TY  - JOUR
AU  - Francuski, Bojana M.
AU  - Ivković, Branka
AU  - Stojanović, I
AU  - Vladimirov, S
AU  - Francuski, Đorđe
PY  - 2012
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1800
AB  - In the title compound, C16H11F3O 2, the -pyran-one ring adopts an envelope conformation with the chiral C atom standing out of the ring plane. In the crystal, molecules are linked by C - H⋯O and C - H⋯F inter-actions.
PB  - International Union of Crystallography
T2  - Acta Crystallographica Section E: Structure Reports Online
T1  - 2-[2-(Trifluoromethyl)phenyl]-2H-1-benzopyran-4(3H)-one
VL  - 68
IS  - 5
DO  - 10.1107/S160053681201687X
ER  - 

@article{
author = "Francuski, Bojana M. and Ivković, Branka and Stojanović, I and Vladimirov, S and Francuski, Đorđe",
year = "2012",
abstract = "In the title compound, C16H11F3O 2, the -pyran-one ring adopts an envelope conformation with the chiral C atom standing out of the ring plane. In the crystal, molecules are linked by C - H⋯O and C - H⋯F inter-actions.",
publisher = "International Union of Crystallography",
journal = "Acta Crystallographica Section E: Structure Reports Online",
title = "2-[2-(Trifluoromethyl)phenyl]-2H-1-benzopyran-4(3H)-one",
volume = "68",
number = "5",
doi = "10.1107/S160053681201687X"
}

Francuski, B. M., Ivković, B., Stojanović, I., Vladimirov, S.,& Francuski, Đ.. (2012). 2-[2-(Trifluoromethyl)phenyl]-2H-1-benzopyran-4(3H)-one. in Acta Crystallographica Section E: Structure Reports Online
International Union of Crystallography., 68(5).
https://doi.org/10.1107/S160053681201687X

Francuski BM, Ivković B, Stojanović I, Vladimirov S, Francuski Đ. 2-[2-(Trifluoromethyl)phenyl]-2H-1-benzopyran-4(3H)-one. in Acta Crystallographica Section E: Structure Reports Online. 2012;68(5).
doi:10.1107/S160053681201687X .

Francuski, Bojana M., Ivković, Branka, Stojanović, I, Vladimirov, S, Francuski, Đorđe, "2-[2-(Trifluoromethyl)phenyl]-2H-1-benzopyran-4(3H)-one" in Acta Crystallographica Section E: Structure Reports Online, 68, no. 5 (2012),
https://doi.org/10.1107/S160053681201687X . .

TY  - JOUR
AU  - Stojanović, J
AU  - Marinković, Valentina
AU  - Vladimirov, S
AU  - Veličković, D.
AU  - Sibinović, Predrag
PY  - 2005
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/623
AB  - A reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed for separation of carvedilol and its impurities from Karvileks tablets. The best separation was achieved on a 100 mm x 4.6 mm, 5 mu m particle size, Chromolit RP 8e column. Use of acetonitrile-water, 45:55 (v/v), adjusted to pH 2.5 with formic acid, as mobile phase at a flow rate of 0.5 mL min(-1) enabled acceptable resolution of carvedilol, in large excess, from possible impurities, in a short elution time. UV detection was performed at 280 nm. Linearity, accuracy, precision, selectivity, and robustness were validated and found to be satisfactory. Overall, the proposed method was found to be highly sensitive, suitable, and accurate for quantitative determination of carvedilol and its impurities in dosage forms and in raw materials.
PB  - Vieweg, Wiesbaden
T2  - Chromatographia
T1  - Determination of carvedilol and its impurities in pharmaceuticals
VL  - 62
IS  - 9-10
SP  - 539
EP  - 542
DO  - 10.1365/s10337-005-0656-y
ER  - 

@article{
author = "Stojanović, J and Marinković, Valentina and Vladimirov, S and Veličković, D. and Sibinović, Predrag",
year = "2005",
abstract = "A reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed for separation of carvedilol and its impurities from Karvileks tablets. The best separation was achieved on a 100 mm x 4.6 mm, 5 mu m particle size, Chromolit RP 8e column. Use of acetonitrile-water, 45:55 (v/v), adjusted to pH 2.5 with formic acid, as mobile phase at a flow rate of 0.5 mL min(-1) enabled acceptable resolution of carvedilol, in large excess, from possible impurities, in a short elution time. UV detection was performed at 280 nm. Linearity, accuracy, precision, selectivity, and robustness were validated and found to be satisfactory. Overall, the proposed method was found to be highly sensitive, suitable, and accurate for quantitative determination of carvedilol and its impurities in dosage forms and in raw materials.",
publisher = "Vieweg, Wiesbaden",
journal = "Chromatographia",
title = "Determination of carvedilol and its impurities in pharmaceuticals",
volume = "62",
number = "9-10",
pages = "539-542",
doi = "10.1365/s10337-005-0656-y"
}

Stojanović, J., Marinković, V., Vladimirov, S., Veličković, D.,& Sibinović, P.. (2005). Determination of carvedilol and its impurities in pharmaceuticals. in Chromatographia
Vieweg, Wiesbaden., 62(9-10), 539-542.
https://doi.org/10.1365/s10337-005-0656-y

Stojanović J, Marinković V, Vladimirov S, Veličković D, Sibinović P. Determination of carvedilol and its impurities in pharmaceuticals. in Chromatographia. 2005;62(9-10):539-542.
doi:10.1365/s10337-005-0656-y .

Stojanović, J, Marinković, Valentina, Vladimirov, S, Veličković, D., Sibinović, Predrag, "Determination of carvedilol and its impurities in pharmaceuticals" in Chromatographia, 62, no. 9-10 (2005):539-542,
https://doi.org/10.1365/s10337-005-0656-y . .

TY  - JOUR
AU  - Brborić, Jasmina
AU  - Vladimirov, S
AU  - Jovanović, MS
AU  - Dogović, N
PY  - 2004
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/523
AB  - The synthesis and characterization of N-[2-[[4-iodo-2,6-bis(1-methylethyl)phenyl]amino]-2-oxoethyl]-N-(carboxymethyl)glycine and N-[2-[(4-iodo-2,6-diethylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine is presented, as well as a modified and improved synthesis of N-[2-[(2,4-diiodo-6-methylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine. These compounds are new agents for hepatobiliary imaging.
PB  - Springer Wien, Vienna
T2  - Monatshefte für Chemie Chemical Monthly
T1  - The synthesis of novel iodinated iminodiacetic acid analogues as hepatobiliary imaging agents
VL  - 135
IS  - 8
SP  - 1009
EP  - 1014
DO  - 10.1007/s00706-004-0174-x
ER  - 

@article{
author = "Brborić, Jasmina and Vladimirov, S and Jovanović, MS and Dogović, N",
year = "2004",
abstract = "The synthesis and characterization of N-[2-[[4-iodo-2,6-bis(1-methylethyl)phenyl]amino]-2-oxoethyl]-N-(carboxymethyl)glycine and N-[2-[(4-iodo-2,6-diethylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine is presented, as well as a modified and improved synthesis of N-[2-[(2,4-diiodo-6-methylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine. These compounds are new agents for hepatobiliary imaging.",
publisher = "Springer Wien, Vienna",
journal = "Monatshefte für Chemie Chemical Monthly",
title = "The synthesis of novel iodinated iminodiacetic acid analogues as hepatobiliary imaging agents",
volume = "135",
number = "8",
pages = "1009-1014",
doi = "10.1007/s00706-004-0174-x"
}

Brborić, J., Vladimirov, S., Jovanović, M.,& Dogović, N.. (2004). The synthesis of novel iodinated iminodiacetic acid analogues as hepatobiliary imaging agents. in Monatshefte für Chemie Chemical Monthly
Springer Wien, Vienna., 135(8), 1009-1014.
https://doi.org/10.1007/s00706-004-0174-x

Brborić J, Vladimirov S, Jovanović M, Dogović N. The synthesis of novel iodinated iminodiacetic acid analogues as hepatobiliary imaging agents. in Monatshefte für Chemie Chemical Monthly. 2004;135(8):1009-1014.
doi:10.1007/s00706-004-0174-x .

Brborić, Jasmina, Vladimirov, S, Jovanović, MS, Dogović, N, "The synthesis of novel iodinated iminodiacetic acid analogues as hepatobiliary imaging agents" in Monatshefte für Chemie Chemical Monthly, 135, no. 8 (2004):1009-1014,
https://doi.org/10.1007/s00706-004-0174-x . .

TY  - JOUR
AU  - Čakar, Mira
AU  - Popović, Gordana
AU  - Vladimirov, Sote
PY  - 2004
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/524
AB  - A simple and reliable HPTLC method has been developed for simultaneous determination of antimycotics (bifonazole and econazole nitrate) and preservatives (methyl- and propylparaben) in medicinal creams. Chromatography was performed on silica gel plates with ethyl acetate-n-hexane-methanol-ammonia-diethylamine, 0.5 + 4 + 0.8 + 0.4 + 2 (v/v) as mobile phase. Chromatographic zones corresponding to spots of econazole nitrate, bifonazole, and parabens were scanned in reflectance/absorbance mode at lambda = 230, 250, and 300 nm, respectively. The method was successfully applied to simultaneous determination of the compounds in commercially available pharmaceuticals.
PB  - Springer Nature
T2  - Journal of Planar Chromatography - Modern TLC
T1  - Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams
VL  - 17
IS  - 3
SP  - 177
EP  - 180
DO  - 10.1556/JPC.17.2004.3.4
ER  - 

@article{
author = "Čakar, Mira and Popović, Gordana and Vladimirov, Sote",
year = "2004",
abstract = "A simple and reliable HPTLC method has been developed for simultaneous determination of antimycotics (bifonazole and econazole nitrate) and preservatives (methyl- and propylparaben) in medicinal creams. Chromatography was performed on silica gel plates with ethyl acetate-n-hexane-methanol-ammonia-diethylamine, 0.5 + 4 + 0.8 + 0.4 + 2 (v/v) as mobile phase. Chromatographic zones corresponding to spots of econazole nitrate, bifonazole, and parabens were scanned in reflectance/absorbance mode at lambda = 230, 250, and 300 nm, respectively. The method was successfully applied to simultaneous determination of the compounds in commercially available pharmaceuticals.",
publisher = "Springer Nature",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams",
volume = "17",
number = "3",
pages = "177-180",
doi = "10.1556/JPC.17.2004.3.4"
}

Čakar, M., Popović, G.,& Vladimirov, S.. (2004). Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams. in Journal of Planar Chromatography - Modern TLC
Springer Nature., 17(3), 177-180.
https://doi.org/10.1556/JPC.17.2004.3.4

Čakar M, Popović G, Vladimirov S. Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams. in Journal of Planar Chromatography - Modern TLC. 2004;17(3):177-180.
doi:10.1556/JPC.17.2004.3.4 .

Čakar, Mira, Popović, Gordana, Vladimirov, Sote, "Simultaneous HPTLC determination of imidazole antimycotics and parabens in creams" in Journal of Planar Chromatography - Modern TLC, 17, no. 3 (2004):177-180,
https://doi.org/10.1556/JPC.17.2004.3.4 . .

