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Vehicle-controlled effect of urea on normal and SLS-irritated skin
(Elsevier Science BV, Amsterdam, 2004)
It is known that, depending on the concentration, treatment with urea could improve skin barrier function, despite its penetration-enhancing properties. This controversial skin effect of urea has been explored systematically ...
Determination of S-carboxymethyl-L-cysteine, methylparaben and their degradation products in syrup preparations
(Springer Heidelberg, Heidelberg, 2004)
An HPLC method was developed for the determination of S-carboxymethyl-L-cysteine, methylparaben and related compounds in cough syrup preparations. The HPLC operating conditions used were acetonitrile-methanol-water ...
Determination of nisoldipine and its impurities in pharmaceuticals
(Springer Heidelberg, Heidelberg, 2004)
A method has been established for separation of nisoldipine and impurities, for example reactants, products of side-reactions, and photodegradation products, by HPTLC on LiChrospher Si 60 F-254s plates with detection at ...
3,5-nonadiyne isolated from the rhizome of Cachrys ferulacea inhibits endogenous nitric oxide release by rat peritoneal macrophages
(Pharmaceutical Soc Japan, Tokyo, 2004)
3,5-Nonadiyne, in vitro, selectively inhibits endogenous nitric oxide release (IC50=6.7 +/- 0.8 mum) by rat peritoneal macrophages at doses that do not inhibit T cell proliferation. 3,5-Nonadiyne was isolated from root ...
Disorders of hemostasis during the surgical management of severe necrotizing pancreatitis
(Lippincott Williams & Wilkins, Philadelphia, 2004)
Objectives: Several clinical studies of severe necrotizing pancreatitis ( SNP) suggest profound activation of coagulation as well as activation of the fibrinolytic system. The aim of this study was to evaluate the hemostatic ...
Catecholamines influence development of EAE
(Elsevier Science BV, Amsterdam, 2004)
Comparison of the relaxant effects of a new oxime-nitrate derived from isosorbide-5-mononitrate and the parent drug
(Georg Thieme Verlag Kg, Stuttgart, 2004)
The transformation of isosorbide-5-mononitrate (CAS 16051-77-7, IS-5-MN) to the corresponding keto derivative and its ketoxime (oxime-nitrate derivative of isosorbide) is described. The effects of IS-5-MN and the new ...
The synthesis of novel iodinated iminodiacetic acid analogues as hepatobiliary imaging agents
(Springer Wien, Vienna, 2004)
The synthesis and characterization of N-[2-[[4-iodo-2,6-bis(1-methylethyl)phenyl]amino]-2-oxoethyl]-N-(carboxymethyl)glycine and N-[2-[(4-iodo-2,6-diethylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine is presented, as ...
Characterization of caprylocaproyl macrogolglycerides based microemulsion drug delivery vehicles for an amphiphilic drug
(Elsevier Science BV, Amsterdam, 2004)
Microemulsion systems composed of water, isopropyl myristate, PEG-8 caprylic/captzc glycerides (Labrasol((R))), and polyglyceryl-6 dioleate (Plurol Oleique((R))), were investigated as potential drug delivery vehicles for ...
Orchidectomy affects the monoamine content in rat thymocytes
(Elsevier Science BV, Amsterdam, 2004)