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Uticaj redoks disbalansa i inflamacije na aktivnost enzima paraoksonaze 1 i njegovu distribuciju na lipoproteinima visoke gustine u sindromu policističnih jajnika - efekat na kardiovaskularni rizik
(Универзитет у Београду, Фармацеутски факултет, 2018)
Sindrom policističnih jajnika (PCOS) je najčešći endokrinološki poremećaj kod žena u reproduktivnom periodu. Pored reproduktivnih poremećaja, ovaj sindrom karakterišu različite kardiometaboličke komplikacije kao što su ...
Association of Nrf2, SOD2 and GPX1 Polymorphisms with Biomarkers of Oxidative Distress and Survival in End-Stage Renal Disease Patients
(MDPI, 2019)
The oxidative stress response via Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) interlinks inflammation- and metabolism-related pathways in chronic kidney disease. We assessed the association between polymorphisms in ...
Glutathione S-transferase A1, M1, P1 and T1 null or low-activity genotypes are associated with enhanced oxidative damage among haemodialysis patients
(Oxford Univ Press, Oxford, 2013)
Background. Increased oxidative stress is a hallmark of end-stage renal disease (ESRD). Glutathione S-transferases (GST) are involved in the detoxification of xenobiotics and protection of oxidative damage. We hypothesized ...
Implications of oxidative stress in occupational exposure to lead on a cellular level
(Taylor & Francis Ltd, Abingdon, 2015)
The aim of this study was to determine oxidative alterations leading to cellular dysfunctions in Pb-exposed subjects by evaluating damage to all major classes of biomolecules in the cell, lipid peroxidation, protein and ...
Omega-3 fatty acids supplementation effects on paraoxonase-1 enzymatic activity
(Vup Food Research Inst, Bratislava, 2015)
Paraoxonase-1 activity (PON1) and expression modulation using different pharmacological, nutritional and life-style approaches are current scientific foci. We have assessed the influence of omega-3 fatty acids from different ...
Potential interaction of cadmium chloride with pancreatic mitochondria: Implications for pancreatic cancer
(Spandidos Publ Ltd, Athens, 2019)
Pancreatic cancer (PC) is insidious with a high mortality rate due to the lack of symptomology prior to diagnosis. Mitochondrial involvement in PC development is becoming accepted, and exposure to cadmium (Cd) is suspected ...
Toxic Effect of Acute Cadmium and Lead Exposure in Rat Blood, Liver, and Kidney
(MDPI, Basel, 2019)
Background: Cadmium and lead are widespread and non-biodegradable pollutants of great concern to human health. In real life scenarios, we are exposed to mixtures of chemicals rather than single chemicals, and it is therefore ...
EDTA chelation therapy decreases oxidative DNA damage in the blood cells of workers occupationaly exposed to lead / EDTA helatna terapija smanjuje oksidativno DNK oštećenje u limfocitima periferne krvi radnika profesionalno izloženih olovu
(Eko centar, centar za sociološka istraživanja i dokumentaciju, 2012)
INTRODUCTION: Pathogenetic effect of lead (Pb) is multifactorial and it is known that one of the ways which lead damages cellular components is by direct formation of reactive oxygen species. ...
Oksidativno-stresni status u krvi i lipoproteinskim frakcijama pacijenata sa hroničnom bolešću bubrega
(Универзитет у Београду, Фармацеутски факултет, 2018)
Hronična bolest bubrega (HBB) predstavlja stanje koje se karakteriše brojnim tradicionalnim i netradicionalnim faktorima rizika za razvoj kardiovaskularnih bolesti (KVB). Dislipidemija, oksidativni stres i ...
Effect of Astaxanthin Supplementation on Paraoxonase 1 Activities and Oxidative Stress Status in Young Soccer Players
(Wiley-Blackwell, Hoboken, 2013)
The purpose of the study was to examine the effects of astaxanthin (Asx) on paraoxonase (PON1) activities and oxidative stress status in soccer players. Forty soccer players were randomly assigned in a double-blind fashion ...