TY  - JOUR
AU  - Velikinac, I
AU  - Čudina, Olivera
AU  - Janković, I
AU  - Agbaba, Danica
AU  - Vladimirov, S
PY  - 2004
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/554
AB  - A capillary zone electrophoresis (CZE) and a high-performance liquid chromatography (HPLC) method have been developed for identification and determination of ketoconazole, an imidazole antifungal, in pharmaceutical preparations. The suitabilities of both methods for quantitative determination of ketoconazole were approved through validation specification such as linearity, precision, accuracy, limit of detection and quantification. The proposed methods were used for determination of ketoconazole in commercial pharmaceutical dosage forms (tablets and creams). Under described conditions, CZE method is more selective, while the HPLC method is more sensitive. Both methods are rapid (t R (CZE)=5.14 min and t R (HPLC)=2.66 min), which is important for routine application. However, the HPLC method provides a repeatability of the quantitative analysis of ketoconazole in drug formulations below 1.5% relative standard deviation (R.S.D), while the repeatability of the CZE method is in the order of 2-3% R.S.D.
PB  - Elsevier Masson SAS
T2  - Farmaco
T1  - Comparison of capillary zone electrophoresis and high performance liquid chromatography methods for quantitative determination of ketoconazole in drug formulations
VL  - 59
IS  - 5
SP  - 419
EP  - 424
DO  - 10.1016/j.farmac.2003.11.019
ER  - 

@article{
author = "Velikinac, I and Čudina, Olivera and Janković, I and Agbaba, Danica and Vladimirov, S",
year = "2004",
abstract = "A capillary zone electrophoresis (CZE) and a high-performance liquid chromatography (HPLC) method have been developed for identification and determination of ketoconazole, an imidazole antifungal, in pharmaceutical preparations. The suitabilities of both methods for quantitative determination of ketoconazole were approved through validation specification such as linearity, precision, accuracy, limit of detection and quantification. The proposed methods were used for determination of ketoconazole in commercial pharmaceutical dosage forms (tablets and creams). Under described conditions, CZE method is more selective, while the HPLC method is more sensitive. Both methods are rapid (t R (CZE)=5.14 min and t R (HPLC)=2.66 min), which is important for routine application. However, the HPLC method provides a repeatability of the quantitative analysis of ketoconazole in drug formulations below 1.5% relative standard deviation (R.S.D), while the repeatability of the CZE method is in the order of 2-3% R.S.D.",
publisher = "Elsevier Masson SAS",
journal = "Farmaco",
title = "Comparison of capillary zone electrophoresis and high performance liquid chromatography methods for quantitative determination of ketoconazole in drug formulations",
volume = "59",
number = "5",
pages = "419-424",
doi = "10.1016/j.farmac.2003.11.019"
}

Velikinac, I., Čudina, O., Janković, I., Agbaba, D.,& Vladimirov, S.. (2004). Comparison of capillary zone electrophoresis and high performance liquid chromatography methods for quantitative determination of ketoconazole in drug formulations. in Farmaco
Elsevier Masson SAS., 59(5), 419-424.
https://doi.org/10.1016/j.farmac.2003.11.019

Velikinac I, Čudina O, Janković I, Agbaba D, Vladimirov S. Comparison of capillary zone electrophoresis and high performance liquid chromatography methods for quantitative determination of ketoconazole in drug formulations. in Farmaco. 2004;59(5):419-424.
doi:10.1016/j.farmac.2003.11.019 .

Velikinac, I, Čudina, Olivera, Janković, I, Agbaba, Danica, Vladimirov, S, "Comparison of capillary zone electrophoresis and high performance liquid chromatography methods for quantitative determination of ketoconazole in drug formulations" in Farmaco, 59, no. 5 (2004):419-424,
https://doi.org/10.1016/j.farmac.2003.11.019 . .

TY  - JOUR
AU  - Živanović, L
AU  - Ivanović, I
AU  - Vladimirov, S
AU  - Zečević, Mira
PY  - 2004
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/535
AB  - The optimal chromatographic conditions for the separation of the syn- and anti-geometric isomers of cefuroxime axetil applying RP-HPLC and micellar liquid chromatography (MLC) methods were investigated. The possibility to separate diastereoisomers of syn- and anti-cefuroxime axetil was observed. Investigations were performed using three columns, two classical silicas and one with hybrid particle technology. Three aqueous-organic and one micellar mobile phases were used. The best results were achieved using micellar mobile phase. Optimization study was performed using different micellar mobile phases. MLC method is sensitive and applicable in purity and stability testing.
PB  - Elsevier Science BV, Amsterdam
T2  - Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences
T1  - Investigation of chromatographic conditions for the separation of cefuroxime axetil and its geometric isomer
VL  - 800
IS  - 1-2
SP  - 175
EP  - 179
DO  - 10.1016/j.jchromb.2003.08.046
ER  - 

@article{
author = "Živanović, L and Ivanović, I and Vladimirov, S and Zečević, Mira",
year = "2004",
abstract = "The optimal chromatographic conditions for the separation of the syn- and anti-geometric isomers of cefuroxime axetil applying RP-HPLC and micellar liquid chromatography (MLC) methods were investigated. The possibility to separate diastereoisomers of syn- and anti-cefuroxime axetil was observed. Investigations were performed using three columns, two classical silicas and one with hybrid particle technology. Three aqueous-organic and one micellar mobile phases were used. The best results were achieved using micellar mobile phase. Optimization study was performed using different micellar mobile phases. MLC method is sensitive and applicable in purity and stability testing.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences",
title = "Investigation of chromatographic conditions for the separation of cefuroxime axetil and its geometric isomer",
volume = "800",
number = "1-2",
pages = "175-179",
doi = "10.1016/j.jchromb.2003.08.046"
}

Živanović, L., Ivanović, I., Vladimirov, S.,& Zečević, M.. (2004). Investigation of chromatographic conditions for the separation of cefuroxime axetil and its geometric isomer. in Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences
Elsevier Science BV, Amsterdam., 800(1-2), 175-179.
https://doi.org/10.1016/j.jchromb.2003.08.046

Živanović L, Ivanović I, Vladimirov S, Zečević M. Investigation of chromatographic conditions for the separation of cefuroxime axetil and its geometric isomer. in Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 2004;800(1-2):175-179.
doi:10.1016/j.jchromb.2003.08.046 .

Živanović, L, Ivanović, I, Vladimirov, S, Zečević, Mira, "Investigation of chromatographic conditions for the separation of cefuroxime axetil and its geometric isomer" in Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 800, no. 1-2 (2004):175-179,
https://doi.org/10.1016/j.jchromb.2003.08.046 . .

TY  - JOUR
AU  - Nikolić, N
AU  - Veselinović, D
AU  - Vladimirov, S
AU  - Karljiković-Rajić, Katarina
AU  - Lingeman, H
PY  - 2004
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/534
AB  - Tc-99m(V)-d,l-HM-PAO complex is well-known radiopharmaceutical for regional cerebral blood flow imaging. The proposed modifications in exametazime, hexamethylpropyleneamine oxime (HM-PAO) (4,8-diaza-3,6,6,9-tetramethylundecane-2,10-dione bisoxime) synthesis, for reduction of intermediary reactant diiminebisoxime (DI) (4,8-diaza-3,6,6,9-tetramethylundecane-3,8-diene-2,10-dione bisoxime) concerned two reductants (NaBH4 and KBH4), two solvents (ethanol and 2-propanol), and three mole ratios of reactant/reductants (1:1, 1:1.5, and 1:2). The simultaneous analysis of diastereo-enantiomeric HM-PAO content, as well as the content of starting DI, in different reduction mixtures were pet-formed using chiral ligand-exchange chromatography (CLEC). The separation of the samples of investigated reduction mixtures, obtained in the second step of HM-PAO synthesis, has been accomplished by using an achiral sorbent (RP- 18) and a chiral mobile phase (CMP) containing copper(II) complex with N,N-ditnethyl-L-phenylalanine (L-DM-PhA) as initial complex for CLEC. With 12 different reduction conditions, the obtained ratios of diastereoisomers d,l-HM-PAO: mesa-HM-PAO varied from 69.2:30.8 to 15.9:84.1, in comparison to the reduction in routine synthesis of HM-PAO which gives an equal mixture of diastereoisomers. The ternary mixed complexes formation recorded spectrophotometrically on addition of HM-PAO or DI to the mobile phase with binary complex Cu(L-DM-PhA)(2), due to the evidence of bathochromic shift of 46 nm for lambda(max) with significant difference in absorptivity contributes to separation mechanism.
PB  - Elsevier Science BV, Amsterdam
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Chiral ligand-exchange chromatography as the screening method for proposed modifications in exametazime synthesis to enhance diastereoselectivity
VL  - 34
IS  - 2
SP  - 285
EP  - 293
DO  - 10.1016/S0731-7085(03)00551-X
ER  - 

@article{
author = "Nikolić, N and Veselinović, D and Vladimirov, S and Karljiković-Rajić, Katarina and Lingeman, H",
year = "2004",
abstract = "Tc-99m(V)-d,l-HM-PAO complex is well-known radiopharmaceutical for regional cerebral blood flow imaging. The proposed modifications in exametazime, hexamethylpropyleneamine oxime (HM-PAO) (4,8-diaza-3,6,6,9-tetramethylundecane-2,10-dione bisoxime) synthesis, for reduction of intermediary reactant diiminebisoxime (DI) (4,8-diaza-3,6,6,9-tetramethylundecane-3,8-diene-2,10-dione bisoxime) concerned two reductants (NaBH4 and KBH4), two solvents (ethanol and 2-propanol), and three mole ratios of reactant/reductants (1:1, 1:1.5, and 1:2). The simultaneous analysis of diastereo-enantiomeric HM-PAO content, as well as the content of starting DI, in different reduction mixtures were pet-formed using chiral ligand-exchange chromatography (CLEC). The separation of the samples of investigated reduction mixtures, obtained in the second step of HM-PAO synthesis, has been accomplished by using an achiral sorbent (RP- 18) and a chiral mobile phase (CMP) containing copper(II) complex with N,N-ditnethyl-L-phenylalanine (L-DM-PhA) as initial complex for CLEC. With 12 different reduction conditions, the obtained ratios of diastereoisomers d,l-HM-PAO: mesa-HM-PAO varied from 69.2:30.8 to 15.9:84.1, in comparison to the reduction in routine synthesis of HM-PAO which gives an equal mixture of diastereoisomers. The ternary mixed complexes formation recorded spectrophotometrically on addition of HM-PAO or DI to the mobile phase with binary complex Cu(L-DM-PhA)(2), due to the evidence of bathochromic shift of 46 nm for lambda(max) with significant difference in absorptivity contributes to separation mechanism.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Chiral ligand-exchange chromatography as the screening method for proposed modifications in exametazime synthesis to enhance diastereoselectivity",
volume = "34",
number = "2",
pages = "285-293",
doi = "10.1016/S0731-7085(03)00551-X"
}

Nikolić, N., Veselinović, D., Vladimirov, S., Karljiković-Rajić, K.,& Lingeman, H.. (2004). Chiral ligand-exchange chromatography as the screening method for proposed modifications in exametazime synthesis to enhance diastereoselectivity. in Journal of Pharmaceutical and Biomedical Analysis
Elsevier Science BV, Amsterdam., 34(2), 285-293.
https://doi.org/10.1016/S0731-7085(03)00551-X

Nikolić N, Veselinović D, Vladimirov S, Karljiković-Rajić K, Lingeman H. Chiral ligand-exchange chromatography as the screening method for proposed modifications in exametazime synthesis to enhance diastereoselectivity. in Journal of Pharmaceutical and Biomedical Analysis. 2004;34(2):285-293.
doi:10.1016/S0731-7085(03)00551-X .

