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Increased tumor necrosis factor alpha and interleukin-6 serum levels and their correlation with laboratory parameters in patients with imported Malaria
(Srpsko biološko društvo, Beograd, i dr., 2012)
In malaria, blood concentrations of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-alpha) and interleukin (IL)-6, are increased. In a study which included 34 patients, TNF-alpha and IL-6 were examined ...
Physicochemical Factors Governing the Partition of Pramipexole and Its Five Impurities in Microemulsion Liquid Chromatographic Systems
(Soc Brasileira Quimica, Sao Paulo, 2012)
Microemulsions when used as mobile phases represent a very powerful chromatographic tool due to their polyphase structure. The aim of this study was to investigate the influence of the mobile phase composition and resulting ...
Different Roles for Lactococcal Aggregation Factor and Mucin Binding Protein in Adhesion to Gastrointestinal Mucosa
(Amer Soc Microbiology, Washington, 2012)
Adhesion of bacteria to mucosal surfaces and epithelial cells is one of the key features for the selection of probiotics. In this study, we assessed the adhesion property of Lactococcus lactis subsp. lactis BGKP1 based on ...
Artificial neural networks in evaluation and optimization of modified release solid dosage forms
(MDPI, Basel, 2012)
Implementation of the Quality by Design (QbD) approach in pharmaceutical development has compelled researchers in the pharmaceutical industry to employ Design of Experiments (DoE) as a statistical tool, in product development. ...
Effects of oral and intraperitoneal magnesium treatment against cadmiuminduced oxidative stress in plasma of rats
(Inst Medical Research & Occupational Health, Zagreb, 2012)
Cadmium (Cd) has been recognised as one of the most important environmental and industrial pollutants, and up-to-date investigations have shown that one of the mechanisms of its toxicity is associated with the induction ...
Toxicity mechanisms and interactions of polychlorinated biphenyls and polybrominated diphenylethers / Mehanizmi toksičnog dejstva i interakcije polihlorovanih bifenila i polibromovanih difenil etara
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2012)
Polychlorinated biphenyls (PCBs) and brominated flame retardants, polybrominated diphenylethers (PBDEs), are widespread environmental contaminants as a result of anthropogenic activities and due to their persistency and ...
The effect of pre-treatment with l-name on glutathione and glutathione peroxidase in parquat-induced neurotoxicity in rat striatum / Efekat predtretmana sa l-name na glutation i glutation peroksidazu u strijatumu pacova na neurotoksičnost izazvanu parakvatom
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Contact herbicide paraquat (DQ) is bipyridylium compound, which undergoes redox metabolism; hence enlarged in humans radical production mediated its toxicity. Target organs of systemic effect of PQ poisoning are lung and ...
Radiopharmaceuticals for hepatobiliary scintigraphy: Iminodiacetic acid analogues labeled with technetium-99m / Radiofarmaceutici za hepatobilijarnu scintigrafiju - analozi iminodisirćetne kiseline obeleženi tehnecijumom-99m
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Hepatobiliary scintigraphy (Cholescintigraphy) is a nuclear imaging procedure for morphological and functional investigation of hepatobiliary system. 99mTc-IDA derivatives are commonly used for hepatobiliary imaging. ...
Development of Karl Fischer titration method using Duality by Design concept / Razvoj metode titracije po Karl Fišeru primenom tzv. Quality by Design koncepta
(Savez hemijskih inženjera, Beograd, 2012)
Modern trends in drug quality control are moving toward incorporating quality into the method during its development. That course is in accordance with Quality by Design (QbD) concept defined by ICH Q 8 (R2) guideline. ...
Analysis, adaptation and validation of the instrument for the competence evaluation of the pharmacists in community pharmacies / Analiza, adaptacija i validacija dokumenta za procenu kompetencija farmaceuta
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
The competency of a pharmacist is one of the fundamental preconditions for high quality pharmaceutical care provision. The General Lever Framework (GLF), which was developed by a group of British experts (Competency ...