Search
Now showing items 1-10 of 10
A hazardous link between malnutrition, inflammation and oxidative stress in renal patients
(Pergamon-Elsevier Science Ltd, Oxford, 2012)
Background: Atherosclerosis is the main cause of mortality in end stage renal disease (ESRD) patients. Design and methods: Malnutrition, inflammation and diminished paraoxonase activity were used to calculate the sum of ...
Sex Bias in Pathogenesis of Autoimmune Neuroinflammation: Relevance for Dimethyl Fumarate Immunomodulatory/Anti-oxidant Action
(Springer, New York, 2018)
In the present study, upon showing sexual dimorphism in dimethyl fumarate (DMF) efficacy to moderate the clinical severity of experimental autoimmune encephalomyelitis (EAE) in Dark Agouti rats, cellular and molecular ...
Polychlorinated biphenyls as oxidative stress inducers in liver of subacutely exposed rats: Implication for dose-dependence toxicity and benchmark dose concept
(Academic Press Inc Elsevier Science, San Diego, 2015)
Hepatotoxicity is one of the well-documented adverse health effects of polychlorinated biphenyls (PCBs)persistent organic pollutants widely present in the environment. Although previous studies suggest possible role of ...
Oxidative stress and paraoxonase 1 status in acute ischemic stroke patients
(Elsevier Ireland Ltd, Clare, 2015)
Objective: The connection of oxidative stress with dyslipidemia creates a newly-emerging atherosclerosis risk factor involved in acute ischemic stroke development. This study analyzed the influence of oxidative stress on ...
Evaluation of cytogenetic and DNA damage in human lymphocytes treated with adrenaline in vitro
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Catechol groups can be involved in redox cycling accompanied by generation of reactive oxygen species (ROS) which may lead to oxidative damage of cellular macromolecules including DNA. The objective of this investigation ...
Association of paraoxonase 1 and oxidative stress with acute kidney injury in premature asphyxiated neonates
(Elsevier Ireland Ltd, Clare, 2017)
Objectives: Acute kidney injury (AKI) is defined as a decrease in glomerular filtration rate with an increase in serum creatinine (sCr). Perinatal asphyxia (PNA) may be etiological factor for AKI with oxidative stress also ...
Markers of Oxidative Stress and Endothelial Dysfunction Predict Haemodialysis Patients Survival
(S. Karger AG, 2019)
Introduction: Overall survival of patients with end-stage renal disease (ESRD) remains poor. Oxidative stress is one of the major risk factors associated with mortality in this patient group. As glutathione S-transferases ...
Insight into the oxidative stress induced by lead and/or cadmium in blood, liver and kidneys
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Besides being important occupational hazards, lead and cadmium are nowadays metals of great environmental concern. Both metals, without any physiological functions, can induce serious adverse health effects in various ...
Older age and HDL-cholesterol as independent predictors of liver fibrosis assessed by BARD score
(Edizioni Minerva Medica, Turin, 2019)
BACKGROUND: It is known that non-alcoholic fatty liver disease (NAFLD), and in particular non-alcoholic steatohepatitis, can progress to advanced fibrosis. However, pathophysiological mechanisms implicated in this evolution ...
Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease
(Springer, New York, 2013)
The roles of dyslipidemia and oxidative stress in the early phases of atherosclerosis were tested in children with chronic kidney disease (CKD). Intima media thickness of common carotid arteries (cIMT) is used as a measure ...