Nikolić, N, Veselinović, D, Vladimirov, S, Karljiković-Rajić, Katarina, Lingeman, H, "Chiral ligand-exchange chromatography as the screening method for proposed modifications in exametazime synthesis to enhance diastereoselectivity" in Journal of Pharmaceutical and Biomedical Analysis, 34, no. 2 (2004):285-293,
https://doi.org/10.1016/S0731-7085(03)00551-X . .

TY  - JOUR
AU  - Jovanović, MS
AU  - Popović, Gordana
AU  - Kapetanović, Vera
AU  - Orlić, M
AU  - Vladimirov, S
PY  - 2004
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/516
AB  - In order to develop a radiopharmaceutical for hepatobiliary scintigraphy with better hepatobiliary properties new ligand for complexation of Tc-99m, 4-iodo-2,6-dimethylphenylcarbamoylmethyl iminodiacetic acid (METHYLIODIDA), was synthesized. Acid-base equilibria of METHYLIODIDA were studied potentiometrically, because these data are important for determination of complex formation conditions. It was established that METHYLIODIDA undergoes a complex acid-base equilibrium due to its zwitterionic nature and four proton-binding sites. The stoichiometric ionization constants were determined at 25 degreesC and constant ionic strength 0.1 M (NaClO4): pK(1) = 1.7 +/- 0.1; pK(2) = 2.44 +/- 0.07; pK(3) = 6.29 +/- 0.02 and pK(4) = 10.91 +/- 0.06, respectively.
PB  - Elsevier Science BV, Amsterdam
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Determination of the ionization constants of 4-iodo-2,6-dimethylphenylcarbamoylmethyl iminodiacetic acid
VL  - 35
IS  - 5
SP  - 1257
EP  - 1261
DO  - 10.1016/j.jpba.2004.03.009
ER  - 

@article{
author = "Jovanović, MS and Popović, Gordana and Kapetanović, Vera and Orlić, M and Vladimirov, S",
year = "2004",
abstract = "In order to develop a radiopharmaceutical for hepatobiliary scintigraphy with better hepatobiliary properties new ligand for complexation of Tc-99m, 4-iodo-2,6-dimethylphenylcarbamoylmethyl iminodiacetic acid (METHYLIODIDA), was synthesized. Acid-base equilibria of METHYLIODIDA were studied potentiometrically, because these data are important for determination of complex formation conditions. It was established that METHYLIODIDA undergoes a complex acid-base equilibrium due to its zwitterionic nature and four proton-binding sites. The stoichiometric ionization constants were determined at 25 degreesC and constant ionic strength 0.1 M (NaClO4): pK(1) = 1.7 +/- 0.1; pK(2) = 2.44 +/- 0.07; pK(3) = 6.29 +/- 0.02 and pK(4) = 10.91 +/- 0.06, respectively.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Determination of the ionization constants of 4-iodo-2,6-dimethylphenylcarbamoylmethyl iminodiacetic acid",
volume = "35",
number = "5",
pages = "1257-1261",
doi = "10.1016/j.jpba.2004.03.009"
}

Jovanović, M., Popović, G., Kapetanović, V., Orlić, M.,& Vladimirov, S.. (2004). Determination of the ionization constants of 4-iodo-2,6-dimethylphenylcarbamoylmethyl iminodiacetic acid. in Journal of Pharmaceutical and Biomedical Analysis
Elsevier Science BV, Amsterdam., 35(5), 1257-1261.
https://doi.org/10.1016/j.jpba.2004.03.009

Jovanović M, Popović G, Kapetanović V, Orlić M, Vladimirov S. Determination of the ionization constants of 4-iodo-2,6-dimethylphenylcarbamoylmethyl iminodiacetic acid. in Journal of Pharmaceutical and Biomedical Analysis. 2004;35(5):1257-1261.
doi:10.1016/j.jpba.2004.03.009 .

Jovanović, MS, Popović, Gordana, Kapetanović, Vera, Orlić, M, Vladimirov, S, "Determination of the ionization constants of 4-iodo-2,6-dimethylphenylcarbamoylmethyl iminodiacetic acid" in Journal of Pharmaceutical and Biomedical Analysis, 35, no. 5 (2004):1257-1261,
https://doi.org/10.1016/j.jpba.2004.03.009 . .

TY  - JOUR
AU  - Popović, Gordana
AU  - Čakar, Mira
AU  - Vučićević, Katarina
AU  - Vladimirov, S
AU  - Agbaba, Danica
PY  - 2004
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/479
AB  - HPTLC and HPLC methods have been established for separation and quantitative determination of econazole nitrate. HPTLC was performed on silica gel plates with n-butyl acetate-carbon tetrachloride-methanol-diethylamine, 3 + 6 + 2.5 + 0.5 (v/v), as mobile phase. Chromatographic zones, or spots, of econazole base and nitrate were used to quantify econazole nitrate. HPLC was performed on amino and C-8 columns with acetonitrile-water, 30 + 70 (v/v), pH 2.5 (adjusted with phosphoric acid), as a mobile phase. The chromatograms were characterized by single peaks of econazole (amino column) or nitrate (C-8 column). The methods were successfully used for determination of econazole nitrate in spray solution and vaginal pessaries.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography - Modern TLC
T1  - Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms
VL  - 17
IS  - 2
SP  - 109
EP  - 112
DO  - 10.1556/JPC.17.2004.2.5
ER  - 

@article{
author = "Popović, Gordana and Čakar, Mira and Vučićević, Katarina and Vladimirov, S and Agbaba, Danica",
year = "2004",
abstract = "HPTLC and HPLC methods have been established for separation and quantitative determination of econazole nitrate. HPTLC was performed on silica gel plates with n-butyl acetate-carbon tetrachloride-methanol-diethylamine, 3 + 6 + 2.5 + 0.5 (v/v), as mobile phase. Chromatographic zones, or spots, of econazole base and nitrate were used to quantify econazole nitrate. HPLC was performed on amino and C-8 columns with acetonitrile-water, 30 + 70 (v/v), pH 2.5 (adjusted with phosphoric acid), as a mobile phase. The chromatograms were characterized by single peaks of econazole (amino column) or nitrate (C-8 column). The methods were successfully used for determination of econazole nitrate in spray solution and vaginal pessaries.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms",
volume = "17",
number = "2",
pages = "109-112",
doi = "10.1556/JPC.17.2004.2.5"
}

Popović, G., Čakar, M., Vučićević, K., Vladimirov, S.,& Agbaba, D.. (2004). Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms. in Journal of Planar Chromatography - Modern TLC
Research Inst Medicinal Plants, Budakalasz., 17(2), 109-112.
https://doi.org/10.1556/JPC.17.2004.2.5

Popović G, Čakar M, Vučićević K, Vladimirov S, Agbaba D. Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms. in Journal of Planar Chromatography - Modern TLC. 2004;17(2):109-112.
doi:10.1556/JPC.17.2004.2.5 .

Popović, Gordana, Čakar, Mira, Vučićević, Katarina, Vladimirov, S, Agbaba, Danica, "Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms" in Journal of Planar Chromatography - Modern TLC, 17, no. 2 (2004):109-112,
https://doi.org/10.1556/JPC.17.2004.2.5 . .

TY  - JOUR
AU  - Marinković, Valentina
AU  - Agbaba, Danica
AU  - Karljiković-Rajić, Katarina
AU  - Vladimirov, S
AU  - Nedeljković, Jovan M.
PY  - 2003
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/438
AB  - The photochemical degradation of solid-state nisoldipine, 1,4-dihydropyridine calcium antagonist, was investigated under daylight and UV light conditions. Degradation products were identified by using the retention times of corresponding standards and quantified by high-performance liquid chromatographic method. The daylight illumination induced appearance of nitrosophenylpyridine, while formation of second degradation product, nitrophenylpyridine, was observed only upon UV light illumination. The photodegradation kinetics of solid-state nisoldipine under daylight and UV light illumination belongs to class of zero-order reactions. The rate constants of disappearance of nisoldipine upon illumination were determined for raw material as well as pharmaceuticals (tablets, film-tablets and capsules).
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Photochemical degradation of solid-state nisoldipine monitored by HPLC
VL  - 32
IS  - 4-5
SP  - 929
EP  - 935
DO  - 10.1016/S0731-7085(03)00194-8
ER  - 

@article{
author = "Marinković, Valentina and Agbaba, Danica and Karljiković-Rajić, Katarina and Vladimirov, S and Nedeljković, Jovan M.",
year = "2003",
abstract = "The photochemical degradation of solid-state nisoldipine, 1,4-dihydropyridine calcium antagonist, was investigated under daylight and UV light conditions. Degradation products were identified by using the retention times of corresponding standards and quantified by high-performance liquid chromatographic method. The daylight illumination induced appearance of nitrosophenylpyridine, while formation of second degradation product, nitrophenylpyridine, was observed only upon UV light illumination. The photodegradation kinetics of solid-state nisoldipine under daylight and UV light illumination belongs to class of zero-order reactions. The rate constants of disappearance of nisoldipine upon illumination were determined for raw material as well as pharmaceuticals (tablets, film-tablets and capsules).",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Photochemical degradation of solid-state nisoldipine monitored by HPLC",
volume = "32",
number = "4-5",
pages = "929-935",
doi = "10.1016/S0731-7085(03)00194-8"
}

Marinković, V., Agbaba, D., Karljiković-Rajić, K., Vladimirov, S.,& Nedeljković, J. M.. (2003). Photochemical degradation of solid-state nisoldipine monitored by HPLC. in Journal of Pharmaceutical and Biomedical Analysis
Pergamon-Elsevier Science Ltd, Oxford., 32(4-5), 929-935.
https://doi.org/10.1016/S0731-7085(03)00194-8

Marinković V, Agbaba D, Karljiković-Rajić K, Vladimirov S, Nedeljković JM. Photochemical degradation of solid-state nisoldipine monitored by HPLC. in Journal of Pharmaceutical and Biomedical Analysis. 2003;32(4-5):929-935.
doi:10.1016/S0731-7085(03)00194-8 .

Marinković, Valentina, Agbaba, Danica, Karljiković-Rajić, Katarina, Vladimirov, S, Nedeljković, Jovan M., "Photochemical degradation of solid-state nisoldipine monitored by HPLC" in Journal of Pharmaceutical and Biomedical Analysis, 32, no. 4-5 (2003):929-935,
https://doi.org/10.1016/S0731-7085(03)00194-8 . .

