Pretraživanje
Prikaz rezultata 21-30 od 470
Liquid chromatography/tandem mass spectrometry for simultaneous determination of undeclared corticosteroids in cosmetic creams
(Wiley, Hoboken, 2015)
RationaleUndeclared corticosteroids in creams intended for frequent use might cause serious side-effects, especially in children. In order to prevent this or find the cause, it was essential to develop a method for quick ...
Pharmacokinetic Variability of Amikacin After Once-Daily and Twice-Daily Dosing Regimen in Full-Term Neonates
(Japanese Pharmacological Soc, Kyoto, 2014)
The purpose of the study was to compare peak (C-peak) and trough (C-trough) amikacin levels after twice-daily (TD) or once-daily dosing (OD) in full-term neonates. Additionally, the study aimed to address amikacin ...
Association between Adverse Effects and Parental Beliefs about Antiepileptic Medicines
(MDPI, Basel, 2018)
Background and Aim: Adverse effects are common in children treated with antiepileptic medications and may affect parental beliefs about treatment. The aim of the study was to investigate the relationship between adverse ...
High-Performance Liquid Chromatographic Determination of Pantoprazole and Its Main Impurities in Pharmaceuticals
(AOAC Int, Gaithersburg, 2010)
An RP-HPLC method for simultaneous separation and quantification of pantoprazole and its five main impurities in pharmaceutical formulations was developed and validated. The separation was accomplished on a Zorbax Eclipse ...
Assessment of Endothelial Dysfunction: The Role of Symmetrical Dimethylarginine and Proinflammatory Markers in Chronic Kidney Disease and Renal Transplant Recipients
(Hindawi Ltd, London, 2013)
Objectives. The study was designed to evaluate associations between symmetric dimethylarginine (SDMA), inflammation, and superoxide anion (O-2(center dot-)) with endothelial function and to determine their potential for ...
Influence of Solid Drug Delivery System Formulation on Poorly Water-Soluble Drug Dissolution and Permeability
(MDPI, Basel, 2015)
The majority of drugs have a low dissolution rate, which is a limiting step for their absorption. In this manuscript, solid dispersions (SD), solid self-microemulsifying drug delivery systems (S-SMEDDS) and solid ...
Pulmonary function, oxidative stress and inflammatory markers in severe COPD exacerbation
(W B Saunders Co Ltd, London, 2011)
Background: Oxidative stress and inflammation play an important role in the pathogenesis of chronic: obstructive pulmonary disease (COPD). Objective: Pulmonary function, oxidative stress parameters and inflammatory markers ...
Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 in Sepsis after Major Abdominal Surgery
(Hindawi Ltd, London, 2018)
Background. The role of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in sepsis after major abdominal surgery and sepsis-associated organ dysfunction is unexplored. Materials ...
How experimental details matter. The case of a laccase-catalysed oligomerisation reaction
(Royal Soc Chemistry, Cambridge, 2018)
The Trametes versicolor laccase (TvL)-catalysed oligomerisation of the aniline dimer p-aminodiphenylamine (PADPA) was investigated in an aqueous medium of pH = 3.5, containing 80-100 nm-sized anionic vesicles formed from ...
Positive modulation of alpha 5 GABA(A) receptors in preadolescence prevents reduced locomotor response to amphetamine in adult female but not male rats prenatally exposed to lipopolysaccharide
(Pergamon-Elsevier Science Ltd, Oxford, 2017)
We previously demonstrated that lipopolysaccharide (LPS) administered intraperitoneally (i.p.) to pregnant Wistar rat dams, at embryonic days 15 and 16 (E15/16), induced a decrease of baseline locomotor activity and ...