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Mechanistic simulation of carbamazepine absorption after oral administration of immediate release tablets / In silico predviđanje apsorpcije karbamazepina nakon oralne primene tableta sa trenutnim oslobađanjem
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
The main prerequisite to establish quantitative in vitro-in vivo correlation (IVIVC) and define biorelevant in vitro methodology is to identify drug dissolution profile in vivo. When intravenous data are not available due ...
Adverse effects and toxicity of analgesics / Neželjeni efekti i toksičnost analgetika
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Even though among the most widely used analgoantipiretics with confirmed pharmacological effects, acetylsalicylic acid, paracetamol and ibuprofen may be the cause of poisonings and even death. Acetylsalicylic acid and ...
Effects of cosmetic active substances in the skin wrinkles treatment / Efekti kozmetički aktivnih supstanci u tretiranju kože zahvaćene borama
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
The ageing of skin occurs in all individuals at a variable rate which is influenced by genetic, environmental and hormonal factors. The ageing process can be divided into intrinsic ageing and extrinsic ageing. With increasing ...
Acute drug poisoning / Akutna trovanja lekovima
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Data collected from poison control centers indicate on millions of poisoning due to drug overdoses and acute drug poisonings represent one of the major causes of deaths. Groups of drugs that most commonly cause acute ...
Use of PROAST software to assess the influence of decabrominated diphenyl ether and/or cadmium on thyroid hormones homeostasis in rats / Primena PROAST softvera za ispitivanje uticaja dekabromovanog difeniletra i/ili kadmijuma na homeostazu hormona štitaste žlezde kod pacova
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
In relation to commonly used no-observed-adverse-effect-level (NOAEL) point of departure, because of its statistical power and reliability, Benchmark dose (BMD) approach has been proposed as an alternative in dose-response ...
Influence of hypertrigliceridemia on small, dense LDL and HDL particles in coronary artery disease / Uticaj hipertrigliceridemije na male, guste LDL i HDL čestice u koronarnoj arterijskoj bolesti
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Alterations in serum lipoprotein levels contribute to the progression of atherosclerosis in coronary artery disease (CAD). Screening for the presence of small, dense low-density (LDL) and high-density lipoprotein (HDL) ...
Psychoactive controlled substances: Current situation in the world / O psihoaktivnim kontrolisanim supstancama - situacija u svetu
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Although the psychoactive substances are strictly controlled in most of the countries in the world, their abuse is still very present, as confirmed by the data from the year of 2009 when over 200 million drug addicts were ...
Biologics: Pharmaceutical-technological specificities / Biološki lekovi - farmaceutsko-tehnološke specifičnosti
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
The field of pharmaceutical biotechnology is developing rapidly. For those working in the field of pharmacy and pharmaceutical sciences, completely new and novel techniques and product appear at a rapid pace, with an almost ...
The effect of pre-treatment with l-name on glutathione and glutathione peroxidase in parquat-induced neurotoxicity in rat striatum / Efekat predtretmana sa l-name na glutation i glutation peroksidazu u strijatumu pacova na neurotoksičnost izazvanu parakvatom
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Contact herbicide paraquat (DQ) is bipyridylium compound, which undergoes redox metabolism; hence enlarged in humans radical production mediated its toxicity. Target organs of systemic effect of PQ poisoning are lung and ...
Oxidative and nitrosative stress: Mediators of diquat neurotoxicity / Oksidativni i nitrozativni stres - medijatori neurotoksičnosti dikvata
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Most commonly observed central nervous system (CNS) effects induced by systemic toxicity of herbicide diquat (DQ) are general depression and lethargy. Generally, it is accepted that DQ exerts its toxicity through the ...