TY  - JOUR
AU  - Pavić, K
AU  - Čudina, Olivera
AU  - Agbaba, Danica
AU  - Vladimirov, S
PY  - 2003
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/416
AB  - This paper describes a simple, rapid, and reliable HPTLC procedure for the determination of cyproterone acetate and ethinylestradiol in tablets. Identification and determination were performed on 10 cm x 20 cm, LiChrospher silica gel 60 F-254 HPTLC plates with cyclohexane-ethyl acetate, 6 + 4 (nu/nu), as mobile phase. Calibration plots were established showing the dependence of response (peak area) on amount chromatographed. The ranges validated were 250-4000 ng (r = 0.9923) and 100-500 ng (r = 0.9996) for cyproterone acetate and ethinylestradiol, respectively. The suitability of this HPTLC method for quantitative determination of the compounds was proved by validation of precision and accuracy. The method was used for determination of the compounds in commercial pharmaceutical dosage forms (Androcur 10 mg and Diane 35 tablets). The method is simple, reproducible, and accurate and can be used as a more effective option than other chromatographic techniques in routine quality control.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography - Modern TLC
T1  - Quantitative analysis of cyproterone acetate and ethinylestradiol in tablets by use of planar chromatography
VL  - 16
IS  - 1
SP  - 45
EP  - 47
DO  - 10.1556/JPC.16.2003.1.9
ER  - 

@article{
author = "Pavić, K and Čudina, Olivera and Agbaba, Danica and Vladimirov, S",
year = "2003",
abstract = "This paper describes a simple, rapid, and reliable HPTLC procedure for the determination of cyproterone acetate and ethinylestradiol in tablets. Identification and determination were performed on 10 cm x 20 cm, LiChrospher silica gel 60 F-254 HPTLC plates with cyclohexane-ethyl acetate, 6 + 4 (nu/nu), as mobile phase. Calibration plots were established showing the dependence of response (peak area) on amount chromatographed. The ranges validated were 250-4000 ng (r = 0.9923) and 100-500 ng (r = 0.9996) for cyproterone acetate and ethinylestradiol, respectively. The suitability of this HPTLC method for quantitative determination of the compounds was proved by validation of precision and accuracy. The method was used for determination of the compounds in commercial pharmaceutical dosage forms (Androcur 10 mg and Diane 35 tablets). The method is simple, reproducible, and accurate and can be used as a more effective option than other chromatographic techniques in routine quality control.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Quantitative analysis of cyproterone acetate and ethinylestradiol in tablets by use of planar chromatography",
volume = "16",
number = "1",
pages = "45-47",
doi = "10.1556/JPC.16.2003.1.9"
}

Pavić, K., Čudina, O., Agbaba, D.,& Vladimirov, S.. (2003). Quantitative analysis of cyproterone acetate and ethinylestradiol in tablets by use of planar chromatography. in Journal of Planar Chromatography - Modern TLC
Research Inst Medicinal Plants, Budakalasz., 16(1), 45-47.
https://doi.org/10.1556/JPC.16.2003.1.9

Pavić K, Čudina O, Agbaba D, Vladimirov S. Quantitative analysis of cyproterone acetate and ethinylestradiol in tablets by use of planar chromatography. in Journal of Planar Chromatography - Modern TLC. 2003;16(1):45-47.
doi:10.1556/JPC.16.2003.1.9 .

Pavić, K, Čudina, Olivera, Agbaba, Danica, Vladimirov, S, "Quantitative analysis of cyproterone acetate and ethinylestradiol in tablets by use of planar chromatography" in Journal of Planar Chromatography - Modern TLC, 16, no. 1 (2003):45-47,
https://doi.org/10.1556/JPC.16.2003.1.9 . .

TY  - JOUR
AU  - Franeta, JT
AU  - Agbaba, Danica
AU  - Erić, Slavica
AU  - Pavkov, S
AU  - Aleksić, Mirjana

AU  - Vladimirov, S
PY  - 2002
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/320
AB  - This paper present a HPLC method for simultaneous determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets, using chromatographic system consisting a Bio Rad 18 01 solvent pump, Rheodine 71 25 injector and Bio Rad 18 01 UV-Vis Detector. Separation was achieved using Bio SiL HL C 18, 5 mum, 250 x 4.6 mm column. Mixture of acetonitrile-water (25:75 v/v) adjusted to pH 2.5 with phosphoric acid was used as a mobile phase at a flow rate of 2.0 ml(-1) min UV detection was at 207 nm range 0.01 AUFS. Under the same conditions it was possible to determine the level of salicylic acid. The chromatographic parameters such as retention times, capacity factor, peak asymmetry, selectivity factor and resolution factor was determined. The validation parameters: linearity (r > 0.998), intra-day precision (RSD: 0.36-1.89%) and inter-day precision (RSD: 0.58-2.18%), sensitivity (LOD: 9 x 10(-5)-1.7 x 10(-4) mg ml(-1) and LOQ: 2.5 x 10(-4)-5.6 x 10(-4) mg ml(-1)), accuracy (recoveries: 98.35-99.14%) and reproducibility (recovery values: 98.74-102.08% for acetylsalicylic acid, 99.93-102.11% for paracetamol, 98.25-102.12% for caffeine and 98.15-102.3% for phenobarbital) (RSD: 1.21-1.85%) were found to be satisfactory. The proposed HPLC method has been applied for the determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in Malophenum tablets. The obtained RSD values were within 0.99-1.21%. The developed method is rapid and sensitive and therefore suitable for routine control of these drugs in dosage form.
PB  - Elsevier Science Sa, Lausanne
T2  - Farmaco
T1  - HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets
VL  - 57
IS  - 9
SP  - 709
EP  - 713
DO  - 10.1016/S0014-827X(02)01265-X
ER  - 

@article{
author = "Franeta, JT and Agbaba, Danica and Erić, Slavica and Pavkov, S and Aleksić, Mirjana
 and Vladimirov, S",
year = "2002",
abstract = "This paper present a HPLC method for simultaneous determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets, using chromatographic system consisting a Bio Rad 18 01 solvent pump, Rheodine 71 25 injector and Bio Rad 18 01 UV-Vis Detector. Separation was achieved using Bio SiL HL C 18, 5 mum, 250 x 4.6 mm column. Mixture of acetonitrile-water (25:75 v/v) adjusted to pH 2.5 with phosphoric acid was used as a mobile phase at a flow rate of 2.0 ml(-1) min UV detection was at 207 nm range 0.01 AUFS. Under the same conditions it was possible to determine the level of salicylic acid. The chromatographic parameters such as retention times, capacity factor, peak asymmetry, selectivity factor and resolution factor was determined. The validation parameters: linearity (r > 0.998), intra-day precision (RSD: 0.36-1.89%) and inter-day precision (RSD: 0.58-2.18%), sensitivity (LOD: 9 x 10(-5)-1.7 x 10(-4) mg ml(-1) and LOQ: 2.5 x 10(-4)-5.6 x 10(-4) mg ml(-1)), accuracy (recoveries: 98.35-99.14%) and reproducibility (recovery values: 98.74-102.08% for acetylsalicylic acid, 99.93-102.11% for paracetamol, 98.25-102.12% for caffeine and 98.15-102.3% for phenobarbital) (RSD: 1.21-1.85%) were found to be satisfactory. The proposed HPLC method has been applied for the determination of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in Malophenum tablets. The obtained RSD values were within 0.99-1.21%. The developed method is rapid and sensitive and therefore suitable for routine control of these drugs in dosage form.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Farmaco",
title = "HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets",
volume = "57",
number = "9",
pages = "709-713",
doi = "10.1016/S0014-827X(02)01265-X"
}

Franeta, J., Agbaba, D., Erić, S., Pavkov, S., Aleksić, M.,& Vladimirov, S.. (2002). HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets. in Farmaco
Elsevier Science Sa, Lausanne., 57(9), 709-713.
https://doi.org/10.1016/S0014-827X(02)01265-X

Franeta J, Agbaba D, Erić S, Pavkov S, Aleksić M, Vladimirov S. HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets. in Farmaco. 2002;57(9):709-713.
doi:10.1016/S0014-827X(02)01265-X .

Franeta, JT, Agbaba, Danica, Erić, Slavica, Pavkov, S, Aleksić, Mirjana
, Vladimirov, S, "HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets" in Farmaco, 57, no. 9 (2002):709-713,
https://doi.org/10.1016/S0014-827X(02)01265-X . .

TY  - JOUR
AU  - Marinković, Valentina
AU  - Agbaba, Danica
AU  - Vladimirov, S
AU  - Stanković, S
PY  - 2001
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/294
AB  - A method has been developed for separation of nitrendipine and its impurities of reaction partners and side reaction products by high-performance liquid chromatographic method on a RP-ls column and detection at 238 nm. The mobile phase composition that provided an acceptable nitrendipine resolution, in large excess and possible impurities, in a short elution time, is methanol:water (70:30) and pH 3. Linearity (r greater than or equal to 0.999), reproducibility (RSD = 0.8-1.4%), determination limit (0.5 2%,) and recovery (99.8-102.3) were validated and found to be satisfactory. This method enables monitoring of the process of synthesis, as well as the choice of the synthetic design.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis
VL  - 24
IS  - 5-6
SP  - 993
EP  - 998
DO  - 10.1016/S0731-7085(00)00531-8
ER  - 

@article{
author = "Marinković, Valentina and Agbaba, Danica and Vladimirov, S and Stanković, S",
year = "2001",
abstract = "A method has been developed for separation of nitrendipine and its impurities of reaction partners and side reaction products by high-performance liquid chromatographic method on a RP-ls column and detection at 238 nm. The mobile phase composition that provided an acceptable nitrendipine resolution, in large excess and possible impurities, in a short elution time, is methanol:water (70:30) and pH 3. Linearity (r greater than or equal to 0.999), reproducibility (RSD = 0.8-1.4%), determination limit (0.5 2%,) and recovery (99.8-102.3) were validated and found to be satisfactory. This method enables monitoring of the process of synthesis, as well as the choice of the synthetic design.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis",
volume = "24",
number = "5-6",
pages = "993-998",
doi = "10.1016/S0731-7085(00)00531-8"
}

Marinković, V., Agbaba, D., Vladimirov, S.,& Stanković, S.. (2001). Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis. in Journal of Pharmaceutical and Biomedical Analysis
Pergamon-Elsevier Science Ltd, Oxford., 24(5-6), 993-998.
https://doi.org/10.1016/S0731-7085(00)00531-8

Marinković V, Agbaba D, Vladimirov S, Stanković S. Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis. in Journal of Pharmaceutical and Biomedical Analysis. 2001;24(5-6):993-998.
doi:10.1016/S0731-7085(00)00531-8 .

Marinković, Valentina, Agbaba, Danica, Vladimirov, S, Stanković, S, "Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis" in Journal of Pharmaceutical and Biomedical Analysis, 24, no. 5-6 (2001):993-998,
https://doi.org/10.1016/S0731-7085(00)00531-8 . .

