuticals in prevention and management of COVID-19

Đuričić, Ivana; Zrnić-Ćirić, Milica; Vidović, Bojana; Todorović, Vanja; Dabetić, Nevena; Ivanović, Nevena

(Društvo za ishranu Srbije, Beograd, 2021)

TY  - JOUR
AU  - Đuričić, Ivana
AU  - Zrnić-Ćirić, Milica
AU  - Vidović, Bojana
AU  - Todorović, Vanja
AU  - Dabetić, Nevena
AU  - Ivanović, Nevena
PY  - 2021
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5375
AB  - The immune system defends the host from many pathogen-
ic microorganisms such as viruses, bacteria, parasites and
fungi, including a large number of specific cell types, inter-
related molecules, and biological responses. Due to infec-
tions, heightened immune system activity is accompanied
by expanded metabolic activities, requiring appropriate
energy supply, precursors for biosynthesis and regulatory
molecules. Numerous vitamins and minerals play a crucial
role in supporting body’s immunity and fighting against
viral infections. Other bioactive compounds like omega-3
fatty acids, probiotics and antioxidants (alpha-lipoic acid,
quercetin) are also important in the immune response. CO-
VID-19 may develop mild symptoms to severe damage of
the respiratory epithelium followed by a cytokine storm.
Many studies show that vitamin C, vitamin D, zinc and selenium are critical in defending against SARS-CoV-2 infection.
Intestinal dysbiosis is a feature of many infectious diseases, including COVID-19, so dietary approaches to establishing a
healthy microbiota are essential for improving immune function. This paper reviews the data on the roles and potential
effectiveness of selected nutraceuticals in the prevention and treatment of COVID-19.
AB  - Imunski sistem štiti organizam od brojnih patogena (bakterija, virusa, gljivica, parazita) uključujući veliki broj specijalizovanih tipova ćelija, komunikacionih molekula i
funkcionalnih odgovora. Pojačana aktivnost imunskog si
stema usled infekcija praćena je povećanim metaboličkim
aktivnostima, što zahteva izvore energije, supstrate za biosintezu i regulatorne molekule. Brojni vitamini i minerali
imaju ključnu ulogu u podršci imunskom sistemu i smanjenju rizika od infekcija. Ostale bioaktivne komponente kao omega-3 masne kiseline, probiotici i antioksidansi (alfa-lipoinska kiselina, kvercetin) takođe su od značaja u imunološkom
odgovoru. COVID-19 karakterišu kliničke slike od blagih simptoma do teške infekcije respiratornog epitela praćene citokinskom olujom. Pokazano je da starije osobe sa hroničnim bolestima imaju smanjenu aktivnost odbrambenog sistema
i neadekvatan nutritivni status, zbog čega postoji veći rizik za pojavu fatalnih ishoda. Ispitivanja ukazuju da su vitamin
C, vitamin D, cink i selen posebno važni u odbrani od infekcije SARS-CoV-2. Disbioza creva je karakteristika mnogih zaraznih bolesti uključujući COVID-19, zato su dijetetski pristupi za uspostavljanje zdrave mikrobiote važni u poboljšanju
imunoloških funkcija. U ovom radu prikazan je pregled literature o ulozi i potencijalnoj primeni odabranih nutraceutika u
prevenciji i tretmanu COVID-19.
PB  - Društvo za ishranu Srbije, Beograd
T2  - Hrana i ishrana
T1  - Nutraceuticals in prevention and management of COVID-19
T1  - Nutraceutici u prevenciji i tretmanu COVID-19
VL  - 62
IS  - 2
SP  - 7
EP  - 14
DO  - 10.5937/hraIsh2102007D
ER  - 
@article{
author = "Đuričić, Ivana and Zrnić-Ćirić, Milica and Vidović, Bojana and Todorović, Vanja and Dabetić, Nevena and Ivanović, Nevena",
year = "2021",
abstract = "The immune system defends the host from many pathogen-