TY  - JOUR
AU  - Čudina, Olivera
AU  - Brborić, Jasmina
AU  - Vujić, Zorica
AU  - Radulović, D
AU  - Vladimirov, S
PY  - 2000
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/247
AB  - Fluocortolone and its esters are synthetic corticosteroids used topically in the treatment of various skin disorders. A method that can be successfully used for the separation and determination of fluocortolone pivalate and fluocortolone hexanoate in suppositories was developed. This method is based on reverse-phase HPLC on Supelcosil LC-18 (25 cm x 4.6 mm, 5 mu m), using methanol-acetonitrile-water-glacial acetic acid (17: 46:37:0.4 v/v/v/v) as mobile phase at a flow rate of 3.0 ml/min. Detection was carried out using a UV detector at 238 nm. The method developed was validated, and calibration curves were established dependent on peak area. The validated ranges for fluocortolone pivalate and fluocortolone hexanoate are 15-305 mu g/ml (r = 0.9995) and 15-315 mu g/ml (r = 0.9996), respectively. The limits of detection and the limits of quantification for both esters were also determined.
PB  - Elsevier Science Sa, Lausanne
T2  - Farmaco
T1  - Determination of fluocortolone pivalate and fluocortolone hexanoate in suppositories using reverse-phase HPLC
VL  - 55
IS  - 2
SP  - 125
EP  - 127
DO  - 10.1016/S0014-827X(00)00003-3
ER  - 

@article{
author = "Čudina, Olivera and Brborić, Jasmina and Vujić, Zorica and Radulović, D and Vladimirov, S",
year = "2000",
abstract = "Fluocortolone and its esters are synthetic corticosteroids used topically in the treatment of various skin disorders. A method that can be successfully used for the separation and determination of fluocortolone pivalate and fluocortolone hexanoate in suppositories was developed. This method is based on reverse-phase HPLC on Supelcosil LC-18 (25 cm x 4.6 mm, 5 mu m), using methanol-acetonitrile-water-glacial acetic acid (17: 46:37:0.4 v/v/v/v) as mobile phase at a flow rate of 3.0 ml/min. Detection was carried out using a UV detector at 238 nm. The method developed was validated, and calibration curves were established dependent on peak area. The validated ranges for fluocortolone pivalate and fluocortolone hexanoate are 15-305 mu g/ml (r = 0.9995) and 15-315 mu g/ml (r = 0.9996), respectively. The limits of detection and the limits of quantification for both esters were also determined.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Farmaco",
title = "Determination of fluocortolone pivalate and fluocortolone hexanoate in suppositories using reverse-phase HPLC",
volume = "55",
number = "2",
pages = "125-127",
doi = "10.1016/S0014-827X(00)00003-3"
}

Čudina, O., Brborić, J., Vujić, Z., Radulović, D.,& Vladimirov, S.. (2000). Determination of fluocortolone pivalate and fluocortolone hexanoate in suppositories using reverse-phase HPLC. in Farmaco
Elsevier Science Sa, Lausanne., 55(2), 125-127.
https://doi.org/10.1016/S0014-827X(00)00003-3

Čudina O, Brborić J, Vujić Z, Radulović D, Vladimirov S. Determination of fluocortolone pivalate and fluocortolone hexanoate in suppositories using reverse-phase HPLC. in Farmaco. 2000;55(2):125-127.
doi:10.1016/S0014-827X(00)00003-3 .

Čudina, Olivera, Brborić, Jasmina, Vujić, Zorica, Radulović, D, Vladimirov, S, "Determination of fluocortolone pivalate and fluocortolone hexanoate in suppositories using reverse-phase HPLC" in Farmaco, 55, no. 2 (2000):125-127,
https://doi.org/10.1016/S0014-827X(00)00003-3 . .

TY  - JOUR
AU  - Jovanović, MS
AU  - Brborić, Jasmina
AU  - Vladimirov, S
AU  - Suturkova, L
PY  - 2000
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/236
AB  - The partition coefficient (log P) for n-octanol/water system was calculated applying PACO program for various theoretically possible mono and dihalogenated IDA derivatives. Some of the synthesized ligands (SOLCOIODIDA, IODIDA and DIIODIDA) were labeled with the technetium-99m. The biodistribution and influence of bilirubin on their biokinetics were investigated in rats. The correlation between partition coefficients of ligands increase (log P) and better hepatobiliary properties of Tc-99m-IDA derivatives was determined. The values of log P increase from 1.16 for SOLCOIODIDA, 3.11 for IODIDA to 3.47 for DIIODIDA. In correlation with these results, biliary excretion decreased for 59% for Tc-99m-SOLCOIODIDA and 11% for Tc-99m-IODIDA and Tc-99m-DIIODIDA under hyperbilirubinemia (3.5 min after injection) and 45%, 11% and 0.38% respectively (15 min after injection). The highest biliary excretion had Tc-99m-DIIODIDA (55.4% for 3.5 min). Considering the correlation between hepatobiliary properties and log P, the evaluation of biological properties for various trifluoromethyl mono and dihalogenated IDA derivatives was performed on the basis of the calculated log P in order to synthetize a new radiopharmaceutical for hepatobiliary scintigraphy.
PB  - Kluwer Academic Publ, Dordrecht
T2  - Journal of Radioanalytical and Nuclear Chemistry
T1  - Correlation between lipophilicity of the ligands and the hepatobiliary properties of the radiopharmaceuticals: Approach to the development of new IDA derivatives
VL  - 245
IS  - 3
SP  - 555
EP  - 560
DO  - 10.1023/A:1006709310527
ER  - 

@article{
author = "Jovanović, MS and Brborić, Jasmina and Vladimirov, S and Suturkova, L",
year = "2000",
abstract = "The partition coefficient (log P) for n-octanol/water system was calculated applying PACO program for various theoretically possible mono and dihalogenated IDA derivatives. Some of the synthesized ligands (SOLCOIODIDA, IODIDA and DIIODIDA) were labeled with the technetium-99m. The biodistribution and influence of bilirubin on their biokinetics were investigated in rats. The correlation between partition coefficients of ligands increase (log P) and better hepatobiliary properties of Tc-99m-IDA derivatives was determined. The values of log P increase from 1.16 for SOLCOIODIDA, 3.11 for IODIDA to 3.47 for DIIODIDA. In correlation with these results, biliary excretion decreased for 59% for Tc-99m-SOLCOIODIDA and 11% for Tc-99m-IODIDA and Tc-99m-DIIODIDA under hyperbilirubinemia (3.5 min after injection) and 45%, 11% and 0.38% respectively (15 min after injection). The highest biliary excretion had Tc-99m-DIIODIDA (55.4% for 3.5 min). Considering the correlation between hepatobiliary properties and log P, the evaluation of biological properties for various trifluoromethyl mono and dihalogenated IDA derivatives was performed on the basis of the calculated log P in order to synthetize a new radiopharmaceutical for hepatobiliary scintigraphy.",
publisher = "Kluwer Academic Publ, Dordrecht",
journal = "Journal of Radioanalytical and Nuclear Chemistry",
title = "Correlation between lipophilicity of the ligands and the hepatobiliary properties of the radiopharmaceuticals: Approach to the development of new IDA derivatives",
volume = "245",
number = "3",
pages = "555-560",
doi = "10.1023/A:1006709310527"
}

Jovanović, M., Brborić, J., Vladimirov, S.,& Suturkova, L.. (2000). Correlation between lipophilicity of the ligands and the hepatobiliary properties of the radiopharmaceuticals: Approach to the development of new IDA derivatives. in Journal of Radioanalytical and Nuclear Chemistry
Kluwer Academic Publ, Dordrecht., 245(3), 555-560.
https://doi.org/10.1023/A:1006709310527

Jovanović M, Brborić J, Vladimirov S, Suturkova L. Correlation between lipophilicity of the ligands and the hepatobiliary properties of the radiopharmaceuticals: Approach to the development of new IDA derivatives. in Journal of Radioanalytical and Nuclear Chemistry. 2000;245(3):555-560.
doi:10.1023/A:1006709310527 .

Jovanović, MS, Brborić, Jasmina, Vladimirov, S, Suturkova, L, "Correlation between lipophilicity of the ligands and the hepatobiliary properties of the radiopharmaceuticals: Approach to the development of new IDA derivatives" in Journal of Radioanalytical and Nuclear Chemistry, 245, no. 3 (2000):555-560,
https://doi.org/10.1023/A:1006709310527 . .

TY  - JOUR
AU  - Erić, Slavica
AU  - Agbaba, Danica
AU  - Vladimirov, S
AU  - Živanov-Stakić, Dobrila
PY  - 2000
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/237
AB  - The chromatographic behavior of cephalexine, cefaclore, ceftriaxone, cefiuime, and cefotaxime has been investigated on silica gel layers with binary mobile phases containing different amounts of organic modifier. The influence of type, chemical character, and position of substitution of functional groups (steric and structural effects) on the retention of analyzed compounds was of particular interest. Systematic investigation of the cephalosporins furnished much information about their hydrophobicity (R-M(0)), the mechanism of adsorption, and the possibilities of separation. Correlation of the hydrophobicity parameters R-M(0), m, and C-0 with the lipophilicity parameter log P was established by use of linear equations. The parameter C-0 was considered as directly applicable in quantitative structure-activity relationships of the cephalosporins.
PB  - Springer Hungarica Kiado Kft, Budapest
T2  - Journal of Planar Chromatography - Modern TLC
T1  - The retention behavior of several semisynthetic cephalosporins in planar chromatography
VL  - 13
IS  - 2
SP  - 88
EP  - 92
UR  - https://hdl.handle.net/21.15107/rcub_farfar_237
ER  - 

@article{
author = "Erić, Slavica and Agbaba, Danica and Vladimirov, S and Živanov-Stakić, Dobrila",
year = "2000",
abstract = "The chromatographic behavior of cephalexine, cefaclore, ceftriaxone, cefiuime, and cefotaxime has been investigated on silica gel layers with binary mobile phases containing different amounts of organic modifier. The influence of type, chemical character, and position of substitution of functional groups (steric and structural effects) on the retention of analyzed compounds was of particular interest. Systematic investigation of the cephalosporins furnished much information about their hydrophobicity (R-M(0)), the mechanism of adsorption, and the possibilities of separation. Correlation of the hydrophobicity parameters R-M(0), m, and C-0 with the lipophilicity parameter log P was established by use of linear equations. The parameter C-0 was considered as directly applicable in quantitative structure-activity relationships of the cephalosporins.",
publisher = "Springer Hungarica Kiado Kft, Budapest",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "The retention behavior of several semisynthetic cephalosporins in planar chromatography",
volume = "13",
number = "2",
pages = "88-92",
url = "https://hdl.handle.net/21.15107/rcub_farfar_237"
}

Erić, S., Agbaba, D., Vladimirov, S.,& Živanov-Stakić, D.. (2000). The retention behavior of several semisynthetic cephalosporins in planar chromatography. in Journal of Planar Chromatography - Modern TLC
Springer Hungarica Kiado Kft, Budapest., 13(2), 88-92.
https://hdl.handle.net/21.15107/rcub_farfar_237

Erić S, Agbaba D, Vladimirov S, Živanov-Stakić D. The retention behavior of several semisynthetic cephalosporins in planar chromatography. in Journal of Planar Chromatography - Modern TLC. 2000;13(2):88-92.
https://hdl.handle.net/21.15107/rcub_farfar_237 .

Erić, Slavica, Agbaba, Danica, Vladimirov, S, Živanov-Stakić, Dobrila, "The retention behavior of several semisynthetic cephalosporins in planar chromatography" in Journal of Planar Chromatography - Modern TLC, 13, no. 2 (2000):88-92,
https://hdl.handle.net/21.15107/rcub_farfar_237 .

TY  - JOUR
AU  - Jovanović, MS
AU  - Brborić, Jasmina
AU  - Vladimirov, S
AU  - Zmbova, B
AU  - Vuksanović, LJ
AU  - Živanov-Stakić, Dobrila
AU  - Obradović, V
PY  - 1999
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/219
AB  - A new diiodine substituted LDA derivative, 2,4-diiodine-6-methyl IDA (DIIODIDA) was synthesized and labeled with Tc-99m. It was established that Tc-99m-DIIODIDA had high radiochemical purity. Biodistribution and influence of bilirubin on Tc-99m-DIIODIDA biokinetics has been studied in rats and compared to the corresponding results for Tc-99m-SOLCOIODIDA. Related to Tc-99m-SOLCOIODIDA, Tc-99m-DIIODIDA has much better biliary exretion (55.18 versus 43.63%). No change of Tc-99m-DIIODIDA biokinetics, under influence of bilirubin was noticed. Biliary excretion of Tc-99m-SOLCOIODIDA has been reduced for about 60%. The protein binding of Tc-99m-DIIODIDA and Tc-99m-SOLCOIODIDA were also determined, using in vitro method of precipitation. These results showed that Tc-99m-DIIODIDA hepatobiliary imaging agent is superior to the presently used Tc-99m-monoiodine IDA derivatives.
PB  - Springer
PB  - Elsevier Science B. V., Amsterdam
T2  - Journal of Radioanalytical and Nuclear Chemistry
T1  - New Tc-99m-diiodine substituted IDA derivative (DIIODIDA) for hepatobiliary imaging
VL  - 240
IS  - 1
SP  - 321
EP  - 324
DO  - 10.1007/BF02349171
ER  - 

@article{
author = "Jovanović, MS and Brborić, Jasmina and Vladimirov, S and Zmbova, B and Vuksanović, LJ and Živanov-Stakić, Dobrila and Obradović, V",
year = "1999",
abstract = "A new diiodine substituted LDA derivative, 2,4-diiodine-6-methyl IDA (DIIODIDA) was synthesized and labeled with Tc-99m. It was established that Tc-99m-DIIODIDA had high radiochemical purity. Biodistribution and influence of bilirubin on Tc-99m-DIIODIDA biokinetics has been studied in rats and compared to the corresponding results for Tc-99m-SOLCOIODIDA. Related to Tc-99m-SOLCOIODIDA, Tc-99m-DIIODIDA has much better biliary exretion (55.18 versus 43.63%). No change of Tc-99m-DIIODIDA biokinetics, under influence of bilirubin was noticed. Biliary excretion of Tc-99m-SOLCOIODIDA has been reduced for about 60%. The protein binding of Tc-99m-DIIODIDA and Tc-99m-SOLCOIODIDA were also determined, using in vitro method of precipitation. These results showed that Tc-99m-DIIODIDA hepatobiliary imaging agent is superior to the presently used Tc-99m-monoiodine IDA derivatives.",
publisher = "Springer, Elsevier Science B. V., Amsterdam",
journal = "Journal of Radioanalytical and Nuclear Chemistry",
title = "New Tc-99m-diiodine substituted IDA derivative (DIIODIDA) for hepatobiliary imaging",
volume = "240",
number = "1",
pages = "321-324",
doi = "10.1007/BF02349171"
}

Jovanović, M., Brborić, J., Vladimirov, S., Zmbova, B., Vuksanović, L., Živanov-Stakić, D.,& Obradović, V.. (1999). New Tc-99m-diiodine substituted IDA derivative (DIIODIDA) for hepatobiliary imaging. in Journal of Radioanalytical and Nuclear Chemistry
Springer., 240(1), 321-324.
https://doi.org/10.1007/BF02349171

Jovanović M, Brborić J, Vladimirov S, Zmbova B, Vuksanović L, Živanov-Stakić D, Obradović V. New Tc-99m-diiodine substituted IDA derivative (DIIODIDA) for hepatobiliary imaging. in Journal of Radioanalytical and Nuclear Chemistry. 1999;240(1):321-324.
doi:10.1007/BF02349171 .

Jovanović, MS, Brborić, Jasmina, Vladimirov, S, Zmbova, B, Vuksanović, LJ, Živanov-Stakić, Dobrila, Obradović, V, "New Tc-99m-diiodine substituted IDA derivative (DIIODIDA) for hepatobiliary imaging" in Journal of Radioanalytical and Nuclear Chemistry, 240, no. 1 (1999):321-324,
https://doi.org/10.1007/BF02349171 . .

TY  - JOUR
AU  - Agbaba, Danica
AU  - Miljković, Tatjana
AU  - Marinković, Valentina
AU  - Živanov-Stakić, Dobrila
AU  - Vladimirov, Sote
PY  - 1999
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/214
AB  - A simple and reliable thin-layer chromatographic method for determining sulpiride and impurities of 2-aminomethyl-1-ethylpyrrolidine and methyl-5-sulphamoyl-2-methoxybenzoate was developed and validated. A methylene chloride-methanol-ammonia solution (25%; 18 + 2.8 + 0.4, v/v) solvent system is used for separation and quantitative evaluation of chromatograms. The chromatographic plate is first scanned at 240 nm to locate chromatographic zones corresponding to sulpiride and methyl-5-sulphamoyl-2-methoxybenzoate. Then 2-aminomethyl-1-ethylpyrrolidine is derivatized in situ with ninhydrin, and resulting colored spots are measured at 500 nm. The method is reproducible and convenient for quantitative analysis and purity control of sulpiride in its raw material and in its dosage forms.
PB  - AOAC International, Gaithersburg
T2  - Journal of AOAC International
T1  - Quantitative analysis of sulpiride and impurities of 2-aminomethyl-1-ethylpyrrolidine and methyl-5-sulphamoyl-2-methoxybenzoate in pharmaceuticals by high-performance thin-layer chromatography and scanning densitometry
VL  - 82
IS  - 4
SP  - 825
EP  - 829
DO  - 10.1093/jaoac/82.4.825
ER  - 

@article{
author = "Agbaba, Danica and Miljković, Tatjana and Marinković, Valentina and Živanov-Stakić, Dobrila and Vladimirov, Sote",
year = "1999",
abstract = "A simple and reliable thin-layer chromatographic method for determining sulpiride and impurities of 2-aminomethyl-1-ethylpyrrolidine and methyl-5-sulphamoyl-2-methoxybenzoate was developed and validated. A methylene chloride-methanol-ammonia solution (25%; 18 + 2.8 + 0.4, v/v) solvent system is used for separation and quantitative evaluation of chromatograms. The chromatographic plate is first scanned at 240 nm to locate chromatographic zones corresponding to sulpiride and methyl-5-sulphamoyl-2-methoxybenzoate. Then 2-aminomethyl-1-ethylpyrrolidine is derivatized in situ with ninhydrin, and resulting colored spots are measured at 500 nm. The method is reproducible and convenient for quantitative analysis and purity control of sulpiride in its raw material and in its dosage forms.",
publisher = "AOAC International, Gaithersburg",
journal = "Journal of AOAC International",
title = "Quantitative analysis of sulpiride and impurities of 2-aminomethyl-1-ethylpyrrolidine and methyl-5-sulphamoyl-2-methoxybenzoate in pharmaceuticals by high-performance thin-layer chromatography and scanning densitometry",
volume = "82",
number = "4",
pages = "825-829",
doi = "10.1093/jaoac/82.4.825"
}

Agbaba, D., Miljković, T., Marinković, V., Živanov-Stakić, D.,& Vladimirov, S.. (1999). Quantitative analysis of sulpiride and impurities of 2-aminomethyl-1-ethylpyrrolidine and methyl-5-sulphamoyl-2-methoxybenzoate in pharmaceuticals by high-performance thin-layer chromatography and scanning densitometry. in Journal of AOAC International
AOAC International, Gaithersburg., 82(4), 825-829.
https://doi.org/10.1093/jaoac/82.4.825

Agbaba D, Miljković T, Marinković V, Živanov-Stakić D, Vladimirov S. Quantitative analysis of sulpiride and impurities of 2-aminomethyl-1-ethylpyrrolidine and methyl-5-sulphamoyl-2-methoxybenzoate in pharmaceuticals by high-performance thin-layer chromatography and scanning densitometry. in Journal of AOAC International. 1999;82(4):825-829.
doi:10.1093/jaoac/82.4.825 .

Agbaba, Danica, Miljković, Tatjana, Marinković, Valentina, Živanov-Stakić, Dobrila, Vladimirov, Sote, "Quantitative analysis of sulpiride and impurities of 2-aminomethyl-1-ethylpyrrolidine and methyl-5-sulphamoyl-2-methoxybenzoate in pharmaceuticals by high-performance thin-layer chromatography and scanning densitometry" in Journal of AOAC International, 82, no. 4 (1999):825-829,
https://doi.org/10.1093/jaoac/82.4.825 . .

TY  - JOUR
AU  - Marković, G
AU  - Agbaba, Danica
AU  - Stakić, D.Ž
AU  - Vladimirov, S
PY  - 1999
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/215
AB  - A simple and reliable thin-layer chromatographic method for the determination of N,N-diethyl-m-toluamide (DEET) and dimethyl phthalate (DMP) in raw material and cosmetic products was developed and validated. A benzene-diethyl ether-cyclohexane (5:3:2, v/v/v) solvent system was used for quantitative evaluation of chromatograms. The chromatographic zones corresponding to the spots of DEET and DMP on the silica gel plates were scanned in the reflectance/absorbance mode at 230 nm. The method was found to be reproducible and convenient for the quantitative analysis of DEET and DMF in raw material and cosmetic products.
PB  - Elsevier Science BV, Amsterdam
T2  - Journal of Chromatography A
T1  - Determination of some insect repellents in cosmetic products by high-performance thin-layer chromatography
VL  - 847
IS  - 1-2
SP  - 365
EP  - 368
DO  - 10.1016/S0021-9673(99)00029-1
ER  - 

@article{
author = "Marković, G and Agbaba, Danica and Stakić, D.Ž and Vladimirov, S",
year = "1999",
abstract = "A simple and reliable thin-layer chromatographic method for the determination of N,N-diethyl-m-toluamide (DEET) and dimethyl phthalate (DMP) in raw material and cosmetic products was developed and validated. A benzene-diethyl ether-cyclohexane (5:3:2, v/v/v) solvent system was used for quantitative evaluation of chromatograms. The chromatographic zones corresponding to the spots of DEET and DMP on the silica gel plates were scanned in the reflectance/absorbance mode at 230 nm. The method was found to be reproducible and convenient for the quantitative analysis of DEET and DMF in raw material and cosmetic products.",
publisher = "Elsevier Science BV, Amsterdam",
journal = "Journal of Chromatography A",
title = "Determination of some insect repellents in cosmetic products by high-performance thin-layer chromatography",
volume = "847",
number = "1-2",
pages = "365-368",
doi = "10.1016/S0021-9673(99)00029-1"
}

Marković, G., Agbaba, D., Stakić, D.Ž,& Vladimirov, S.. (1999). Determination of some insect repellents in cosmetic products by high-performance thin-layer chromatography. in Journal of Chromatography A
Elsevier Science BV, Amsterdam., 847(1-2), 365-368.
https://doi.org/10.1016/S0021-9673(99)00029-1

Marković G, Agbaba D, Stakić D, Vladimirov S. Determination of some insect repellents in cosmetic products by high-performance thin-layer chromatography. in Journal of Chromatography A. 1999;847(1-2):365-368.
doi:10.1016/S0021-9673(99)00029-1 .