ic microorganisms such as viruses, bacteria, parasites and
fungi, including a large number of specific cell types, inter-
related molecules, and biological responses. Due to infec-
tions, heightened immune system activity is accompanied
by expanded metabolic activities, requiring appropriate
energy supply, precursors for biosynthesis and regulatory
molecules. Numerous vitamins and minerals play a crucial
role in supporting body’s immunity and fighting against
viral infections. Other bioactive compounds like omega-3
fatty acids, probiotics and antioxidants (alpha-lipoic acid,
quercetin) are also important in the immune response. CO-
VID-19 may develop mild symptoms to severe damage of
the respiratory epithelium followed by a cytokine storm.
Many studies show that vitamin C, vitamin D, zinc and selenium are critical in defending against SARS-CoV-2 infection.
Intestinal dysbiosis is a feature of many infectious diseases, including COVID-19, so dietary approaches to establishing a
healthy microbiota are essential for improving immune function. This paper reviews the data on the roles and potential
effectiveness of selected nutraceuticals in the prevention and treatment of COVID-19., Imunski sistem štiti organizam od brojnih patogena (bakterija, virusa, gljivica, parazita) uključujući veliki broj specijalizovanih tipova ćelija, komunikacionih molekula i
funkcionalnih odgovora. Pojačana aktivnost imunskog si
stema usled infekcija praćena je povećanim metaboličkim
aktivnostima, što zahteva izvore energije, supstrate za biosintezu i regulatorne molekule. Brojni vitamini i minerali
imaju ključnu ulogu u podršci imunskom sistemu i smanjenju rizika od infekcija. Ostale bioaktivne komponente kao omega-3 masne kiseline, probiotici i antioksidansi (alfa-lipoinska kiselina, kvercetin) takođe su od značaja u imunološkom
odgovoru. COVID-19 karakterišu kliničke slike od blagih simptoma do teške infekcije respiratornog epitela praćene citokinskom olujom. Pokazano je da starije osobe sa hroničnim bolestima imaju smanjenu aktivnost odbrambenog sistema
i neadekvatan nutritivni status, zbog čega postoji veći rizik za pojavu fatalnih ishoda. Ispitivanja ukazuju da su vitamin
C, vitamin D, cink i selen posebno važni u odbrani od infekcije SARS-CoV-2. Disbioza creva je karakteristika mnogih zaraznih bolesti uključujući COVID-19, zato su dijetetski pristupi za uspostavljanje zdrave mikrobiote važni u poboljšanju
imunoloških funkcija. U ovom radu prikazan je pregled literature o ulozi i potencijalnoj primeni odabranih nutraceutika u
prevenciji i tretmanu COVID-19.",
publisher = "Društvo za ishranu Srbije, Beograd",
journal = "Hrana i ishrana",
title = "Nutraceuticals in prevention and management of COVID-19, Nutraceutici u prevenciji i tretmanu COVID-19",
volume = "62",
number = "2",
pages = "7-14",
doi = "10.5937/hraIsh2102007D"
}
Đuričić, I., Zrnić-Ćirić, M., Vidović, B., Todorović, V., Dabetić, N.,& Ivanović, N.. (2021). Nutraceuticals in prevention and management of COVID-19. in Hrana i ishrana
Društvo za ishranu Srbije, Beograd., 62(2), 7-14.
https://doi.org/10.5937/hraIsh2102007D
Đuričić I, Zrnić-Ćirić M, Vidović B, Todorović V, Dabetić N, Ivanović N. Nutraceuticals in prevention and management of COVID-19. in Hrana i ishrana. 2021;62(2):7-14.
doi:10.5937/hraIsh2102007D .
Đuričić, Ivana, Zrnić-Ćirić, Milica, Vidović, Bojana, Todorović, Vanja, Dabetić, Nevena, Ivanović, Nevena, "Nutraceuticals in prevention and management of COVID-19" in Hrana i ishrana, 62, no. 2 (2021):7-14,
https://doi.org/10.5937/hraIsh2102007D . .
2