Marković, G, Agbaba, Danica, Stakić, D.Ž, Vladimirov, S, "Determination of some insect repellents in cosmetic products by high-performance thin-layer chromatography" in Journal of Chromatography A, 847, no. 1-2 (1999):365-368,
https://doi.org/10.1016/S0021-9673(99)00029-1 . .

TY  - JOUR
AU  - Vladimirov, S
AU  - Ivanisević, L
AU  - Agbaba, Danica
AU  - Brborić, Jasmina
AU  - Živanov-Stakić, Dobrila
PY  - 1998
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/184
AB  - A simple HPLC procedure, suitable for the determination of sodium fusidate (SF) in dosage forms, was developed. The method involves using a UV detector (208 nm) in the presence of basic buffered media (pH 7.25) under reversed-phase conditions (Supelcosil(R) LC18(TM), 3 mu m particles). The linear regression between the concentration of SF and the peak area, y = -4.4566 + 8.9238x with a coefficient of correlation r = 0.9985, was confirmed for SF in the concentration range from 25 mu g/ml to 150 mu g/ml. The detection limit of SF was 12.5 mu g/ml. The HPLC method was applied for the determination of SF in dosage forms: Stanicid(R) coated tablets, Stanicid(R) ointment and Stanicid(R) sterile gauze dressing. The concentrations and statistical parameters of sodium fusidate for all the investigated dosage forms were satisfactory and ranged from 100.41 to 105.39% (the R. S. D. ranged from 1.51 to 2.75%).
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Determination of sodium fusidate in dosage forms by high performance liquid chromatography
VL  - 63
IS  - 6
SP  - 475
EP  - 480
UR  - https://hdl.handle.net/21.15107/rcub_farfar_184
ER  - 

@article{
author = "Vladimirov, S and Ivanisević, L and Agbaba, Danica and Brborić, Jasmina and Živanov-Stakić, Dobrila",
year = "1998",
abstract = "A simple HPLC procedure, suitable for the determination of sodium fusidate (SF) in dosage forms, was developed. The method involves using a UV detector (208 nm) in the presence of basic buffered media (pH 7.25) under reversed-phase conditions (Supelcosil(R) LC18(TM), 3 mu m particles). The linear regression between the concentration of SF and the peak area, y = -4.4566 + 8.9238x with a coefficient of correlation r = 0.9985, was confirmed for SF in the concentration range from 25 mu g/ml to 150 mu g/ml. The detection limit of SF was 12.5 mu g/ml. The HPLC method was applied for the determination of SF in dosage forms: Stanicid(R) coated tablets, Stanicid(R) ointment and Stanicid(R) sterile gauze dressing. The concentrations and statistical parameters of sodium fusidate for all the investigated dosage forms were satisfactory and ranged from 100.41 to 105.39% (the R. S. D. ranged from 1.51 to 2.75%).",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Determination of sodium fusidate in dosage forms by high performance liquid chromatography",
volume = "63",
number = "6",
pages = "475-480",
url = "https://hdl.handle.net/21.15107/rcub_farfar_184"
}

Vladimirov, S., Ivanisević, L., Agbaba, D., Brborić, J.,& Živanov-Stakić, D.. (1998). Determination of sodium fusidate in dosage forms by high performance liquid chromatography. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 63(6), 475-480.
https://hdl.handle.net/21.15107/rcub_farfar_184

Vladimirov S, Ivanisević L, Agbaba D, Brborić J, Živanov-Stakić D. Determination of sodium fusidate in dosage forms by high performance liquid chromatography. in Journal of the Serbian Chemical Society. 1998;63(6):475-480.
https://hdl.handle.net/21.15107/rcub_farfar_184 .

Vladimirov, S, Ivanisević, L, Agbaba, Danica, Brborić, Jasmina, Živanov-Stakić, Dobrila, "Determination of sodium fusidate in dosage forms by high performance liquid chromatography" in Journal of the Serbian Chemical Society, 63, no. 6 (1998):475-480,
https://hdl.handle.net/21.15107/rcub_farfar_184 .

TY  - CONF
AU  - Agbaba, Danica
AU  - Erić, Slavica
AU  - Živanov-Stakić, Dobrila
AU  - Vladimirov, Sote
PY  - 1998
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/206
AB  - A simple and reliable HPTLC method for the simultaneous determination of cephalexin and cefaclor is developed and validated. The methanol-ethyl acetate-acetone-water (5:2.5:2.5:1.5 v/v/v/v) solvent system is used for the quantitative evaluation of chromatograms. The chromatographic zones, corresponding to the spots of cephalexin and cefaclor on the silica gel plates, are scanned in the reflectance/absorbance mode at 265 nm. The method is found to be reproducible and convenient for the quantitative analysis of cephalexin and cefaclor in its dosage forms.
PB  - John Wiley and Sons Ltd
C3  - Biomedical Chromatography
T1  - HPTLC assay of cephalexin and cefaclor in pharmaceuticals
VL  - 12
IS  - 3
SP  - 133
EP  - 135
DO  - 10.1002/(SICI)1099-0801(199805/06)12:3<133::AID-BMC780>3.0.CO;2-8
ER  - 

@conference{
author = "Agbaba, Danica and Erić, Slavica and Živanov-Stakić, Dobrila and Vladimirov, Sote",
year = "1998",
abstract = "A simple and reliable HPTLC method for the simultaneous determination of cephalexin and cefaclor is developed and validated. The methanol-ethyl acetate-acetone-water (5:2.5:2.5:1.5 v/v/v/v) solvent system is used for the quantitative evaluation of chromatograms. The chromatographic zones, corresponding to the spots of cephalexin and cefaclor on the silica gel plates, are scanned in the reflectance/absorbance mode at 265 nm. The method is found to be reproducible and convenient for the quantitative analysis of cephalexin and cefaclor in its dosage forms.",
publisher = "John Wiley and Sons Ltd",
journal = "Biomedical Chromatography",
title = "HPTLC assay of cephalexin and cefaclor in pharmaceuticals",
volume = "12",
number = "3",
pages = "133-135",
doi = "10.1002/(SICI)1099-0801(199805/06)12:3<133::AID-BMC780>3.0.CO;2-8"
}

Agbaba, D., Erić, S., Živanov-Stakić, D.,& Vladimirov, S.. (1998). HPTLC assay of cephalexin and cefaclor in pharmaceuticals. in Biomedical Chromatography
John Wiley and Sons Ltd., 12(3), 133-135.
https://doi.org/10.1002/(SICI)1099-0801(199805/06)12:3<133::AID-BMC780>3.0.CO;2-8

Agbaba D, Erić S, Živanov-Stakić D, Vladimirov S. HPTLC assay of cephalexin and cefaclor in pharmaceuticals. in Biomedical Chromatography. 1998;12(3):133-135.
doi:10.1002/(SICI)1099-0801(199805/06)12:3<133::AID-BMC780>3.0.CO;2-8 .

Agbaba, Danica, Erić, Slavica, Živanov-Stakić, Dobrila, Vladimirov, Sote, "HPTLC assay of cephalexin and cefaclor in pharmaceuticals" in Biomedical Chromatography, 12, no. 3 (1998):133-135,
https://doi.org/10.1002/(SICI)1099-0801(199805/06)12:3<133::AID-BMC780>3.0.CO;2-8 . .

TY  - JOUR
AU  - Erić-Jovanović, S
AU  - Agbaba, Danica
AU  - Živanov-Stakić, Dobrila
AU  - Vladimirov, S
PY  - 1998
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/197
AB  - The objective of this investigation was to develop a HPTLC method for the determination of ceftriaxone, cefixime and cefotaxime, cephalosporins widely used in clinical practice, High performance TLC of cephalosporins was performed on pre-coated silica gel HPTLC plates with concentrating zone (2.5 x 10 cm) by development in mobile phase ethyl acetate-acetone-methanol-water (5:2.5:2.5:1.5 v/v/v/v). A TLC scanner set at 270 nm was used for direct evaluation of the chromatograms in reflectance/absorbance mode. The calibration curves were established as dependence of peak height (linear and polynomial regression) and peak area (polynomial regression) versus ng level (125-500 ng for all cephalosporins investigated). Relative standard deviations obtained from calibration curves was compared. Precision (RSD: 1.12-2.91% (peak height versus ng) and RSD: 1.05-2.75% (peak area versus ng)), and detection limits (ng level) was validated and found to be satisfactory. The method was found to be reproducible and convenient for quantitative analysis of ceftriaxone, cefixime and cefotaxime in their raw materials and their dosage forms.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Journal of Pharmaceutical and Biomedical Analysis
T1  - HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms
VL  - 18
IS  - 4-5
SP  - 893
EP  - 898
DO  - 10.1016/S0731-7085(98)00274-X
ER  - 

@article{
author = "Erić-Jovanović, S and Agbaba, Danica and Živanov-Stakić, Dobrila and Vladimirov, S",
year = "1998",
abstract = "The objective of this investigation was to develop a HPTLC method for the determination of ceftriaxone, cefixime and cefotaxime, cephalosporins widely used in clinical practice, High performance TLC of cephalosporins was performed on pre-coated silica gel HPTLC plates with concentrating zone (2.5 x 10 cm) by development in mobile phase ethyl acetate-acetone-methanol-water (5:2.5:2.5:1.5 v/v/v/v). A TLC scanner set at 270 nm was used for direct evaluation of the chromatograms in reflectance/absorbance mode. The calibration curves were established as dependence of peak height (linear and polynomial regression) and peak area (polynomial regression) versus ng level (125-500 ng for all cephalosporins investigated). Relative standard deviations obtained from calibration curves was compared. Precision (RSD: 1.12-2.91% (peak height versus ng) and RSD: 1.05-2.75% (peak area versus ng)), and detection limits (ng level) was validated and found to be satisfactory. The method was found to be reproducible and convenient for quantitative analysis of ceftriaxone, cefixime and cefotaxime in their raw materials and their dosage forms.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Journal of Pharmaceutical and Biomedical Analysis",
title = "HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms",
volume = "18",
number = "4-5",
pages = "893-898",
doi = "10.1016/S0731-7085(98)00274-X"
}

Erić-Jovanović, S., Agbaba, D., Živanov-Stakić, D.,& Vladimirov, S.. (1998). HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms. in Journal of Pharmaceutical and Biomedical Analysis
Pergamon-Elsevier Science Ltd, Oxford., 18(4-5), 893-898.
https://doi.org/10.1016/S0731-7085(98)00274-X

Erić-Jovanović S, Agbaba D, Živanov-Stakić D, Vladimirov S. HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms. in Journal of Pharmaceutical and Biomedical Analysis. 1998;18(4-5):893-898.
doi:10.1016/S0731-7085(98)00274-X .

Erić-Jovanović, S, Agbaba, Danica, Živanov-Stakić, Dobrila, Vladimirov, S, "HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms" in Journal of Pharmaceutical and Biomedical Analysis, 18, no. 4-5 (1998):893-898,
https://doi.org/10.1016/S0731-7085(98)00274-X . .

TY  - JOUR
AU  - Agbaba, Danica
AU  - Erić-Jovanović, S
AU  - Živanov-Stakić, Dobrila
AU  - Vladimirov, S
PY  - 1998
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/202
AB  - The objective of this investigation was to develop an HPTLC method for the determination of ceftriaxone, cefixime and cefotaxime, cephalosporins widely used in clinical practice. High performance thin-layer chromatography of cephalosporins was performed on pre-coated silica gel HPTLC plates with concentration zones (2.5×10cm), development with mobile phase ethylacetate-acetone-methanol-water (5:2.5:2.5:1.5 v/v). A TLC scanner (Camag, Muttenz, Switzerland) set at 270 nm was used for direct evaluation of the chromatograms in reflectance/absorbance mode. The calibration curves were established dependant of peak height (linear and polinomial regression) and peak area (polinomial regression) vs ng level (125-500 ng for all cephalosporins investigated). Coefficients of variation obtained from calibration curves were compared. Precision (c.v.: 1.12-2.91% (peak height vs ng) and c.v.: 1.05-2.75% (peak area vs ng)), and detection limits (ng level) were found to be satisfactory. The method is reproducible and convenient for quantitative analysis of ceftriaxone, cefixime and cefotaxime raw materials and their different dosage forms.
PB  - APB Algemene Pharmaceutische Bond
T2  - Journal de Pharmacie de Belgique
T1  - HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms
VL  - 53
IS  - 3
SP  - 150
UR  - https://hdl.handle.net/21.15107/rcub_farfar_202
ER  - 

@article{
author = "Agbaba, Danica and Erić-Jovanović, S and Živanov-Stakić, Dobrila and Vladimirov, S",
year = "1998",
abstract = "The objective of this investigation was to develop an HPTLC method for the determination of ceftriaxone, cefixime and cefotaxime, cephalosporins widely used in clinical practice. High performance thin-layer chromatography of cephalosporins was performed on pre-coated silica gel HPTLC plates with concentration zones (2.5×10cm), development with mobile phase ethylacetate-acetone-methanol-water (5:2.5:2.5:1.5 v/v). A TLC scanner (Camag, Muttenz, Switzerland) set at 270 nm was used for direct evaluation of the chromatograms in reflectance/absorbance mode. The calibration curves were established dependant of peak height (linear and polinomial regression) and peak area (polinomial regression) vs ng level (125-500 ng for all cephalosporins investigated). Coefficients of variation obtained from calibration curves were compared. Precision (c.v.: 1.12-2.91% (peak height vs ng) and c.v.: 1.05-2.75% (peak area vs ng)), and detection limits (ng level) were found to be satisfactory. The method is reproducible and convenient for quantitative analysis of ceftriaxone, cefixime and cefotaxime raw materials and their different dosage forms.",
publisher = "APB Algemene Pharmaceutische Bond",
journal = "Journal de Pharmacie de Belgique",
title = "HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms",
volume = "53",
number = "3",
pages = "150",
url = "https://hdl.handle.net/21.15107/rcub_farfar_202"
}

Agbaba, D., Erić-Jovanović, S., Živanov-Stakić, D.,& Vladimirov, S.. (1998). HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms. in Journal de Pharmacie de Belgique
APB Algemene Pharmaceutische Bond., 53(3), 150.
https://hdl.handle.net/21.15107/rcub_farfar_202

Agbaba D, Erić-Jovanović S, Živanov-Stakić D, Vladimirov S. HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms. in Journal de Pharmacie de Belgique. 1998;53(3):150.
https://hdl.handle.net/21.15107/rcub_farfar_202 .

Agbaba, Danica, Erić-Jovanović, S, Živanov-Stakić, Dobrila, Vladimirov, S, "HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms" in Journal de Pharmacie de Belgique, 53, no. 3 (1998):150,
https://hdl.handle.net/21.15107/rcub_farfar_202 .

TY  - JOUR
AU  - Vladimirov, S
AU  - Marković, L
AU  - Agbaba, Danica
AU  - Živanov-Stakić, Dobrila
AU  - Brborić, Jasmina
PY  - 1997
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/166
AB  - A specific and simple HPLC procedure was developed, su table for the determination of dindamycin hydrochloride monohydrate (CLHC) and clindamycin 2-dihydrogenphosphate (CLPH) in pharmaceutical formulations. Rp-HPLC analysis was performed with a LCD-Analytical Consta Metric 3000 system, equipped with a Spectro Monitor 3100 UV/VIS detector. Lincosamides assay procedures were carried out on a Supelcosil R LC-18-DB (250 × 4,6 mm, 5 μm particles) column in an acetonitrile-potassium dihydrogenphosphate buffer (0.1 M; pH 2.50) (225:775 v/v) as mobile phase. Column effluents were monitored at 206 nm for clindamycin. The calibration curves in concentration ranges from 200 to 1800 μg/ml were established for the investigated clindamycins. The HPLC method was applied for the determination of clindamycin in pharmaceutical formulations. The obtained results and statistical parameters for both the investigated clindamycins in pharmaceutical formulations, were satisfactory and ranged from 99.99% to 104.18% (R.S.D. was ranged from 0.79% to 0.99%).
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - High performance liquid chromatographic determination of clindamycin in pharmaceutical formulations
VL  - 62
IS  - 2
SP  - 177
EP  - 181
UR  - https://hdl.handle.net/21.15107/rcub_farfar_166
ER  - 

@article{
author = "Vladimirov, S and Marković, L and Agbaba, Danica and Živanov-Stakić, Dobrila and Brborić, Jasmina",
year = "1997",
abstract = "A specific and simple HPLC procedure was developed, su table for the determination of dindamycin hydrochloride monohydrate (CLHC) and clindamycin 2-dihydrogenphosphate (CLPH) in pharmaceutical formulations. Rp-HPLC analysis was performed with a LCD-Analytical Consta Metric 3000 system, equipped with a Spectro Monitor 3100 UV/VIS detector. Lincosamides assay procedures were carried out on a Supelcosil R LC-18-DB (250 × 4,6 mm, 5 μm particles) column in an acetonitrile-potassium dihydrogenphosphate buffer (0.1 M; pH 2.50) (225:775 v/v) as mobile phase. Column effluents were monitored at 206 nm for clindamycin. The calibration curves in concentration ranges from 200 to 1800 μg/ml were established for the investigated clindamycins. The HPLC method was applied for the determination of clindamycin in pharmaceutical formulations. The obtained results and statistical parameters for both the investigated clindamycins in pharmaceutical formulations, were satisfactory and ranged from 99.99% to 104.18% (R.S.D. was ranged from 0.79% to 0.99%).",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "High performance liquid chromatographic determination of clindamycin in pharmaceutical formulations",
volume = "62",
number = "2",
pages = "177-181",
url = "https://hdl.handle.net/21.15107/rcub_farfar_166"
}

Vladimirov, S., Marković, L., Agbaba, D., Živanov-Stakić, D.,& Brborić, J.. (1997). High performance liquid chromatographic determination of clindamycin in pharmaceutical formulations. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 62(2), 177-181.
https://hdl.handle.net/21.15107/rcub_farfar_166

Vladimirov S, Marković L, Agbaba D, Živanov-Stakić D, Brborić J. High performance liquid chromatographic determination of clindamycin in pharmaceutical formulations. in Journal of the Serbian Chemical Society. 1997;62(2):177-181.
https://hdl.handle.net/21.15107/rcub_farfar_166 .

Vladimirov, S, Marković, L, Agbaba, Danica, Živanov-Stakić, Dobrila, Brborić, Jasmina, "High performance liquid chromatographic determination of clindamycin in pharmaceutical formulations" in Journal of the Serbian Chemical Society, 62, no. 2 (1997):177-181,
https://hdl.handle.net/21.15107/rcub_farfar_166 .

TY  - JOUR
AU  - Agbaba, Danica
AU  - Erić, Slavica
AU  - Karljiković-Rajić, Katarina
AU  - Vladimirov, S
AU  - Živanov-Stakić, Dobrila
PY  - 1997
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/169
AB  - Cephalexin, cefixime, ceftriaxone and cefotaxime were determined spectrophotometrically in the pure form and in pharmaceutical formulations by using ferrihydroxamate method. Reaction optimization with respect to reaction time and temperature has been investigated. Influence of the presence of ester functional group on the determination of cephalosporins as beta-lactams under conditions optimized was evaluated. Using cefotaxime sodiume as model drug with ester functional group, it was shown that proposed method gives equally acurate and precise results even ill the presence of ester functional group.
PB  - Marcel Dekker Inc, New York
T2  - Stem Cells Translational Medicine
T1  - Spectrophotometric determination of certain cephalosporins using ferrihydroxamate method
VL  - 30
IS  - 2
SP  - 309
EP  - 319
DO  - 10.1080/00387019708006990
ER  - 

@article{
author = "Agbaba, Danica and Erić, Slavica and Karljiković-Rajić, Katarina and Vladimirov, S and Živanov-Stakić, Dobrila",
year = "1997",
abstract = "Cephalexin, cefixime, ceftriaxone and cefotaxime were determined spectrophotometrically in the pure form and in pharmaceutical formulations by using ferrihydroxamate method. Reaction optimization with respect to reaction time and temperature has been investigated. Influence of the presence of ester functional group on the determination of cephalosporins as beta-lactams under conditions optimized was evaluated. Using cefotaxime sodiume as model drug with ester functional group, it was shown that proposed method gives equally acurate and precise results even ill the presence of ester functional group.",
publisher = "Marcel Dekker Inc, New York",
journal = "Stem Cells Translational Medicine",
title = "Spectrophotometric determination of certain cephalosporins using ferrihydroxamate method",
volume = "30",
number = "2",
pages = "309-319",
doi = "10.1080/00387019708006990"
}

Agbaba, D., Erić, S., Karljiković-Rajić, K., Vladimirov, S.,& Živanov-Stakić, D.. (1997). Spectrophotometric determination of certain cephalosporins using ferrihydroxamate method. in Stem Cells Translational Medicine
Marcel Dekker Inc, New York., 30(2), 309-319.
https://doi.org/10.1080/00387019708006990

Agbaba D, Erić S, Karljiković-Rajić K, Vladimirov S, Živanov-Stakić D. Spectrophotometric determination of certain cephalosporins using ferrihydroxamate method. in Stem Cells Translational Medicine. 1997;30(2):309-319.
doi:10.1080/00387019708006990 .

Agbaba, Danica, Erić, Slavica, Karljiković-Rajić, Katarina, Vladimirov, S, Živanov-Stakić, Dobrila, "Spectrophotometric determination of certain cephalosporins using ferrihydroxamate method" in Stem Cells Translational Medicine, 30, no. 2 (1997):309-319,
https://doi.org/10.1080/00387019708006990 . .